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  1. To analyze patterns of failure in patients with LA-NSCLC who received definitive chemoradiotherapy (CRT) and to build a nomogram for predicting the failure patterns in this population of patients.

    Authors: Xueru Zhu, Runping Hou, Xiaoyang Li, Chang Jiang, Wuyan Xia and Xiaolong Fu

    Citation: Radiation Oncology 2020 15:43

    Content type: Research

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  2. Although whole brain radiation therapy (WBRT) provides palliation and prophylaxis, reduces local recurrence probability and improves overall survival, it is evident that WBRT is associated with neurocognitive ...

    Authors: Adams Hei Long Yuen, Po Man Wu, Alex Kai Leung Li and Philip Chung Yin Mak

    Citation: Radiation Oncology 2020 15:42

    Content type: Research

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  3. The STAR-TReC trial is an international multi-center, randomized, phase II study assessing the feasibility of short-course radiotherapy or long-course chemoradiotherapy as an alternative to total mesorectal ex...

    Authors: Roy P. J. van den Ende, Femke P. Peters, Ernst Harderwijk, Heidi Rütten, Liza Bouwmans, Maaike Berbee, Richard A. M. Canters, Georgiana Stoian, Kim Compagner, Tom Rozema, Mariska de Smet, Martijn P. W. Intven, Rob H. N. Tijssen, Jacqueline Theuws, Paul van Haaren, Baukelien van Triest…

    Citation: Radiation Oncology 2020 15:41

    Content type: Research

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  4. On the elastic profiles of human teeth after radiotherapy for head and neck cancers, generation of dental complications, which may bring several side effects preventing the quality of life, has not well clarif...

    Authors: Irem Demirkan, Gokhan Yaprak, Cemile Ceylan, Emriye Algul, Ceyda Ozcakir Tomruk, Bukem Bilen and Mehmet Burcin Unlu

    Citation: Radiation Oncology 2020 15:38

    Content type: Research

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  5. There is limited data on the use of targeted or immunotherapy (TT/IT) in combination with single fraction stereotactic radiosurgery (SRS) in patients with melanoma brain metastasis (MBM). Therefore, we analyze...

    Authors: Indrawati Hadi, Olarn Roengvoraphoj, Raphael Bodensohn, Jan Hofmaier, Maximilian Niyazi, Claus Belka and Silke Birgit Nachbichler

    Citation: Radiation Oncology 2020 15:37

    Content type: Research

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  6. The development of radiation pneumonitis (RP) after Stereotactic Body Radiotherapy (SBRT) is known to be associated with many different factors, although historical analyses of RP have commonly utilized hetero...

    Authors: Jeffrey M. Ryckman, Michael Baine, Joseph Carmicheal, Ferdinand Osayande, Richard Sleightholm, Kaeli Samson, Dandan Zheng, Weining Zhen, Chi Lin and Chi Zhang

    Citation: Radiation Oncology 2020 15:33

    Content type: Research

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  7. In this study we have evaluated the accuracy of automatic, deformable structure propagation from planning CT and MR scans for daily online plan adaptation for MR linac (MRL) treatment, which is an important el...

    Authors: Rasmus Lübeck Christiansen, Lars Dysager, Anders Smedegaard Bertelsen, Olfred Hansen, Carsten Brink and Uffe Bernchou

    Citation: Radiation Oncology 2020 15:32

    Content type: Research

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  8. Head-and-neck squamous cell carcinoma (HNSCC) is one of the most common malignancies globally, and the number of elderly patients diagnosed with HNSCC is increasing. However, as elderly HNSCC patients are unde...

    Authors: Erik Haehl, Alexander Rühle, Hélène David, Tobias Kalckreuth, Tanja Sprave, Raluca Stoian, Christoph Becker, Andreas Knopf, Anca-Ligia Grosu and Nils H. Nicolay

    Citation: Radiation Oncology 2020 15:31

    Content type: Research

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  9. Local ablative treatment strategies are frequently offered to patients diagnosed with oligometastatic disease. Stereotactic body radiotherapy (SBRT), as ablative treatment option, is well established for lung ...

