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  1. The treatment for brain metastases in small cell lung cancer (SCLC) is still controversial. The purpose of this study was to compare different brain radiotherapy treatments on SCLC patients with brain metastases.

    Authors: Meng Ni, Aijun Jiang, Wenju Liu, Yanxing Sheng, Haiyan Zeng, Ning Liu, Qingxiao Gao, Yong Wang, Jinming Yu and Shuanghu Yuan

    Citation: Radiation Oncology 2020 15:70

    Content type: Research

    Published on:

  2. Unity Elekta is a unique magnetic resonance (MR)-linac that conjugates a 1.5 Tesla MR unit with a 7 MV flattening filter free accelerator.A prospective observational study for the clinical use of Elekta Unity ...

    Authors: Filippo Alongi, Michele Rigo, Vanessa Figlia, Francesco Cuccia, Niccolò Giaj-Levra, Luca Nicosia, Francesco Ricchetti, Gianluisa Sicignano, Antonio De Simone, Stefania Naccarato, Ruggero Ruggieri and Rosario Mazzola

    Citation: Radiation Oncology 2020 15:69

    Content type: Research

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  3. We investigated the risk factors of radiation-induced thyroid dysfunction, then combined the clinical factors and optimum thyroid dosimetric parameters to predict the incidence rate of hypothyroidism (HT) and ...

    Authors: Ling Zhou, Jia Chen, Wei Shen, Zheng-Lu Chen, Shuang Huang, Chang-Juan Tao, Ming Chen, Zhong-Hua Yu and Yuan-Yuan Chen

    Citation: Radiation Oncology 2020 15:68

    Content type: Research

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  4. Hypofractionated whole-breast irradiation is a standard adjuvant therapy for early-stage breast cancer. This study evaluates the plan quality and efficacy of an in-house-developed automated radiotherapy treatm...

    Authors: Ting-Chun Lin, Chih-Yuan Lin, Kai-Chiun Li, Jin-Huei Ji, Ji-An Liang, An-Cheng Shiau, Liang-Chih Liu and Ti-Hao Wang

    Citation: Radiation Oncology 2020 15:67

    Content type: Research

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  5. This study directs to evaluate the efficacy and safety of intensity-modulated radiotherapy (IMRT) alone versus IMRT plus chemotherapy in intermediate-risk NPC (stage II and T3N0M0).

    Authors: Omer Aftab, Shufang Liao, Rongjun Zhang, Nan Tang, Meiqing Luo, Bin Zhang, Sanjeev Shahi, Raju Rai, Jazib Ali and Wei Jiang

    Citation: Radiation Oncology 2020 15:66

    Content type: Research

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  6. We evaluated the relationship between patient-, tumor-, and treatment-related features and radiation-induced lymphopenia (RIL) and evaluated the correlation between RIL and survival outcome in NPC patients to ...

    Authors: Xiaoxue Xie, Shenglan Gong, Hekun Jin, Pei Yang, Ting Xu, Yilong Cai, Chengxian Guo, Rong Zhang, Fan Lou, Wenjuan Yang and Hui Wang

    Citation: Radiation Oncology 2020 15:65

    Content type: Research

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  7. This work aims at clinically validating a graphical tool developed for treatment plan assessment, named SPIDERplan, by comparing the plan choices based on its scoring with the radiation oncologists (RO) clinic...

    Authors: Tiago Ventura, Joana Dias, Leila Khouri, Eduardo Netto, André Soares, Brigida da Costa Ferreira, Humberto Rocha and Maria do Carmo Lopes

    Citation: Radiation Oncology 2020 15:64

    Content type: Research

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  8. To assess the safety and efficacy of CyberKnife® radiotherapy (CKRT) for the treatment of olfactory groove meningiomas (OGMs).

    Authors: Jianmin Liu, Rafael Rojas, Fred C. Lam, Farhan A. Mirza, Anand Mahadevan and Ekkehard M. Kasper

    Citation: Radiation Oncology 2020 15:63

    Content type: Research

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  9. Advances in therapy have resulted in improved cure rates and an increasing number of long-term Hodgkin's lymphoma (HL) survivors. However, radiotherapy (RT)-related late effects are still a significant issue, ...

    Authors: Andrea Riccardo Filippi, Sofia Meregalli, Anna DI Russo, Mario Levis, Patrizia Ciammella, Michela Buglione, Andrea Emanuele Guerini, Giuseppina De Marco, Vitaliana De Sanctis, Stefano Vagge, Umberto Ricardi and Gabriele Simontacchi

    Citation: Radiation Oncology 2020 15:62

    Content type: Review

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  10. To compare treatment plans for interstitial high dose rate (HDR) liver brachytherapy with 192Ir calculated according to current-standard TG-43U1 protocol with model-based dose calculation following TG-186 protoco...

