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  1. Content type: Research

    Postoperative (chemo) radiation improves tumor control and survival in high-risk patients with head and neck squamous cell carcinoma based on established risk factors. The clinical cooperation group “Personali...

    Authors: Cornelius Maihoefer, Lars Schüttrumpf, Corinna Macht, Ulrike Pflugradt, Julia Hess, Ludmila Schneider, Christine Woischke, Axel Walch, Philipp Baumeister, Thomas Kirchner, Horst Zitzelsberger, Claus Belka and Ute Ganswindt

    Citation: Radiation Oncology 2018 13:123

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  2. Content type: Research

    The benefits of proton therapy in the treatment of patients with Hodgkin lymphoma (HL) are controversially discussed. Therefore we compared intensitiy modulated proton therapy (IMPT) with intensity modulated r...

    Authors: Christian Baues, Simone Marnitz, Andreas Engert, Wolfgang Baus, Karolina Jablonska, Antonella Fogliata, Andrés Vásquez-Torres, Marta Scorsetti and Luca Cozzi

    Citation: Radiation Oncology 2018 13:122

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  3. Content type: Review

    The use of the Monte Carlo (MC) method in radiotherapy dosimetry has increased almost exponentially in the last decades. Its widespread use in the field has converted this computer simulation technique in a co...

    Authors: Pedro Andreo

    Citation: Radiation Oncology 2018 13:121

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  4. Content type: Research

    A new implementation has been made on CloudMC, a cloud-based platform presented in a previous work, in order to provide services for radiotherapy treatment verification by means of Monte Carlo in a fast, easy ...

    Authors: Hector Miras, Rubén Jiménez, Álvaro Perales, José Antonio Terrón, Alejandro Bertolet, Antonio Ortiz and José Macías

    Citation: Radiation Oncology 2018 13:99

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  5. Content type: Research

    Uncertainties associated with the delivery of treatment to moving organs might compromise the accuracy of treatment. This study explores the impact of intra-fractional anatomical changes in pancreatic patients...

    Authors: Vania Batista, Daniel Richter, Naved Chaudhri, Patrick Naumann, Klaus Herfarth and Oliver Jäkel

    Citation: Radiation Oncology 2018 13:120

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  6. Content type: Research

    Carbon-ion radiotherapy (C-ion RT) provides better dose distribution in cancer treatment compared to photons. Additionally, carbon-ion beams provide a higher biological effectiveness, and thus a higher tumor c...

    Authors: Noriyuki Okonogi, Mai Fukahori, Masaru Wakatsuki, Yu Ohkubo, Shingo Kato, Yuhei Miyasaka, Hiroshi Tsuji, Takashi Nakano and Tadashi Kamada

    Citation: Radiation Oncology 2018 13:119

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  7. Content type: Research

    The purpose was to retrospectively evaluate the effect of intensity-modulated radiotherapy (IMRT) on gastrointestinal (GI) toxicities and outcomes compared to three-dimensional conformal radiotherapy (3DCRT) f...

    Authors: Yoko Goto, Akira Nakamura, Ryo Ashida, Katsuyuki Sakanaka, Satoshi Itasaka, Keiko Shibuya, Shigemi Matsumoto, Masashi Kanai, Hiroyoshi Isoda, Toshihiko Masui, Yuzo Kodama, Kyoichi Takaori, Masahiro Hiraoka and Takashi Mizowaki

    Citation: Radiation Oncology 2018 13:118

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  8. Content type: Correction

    The original version of this article [1] unfortunately contained a mistake.

    Authors: Wen-zhao Sun, Dan-dan Zhang, Ying-lin Peng, Li Chen, De-hua Kang, Bin Wang and Xiao-wu Deng

    Citation: Radiation Oncology 2018 13:117

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    The original article was published in Radiation Oncology 2018 13:42

  9. Content type: Research

    Deep inspiration breath hold (DIBH) can be performed using different breathing maneuvers, such as DIBH with a thoracic breathing maneuver (T-DIBH) and DIBH with an abdominal breathing maneuver (A-DIBH). Dosime...

