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  1. Some patients have noted a foul odor during radiation therapy sessions, but the cause of the odor remains unknown. Since we suspected that this phenomenon is due to ozone generated by ionizing radiation, this ...

    Authors: N. Hara, J. Oobuchi, A. Isobe, S. Sugimoto, J. Takatsu and K. Sasai
    Citation: Radiation Oncology 2022 17:39
  2. Boosting dominant intra-prostatic lesions (DILs) has the potential to increase the therapeutic ratio in prostate cancer radiotherapy. In this study, employing 5-fraction stereotactic ablative radiotherapy (SAB...

    Authors: Sarah O. S. Osman, Ciaran Fairmichael, Glenn Whitten, Gavin S. Lundy, Rachel Wesselman, Melissa LaBonte Wilson, Alan R. Hounsell, Kevin M. Prise, Denise Irvine, Conor K. McGarry and Suneil Jain
    Citation: Radiation Oncology 2022 17:38
  3. The use of stereotactic body radiation therapy (SBRT) for tumor and pain control in patients with bone metastases is increasing. We report response assessment after bone SBRT using radiological changes through...

    Authors: Dora Correia, Barbara Moullet, Jennifer Cullmann, Rafael Heiss, Ekin Ermiş, Daniel M. Aebersold and Hossein Hemmatazad
    Citation: Radiation Oncology 2022 17:37
  4. The impact of radiotherapy interruption due to the Spring Festival holidays in China on the survival of patients with nasopharyngeal carcinoma (NPC) is unclear.

    Authors: Cheng Xu, Kai-Bin Yang, Rui-Jia Feng, Lei Chen, Xiao-Jing Du, Yan-Ping Mao, Wen-Fei Li, Qing Liu, Ying Sun and Jun Ma
    Citation: Radiation Oncology 2022 17:36
  5. This study aimed to investigate preoperative spirometry and BMI as early predictors of the mean heart and lung dose (MHD, MLD) in deep inspiration breath-hold (DIBH) radiotherapy.

    Authors: Yutaro Koide, Hidetoshi Shimizu, Takahiro Aoyama, Tomoki Kitagawa, Risei Miyauchi, Yui Watanabe, Hiroyuki Tachibana and Takeshi Kodaira
    Citation: Radiation Oncology 2022 17:35
  6. Vaginal bleeding (VB) is common in women with gynecologic (GYN) malignancies. Radiation therapy (RT) is used for the definitive treatment of GYN cancers and palliation of bleeding. The historical dogma is that...

    Authors: Luke A. Moradi, Craig S. Schneider, Alok S. Deshane, Richard A. Popple, Robert Y. Kim and Samuel R. Marcrom
    Citation: Radiation Oncology 2022 17:34
  7. To date, no data on the effect of adjuvant postmastectomy radiotherapy (PMRT) on oncologic outcomes, such as all-cause death, locoregional recurrence (LRR), and distant metastasis (DM), are available in women ...

    Authors: Jiaqiang Zhang, Shao-Yin Sum, Jeng-Guan Hsu, Ming-Feng Chiang, Tian-Shyug Lee and Szu-Yuan Wu
    Citation: Radiation Oncology 2022 17:33
  8. Factors associated with long-term survival in gemcitabine-concurrent proton radiotherapy (GPT) for non-metastatic, locally advanced pancreatic cancer (LAPC) remain unclear. This study aimed to determine the fa...

    Authors: Yuta Ogura, Kazuki Terashima, Yoshihide Nanno, SungChul Park, Masaki Suga, Daiki Takahashi, Yoshiro Matsuo, Nor Shazrina Sulaiman, Sunao Tokumaru, Tomoaki Okimoto, Hirochika Toyama and Takumi Fukumoto
    Citation: Radiation Oncology 2022 17:32
  9. This paper describes the development of a predicted electronic portal imaging device (EPID) transmission image (TI) using Monte Carlo (MC) and deep learning (DL). The measured and predicted TI were compared fo...

