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Radiation Oncology


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  1. Content type: Research

    Proton beam therapy is promising for the treatment of head and neck cancer (HNC), but it is sensitive to uncertainties in patient positioning and particle range. Studies have shown that the planning target vol...

    Authors: Macarena Cubillos-Mesías, Michael Baumann, Esther G. C. Troost, Fabian Lohaus, Steffen Löck, Christian Richter and Kristin Stützer

    Citation: Radiation Oncology 2017 12:190

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  2. Content type: Research

    Intrafractional motion can be a substantial uncertainty in precision radiotherapy. Conventionally, the target volume is expanded to account for the motion. Couch-tracking is an alternative, where the patient i...

    Authors: Alexander Jöhl, Marta Bogowicz, Stefanie Ehrbar, Matthias Guckenberger, Stephan Klöck, Mirko Meboldt, Oliver Riesterer, Melanie Zeilinger, Marianne Schmid Daners and Stephanie Tanadini-Lang

    Citation: Radiation Oncology 2017 12:189

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  3. Content type: Study protocol

    The prognosis for patients with cervical or endometrial cancer has improved over the last decades. Thus, reducing therapy-related toxicity and impact on quality of life have become more and more important. Wit...

    Authors: N. Arians, K. Lindel, J. Krisam, K. Herfarth, D. Krug, S. Akbaba, J. Oelmann-Avendano and J. Debus

    Citation: Radiation Oncology 2017 12:188

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  4. Content type: Research

    This work explores how the choice of prescription isodose line (IDL) affects the dose gradient, target coverage, and treatment time for Gamma Knife radiosurgery when a smaller shot is encompassed within a larg...

    Authors: Perry B. Johnson, Maria I. Monterroso, Fei Yang and Eric Mellon

    Citation: Radiation Oncology 2017 12:187

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  5. Content type: Correction

    In the original publication [1] the name of author Jeremy M. Aymard was spelled wrong. The original article was updated to rectify this error.

    Authors: Salman A. Eraj, Mona K. Jomaa, Crosby D. Rock, Abdallah S. R. Mohamed, Blaine D. Smith, Joshua B. Smith, Theodora Browne, Luke C. Cooksey, Bowman Williams, Brandi Temple, Kathryn E. Preston, Jeremy M. Aymard, Neil D. Gross, Randal S. Weber, Amy C. Hessel, Renata Ferrarotto…

    Citation: Radiation Oncology 2017 12:186

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    The original article was published in Radiation Oncology 2017 12:150

  6. Content type: Research

    To investigate the advantage of concurrent chemotherapy with postoperative radiotherapy (RT) of oral squamous cell carcinoma (OSCC) in patients with three or more minor risk factors.

    Authors: Kang-Hsing Fan, Yen-Chao Chen, Chien-Yu Lin, Chung-Jan Kang, Li-Yu Lee, Shiang-Fu Huang, Chun-Ta Liao, Shu-Hang Ng, Hung-Ming Wang and Joseph Tung-Chieh Chang

    Citation: Radiation Oncology 2017 12:184

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  7. Content type: Research

    The skin is considered a critical organ at risk in carbon ion radiotherapy (CIRT) for locally advanced malignant bone and soft tissue tumors (MBSTs). The predictive factors for acute skin reactions after CIRT ...

    Authors: Yosuke Takakusagi, Jun-ichi Saitoh, Hiroki Kiyohara, Takahiro Oike, Shin-ei Noda, Tatsuya Ohno and Takashi Nakano

    Citation: Radiation Oncology 2017 12:185

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  8. Content type: Study protocol

    Pancreatic cancer has a dismal prognosis with 5-year overall survival rate of around 5%. Although surgery is still the best option in operable cases, majority of the patients who present in locally advanced st...

    Authors: Niloy Ranjan Datta, Bernhard Pestalozzi, Pierre-Alain Clavien, Alexander Siebenhüner, Emsad Puric, Shaka Khan, Christoph Mamot, Oliver Riesterer, Jürg Knuchel, Cäcilia Sophie Reiner and Stephan Bodis

    Citation: Radiation Oncology 2017 12:183

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  9. Content type: Research

    To investigate the feasibility of using dual-energy CT (DECT) for tissue segmentation and kilovolt (kV) dose calculations in pre-clinical studies and assess potential dose calculation accuracy gain.

    Authors: Ana Vaniqui, Lotte E. J. R. Schyns, Isabel P. Almeida, Brent van der Heyden, Stefan J. van Hoof and Frank Verhaegen

    Citation: Radiation Oncology 2017 12:181

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  10. Content type: Research

    Neoadjuvant chemoradiation (nCRT) is the treatment of choice for patients with locally advanced squamous cell carcinoma of the esophagus (SCC). Today radiation oncologists can choose between two different ther...

    Authors: Stefan Münch, Steffi U. Pigorsch, Marcus Feith, Julia Slotta-Huspenina, Wilko Weichert, Helmut Friess, Stephanie E. Combs and Daniel Habermehl

    Citation: Radiation Oncology 2017 12:182

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  11. Content type: Research

    SCOPE 1 was the first UK based multi-centre trial involving radiotherapy of the oesophagus. A comprehensive radiotherapy trials quality assurance programme was launched with two main aims:


    Authors: Lucy Wills, Rhydian Maggs, Geraint Lewis, Gareth Jones, Lisette Nixon, John Staffurth and Tom Crosby

    Citation: Radiation Oncology 2017 12:179

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  12. Content type: Research

    The aim of this study was to report outcomes and late toxicity following hypofractionated accelerated radiotherapy for T2 glottic cancers. We highlight the importance of hypofractionated treatments with shorte...

