Articles

Radiotherapy-induced toxicity in prostate cancer patients with hip prostheses

Acute and late toxicity was analysed for prostate cancer patients with bilateral hip prostheses, who received fixed field intensity modulated radiotherapy (IMRT). The aims were (1) to establish whether toxicit...

Authors: Andrea M. Fischer and Peter J. Hoskin

MR-guided SBRT boost for patients with locally advanced or recurrent gynecological cancers ineligible for brachytherapy: feasibility and early clinical experience

Chemoradiotherapy (CRT) followed by a brachytherapy (BT) boost is the standard of care for patients with locally advanced or recurrent gynecological cancer (LARGC). However, not every patient is suitable for B...

Authors: Indrawati Hadi, Chukwuka Eze, Stephan Schönecker, Rieke von Bestenbostel, Paul Rogowski, Lukas Nierer, Raphael Bodensohn, Michael Reiner, Guillaume Landry, Claus Belka, Maximilian Niyazi and Stefanie Corradini

Predicting factors of symptomatic radiation pneumonitis induced by durvalumab following concurrent chemoradiotherapy in locally advanced non-small cell lung cancer

Concurrent chemoradiotherapy (CCRT) followed by durvalumab is the standard of care for unresectable locally-advanced non-small cell carcinoma (LA-NSCLC). However, a major concern about administration of durval...

Authors: Hiroshi Mayahara, Kazuyuki Uehara, Aya Harada, Keiji Kitatani, Tomonori Yabuuchi, Shuichirou Miyazaki, Takeaki Ishihara, Hiroki Kawaguchi, Hikaru Kubota, Hideaki Okada, Taira Ninomaru, Chihiro Shindo and Akito Hata

Prognostic value of tumor measurement parameters and SCC-Ag changes in patients with locally-advanced cervical cancer

To investigate the prognostic relevance of specific measurement parameters such as tumor diameter, tumor volume, tumor volume reduction rate (TVRR), and changes in the squamous cell carcinoma antigen (SCC-Ag) ...

Authors: Wenjuan Chen, Siyi Xiu, Xingyun Xie, Huiming Guo, Yuanji Xu, Penggang Bai and Xiaoyi Xia

Lung stereotactic body radiation therapy: personalized PTV margins according to tumor location and number of four-dimensional CT scans

To characterise the motion of pulmonary tumours during stereotactic body radiation therapy (SBRT) and to evaluate different margins when creating the planning target volume (PTV) on a single 4D CT scan (4DCT).

Authors: Pierre Trémolières, Ana Gonzalez-Moya, Amaury Paumier, Martine Mege, Julien Blanchecotte, Christelle Theotime, Damien Autret and Stéphane Dufreneix

An algorithm for thoracic re-irradiation using biologically effective dose: a common language on how to treat in a “no-treat zone”

Re-irradiation (re-RT) is a technically challenging task for which few standardized approaches exist. This is in part due to the lack of a common platform to assess dose tolerance in relation to toxicity in th...

Authors: Eric D. Brooks, Xiaochun Wang, Brian De, Vivek Verma, Tyler D. Williamson, Rachel Hunter, Abdallah S. R. Mohamed, Matthew S. Ning, Xiaodong Zhang and Joe Y. Chang

A pilot study of machine-learning based automated planning for primary brain tumours

High-quality radiotherapy (RT) planning for children and young adults with primary brain tumours is essential to minimize the risk of late treatment effects. The feasibility of using automated machine-learning...

Authors: Derek S. Tsang, Grace Tsui, Chris McIntosh, Thomas Purdie, Glenn Bauman, Hitesh Dama, Normand Laperriere, Barbara-Ann Millar, David B. Shultz, Sameera Ahmed, Mohammad Khandwala and David C. Hodgson

Gastric side effects and the stomach dosimetric analysis in left-sided breast cancer radiotherapy in free-breathing and deep inspiration breath-hold technique

Adjuvant radiotherapy following surgery reduces the local recurrence and improves the prognosis. However, a considerable part of patients developed digestive reaction in daily treatment. In order to explore th...