    Authors: Feng Zhao, Jiayan Shen, Zhongjie Lu, Yongbiao Luo, Guorong Yao, Luyi Bu, Jia Ge, Xin Yang, Lihua Ning and Senxiang Yan

    Citation: Radiation Oncology 2018 13:116

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  10. Content type: Case report

    Granular cell or Abrikossoff’s tumors are usually benign however rare malignant forms concern 1 to 3% of cases reported. Pelvic locations are exceptional.

    Authors: C. Marchand Crety, C. Garbar, G. Madelis, F. Guillemin, P. Soibinet Oudot, J. C. Eymard and S. Servagi Vernat

    Citation: Radiation Oncology 2018 13:115

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  11. Content type: Research

    This is a dosimetric comparative study intended to establish appropriate low-to-intermediate dose-constraints for the rectal wall (Rwall) in the context of a randomized phase-II trial on urethra-sparing stereotac...

    Authors: Angèle Dubouloz, Michel Rouzaud, Lev Tsvang, Wilko Verbakel, Mikko Björkqvist, Nadine Linthout, Joana Lencart, Juan María Pérez-Moreno, Zeynep Ozen, Lluís Escude, Thomas Zilli and Raymond Miralbell

    Citation: Radiation Oncology 2018 13:114

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  12. Content type: Research

    The goal of this study is to evaluate the status and future perspectives of clinical trials on positron emission tomography in prostate cancer for diagnostic or therapeutic as well as for surveillance purposes.

    Authors: Nikola Cihoric, Eugenia Vlaskou Badra, Alexandros Tsikkinis, Vikas Prasad, Stephanie Kroeze, Ivan Igrutinovic, Branislav Jeremic, Marcus Beck, Sebastian Zschaeck, Peter Wust and Pirus Ghadjar

    Citation: Radiation Oncology 2018 13:113

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  13. Content type: Research

    In intensity modulated radiation therapy (IMRT) quality assurance (QA), evaluation of QA result using a pass/non-pass strategy under an acceptance criterion often suffers from lack of information on how good t...

    Authors: Dong-Su Kim, Siyong Kim, Seong-Hee Kang, Tae-Ho Kim, So-Hyun Park, Kyeong-Hyeon Kim, Min-Seok Cho, Dong-Seok Shin, Yu-Yun Noh, Jin-Beom Chung and Tae Suk Suh

    Citation: Radiation Oncology 2018 13:112

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  14. Content type: Research

    We investigated the effectiveness of one education course to lower the severity of anxiety and depression symptoms among breast cancer (BC) patients during radiotherapy (RT).

    Authors: Zhensheng Li, Wenhui Geng, Junpu Yin and Jun Zhang

    Citation: Radiation Oncology 2018 13:111

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  15. Content type: Research

    The aim of the present study was to evaluate the influence of the applied safety margins of modern intensity-modulated radiotherapy (IMRT) in patients with high-grade meningiomas on local control and recurrenc...

    Authors: Barbara Zollner, Ute Ganswindt, Cornelius Maihöfer, Stefanie Corradini, Nathalie Lisa Albert, Christian Schichor, Claus Belka and Maximilian Niyazi

    Citation: Radiation Oncology 2018 13:110

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  16. Content type: Research

    Ion beam radiotherapy provides potential for increased dose conformation to the target volume. To translate it into a clinical advantage, it is necessary to guarantee a precise alignment of the actual internal...

    Authors: M. Martišíková, T. Gehrke, S. Berke, G. Aricò and O. Jäkel

    Citation: Radiation Oncology 2018 13:109

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  17. Content type: Research

    The purpose of this study was to evaluate the impact of markerless on-board kilovoltage (kV) cone-beam computed tomography (CBCT)-based positioning uncertainty on determination of the planning target volume (P...