    Authors: Jun Zhang, Zhibiao Cheng, Ziting Fan, Qilin Zhang, Xile Zhang, Ruijie Yang and Junhai Wen
    Citation: Radiation Oncology 2022 17:31
  10. Several studies have reported patient-related risk factors for late rectal bleeding following conventionally fractionated radiotherapy for prostate cancer. We investigated patient-related risk factors for late...

    Authors: Tae Gyu Kim, Byungdo Park, Yun Gyu Song, Hyoun Wook Lee, Tae Hee Oh, Dong-Soo Ryu, Seung Chan Jeong, Daehyeon Cho, Jieun Oh, Kwang Min Kim, Jung Won Lee, Hyoun Soo Lee, Sung Min Kong, Jun Young Kim and Haeyoung Kim
    Citation: Radiation Oncology 2022 17:30
  11. Stage III non-small cell lung cancer (NSCLC) represents a highly heterogeneous disease and treatment burden. Advances in imaging modality show promising results for radiotherapy planning. In this multicentric ...

    Authors: Matthias Mäurer, Lukas Käsmann, Daniel F. Fleischmann, Michael Oertel, Danny Jazmati and Daniel Medenwald
    Citation: Radiation Oncology 2022 17:29
  12. With the rapid growth of deep learning research for medical applications comes the need for clinical personnel to be comfortable and familiar with these techniques. Taking a proven approach, we developed a str...

    Authors: John C. Asbach, Anurag K. Singh, L. Shawn Matott and Anh H. Le
    Citation: Radiation Oncology 2022 17:28
  13. Current literature lacks a comparison of lymph node metastases and non-pathological lymph nodes distribution in breast cancer patients. The aim of the current retrospective study was to generate a comprehensiv...

    Authors: Kai J. Borm, Lucia Ernst, Julia Voppichler, Markus Oechsner, Mathias Düsberg, Gabriel Buschner, Wolfgang Weber, Stephanie E. Combs and Marciana N. Duma
    Citation: Radiation Oncology 2022 17:27
  14. In the modern era of magnetic resonance imaging (MRI) staging, the benefit of prophylactic cranial irradiation (PCI) in patients with small-cell lung cancer (SCLC) has been controversial. This study evaluated ...

    Authors: Yu Jin Lim, Changhoon Song and Hak Jae Kim
    Citation: Radiation Oncology 2022 17:26
  15. Artificial intelligence (AI) shows great potential to streamline the treatment planning process. However, its clinical adoption is slow due to the limited number of clinical evaluation studies and because ofte...

    Authors: Esther Kneepkens, Nienke Bakx, Maurice van der Sangen, Jacqueline Theuws, Peter-Paul van der Toorn, Dorien Rijkaart, Jorien van der Leer, Thérèse van Nunen, Els Hagelaar, Hanneke Bluemink and Coen Hurkmans
    Citation: Radiation Oncology 2022 17:25
  16. To develop an auxiliary GPU-accelerated proton therapy (PT) dose and LETd engine for the IBA Proteus®ONE PT system. A pediatric low-grade glioma case study is reported using FRoG during clinical practice, highlig...

    Authors: Stewart Mein, Benedikt Kopp, Anthony Vela, Pauline Dutheil, Paul Lesueur, Dinu Stefan, Jürgen Debus, Thomas Haberer, Amir Abdollahi, Andrea Mairani and Thomas Tessonnier
    Citation: Radiation Oncology 2022 17:23
  17. Respiratory motion may introduce errors during radiotherapy. This study aims to assess and validate internal gross tumour volume (IGTV) margins in proximal and distal borders of gastroesophageal junction (GEJ)...

    Authors: Jinming Shi, Yuan Tang, Ning Li, Yongwen Song, Shulian Wang, Yueping Liu, Hui Fang, Ningning Lu, Yu Tang, Shunan Qi, Bo Chen, Yexiong Li, Wenyang Liu and Jing Jin
    Citation: Radiation Oncology 2022 17:22
  18. The evaluation of automatic segmentation algorithms is commonly performed using geometric metrics. An analysis based on dosimetric parameters might be more relevant in clinical practice but is often lacking in...