Authors: Dong Yang, Ying Piao, Fengshun Yuan, Hongtao Chen, Ding Zhang and Xianming Li

Evaluation of plan robustness on the dosimetry of volumetric arc radiotherapy (VMAT) with set-up uncertainty in Nasopharyngeal carcinoma (NPC) radiotherapy

To evaluate the sensitivity to set up the uncertainty of VMAT plans in Nasopharyngeal carcinoma (NPC) treatment by proposing a plan robustness evaluation method.

Authors: Zhen Ding, Xiaoyong Xiang, Qi Zeng, Jun Ma, Zhitao Dai, Kailian Kang and Suyan Bi

Evaluation of a treatment planning system developed for clinical boron neutron capture therapy and validation against an independent Monte Carlo dose calculation system

Boron neutron capture therapy (BNCT) for the treatment of unresectable, locally advanced, and recurrent carcinoma of the head and neck cancer has been approved by the Japanese government for reimbursement unde...

Authors: Naonori Hu, Hiroki Tanaka, Ryo Kakino, Syuushi Yoshikawa, Mamoru Miyao, Kazuhiko Akita, Kayako Isohashi, Teruhito Aihara, Keiji Nihei and Koji Ono

Vertebral body and splenic irradiation are associated with lymphopenia in localized pancreatic cancer treated with stereotactic body radiation therapy

The purpose of this study was to determine if vertebral body and splenic dosimetry was associated with the development of lymphopenia in patients with borderline resectable (BRPC) and locally advanced pancreat...

Authors: Abhinav V. Reddy, Matthew P. Deek, Juan F. Jackson, Colin S. Hill, Shuchi Sehgal, Jin He, Lei Zheng, Joseph M. Herman, Jeffrey Meyer and Amol K. Narang

Heart atlas for retrospective cardiac dosimetry: a multi-institutional study on interobserver contouring variations and their dosimetric impact

Cardiac effects after breast cancer radiation therapy potentially affect more patients as survival improves. The heart’s heterogeneous radiation exposure and composition of functional structures call for estab...

Authors: Marcus Stockinger, Heiko Karle, Hannes Rennau, Sabine Sebb, Ulrich Wolf, Julia Remmele, Sandra Bührdel, Detlef Bartkowiak, Maria Blettner, Heinz Schmidberger and Daniel Wollschläger

Glioblastoma radiotherapy using Intensity modulated Radiotherapy (IMRT) or proton Radiotherapy—GRIPS Trial (Glioblastoma Radiotherapy via IMRT or Proton BeamS): a study protocol for a multicenter, prospective, open-label, randomized, two-arm, phase III study

Radiation therapy is an integral part of the multimodal primary therapy of glioblastomas. As the overall prognosis in this tumor entity remains unfavorable, current research is focused on additional drug thera...

Authors: Laila König, Cornelia Jäkel, Nikolaus von Knebel Doeberitz, Meinhard Kieser, Fabian Eberle, Marc Münter, Jürgen Debus and Klaus Herfarth

Three weekly versus weekly concurrent cisplatin: safety propensity score analysis on 166 head and neck cancer patients

Radio-chemotherapy with CDDP is the standard for H&N squamous cell cancer. CDDP 100 mg/m²/q3 is the standard; alternative schedules are used to reduce toxicity, mostly 40 mg/m²/q1.

Authors: Michela Buglione, Daniela Alterio, Marta Maddalo, Diana Greco, Marianna Alessandra Gerardi, Davide Tomasini, Ludovica Pegurri, Matteo Augugliaro, Giulia Marvaso, Irene Turturici, Andrea Guerini, Mohssen Ansarin, Luigi Spiazzi, Loredana Costa, Maria Cossu Rocca, Stefano Maria Magrini…

Proton therapy with a fixed beamline for skull-base chordomas and chondrosarcomas: outcomes and toxicity

This study presents an analysis (efficacy and toxicity) of outcomes in patients with skull-base chordomas or chondrosarcomas treated with a fixed horizontal pencil proton beam.

Authors: Konstantin Gordon, Igor Gulidov, Sergey Koryakin, Daniil Smyk, Tatyana Makeenkova, Danil Gogolin, Olga Lepilina, Olga Golovanova, Alexey Semenov, Sergey Dujenko, Kira Medvedeva and Yuri Mardynsky

Delta radiomics analysis of Magnetic Resonance guided radiotherapy imaging data can enable treatment response prediction in pancreatic cancer

Magnetic Resonance Image guided Stereotactic body radiotherapy (MRgRT) is an emerging technology that is increasingly used in treatment of visceral cancers, such as pancreatic adenocarcinoma (PDAC). Given the ...