    Authors: Katsumi Hirose, Mariko Sato, Yoshiomi Hatayama, Hideo Kawaguchi, Fumio Komai, Makoto Sohma, Hideki Obara, Masashi Suzuki, Mitsuki Tanaka, Ichitaro Fujioka, Koji Ichise, Yoshihiro Takai and Masahiko Aoki

    Citation: Radiation Oncology 2018 13:106

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  18. Content type: Research

    The use of intraprostatic gold fiducial markers (FMs) ensures highly accurate and precise image-guided radiation therapy for patients diagnosed with prostate cancer thanks to the ease of localising FMs on phot...

    Authors: Matteo Maspero, Peter R. Seevinck, Nicole J. W. Willems, Gonda G. Sikkes, Geja J. de Kogel, Hans C. J. de Boer, Jochem R. N. van der Voort van Zyp and Cornelis A. T. van den Berg

    Citation: Radiation Oncology 2018 13:105

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  19. Content type: Research

    Brain metastasis is becoming increasingly prevalent in breast cancer due to improved extra-cranial disease control. With emerging availability of modern image-guided radiation platforms, mouse models of brain ...

    Authors: Niloufar Zarghami, Donna H. Murrell, Michael D. Jensen, Frederick A. Dick, Ann F. Chambers, Paula J. Foster and Eugene Wong

    Citation: Radiation Oncology 2018 13:104

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  20. Content type: Research

    While breast radiotherapy typically includes regional nodal basins, the treatment of the internal mammary nodes (IMN) has been controversial due to concern for long-term cardiac toxicity. For high risk patient...

    Authors: Macklin H. Nguyen, Myra Lavilla, Janice N. Kim and L. Christine Fang

    Citation: Radiation Oncology 2018 13:103

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  21. Content type: Case report

    The existence of abscopal effects has been suggested already a long time ago, but only recently with the advent of immune checkpoint inhibition in clinical oncology and modern imaging techniques has it become ...

    Authors: Christian Britschgi, Oliver Riesterer, Irene A. Burger, Matthias Guckenberger and Alessandra Curioni-Fontecedro

    Citation: Radiation Oncology 2018 13:102

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  22. Content type: Research

    While intensity modulated radiotherapy (IMRT) has been widely adopted for the treatment of anal cancer (AC), the added contour complexity poses potential risks. This study investigates the impact of contour va...

    Authors: Michael P. Jones, Jarad Martin, Kerwyn Foo, Patrick Estoesta, Lois Holloway and Michael Jameson

    Citation: Radiation Oncology 2018 13:97

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  23. Content type: Review

    Prediction of radiobiological response is a major challenge in radiotherapy. Of several radiobiological models, the linear-quadratic (LQ) model has been best validated by experimental and clinical data. Clinic...

    Authors: C. M. van Leeuwen, A. L. Oei, J. Crezee, A. Bel, N. A. P. Franken, L. J. A. Stalpers and H. P. Kok

    Citation: Radiation Oncology 2018 13:96

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  24. Content type: Research

    A new strategy for making the appropriate choice of the representative optimization parameters in planning processes and accurate selection criteria during Pareto surface navigation for general multicriteria o...

    Authors: Juanqi Wang, Zhi Chen, Weiwei Li, Wei Qian, Xiaosheng Wang and Weigang Hu

    Citation: Radiation Oncology 2018 13:94

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  25. Content type: Research

    To analyse the outcome of elderly patients (≥70 years) with esophageal cancer treated with curative intent radio(chemo)therapy.

    Authors: Franziska Walter, David Böckle, Nina-Sophie Schmidt-Hegemann, Rebecca Köpple, Sabine Gerum, Stefan Boeck, Martin Angele, Claus Belka and Falk Roeder

    Citation: Radiation Oncology 2018 13:93

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  26. Content type: Research

    IMRT provides higher dose conformation to the target and dose sparing to surrounding tissues than 3DCRT. Monte Carlo method in Medical Physics is not a novelty to approach dosimetric problems. A new PENELOPE b...

    Authors: Alessandro Esposito, Sofia Silva, Jorge Oliveira, Joana Lencart and João Santos

    Citation: Radiation Oncology 2018 13:91

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  27. Content type: Review

    68Gallium prostate specific membrane antigen (PSMA) ligand positron emission tomography (PET) is an increasingly used imaging modality in prostate cancer, especially in cases of tumor recurrence after curative i....