    Authors: Maria Kawula, Dinu Purice, Minglun Li, Gerome Vivar, Seyed-Ahmad Ahmadi, Katia Parodi, Claus Belka, Guillaume Landry and Christopher Kurz
    Citation: Radiation Oncology 2022 17:21
  19. Ultrahypofractionation can shorten the irradiation period. This study is the first dosimetric investigation comparing ultrahypofractionation using volumetric arc radiation therapy (VMAT) and intensity-modulate...

    Authors: Puntiwa Oonsiri, Chonnipa Nantavithya, Chawalit Lertbutsayanukul, Thanaporn Sarsitthithum, Mananchaya Vimolnoch, Tanawat Tawonwong and Kitwadee Saksornchai
    Citation: Radiation Oncology 2022 17:20
  20. Prostate cancer is the most common cancer among men, and its diagnosis and treatment are improving. Our study evaluated how PSMA-PET/CT prior to treatment planning might improve the optimal management of prost...

    Authors: Vasileios Karagiannis, Viktor Wichmann, Juha Saarinen, Natalja Eigeliene, Heidi Andersen and Antti Jekunen
    Citation: Radiation Oncology 2022 17:19
  21. Pain symptoms in the upper abdomen and back are prevalent in 80% of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC), where the current standard treatment is a systemic therapy consisting of a...

    Authors: M. Pavic, M. Niyazi, L. Wilke, S. Corradini, M. Vornhülz, U. Mansmann, A. Al Tawil, R. Fritsch, J. Hörner-Rieber, J. Debus, M. Guckenberger, C. Belka, J. Mayerle and G. Beyer
    Citation: Radiation Oncology 2022 17:18
  22. Radiotherapy (RT) is a mainstay of treatment for patients with glioblastoma (GB). Early clinical trials show that short course hypofractionation showed no survival benefit compared to conventional regimens wit...

    Authors: Kelly J. McKelvey, Amanda L. Hudson, Heather Donaghy, Shihani P. Stoner, Helen R. Wheeler, Connie I. Diakos and Viive M. Howell
    Citation: Radiation Oncology 2022 17:17
  23. The 106-Ruthenium contact plaque applicator is utilized for the treatment of intraocular tumor within a thickness of less than 6 mm. If anything obstructs the placement of the plaque applicator, the treatment ...

    Authors: Satoshi Nakamura, Naoya Murakami, Shigenobu Suzuki, Kimiteru Ito, Mihiro Takemori, Hiroki Nakayama, Keita Kaga, Takahito Chiba, Kotaro Iijima, Kana Takahashi, Tomonori Goka, Jun Itami, Hiroyuki Okamoto and Hiroshi Igaki
    Citation: Radiation Oncology 2022 17:16
  24. Although glioblastoma (GB) is associated with a devastating prognosis, a small proportion of patients achieve long-term survival rates. We herein present a matched-pair analysis of molecular factors found in l...

    Authors: Vivien N. Sommerlath, Daniel Buergy, Nima Etminan, Stefanie Brehmer, David Reuss, Gustavo R. Sarria, Marie-Christin Guiot, Daniel Hänggi, Frederik Wenz, Kevin Petrecca and Frank A. Giordano
    Citation: Radiation Oncology 2022 17:15
  25. The addition of consolidation chemotherapy to preoperative short-course radiotherapy during the prolonged interval between the completion of radiation and surgery in locally advanced rectal cancer (LARC) could...

    Authors: Haoyan Wu, Chuanwen Fan, Chao Fang, Libin Huang, Yuan Li and Zongguang Zhou
    Citation: Radiation Oncology 2022 17:14
  26. To define the clinical characteristics of irradiation-induced nasopharyngeal necrosis (INN) after intensity-modulated radiotherapy (IMRT) and identify the influence of treatment strategies on INN in primary na...

    Authors: Yi Xu, Yang Liu, Zekun Wang, Jingbo Wang, Jianghu Zhang, Xuesong Chen, Runye Wu, Qingfeng Liu, Yuan Qu, Kai Wang, Xiaodong Huang, Jingwei Luo, Li Gao, Guozhen Xu, Ye Zhang and Junlin Yi
    Citation: Radiation Oncology 2022 17:13
  27. To evaluate acute and late genitourinary and gastrointestinal toxicities and patient reported urinary and sexual function following accelerated, hypofractionated external beam radiotherapy to the prostate, sem...