Authors: M. R. Tomaszewski, K. Latifi, E. Boyer, R. F. Palm, I. El Naqa, E. G. Moros, S. E. Hoffe, S. A. Rosenberg, J. M. Frakes and R. J. Gillies

Feasibility study of volumetric modulated arc therapy with Halcyon™ linac for total body irradiation

The use of total body irradiation (TBI) with linac-based volumetric modulated arc therapy (VMAT) has been steadily increasing. Helical tomotherapy has been applied in TBI and total marrow irradiation to reduce...

Authors: Takuya Uehara, Hajime Monzen, Mikoto Tamura, Masahiro Inada, Masakazu Otsuka, Hiroshi Doi, Kenji Matsumoto and Yasumasa Nishimura

Prostate deformation during hypofractionated radiotherapy: an analysis of implanted fiducial marker displacement

To report prostate deformation during treatment, based on an analysis of fiducial marker positional differences in a large sample.

Authors: Lukas Knybel, Jakub Cvek, Tomas Blazek, Andrea Binarova, Tereza Parackova and Kamila Resova

Analytical setup margin for spinal stereotactic body radiotherapy based on measured errors

No consensus currently exists about the correct margin size to use for spinal SBRT. Margins have been proposed to account for various errors individually, but not with all errors combined to result in a single...

Authors: Audrey Copeland, Addie Barron and Jonas Fontenot

Therapeutic effect of osimertinib plus cranial radiotherapy compared to osimertinib alone in NSCLC patients with EGFR-activating mutations and brain metastases: a retrospective study

The study aimed to compare the efficacy of osimertinib plus cranial radiotherapy (RT) with osimertinib alone in advanced non-small-cell lung cancer (NSCLC) patients harboring epidermal growth factor receptor (...

Authors: Xiaoyang Zhai, Wanhu Li, Ji Li, Wenxiao Jia, Wang Jing, Yaru Tian, Shuhui Xu, Yuying Li, Hui Zhu and Jinming Yu

A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device

Intensity-modulated radiation therapy (IMRT) and volume-modulated arc therapy (VMAT) are rather complex treatment techniques and require patient-specific quality assurance procedures. Electronic portal imaging...

Authors: Jun Zhang, Xiuqing Li, Miaomiao Lu, Qilin Zhang, Xile Zhang, Ruijie Yang, Maria F. Chan and Junhai Wen

Radiation pneumonitis in patients with non-small-cell lung cancer receiving chemoradiotherapy and an immune checkpoint inhibitor: a retrospective study

Immunotherapy has been administered to many patients with non-small-cell lung cancer (NSCLC). However, only few studies have examined toxicity in patients receiving an immune checkpoint inhibitor (ICI) after c...

Authors: Jeong Yun Jang, Su Ssan Kim, Si Yeol Song, Yeon Joo Kim, Sung-woo Kim and Eun Kyung Choi

Correction to: Durvalumab (MEDI 4736) in combination with extended neoadjuvant regimens in rectal cancer: a study protocol of a randomised phase II trial (PRIME-RT)

Authors: Catherine R. Hanna, Sean M. O’Cathail, Janet S. Graham, Mark Saunders, Leslie Samuel, Mark Harrison, Lynsey Devlin, Joanne Edwards, Daniel R. Gaya, Caroline A. Kelly, Liz-Anne Lewsley, Noori Maka, Paula Morrison, Louise Dinnett, Susan Dillon, Jacqueline Gourlay…

Selectively recommend ¹⁸F-FDG PET/CT for patients with de novo nasopharyngeal carcinoma in endemic areas

To identify the subset of patients with de novo nasopharyngeal carcinoma (NPC) for whom [¹⁸F] fluorodeoxyglucose positron emission tomography and computed tomography (¹⁸F-FDG PET/CT) should be recommended, and to...

Authors: Chuanben Chen, Ting Xu, Xiufang Qiu, Shihan Xie, Ziqing You, Yixin Hu, Yinghong Zheng, Zewei Liang, Chaoxiong Huang, Taojun Chen, Li Li, Jing Liu and Zhaodong Fei

Risk of developing second malignant neoplasms in patients with neuroblastoma: a population study of the US SEER database

Neuroblastoma is a common extracranial malignant tumor in children. Its main treatment modality is a combination of chemotherapy, radiotherapy, and surgery. Given the advances in chemotherapy regimens and the ...