    Authors: Laila König, Matthias F. Häfner, Sonja Katayama, Stefan A. Koerber, Eric Tonndorf-Martini, Denise Bernhardt, Bastian von Nettelbladt, Fabian Weykamp, Philipp Hoegen, Sebastian Klüter, Matthew S. Susko, Jürgen Debus and Juliane Hörner-Rieber

    Citation: Radiation Oncology 2020 15:30

    Content type: Research

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  10. Following publication of the original article [1], we have been notified that the below text parts of the Discussion chapter should be changed.

    Authors: Kilian-Simon Baumann, Veronika Flatten, Uli Weber, Stefan Lautenschläger, Fabian Eberle, Klemens Zink and Rita Engenhart-Cabillic

    Citation: Radiation Oncology 2020 15:29

    Content type: Correction

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    The original article was published in Radiation Oncology 2019 14:183

  11. Colorectal cancer treatment requires a complex, multidisciplinary approach. Because of the potential variability, monitoring through clinical audits is advisable. This study assesses the effects of a quality i...

    Authors: M. G. Torras, E. Canals, C. Muñoz-Montplet, A. Vidal, D. Jurado, A. Eraso, S. Villà, M. Caro, J. Molero, M. Macià, M. Puigdemont, E. González-Muñoz, A. López, F. Guedea and J. M. Borras

    Citation: Radiation Oncology 2020 15:28

    Content type: Research

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  12. Small inter- and intrafractional prostate motion was shown to be a prerequisite for precise radiotherapy (RT) of prostate cancer (PCa) to achieve good local control and low rectal toxicity. As rectal gas and r...

    Authors: Christian Schaefer, Constantinos Zamboglou, Natalja Volegova-Neher, Carmen Martini, Nils Henrik Nicolay, Nina-Sophie Schmidt-Hegemann, Paul Rogowski, Minglun Li, Claus Belka, Arndt-Christian Müller, Anca-Ligia Grosu and Thomas Brunner

    Citation: Radiation Oncology 2020 15:27

    Content type: Research

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  13. Single session radiosurgery represents a widely accepted treatment for intracranial meningiomas. However, this approach could involve a high risk of treatment-related complications when applied to large volume...

    Authors: V. Pinzi, M. Marchetti, E. De Martin, V. Cuccarini, I. Tramacere, F. Ghielmetti, M. L. Fumagalli, C. Iezzoni and L. Fariselli

    Citation: Radiation Oncology 2020 15:26

    Content type: Study protocol

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  14. To evaluate the long-term efficacy and toxicity of radiation therapy in patients with Stage IE primary ocular adnexal mucosa-associated lymphoid tissue lymphoma.

    Authors: Masanari Niwa, Satoshi Ishikura, Kotoha Tatekawa, Natsuko Takama, Akifumi Miyakawa, Toshinobu Kubota, Eriko Kato and Yuta Shibamoto

    Citation: Radiation Oncology 2020 15:25

    Content type: Research

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  15. Stereotactic Ablative Radiotherapy (SABR) is an effective treatment that improves local control for many tumours. However, the role of SABR in gynecological cancers (GYN) has not been well-established. We hypo...

    Authors: E. Leung, A. Gladwish, A. Sahgal, S. S. Lo, C. A. Kunos, R. M. Lanciano, C. A. Mantz, M. Guckenberger, T. M. Zagar, N. A. Mayr, A. R. Chang, S. Jorcano, T. Biswas, A. Pontoriero and K. V. Albuquerque

    Citation: Radiation Oncology 2020 15:24

    Content type: Research

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  16. Curative intent therapy of stage II NSCLC may include surgical resection or definitive radiotherapy. Primary management with surgery or radiotherapy may be influenced by patient and disease characteristics. We...

    Authors: Sara Moore, Bonnie Leung, Jonn Wu and Cheryl Ho

    Citation: Radiation Oncology 2020 15:23

    Content type: Research

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  17. To ascertain the dosimetric performance of a new delivery system (the Halcyon system, H) equipped with dual-layer stacked multi-leaf collimator (MLC) for risk-adapted targets in cervix uteri cancer patients co...

    Authors: S. Panda, J. Swamidas, S. Chopra, A. Mangaj, A. Fogliata, P. Kupelian, J. P. Agarwal and L. Cozzi

    Citation: Radiation Oncology 2020 15:22

    Content type: Research

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  18. To explore the dosimetric improvement, delivery efficiency, and plan robustness for bilateral head and neck cancer (HNC) treatment utilizing a novel proton therapy technique – the spot-scanning proton arc (SPA...