    Authors: Christina Phuong, Jason W. Chan, Lisa Ni, Phillip Wall, Osama Mohamad, Anthony C. Wong, I.-Chow Hsu and Albert J. Chang
    Citation: Radiation Oncology 2022 17:12
  28. Although chemoradiotherapy (CRT) is one of the curative treatments for thoracic esophageal squamous cell carcinoma (ESCC) with submucosal invasion, the risk of local recurrence after CRT remains a clinical pro...

    Authors: Tomohiko Miyazaki, Miyako Myojin, Masao Hosokawa, Hidefumi Aoyama, Satoshi Okahara and Hiroaki Takahashi
    Citation: Radiation Oncology 2022 17:11
  29. Low dose radiotherapy (LDRT) of whole lungs with photon beams is a novel method for treating COVID-19 pneumonia. This study aimed to estimate cancer risks induced by lung LDRT for different radiotherapy delive...

    Authors: Amin Banaei, Bijan Hashemi and Mohsen Bakhshandeh
    Citation: Radiation Oncology 2022 17:10
  30. Chemoradiotherapy (CRT) followed by a brachytherapy (BT) boost is the standard of care for patients with locally advanced or recurrent gynecological cancer (LARGC). However, not every patient is suitable for B...

    Authors: Indrawati Hadi, Chukwuka Eze, Stephan Schönecker, Rieke von Bestenbostel, Paul Rogowski, Lukas Nierer, Raphael Bodensohn, Michael Reiner, Guillaume Landry, Claus Belka, Maximilian Niyazi and Stefanie Corradini
    Citation: Radiation Oncology 2022 17:8
  31. Concurrent chemoradiotherapy (CCRT) followed by durvalumab is the standard of care for unresectable locally-advanced non-small cell carcinoma (LA-NSCLC). However, a major concern about administration of durval...

    Authors: Hiroshi Mayahara, Kazuyuki Uehara, Aya Harada, Keiji Kitatani, Tomonori Yabuuchi, Shuichirou Miyazaki, Takeaki Ishihara, Hiroki Kawaguchi, Hikaru Kubota, Hideaki Okada, Taira Ninomaru, Chihiro Shindo and Akito Hata
    Citation: Radiation Oncology 2022 17:7
  32. To investigate the prognostic relevance of specific measurement parameters such as tumor diameter, tumor volume, tumor volume reduction rate (TVRR), and changes in the squamous cell carcinoma antigen (SCC-Ag) ...

    Authors: Wenjuan Chen, Siyi Xiu, Xingyun Xie, Huiming Guo, Yuanji Xu, Penggang Bai and Xiaoyi Xia
    Citation: Radiation Oncology 2022 17:6
  33. To characterise the motion of pulmonary tumours during stereotactic body radiation therapy (SBRT) and to evaluate different margins when creating the planning target volume (PTV) on a single 4D CT scan (4DCT).

    Authors: Pierre Trémolières, Ana Gonzalez-Moya, Amaury Paumier, Martine Mege, Julien Blanchecotte, Christelle Theotime, Damien Autret and Stéphane Dufreneix
    Citation: Radiation Oncology 2022 17:5
  34. Re-irradiation (re-RT) is a technically challenging task for which few standardized approaches exist. This is in part due to the lack of a common platform to assess dose tolerance in relation to toxicity in th...

    Authors: Eric D. Brooks, Xiaochun Wang, Brian De, Vivek Verma, Tyler D. Williamson, Rachel Hunter, Abdallah S. R. Mohamed, Matthew S. Ning, Xiaodong Zhang and Joe Y. Chang
    Citation: Radiation Oncology 2022 17:4
  35. High-quality radiotherapy (RT) planning for children and young adults with primary brain tumours is essential to minimize the risk of late treatment effects. The feasibility of using automated machine-learning...