Authors: Hongnan Zhen, Hui Guan, Jiabin Ma, Wenhui Wang, Shen Jing, Zheng Miao, Fuquan Zhang and Zhikai Liu

Continuity and coordination of care in highly selected chronic cancer patients treated with multiple repeat radiation therapy

As cancer is developing into a chronic disease due to longer survival, continuity and coordination of oncological care are becoming more important for patients. As radiation oncology departments are an integra...

Authors: Sebastian M. Christ, Maiwand Ahmadsei, Annina Seiler, Eugenia Vlaskou Badra, Jonas Willmann, Caroline Hertler and Matthias Guckenberger

Analysis of clinical patient-specific pre-treatment quality assurance with the new helical tomotherapy platform, following the AAPM TG-218 report

This study presents patient-specific quality assurance (QA) results from the first 395 clinical cases for the new helical TomoTherapy® platform (Radixact) coupled with dedicated Precision TPS.

Authors: Marco Fusella, Samuele Cavinato, Alessandra Germani, Marta Paiusco, Nicola Pivato, Marco Andrea Rossato, Anthony Scott and Alessandro Scaggion

Local control of bone metastases treated with external beam radiotherapy in recent years: a multicenter retrospective study

Over the past decades, remarkable advancements in systemic drug therapy have improved the prognosis of patients with bone metastases. Individualization is required in external beam radiotherapy (EBRT) for bone...

Authors: Kenji Makita, Yasushi Hamamoto, Hiromitsu Kanzaki, Masaaki Kataoka, Shuhei Yamamoto, Kei Nagasaki, Hirofumi Ishikawa, Noriko Takata, Shintaro Tsuruoka, Kotaro Uwatsu and Teruhito Kido

A bi-institutional multi-disciplinary failure mode and effects analysis (FMEA) for a Co-60 based total body irradiation technique

We aim to assess the risks associated with total body irradiation (TBI) delivered using a commercial dedicated Co-60 irradiator, and to evaluate inter-institutional and inter-professional variations in the est...

Authors: Shahbaz Ahmed, Todd Bossenberger, Adrian Nalichowski, Jeremy S. Bredfeldt, Sarah Bartlett, Kristen Bertone, Michael Dominello, Mark Dziemianowicz, Melanie Komajda, G. Mike Makrigiorgos, Karen J. Marcus, Andrea Ng, Marvin Thomas and Jay Burmeister

Explore association of genes in PDL1/PD1 pathway to radiotherapy survival benefit based on interaction model strategy

To explore the association of genes in “PD-L1 expression and PD-1 check point pathway in cancer” to radiotherapy survival benefit.

Authors: Junjie Shen, Jingfang Liu, Huijun Li, Lu Bai, Zixuan Du, Ruirui Geng, Jianping Cao, Peng Sun and Zaixiang Tang

Treatment outcomes of re-irradiation using stereotactic ablative radiotherapy to lung: a propensity score matching analysis

The purpose of this study was to compare the treatment efficacy and safety of re-irradiation (re-RT) using stereotactic ablative radiotherapy (SABR) and initial SABR for primary, recurrent lung cancer or metas...

Authors: Tae Hoon Lee, Dong-Yun Kim, Hong-Gyun Wu, Joo Ho Lee and Hak Jae Kim

Simultaneous radiosurgery for multiple brain metastases: technical overview of the UCLA experience

To communicate our institutional experience with single isocenter radiosurgery treatments for multiple brain metastases, including challenges with determining planning target volume (PTV) margins and resulting...

Authors: Nzhde Agazaryan, Steve Tenn, Chul Lee, Michael Steinberg, John Hegde, Robert Chin, Nader Pouratian, Isaac Yang, Won Kim and Tania Kaprealian

Biological dosiomic features for the prediction of radiation pneumonitis in esophageal cancer patients

The purpose of this study was to develop a model using dose volume histogram (DVH) and dosiomic features to predict the risk of radiation pneumonitis (RP) in the treatment of esophageal cancer with radiation t...