    Authors: Anna Sophie Duque, Stefanie Corradini, Florian Kamp, Max Seidensticker, Florian Streitparth, Christopher Kurz, Franziska Walter, Katia Parodi, Frank Verhaegen, Jens Ricke, Claus Belka, Gabriel Paiva Fonseca and Guillaume Landry

    Citation: Radiation Oncology 2020 15:60

    Content type: Research

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  11. Limiting the heart dose in left sided breast cancer radiotherapy is critical. We sought to study the effect of using CPAP (continuous positive airway pressure) as an aid in reducing heart dose in breast cancer...

    Authors: Aaron M. Allen, Yasmin Korzets Ceder, Tzippy Shochat, Eyal Fenig, Aron Popovtzer, Dimitry Bragilofsky, Adi Alfassy and Helena Allon

    Citation: Radiation Oncology 2020 15:59

    Content type: Research

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  12. Sublethal radiation induces matrix metalloproteinase 9 (MMP-9)-mediated radioresistance in Lewis lung carcinoma (LLC) cells and their metastatic dissemination. We aim to determine if EGFR/HER2 activation assoc...

    Authors: Yun Tien, Chiao-Ling Tsai, Wei-Hsien Hou, Yun Chiang, Feng-Ming Hsu, Yu-Chieh Tsai and Jason Chia-Hsien Cheng

    Citation: Radiation Oncology 2020 15:58

    Content type: Research

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  13. To quantify tumor anatomic change of non-small cell lung cancer (NSCLC) patients given passive-scattering proton therapy (PSPT) and intensity-modulated radiation therapy (IMRT) through 6–7 weeks of treatment, ...

    Authors: Mei Chen, Jinzhong Yang, Zhongxing Liao, Jiayi Chen, Cheng Xu, Xiaodong He, Xiaodong Zhang, Ronald X. Zhu and Heng Li

    Citation: Radiation Oncology 2020 15:55

    Content type: Research

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  14. The internal target volume (ITV) approach and the mid-ventilation (MidV) concept are the two main respiratory motion-management strategies under free breathing. The purpose of this work was to compare the actu...

    Authors: J. Bellec, F. Arab-Ceschia, J. Castelli, C. Lafond and E. Chajon

    Citation: Radiation Oncology 2020 15:54

    Content type: Research

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  16. The aim of the present study was to evaluate MRI response rate and clinical outcome of short-course radiotherapy (SCRT) on rectal cancer as an alternative to chemoradiotherapy in patients where downstaging is ...

    Authors: T. Koëter, S. G. C. van Elderen, G. F. A. J. B. van Tilborg, J. H. W. de Wilt, D. K. Wasowicz, T. Rozema and D. D. E. Zimmerman

    Citation: Radiation Oncology 2020 15:53

    Content type: Research

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  17. Three-dimensional Surface Imaging (3DSI) is a well-established method to objectively monitor morphological changes in the female breast in the field of plastic surgery. In contrast, in radiation oncology we ar...

    Authors: Konstantin Christoph Koban, Lucas Etzel, Zhouxiao Li, Montserrat Pazos, Stephan Schönecker, Claus Belka, Riccardo Enzo Giunta, Thilo Ludwig Schenck and Stefanie Corradini

    Citation: Radiation Oncology 2020 15:52

    Content type: Research

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  18. For stereotactic body radiotherapy (SBRT) to central (C) and ultracentral (UC) lung tumors, our provincial practice has been to prioritize organs at risk (OARs) constraints by compromising target volume covera...

    Authors: Yizhou Zhao, Eman Khawandanh, Steven Thomas, Susan Zhang, Emma M. Dunne, Mitchell Liu and Devin Schellenberg

    Citation: Radiation Oncology 2020 15:61

    Content type: Research

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  19. Neoadjuvant radiotherapy (RT) has been shown to improve local control; however, whether it can improve overall survival (OS) in locally advanced rectal cancer (LARC) patients remains controversial. We therefor...

    Authors: Feng Zhao, Jili Wang, Hao Yu, Xiaofei Cheng, Xinke Li, Xuan Zhu, Xiangming Xu, Jianjiang Lin, Xin Chen and Senxiang Yan

    Citation: Radiation Oncology 2020 15:49

    Content type: Research

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  20. The literature regarding pericardial effusion after definitive concurrent chemotherapy and intensity modulated radiotherapy (IMRT) for esophageal cancer was lacking. This study aimed to investigate the risk fa...