    Authors: Gang Liu, Xiaoqiang Li, An Qin, Weili Zheng, Di Yan, Sheng Zhang, Craig Stevens, Peyman Kabolizadeh and Xuanfeng Ding

    Citation: Radiation Oncology 2020 15:21

    Content type: Research

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  19. There is a lack of data on the biologically effective dose and the efficacy of stereotactic body radiotherapy in hepatocellular carcinoma patients, and this study was conducted to explore the relation between ...

    Authors: Jing Sun, Aimin Zhang, Wengang Li, Quan Wang, Dong Li, Dan Zhang and Xuezhang Duan

    Citation: Radiation Oncology 2020 15:20

    Content type: Study protocol

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  20. Despite aggressive treatment regimens comprising surgery and radiochemotherapy, glioblastoma (GBM) remains a cancer entity with very poor prognosis. The development of novel, combined modality approaches neces...

    Authors: Benjamin Stegen, Alexander Nieto, Valerie Albrecht, Jessica Maas, Michael Orth, Klement Neumaier, Sabine Reinhardt, Moritz Weick-Kleemann, Wilfried Goetz, Merle Reinhart, Katia Parodi, Claus Belka, Maximilian Niyazi and Kirsten Lauber

    Citation: Radiation Oncology 2020 15:19

    Content type: Research

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  21. Distant Metastases from Head and Neck Squamous cell carcinomas are uncommon (9–11%) and they are usually found in the lung and less frequently in the liver, kidney and adrenals.

    Authors: Agostino Cristaudo, Antonio Stefanelli, Stefano Ursino, Durim Delishaj, Davide Baldaccini, Alessandra Gonnelli and Fabiola Paiar

    Citation: Radiation Oncology 2020 15:18

    Content type: Case report

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  22. To compare the efficacy and toxicity of hypofractionated radiotherapy versus conventional fractionated radiotherapy in postmastectomy breast cancer using meta-analysis.

    Authors: Lei Liu, Yongqiang Yang, Qi Guo, Bixin Ren, Qiliang Peng, Li Zou, Yaqun Zhu and Ye Tian

    Citation: Radiation Oncology 2020 15:17

    Content type: Review

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  23. The benefit of adjuvant radiotherapy (ART) for extrahepatic cholangiocarcinoma (EHCC) and gallbladder carcinoma (GBC) is unclear, with conflicting results from nonrandomized studies. We reported a meta-analysi...

    Authors: Bixin Ren, Qi Guo, Yongqiang Yang, Lei Liu, Shaohua Wei, Wei Chen and Ye Tian

    Citation: Radiation Oncology 2020 15:15

    Content type: Review

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  24. Limited stage small cell lung cancer (LS-SCLC) has a poor prognosis. Additional prognostic markers are needed for risk-stratification and treatment intensification. This study compares quantitative CT-based vo...

    Authors: Sophia C. Kamran, Thibaud Coroller, Nastaran Milani, Vishesh Agrawal, Elizabeth H. Baldini, Aileen B. Chen, Bruce E. Johnson, David Kozono, Idalid Franco, Nitish Chopra, Roman Zeleznik, Hugo J. W. L. Aerts and Raymond Mak

    Citation: Radiation Oncology 2020 15:14

    Content type: Research

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  25. To compare target coverage and dose to the organs at risk in two approaches to rectal cancer: a clinically implemented adaptive radiotherapy (ART) strategy using plan selection, and a non-adaptive (non-ART) st...

    Authors: R. de Jong, J. Visser, K. F. Crama, N. van Wieringen, J. Wiersma, E. D. Geijsen and A. Bel

    Citation: Radiation Oncology 2020 15:13

    Content type: Research

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  26. To investigate the role of intensity modulated proton therapy (IMPT) compared to volumetric modulated arc therapy (VMAT) for advanced supradiaphragmatic Hodgkin’s lymphoma (HL) in young female patients by asse...

    Authors: Marta Scorsetti, Luca Cozzi, Pierina Navarria, Antonella Fogliata, Alexia Rossi, Davide Franceschini, Fiorenza De Rose, Ciro Franzese, Carmelo Carlo-Stella and Armando Santoro

    Citation: Radiation Oncology 2020 15:12

    Content type: Research

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  27. Neoadjuvant external-beam radiotherapy (EBRT) with concomitant chemotherapy is the current standard-of-care for locally-advanced rectal cancer. Intraoperative radiotherapy (IORT) is to date only recommended fo...