    Authors: Sebastian Zschaeck, Fabian Lohaus, Marcus Beck, Gregor Habl, Stephanie Kroeze, Constantinos Zamboglou, Stefan Alexander Koerber, Jürgen Debus, Tobias Hölscher, Peter Wust, Ute Ganswindt, Alexander D. J. Baur, Klaus Zöphel, Nikola Cihoric, Matthias Guckenberger, Stephanie E. Combs…

    Citation: Radiation Oncology 2018 13:90

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  28. Content type: Research

    Resistance to radiotherapy is frequently encountered in patients with glioblastoma multiforme. It is caused at least partially by the high glutathione content in the tumour tissue. Therefore, the administratio...

    Authors: E. Schültke, E. Bräuer-Krisch, H. Blattmann, H. Requardt, J. A. Laissue and G. Hildebrandt

    Citation: Radiation Oncology 2018 13:89

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  29. Content type: Research

    The loco regional relapse is frequent in the lung disease. The aim of this study was to evaluate the outcomes of re-irradiation by SBRT in terms of Local Control (LC) and toxicities.

    Authors: Donatella Caivano, Maurizio Valeriani, Sara De Matteis, Paolo Bonome, Ivana Russo, Vitaliana De Sanctis, Giuseppe Minniti and Mattia Falchetto Osti

    Citation: Radiation Oncology 2018 13:87

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  30. Content type: Research

    With the advance of modern irradiation techniques, the role of radiotherapy (RT) for intracranial meningioma has increased significantly throughout the past years. Despite that tumor’s generally favorable outc...

    Authors: Rami A. El Shafie, Maja Czech, Kerstin A. Kessel, Daniel Habermehl, Dorothea Weber, Stefan Rieken, Nina Bougatf, Oliver Jäkel, Jürgen Debus and Stephanie E. Combs

    Citation: Radiation Oncology 2018 13:86

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  31. Content type: Research

    The role of adjuvant radiotherapy (RT) and setting proper RT target volumes have not been clearly demonstrated for extrahepatic bile duct (EHBD) cancer, due to the rarity of the disease and the lack of randomi...

    Authors: Hoon Sik Choi, Ki Mun Kang, Bae Kwon Jeong, Hojin Jeong, Yun Hee Lee, In Bong Ha, Tae Gyu Kim and Jin Ho Song

    Citation: Radiation Oncology 2018 13:85

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  32. Content type: Research

    L’Hermitte’s sign (LS) after chemoradiotherapy for head and neck cancer appears related to higher spinal cord doses. IMRT plans limit spinal cord dose, but the incidence of LS remains high.

    Authors: Hannah M. Laidley, David J. Noble, Gill C. Barnett, Julia R. Forman, Amy M. Bates, Richard J. Benson, Sarah J. Jefferies, Rajesh Jena and Neil G. Burnet

    Citation: Radiation Oncology 2018 13:84

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  33. Content type: Research

    Concurrent chemo-radiation (CT-RT) is a standard therapy for squamous cell carcinoma of anal canal. Different clinical and biological factors may potentially affect outcome. We investigated the prognostic role...

    Authors: Pierfrancesco Franco, Francesco Montagnani, Francesca Arcadipane, Chiara Casadei, Kalliopi Andrikou, Stefania Martini, Giuseppe Carlo Iorio, Mario Scartozzi, Massimiliano Mistrangelo, Lorenzo Fornaro, Paola Cassoni, Stefano Cascinu, Umberto Ricardi and Andrea Casadei Gardini

    Citation: Radiation Oncology 2018 13:83

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  34. Content type: Research

    Previous studies reported that patients with preexisting radiological interstitial lung abnormalities (ILAs) were more susceptible to developing radiation pneumonitis (RP) after thoracic radiation therapy (TRT...

    Authors: Fangjuan Li, Ziyang Zhou, Ailu Wu, Yong Cai, Hongyu Wu, Ming Chen and Shixiong Liang

    Citation: Radiation Oncology 2018 13:82

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  35. Content type: Research

    Focal radiation therapy has gained of interest in treatment of patients with primary prostate cancer (PCa). The question of how to define the intraprostatic boost volume is still open. Previous studies showed ...