    Authors: Lynne M. Dixon, Catriona M. Douglas, Shazril Imran Shaukat, Kate Garcez, Lip Wai Lee, Andrew J. Sykes, David Thomson and Nicholas J. Slevin

    Citation: Radiation Oncology 2017 12:178

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  13. Content type: Research

    We compared the functional outcome and influential factors of two standard treatment modalities for central cerebral metastases: electrophysiological-controlled microsurgical resection (MSR) and stereotactic r...

    Authors: Bogdan Pintea, Brigitta Baumert, Thomas Mehari Kinfe, Konstantinos Gousias, Yaroslav Parpaley and Jan Patrick Boström

    Citation: Radiation Oncology 2017 12:177

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  14. Content type: Research

    To determine the potential role of 68Ga-PSMA positron emission tomography/computed tomography (PET/CT) in radiotherapy (RT) planning for prostate cancer (PCa).

    Authors: Nina-Sophie Schmidt-Hegemann, Wolfgang Peter Fendler, Alexander Buchner, Christian Stief, Paul Rogowski, Maximilian Niyazi, Chukwuka Eze, Minglun Li, Peter Bartenstein, Claus Belka and Ute Ganswindt

    Citation: Radiation Oncology 2017 12:176

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  15. Content type: Research

    Radiotherapy for pancreatic cancer has two major challenges: (I) the tumor is adjacent to several critical organs and, (II) the mobility of both, the tumor and its surrounding organs at risk (OARs). A treatmen...

    Authors: Konstantina Karava, Stefanie Ehrbar, Oliver Riesterer, Johannes Roesch, Stefan Glatz, Stephan Klöck, Matthias Guckenberger and Stephanie Tanadini-Lang

    Citation: Radiation Oncology 2017 12:175

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  16. Content type: Research

    To summarize the research activities of the “clinical research group heavy ion therapy”, funded by the German Research Foundation (DFG, KFO 214), on the impact of intrinsic tumor characteristics (grading, hypo...

    Authors: Christin Glowa, Peter Peschke, Stephan Brons, Oliver C. Neels, Klaus Kopka, Jürgen Debus and Christian P. Karger

    Citation: Radiation Oncology 2017 12:174

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  17. Content type: Correction

    In the original publication [1] figure legends 2 and 4 have been swapped. The original article was updated to rectify this error.

    Authors: J. Krayenbuehl, M. Di Martino, M. Guckenberger and N. Andratschke

    Citation: Radiation Oncology 2017 12:173

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    The original article was published in Radiation Oncology 2017 12:161

  18. Content type: Research

    Normal lung tissue tolerance constitutes a limiting factor in delivering the required dose of radiotherapy to cure thoracic and chest wall malignancies. Radiation-induced lung fibrosis (RILF) is considered a c...

    Authors: Cheng Zhou, Bleddyn Jones, Mahmoud Moustafa, Christian Schwager, Julia Bauer, Bing Yang, Liji Cao, Min Jia, Andrea Mairani, Ming Chen, Longhua Chen, Juergen Debus and Amir Abdollahi

    Citation: Radiation Oncology 2017 12:172

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  19. Content type: Research

    The purpose of this study was to demonstrate the feasibility of physician driven planning in intensity modulated radiotherapy (IMRT) with a multicriteria optimization (MCO) treatment planning system and templa...

    Authors: Birgit S. Müller, Helen A. Shih, Jason A. Efstathiou, Thomas Bortfeld and David Craft

    Citation: Radiation Oncology 2017 12:168

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  20. Content type: Research

    Radiation pneumonitis (RP) has been a challenging obstacle in treating stage III lung cancer patients. Beam angle optimization (BAO) technique for Tomotherapy was developed to reduce the normal lung dose for s...

    Authors: Chae-Seon Hong, Sang Gyu Ju, Yong Chan Ahn, Gyu Sang Yoo, Jae Myoung Noh, Dongryul Oh, Kwangzoo Chung, Hongryull Pyo and Kwanghyun Jo

    Citation: Radiation Oncology 2017 12:167

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  21. Content type: Review

    Scanned ion beam therapy has special demands for treatment of intra-fractionally moving tumors such as lesions in lung or liver. Interplay effects between beam and organ motion can in those settings lead to un...

    Authors: Christoph Bert and Klaus Herfarth

    Citation: Radiation Oncology 2017 12:170

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  22. Content type: Research

    For irradiation treatment planning of meningiomas the use of PET-scans is well established. The most frequently used tracers are either based on amino acids or the somatostatin receptor ligand DOTATOC. Since u...

    Authors: Jan Oliver Dittmar, Clemens Kratochwil, Anne Dittmar, Thomas Welzel, Daniel Habermehl, Stefan Rieken, Frederik L. Giesel, Uwe Haberkorn, Jürgen Debus and Stephanie E. Combs

    Citation: Radiation Oncology 2017 12:169

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  23. Content type: Research

    The “gold standard” approach for defining an internal target volume (ITV) is using 10 gross tumor volume (GTV) phases delineated over the course of one respiratory cycle. However, different sites have adopted ...

    Authors: Dennis J. Mohatt, John M. Keim, Mathew C. Greene, Ami Patel-Yadav, Jorge A. Gomez and Harish K. Malhotra

    Citation: Radiation Oncology 2017 12:166

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  24. Content type: Research

    Radiation pneumonitis (RP) is the most common subacute side effect after concurrent chemoradiotherapy (CRT) for locally advanced non-small cell lung cancer. Several clinical and dose-volume (DV) parameters are...

    Authors: Mohammed Alharbi, Stefan Janssen, Heiko Golpon, Michael Bremer and Christoph Henkenberens

    Citation: Radiation Oncology 2017 12:165

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