    Authors: Sergey Potemin, Jens Kübler, Ivan Uvarov, Frederik Wenz and Frank Giordano

    Citation: Radiation Oncology 2020 15:11

    Content type: Research

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  28. Homeodomain-interacting protein kinase 2 (HIPK2) has increasingly drawn attention as recent researches demonstrated its unique role in the regulation of multiple fundamental processes such as apoptosis, prolifera...

    Authors: Yang Tang, Li Yang, Wan Qin, Min’ Xiao Yi, Bo Liu and Xiang’Lin Yuan

    Citation: Radiation Oncology 2020 15:9

    Content type: Research

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  29. Definitive chemoradiotherapy (dCRT) is a standard treatment for patients with locally advanced head and neck cancer. There is a clinical need for a stratification of this prognostically heterogeneous group of ...

    Authors: Lars Schüttrumpf, Sebastian Marschner, Katrin Scheu, Julia Hess, Sibylle Rietzler, Axel Walch, Philipp Baumeister, Thomas Kirchner, Ute Ganswindt, Horst Zitzelsberger, Claus Belka and Cornelius Maihoefer

    Citation: Radiation Oncology 2020 15:7

    Content type: Research

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  30. To determine the relative biological effectiveness (RBE) and α/β-values after fractionated carbon ion irradiations of the rat spinal cord with varying linear energy transfer (LET) to benchmark RBE-model calculati...

    Authors: Maria Saager, Christin Glowa, Peter Peschke, Stephan Brons, Rebecca Grün, Michael Scholz, Jürgen Debus and Christian P. Karger

    Citation: Radiation Oncology 2020 15:6

    Content type: Research

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  31. mmune checkpoint inhibition (CPI) has an increasing impact in the multimodal treatment of locally advanced non-small cell lung cancer (LA-NSCLC). Increasing evidence suggests treatment outcome depending on tum...

    Authors: Kathrin Gennen, Lukas Käsmann, Julian Taugner, Chukwuka Eze, Monika Karin, Olarn Roengvoraphoj, Jens Neumann, Amanda Tufman, Michael Orth, Simone Reu, Claus Belka and Farkhad Manapov

    Citation: Radiation Oncology 2020 15:5

    Content type: Research

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  32. Intra-and inter-tumoral heterogeneity in growth dynamics and vascularity influence tumor response to radiation therapy. Quantitative imaging techniques capture these dynamics non-invasively, and these data can...

    Authors: David A. Hormuth II, Angela M. Jarrett and Thomas E. Yankeelov

    Citation: Radiation Oncology 2020 15:4

    Content type: Research

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  33. The development of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) has dramatically improved the prognosis of patients with EGFR-mutant non-small-cell lung cancer (NSCLC). The purpose o...

    Authors: Lihao Zhao, Xiaona Cai, Didi Chen, Xuxue Ye, Mengdan Gao, Lihuai Lu, Huafang Su, Meng Su, Meng Hou and Congying Xie

    Citation: Radiation Oncology 2019 15:3

    Content type: Research

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  34. Individual radiosensitivity is influencing the outcome of radiation therapy. A general ex vivo testing is very work-intensive. It is of interest to see if a significant prediction concerning the sensitivity ca...

    Authors: Theresa Mayo, Marlen Haderlein, Barbara Schuster, Anna Wiesmüller, Christian Hummel, Maximilian Bachl, Manfred Schmidt, Rainer Fietkau and Luitpold Distel

    Citation: Radiation Oncology 2019 15:2

    Content type: Research

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  35. Iodine seed implant brachytherapy is indicated for low risk and selected favorable intermediate risk prostate cancers. A percentage of positive biopsies > 50% is usually considered as a contra-indication, and ...

    Authors: Claire Meynard, Andres Huertas, Charles Dariane, Sandra Toublanc, Quentin Dubourg, Saik Urien, Marc-Olivier Timsit, Arnaud Méjean, Nicolas Thiounn and Philippe Giraud

    Citation: Radiation Oncology 2019 15:1

    Content type: Research

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  36. Volumetric Modulated Arc Therapy (VMAT) techniques have recently been implemented in clinical practice for total-body irradiation (TBI). To date, most techniques still use special couches, translational tables...