    Authors: Tzu-Hui Pao, Wei-Lun Chang, Nai-Jung Chiang, Chia-Ying Lin, Wu-Wei Lai, Yau-Lin Tseng and Forn-Chia Lin

    Citation: Radiation Oncology 2020 15:48

    Content type: Research

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  21. To investigate the consequences of residual setup error on target dose distribution using various image registration strategies for breast cancer treated with intensity-modulated proton therapy (IMPT).

    Authors: Xiaoying Liang, Raymond B. Mailhot Vega, Zuofeng Li, Dandan Zheng, Nancy Mendenhall and Julie A. Bradley

    Citation: Radiation Oncology 2020 15:47

    Content type: Research

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  22. To analyze patterns of failure in patients with LA-NSCLC who received definitive chemoradiotherapy (CRT) and to build a nomogram for predicting the failure patterns in this population of patients.

    Authors: Xueru Zhu, Runping Hou, Xiaoyang Li, Chang Jiang, Wuyan Xia and Xiaolong Fu

    Citation: Radiation Oncology 2020 15:43

    Content type: Research

    Published on:

  23. Although whole brain radiation therapy (WBRT) provides palliation and prophylaxis, reduces local recurrence probability and improves overall survival, it is evident that WBRT is associated with neurocognitive ...

    Authors: Adams Hei Long Yuen, Po Man Wu, Alex Kai Leung Li and Philip Chung Yin Mak

    Citation: Radiation Oncology 2020 15:42

    Content type: Research

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  24. The STAR-TReC trial is an international multi-center, randomized, phase II study assessing the feasibility of short-course radiotherapy or long-course chemoradiotherapy as an alternative to total mesorectal ex...

    Authors: Roy P. J. van den Ende, Femke P. Peters, Ernst Harderwijk, Heidi Rütten, Liza Bouwmans, Maaike Berbee, Richard A. M. Canters, Georgiana Stoian, Kim Compagner, Tom Rozema, Mariska de Smet, Martijn P. W. Intven, Rob H. N. Tijssen, Jacqueline Theuws, Paul van Haaren, Baukelien van Triest…

    Citation: Radiation Oncology 2020 15:41

    Content type: Research

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  25. On the elastic profiles of human teeth after radiotherapy for head and neck cancers, generation of dental complications, which may bring several side effects preventing the quality of life, has not well clarif...

    Authors: Irem Demirkan, Gokhan Yaprak, Cemile Ceylan, Emriye Algul, Ceyda Ozcakir Tomruk, Bukem Bilen and Mehmet Burcin Unlu

    Citation: Radiation Oncology 2020 15:38

    Content type: Research

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  26. There is limited data on the use of targeted or immunotherapy (TT/IT) in combination with single fraction stereotactic radiosurgery (SRS) in patients with melanoma brain metastasis (MBM). Therefore, we analyze...

    Authors: Indrawati Hadi, Olarn Roengvoraphoj, Raphael Bodensohn, Jan Hofmaier, Maximilian Niyazi, Claus Belka and Silke Birgit Nachbichler

    Citation: Radiation Oncology 2020 15:37

    Content type: Research

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  30. The development of radiation pneumonitis (RP) after Stereotactic Body Radiotherapy (SBRT) is known to be associated with many different factors, although historical analyses of RP have commonly utilized hetero...

    Authors: Jeffrey M. Ryckman, Michael Baine, Joseph Carmicheal, Ferdinand Osayande, Richard Sleightholm, Kaeli Samson, Dandan Zheng, Weining Zhen, Chi Lin and Chi Zhang

    Citation: Radiation Oncology 2020 15:33

    Content type: Research

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  31. In this study we have evaluated the accuracy of automatic, deformable structure propagation from planning CT and MR scans for daily online plan adaptation for MR linac (MRL) treatment, which is an important el...

    Authors: Rasmus Lübeck Christiansen, Lars Dysager, Anders Smedegaard Bertelsen, Olfred Hansen, Carsten Brink and Uffe Bernchou

    Citation: Radiation Oncology 2020 15:32

    Content type: Research

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  32. Head-and-neck squamous cell carcinoma (HNSCC) is one of the most common malignancies globally, and the number of elderly patients diagnosed with HNSCC is increasing. However, as elderly HNSCC patients are unde...