Authors: Chanon Puttanawarut, Nat Sirirutbunkajorn, Suphalak Khachonkham, Poompis Pattaranutaporn and Yodchanan Wongsawat

Omitting surgery in esophageal cancer patients with complete response after neoadjuvant chemoradiotherapy: a systematic review and meta-analysis

Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is a standard treatment modality for locally-advanced esophageal cancer. However, patients who achieve clinical complete response (cCR) after nCRT have ...

Authors: Jaehyeon Park, Ji Woon Yea, Se An Oh and Jae Won Park

Oesophageal IGRT considerations for SBRT of LA-NSCLC: barium-enhanced CBCT and interfraction motion

To determine the optimal volume of barium for oesophageal localisation on cone-beam CT (CBCT) for locally-advanced non-small cell lung cancers (NSCLC) and quantify the interfraction oesophageal movement relati...

Authors: Katrina Woodford, Vanessa Panettieri, Jeremy D. Ruben, Sidney Davis, Trieumy Tran Le, Stephanie Miller and Sashendra Senthi

Operating procedures, risk management and challenges during implementation of adaptive and non-adaptive MR-guided radiotherapy: 1-year single-center experience

Main purpose was to describe procedures and identify challenges in the implementation process of adaptive and non-adaptive MR-guided radiotherapy (MRgRT), especially new risks in workflow due to the new techni...

Authors: Helena Isabel Garcia Schüler, Matea Pavic, Michael Mayinger, Nienke Weitkamp, Madalyne Chamberlain, Cäcilia Reiner, Claudia Linsenmeier, Panagiotis Balermpas, Jerome Krayenbühl, Matthias Guckenberger, Michael Baumgartl, Lotte Wilke, Stephanie Tanadini-Lang and Nicolaus Andratschke

The basis and advances in clinical application of boron neutron capture therapy

Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for cancer treatment that selecti...

Authors: Huifang He, Jiyuan Li, Ping Jiang, Suqing Tian, Hao Wang, Ruitai Fan, Junqi Liu, Yuyan Yang, Zhibo Liu and Junjie Wang

Efficacy of concurrent chemoradiotherapy in subgroups of stage III nasopharyngeal carcinoma: an analysis based on 10-year follow-up

To evaluate the efficacy of concurrent chemoradiotherapy (CCRT) in subgroups of stage III nasopharyngeal carcinoma (NPC) in the context of intensity-modulated radiotherapy (IMRT).

Authors: Lei Wang, Zheng Wu, Wanqin Cheng, Dehuan Xie, Feifei Lin, Liangping Xia and Yong Su

Correction to: ¹²⁵I seeds irradiation inhibits tumor growth and induces apoptosis by Ki-67, P21, survivin, livin and caspase-9 expression in lung carcinoma xenografts

Authors: Qing Jin, Cunzhi Lin, Xinhong Zhu, Yiwei Cao, Caihong Guo and Lijun Wang

Comparison of sliding window and field-in-field techniques for tangential whole breast irradiation using the Halcyon and Synergy Agility systems

To implement a tangential treatment technique for whole breast irradiation using the Varian Halcyon and to compare it with Elekta Synergy Agility plans.

Authors: Anne Richter, Sonja Wegener, Kathrin Breuer, Gary Razinskas, Stefan Weick, Florian Exner, Klaus Bratengeier, Michael Flentje, Otto Sauer and Bülent Polat

Gastrointestinal and genitourinary toxicity profiles of metformin versus placebo in men with prostate cancer receiving prostate radiotherapy: interim toxicity results of a double-blinded, multicenter, phase II randomized controlled trial

Androgen deprivation therapy (ADT) used for prostate cancer (PCa) management is associated with metabolic and anthropometric toxicity. Metformin given concurrent to ADT is hypothesized to counteract these chan...

Authors: Julian O. Kim, Megan O. McDonald, Aldrich Ong, Rashmi Koul, Arbind Dubey, William Hunter, Shahida Ahmed, Harvey Quon, Don Yee, Matthew Parliament, Gokulan Sivananthan, Brita Danielson, Lindsay Rowe, Sunita Ghosh and Nawaid Usmani

Stereotactic body radiotherapy in combination with non-frontline PD-1 inhibitors and targeted agents in metastatic renal cell carcinoma

Radiotherapy may work synergistically with immunotherapy and targeted agents. We aimed to assess the safety and outcomes of stereotactic body radiotherapy (SBRT) plus non-first-line programmed death-1 (PD-1) i...