    Authors: Christoph Losert, Roel Shpani, Robert Kießling, Philipp Freislederer, Minglun Li, Franziska Walter, Maximilian Niyazi, Michael Reiner, Claus Belka and Stefanie Corradini

    Citation: Radiation Oncology 2019 14:244

    Content type: Research

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  37. Existing pencil beam analytical (PBA) algorithms for proton therapy treatment planning are not ideal for sites with heterogeneous tissue density and do not account for the spatial variations in proton relative...

    Authors: Yolanda D. Tseng, Shadonna M. Maes, Gregory Kicska, Patricia Sponsellor, Erik Traneus, Tony Wong, Robert D. Stewart and Jatinder Saini

    Citation: Radiation Oncology 2019 14:243

    Content type: Research

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  38. Cardiac activity could impact the accuracy of dose assessment for the heart, pericardium and left ventricular myocardium (LVM). The purpose of this study was to explore whether it is possible to perform dose a...

    Authors: Ying Tong, Guanzhong Gong, Ming Su and Yong Yin

    Citation: Radiation Oncology 2019 14:242

    Content type: Research

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  39. The effectiveness of proton beam therapy (PBT) as initial treatment for patients with unresectable intrahepatic cholangiocarcinoma (ICC) is unclear, particularly as related to ICC histological subtypes. We per...

    Authors: Shosei Shimizu, Toshiyuki Okumura, Yoshiko Oshiro, Nobuyoshi Fukumitsu, Kuniaki Fukuda, Kazunori Ishige, Naoyuki Hasegawa, Haruko Numajiri, Keiko Murofushi, Kayoko Ohnishi, Masashi Mizumoto, Tetsuo Nonaka, Hitoshi Ishikawa and Hideyuki Sakurai

    Citation: Radiation Oncology 2019 14:241

    Content type: Research

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  40. As optic nerve sheath meningiomas (ONSM) are rare, there are no prospective studies. Our retrospective analysis focusses on a cohort of patients with uniform disease characteristics all treated with the same r...

    Authors: Franziska Eckert, Kerstin Clasen, Carina Kelbsch, Felix Tonagel, Benjamin Bender, Ghazaleh Tabatabai, Daniel Zips, Daniela Thorwarth, Bettina Frey, Gerd Becker, Helmut Wilhelm and Frank Paulsen

    Citation: Radiation Oncology 2019 14:240

    Content type: Research

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  41. conjunctival melanomas have high local relapse rates. Oncologic and visual outcomes can be improved with proton therapy and no-touch surgery.

    Authors: Juliette Thariat, Julia Salleron, Celia Maschi, Edouard Fevrier, Sandra Lassalle, Lauris Gastaud, Stephanie Baillif, Audrey Claren, Florent Baumard, Joel Herault and Jean Pierre Caujolle

    Citation: Radiation Oncology 2019 14:239

    Content type: Research

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  42. Helical tomotherapy has been applied to total marrow irradiation (HT-TMI). Our objective was to apply failure mode and effects analysis (FMEA) two times separated by 1 year to evaluate and improve the safety o...

    Authors: Jiuling Shen, Xiaoyong Wang, Di Deng, Jian Gong, Kang Tan, Hongli Zhao, Zhirong Bao, Jinping Xiao, An Liu, Yunfeng Zhou, Hui Liu and Conghua Xie

    Citation: Radiation Oncology 2019 14:238

    Content type: Research

    Published on:

  43. In this study, a novel pelvic phantom was developed and used to assess the visibility and presence of artefacts from different types of commercial fiducial markers (FMs) on multi-modality imaging relevant to p...

    Authors: Sarah O. S. Osman, Emily Russell, Raymond B. King, Karen Crowther, Suneil Jain, Cormac McGrath, Alan R. Hounsell, Kevin M. Prise and Conor K. McGarry

    Citation: Radiation Oncology 2019 14:237

    Content type: Research

    Published on:

  44. Some studies have demonstrated that concurrent chemo-radiotherapy is an effective salvage treatment for isolated para-aortic lymph node (PALN) recurrence.

    Authors: Hikaru Kubota, Kayoko Tsujino, Nor Shazrina Sulaiman, Shuhei Sekii, Yoko Matsumoto, Yosuke Ota, Toshinori Soejima, Satoshi Yamaguchi and Ryohei Sasaki

    Citation: Radiation Oncology 2019 14:236

    Content type: Research

    Published on:

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