    Authors: Erik Haehl, Alexander Rühle, Hélène David, Tobias Kalckreuth, Tanja Sprave, Raluca Stoian, Christoph Becker, Andreas Knopf, Anca-Ligia Grosu and Nils H. Nicolay

    Citation: Radiation Oncology 2020 15:31

    Content type: Research

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  33. Local ablative treatment strategies are frequently offered to patients diagnosed with oligometastatic disease. Stereotactic body radiotherapy (SBRT), as ablative treatment option, is well established for lung ...

    Authors: Laila König, Matthias F. Häfner, Sonja Katayama, Stefan A. Koerber, Eric Tonndorf-Martini, Denise Bernhardt, Bastian von Nettelbladt, Fabian Weykamp, Philipp Hoegen, Sebastian Klüter, Matthew S. Susko, Jürgen Debus and Juliane Hörner-Rieber

    Citation: Radiation Oncology 2020 15:30

    Content type: Research

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  34. Following publication of the original article [1], we have been notified that the below text parts of the Discussion chapter should be changed.

    Authors: Kilian-Simon Baumann, Veronika Flatten, Uli Weber, Stefan Lautenschläger, Fabian Eberle, Klemens Zink and Rita Engenhart-Cabillic

    Citation: Radiation Oncology 2020 15:29

    Content type: Correction

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    The original article was published in Radiation Oncology 2019 14:183

  35. Colorectal cancer treatment requires a complex, multidisciplinary approach. Because of the potential variability, monitoring through clinical audits is advisable. This study assesses the effects of a quality i...

    Authors: M. G. Torras, E. Canals, C. Muñoz-Montplet, A. Vidal, D. Jurado, A. Eraso, S. Villà, M. Caro, J. Molero, M. Macià, M. Puigdemont, E. González-Muñoz, A. López, F. Guedea and J. M. Borras

    Citation: Radiation Oncology 2020 15:28

    Content type: Research

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  36. Small inter- and intrafractional prostate motion was shown to be a prerequisite for precise radiotherapy (RT) of prostate cancer (PCa) to achieve good local control and low rectal toxicity. As rectal gas and r...

    Authors: Christian Schaefer, Constantinos Zamboglou, Natalja Volegova-Neher, Carmen Martini, Nils Henrik Nicolay, Nina-Sophie Schmidt-Hegemann, Paul Rogowski, Minglun Li, Claus Belka, Arndt-Christian Müller, Anca-Ligia Grosu and Thomas Brunner

    Citation: Radiation Oncology 2020 15:27

    Content type: Research

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  37. Single session radiosurgery represents a widely accepted treatment for intracranial meningiomas. However, this approach could involve a high risk of treatment-related complications when applied to large volume...

    Authors: V. Pinzi, M. Marchetti, E. De Martin, V. Cuccarini, I. Tramacere, F. Ghielmetti, M. L. Fumagalli, C. Iezzoni and L. Fariselli

    Citation: Radiation Oncology 2020 15:26

    Content type: Study protocol

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  38. To evaluate the long-term efficacy and toxicity of radiation therapy in patients with Stage IE primary ocular adnexal mucosa-associated lymphoid tissue lymphoma.

    Authors: Masanari Niwa, Satoshi Ishikura, Kotoha Tatekawa, Natsuko Takama, Akifumi Miyakawa, Toshinobu Kubota, Eriko Kato and Yuta Shibamoto

    Citation: Radiation Oncology 2020 15:25

    Content type: Research

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  39. Stereotactic Ablative Radiotherapy (SABR) is an effective treatment that improves local control for many tumours. However, the role of SABR in gynecological cancers (GYN) has not been well-established. We hypo...

    Authors: E. Leung, A. Gladwish, A. Sahgal, S. S. Lo, C. A. Kunos, R. M. Lanciano, C. A. Mantz, M. Guckenberger, T. M. Zagar, N. A. Mayr, A. R. Chang, S. Jorcano, T. Biswas, A. Pontoriero and K. V. Albuquerque

    Citation: Radiation Oncology 2020 15:24

    Content type: Research

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  40. Curative intent therapy of stage II NSCLC may include surgical resection or definitive radiotherapy. Primary management with surgery or radiotherapy may be influenced by patient and disease characteristics. We...

    Authors: Sara Moore, Bonnie Leung, Jonn Wu and Cheryl Ho

    Citation: Radiation Oncology 2020 15:23

    Content type: Research

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  41. To ascertain the dosimetric performance of a new delivery system (the Halcyon system, H) equipped with dual-layer stacked multi-leaf collimator (MLC) for risk-adapted targets in cervix uteri cancer patients co...