    Authors: Constantinos Zamboglou, Benedikt Thomann, Khodor Koubar, Peter Bronsert, Tobias Krauss, Hans C. Rischke, Ilias Sachpazidis, Vanessa Drendel, Nasr Salman, Kathrin Reichel, Cordula A. Jilg, Martin Werner, Philipp T. Meyer, Michael Bock, Dimos Baltas and Anca L. Grosu

    Citation: Radiation Oncology 2018 13:81

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  36. Content type: Research

    To evaluate the effect of pretreatment megavoltage computed tomographic (MVCT) scan methodology on setup verification and adaptive dose calculation in helical TomoTherapy.

    Authors: Jian Zhu, Tong Bai, Jiabing Gu, Ziwen Sun, Yumei Wei, Baosheng Li and Yong Yin

    Citation: Radiation Oncology 2018 13:80

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  37. Content type: Retraction Note

    The authors are retracting this article [1] because the data have already been published in [2] making this a redundant publication. Ghazi Alsbeih, Najla Al-Harbi, Khaled Al-Hadyan, Mohamed Shoukri and Nasser ...

    Authors: Ghazi Alsbeih, Medhat El-Sebaie, Najla Al-Harbi, Khaled Al-Hadyan, Mohamed Shoukri and Nasser Al-Rajhi

    Citation: Radiation Oncology 2018 13:79

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    The original article was published in Radiation Oncology 2013 8:125

  38. Content type: Research

    The principle aim of this study is to incorporate 4DCT ventilation imaging into functional treatment planning that preserves high-functioning lung with both double scattering and scanning beam techniques in pr...

    Authors: Qijie Huang, Salma K. Jabbour, Zhiyan Xiao, Ning Yue, Xiao Wang, Hongbin Cao, Yu Kuang, Yin Zhang and Ke Nie

    Citation: Radiation Oncology 2018 13:78

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  39. Content type: Research

    SBRT is standard therapy for early stage lung cancer. Toxicity in central tumors has been a concern. RTOG 0813 showed that central SBRT is safe and effective. We report our experience with central SBRT.

    Authors: Yasmin Korzets ceder, Eyal Fenig, Aron Popvtzer, Nir Peled, Mordechai R. Kramer, Milton Saute, Dima Bragilovsky, Tzippy Schochat and Aaron M. Allen

    Citation: Radiation Oncology 2018 13:77

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  40. Content type: Short Report

    Ataxia Telangiectasia and Rad3 related protein (ATR) is a central mediator of the response to DNA damage that may cause the quiescent resistance of cancer initiating cells to genotoxic radiotherapy. NVP-BEZ235...

    Authors: Guido Fròsina, Aldo Profumo, Daniela Marubbi, Diana Marcello, Jean Louis Ravetti and Antonio Daga

    Citation: Radiation Oncology 2018 13:76

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  41. Content type: Research

    Oligo-recurrence has been considered to confer improved prognosis than other oligometastatic conditions, and stereotactic body radiation therapy (SBRT) is considered as an option of local therapy for lung or l...

    Authors: Masaki Nakamura, Naoki Hashimoto, Hiroshi Mayahara, Haruka Uezono, Aya Harada, Ryo Nishikawa, Yoshiro Matsuo, Hiroki Kawaguchi and Hideki Nishimura

    Citation: Radiation Oncology 2018 13:75

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  42. Content type: Research

    Postoperative/adjuvant radiotherapy of advanced gastric cancer involves a large planning target volume (PTV) with multi-concave shapes which presents a challenge for volumetric modulated arc therapy (VMAT) pla...

    Authors: Abdul Wahab M. Sharfo, Florian Stieler, Oskar Kupfer, Ben J. M. Heijmen, Maarten L. P. Dirkx, Sebastiaan Breedveld, Frederik Wenz, Frank Lohr, Judit Boda-Heggemann and Daniel Buergy

    Citation: Radiation Oncology 2018 13:74

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