Authors: Yang Liu, Zhiling Zhang, Ruiqi Liu, Wensu Wei, Zitong Zhang, Lixin Mai, Shengjie Guo, Hui Han, Fangjian Zhou, Liru He and Pei Dong

Accelerated coronary calcium burden in breast cancer patients after radiotherapy: a comparison with age and race matched healthy women

Radiotherapy (RT) might lead to atherosclerotic plaque buildup and coronary artery stenosis of breast cancer (BC) survivors, and coronary artery calcium (CAC) might be a sign of preclinical atherosclerosis. Th...

Authors: Yu-Hsuan Lai, Helen H. W. Chen and Yi-Shan Tsai

Prospective superficial EPR in-vivo dosimetry study during hypofractionated radiotherapy of breast cancer patients treated with helical tomotherapy

In-vivo dosimetry (IVD) is a patient specific measure of quality control and safety during radiotherapy. With regard to current reporting thresholds for significant occurrences in radiotherapy defined by Germa...

Authors: Sebastian Höfel, Matteo Gandalini, Michael K. Fix, Malte Drescher and Felix Zwicker

Long-term cancer survivors treated with multiple courses of repeat radiation therapy

Through recent advances in cancer care, the number of long-term survivors has continuously increased. As a result, repetitive use of local radiotherapy for curative or palliative indications might have increas...

Authors: Sebastian M. Christ, Maiwand Ahmadsei, Lotte Wilke, Anja Kühnis, Matea Pavic, Stephanie Tanadini-Lang and Matthias Guckenberger

Benefit of chemotherapy based on platinum with definitive radiotherapy in older patients with locally advanced esophageal squamous cell carcinoma

There is still no definitely therapeutic evidence of a beneficial effect of chemotherapy with radiotherapy for older patients with esophageal squamous cell carcinoma (ESCC). We aim to determine the influence o...

Authors: Haishan Wu, Yilin Yu, Qunhao Zheng, Tianxiu Liu, Yahua Wu, Zhiping Wang, Hongying Zheng, Lingyun Liu and Jiancheng Li

A systematic study of independently-tuned room-specific PBS beam model in a beam-matched multiroom proton therapy system

In the existing application of beam-matched multiroom proton therapy system, the model based on the commissioning data from the leading treatment room was used as the shared model. The purpose of this study is...

Authors: Yu-Hua Huang, Chunfeng Fang, Tao Yang, Lin Cao, Gaolong Zhang, Baolin Qu, Yihang Zhang, Zishen Wang and Shouping Xu

Cone beam CT-based dose accumulation and analysis of delivered dose to the dominant intraprostatic lesion in primary radiotherapy of prostate cancer

Evaluation of delivered dose to the dominant intraprostatic lesion (DIL) for moderately hypofractionated radiotherapy of prostate cancer by cone beam computed tomography (CBCT)-based dose accumulation and targ...

Authors: Jörg Tamihardja, Sinan Cirsi, Patrick Kessler, Gary Razinskas, Florian Exner, Anne Richter, Bülent Polat and Michael Flentje

Medical student education through flipped learning and virtual rotations in radiation oncology during the COVID-19 pandemic: a cross sectional research

The COVID-19 pandemic has stripped many medical students worldwide of their right to quality education. In response, we developed hybrid courses involving aspects of both online and in-person teaching for radi...

Authors: Tae Hyung Kim, Jin Sung Kim, Hong In Yoon, Joongyo Lee, Jason Joon Bock Lee, Hwa Kyung Byun, Yeona Cho, Yong Bae Kim, Ik Jae Lee, Kyung Hwan Kim and Jee Suk Chang

Evaluation of deep learning-based autosegmentation in breast cancer radiotherapy

To study the performance of a proposed deep learning-based autocontouring system in delineating organs at risk (OARs) in breast radiotherapy with a group of experts.

Authors: Hwa Kyung Byun, Jee Suk Chang, Min Seo Choi, Jaehee Chun, Jinhong Jung, Chiyoung Jeong, Jin Sung Kim, Yongjin Chang, Seung Yeun Chung, Seungryul Lee and Yong Bae Kim