    Authors: S. Panda, J. Swamidas, S. Chopra, A. Mangaj, A. Fogliata, P. Kupelian, J. P. Agarwal and L. Cozzi

    Citation: Radiation Oncology 2020 15:22

    Content type: Research

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  42. To explore the dosimetric improvement, delivery efficiency, and plan robustness for bilateral head and neck cancer (HNC) treatment utilizing a novel proton therapy technique – the spot-scanning proton arc (SPA...

    Authors: Gang Liu, Xiaoqiang Li, An Qin, Weili Zheng, Di Yan, Sheng Zhang, Craig Stevens, Peyman Kabolizadeh and Xuanfeng Ding

    Citation: Radiation Oncology 2020 15:21

    Content type: Research

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  43. There is a lack of data on the biologically effective dose and the efficacy of stereotactic body radiotherapy in hepatocellular carcinoma patients, and this study was conducted to explore the relation between ...

    Authors: Jing Sun, Aimin Zhang, Wengang Li, Quan Wang, Dong Li, Dan Zhang and Xuezhang Duan

    Citation: Radiation Oncology 2020 15:20

    Content type: Study protocol

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  44. Despite aggressive treatment regimens comprising surgery and radiochemotherapy, glioblastoma (GBM) remains a cancer entity with very poor prognosis. The development of novel, combined modality approaches neces...

    Authors: Benjamin Stegen, Alexander Nieto, Valerie Albrecht, Jessica Maas, Michael Orth, Klement Neumaier, Sabine Reinhardt, Moritz Weick-Kleemann, Wilfried Goetz, Merle Reinhart, Katia Parodi, Claus Belka, Maximilian Niyazi and Kirsten Lauber

    Citation: Radiation Oncology 2020 15:19

    Content type: Research

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  45. Distant Metastases from Head and Neck Squamous cell carcinomas are uncommon (9–11%) and they are usually found in the lung and less frequently in the liver, kidney and adrenals.

    Authors: Agostino Cristaudo, Antonio Stefanelli, Stefano Ursino, Durim Delishaj, Davide Baldaccini, Alessandra Gonnelli and Fabiola Paiar

    Citation: Radiation Oncology 2020 15:18

    Content type: Case report

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  46. To compare the efficacy and toxicity of hypofractionated radiotherapy versus conventional fractionated radiotherapy in postmastectomy breast cancer using meta-analysis.

    Authors: Lei Liu, Yongqiang Yang, Qi Guo, Bixin Ren, Qiliang Peng, Li Zou, Yaqun Zhu and Ye Tian

    Citation: Radiation Oncology 2020 15:17

    Content type: Review

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  47. The benefit of adjuvant radiotherapy (ART) for extrahepatic cholangiocarcinoma (EHCC) and gallbladder carcinoma (GBC) is unclear, with conflicting results from nonrandomized studies. We reported a meta-analysi...

    Authors: Bixin Ren, Qi Guo, Yongqiang Yang, Lei Liu, Shaohua Wei, Wei Chen and Ye Tian

    Citation: Radiation Oncology 2020 15:15

    Content type: Review

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  48. Limited stage small cell lung cancer (LS-SCLC) has a poor prognosis. Additional prognostic markers are needed for risk-stratification and treatment intensification. This study compares quantitative CT-based vo...

    Authors: Sophia C. Kamran, Thibaud Coroller, Nastaran Milani, Vishesh Agrawal, Elizabeth H. Baldini, Aileen B. Chen, Bruce E. Johnson, David Kozono, Idalid Franco, Nitish Chopra, Roman Zeleznik, Hugo J. W. L. Aerts and Raymond Mak

    Citation: Radiation Oncology 2020 15:14

    Content type: Research

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  49. To compare target coverage and dose to the organs at risk in two approaches to rectal cancer: a clinically implemented adaptive radiotherapy (ART) strategy using plan selection, and a non-adaptive (non-ART) st...

    Authors: R. de Jong, J. Visser, K. F. Crama, N. van Wieringen, J. Wiersma, E. D. Geijsen and A. Bel

    Citation: Radiation Oncology 2020 15:13

    Content type: Research

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  50. To investigate the role of intensity modulated proton therapy (IMPT) compared to volumetric modulated arc therapy (VMAT) for advanced supradiaphragmatic Hodgkin’s lymphoma (HL) in young female patients by asse...

    Authors: Marta Scorsetti, Luca Cozzi, Pierina Navarria, Antonella Fogliata, Alexia Rossi, Davide Franceschini, Fiorenza De Rose, Ciro Franzese, Carmelo Carlo-Stella and Armando Santoro

    Citation: Radiation Oncology 2020 15:12

    Content type: Research

    Published on:

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Radiation Oncology

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