    Authors: Derek S. Tsang, Grace Tsui, Chris McIntosh, Thomas Purdie, Glenn Bauman, Hitesh Dama, Normand Laperriere, Barbara-Ann Millar, David B. Shultz, Sameera Ahmed, Mohammad Khandwala and David C. Hodgson
    Citation: Radiation Oncology 2022 17:3
  36. Adjuvant radiotherapy following surgery reduces the local recurrence and improves the prognosis. However, a considerable part of patients developed digestive reaction in daily treatment. In order to explore th...

    Authors: Dong Yang, Ying Piao, Fengshun Yuan, Hongtao Chen, Ding Zhang and Xianming Li
    Citation: Radiation Oncology 2022 17:2
  37. To evaluate the sensitivity to set up the uncertainty of VMAT plans in Nasopharyngeal carcinoma (NPC) treatment by proposing a plan robustness evaluation method.

    Authors: Zhen Ding, Xiaoyong Xiang, Qi Zeng, Jun Ma, Zhitao Dai, Kailian Kang and Suyan Bi
    Citation: Radiation Oncology 2022 17:1
  38. Boron neutron capture therapy (BNCT) for the treatment of unresectable, locally advanced, and recurrent carcinoma of the head and neck cancer has been approved by the Japanese government for reimbursement unde...

    Authors: Naonori Hu, Hiroki Tanaka, Ryo Kakino, Syuushi Yoshikawa, Mamoru Miyao, Kazuhiko Akita, Kayako Isohashi, Teruhito Aihara, Keiji Nihei and Koji Ono
    Citation: Radiation Oncology 2021 16:243
  39. The purpose of this study was to determine if vertebral body and splenic dosimetry was associated with the development of lymphopenia in patients with borderline resectable (BRPC) and locally advanced pancreat...

    Authors: Abhinav V. Reddy, Matthew P. Deek, Juan F. Jackson, Colin S. Hill, Shuchi Sehgal, Jin He, Lei Zheng, Joseph M. Herman, Jeffrey Meyer and Amol K. Narang
    Citation: Radiation Oncology 2021 16:242
  40. Cardiac effects after breast cancer radiation therapy potentially affect more patients as survival improves. The heart’s heterogeneous radiation exposure and composition of functional structures call for estab...

    Authors: Marcus Stockinger, Heiko Karle, Hannes Rennau, Sabine Sebb, Ulrich Wolf, Julia Remmele, Sandra Bührdel, Detlef Bartkowiak, Maria Blettner, Heinz Schmidberger and Daniel Wollschläger
    Citation: Radiation Oncology 2021 16:241
  41. Radiation therapy is an integral part of the multimodal primary therapy of glioblastomas. As the overall prognosis in this tumor entity remains unfavorable, current research is focused on additional drug thera...

    Authors: Laila König, Cornelia Jäkel, Nikolaus von Knebel Doeberitz, Meinhard Kieser, Fabian Eberle, Marc Münter, Jürgen Debus and Klaus Herfarth
    Citation: Radiation Oncology 2021 16:240
  42. Radio-chemotherapy with CDDP is the standard for H&N squamous cell cancer. CDDP 100 mg/m2/q3 is the standard; alternative schedules are used to reduce toxicity, mostly 40 mg/m2/q1.

    Authors: Michela Buglione, Daniela Alterio, Marta Maddalo, Diana Greco, Marianna Alessandra Gerardi, Davide Tomasini, Ludovica Pegurri, Matteo Augugliaro, Giulia Marvaso, Irene Turturici, Andrea Guerini, Mohssen Ansarin, Luigi Spiazzi, Loredana Costa, Maria Cossu Rocca, Stefano Maria Magrini…
    Citation: Radiation Oncology 2021 16:239
  43. This study presents an analysis (efficacy and toxicity) of outcomes in patients with skull-base chordomas or chondrosarcomas treated with a fixed horizontal pencil proton beam.

    Authors: Konstantin Gordon, Igor Gulidov, Sergey Koryakin, Daniil Smyk, Tatyana Makeenkova, Danil Gogolin, Olga Lepilina, Olga Golovanova, Alexey Semenov, Sergey Dujenko, Kira Medvedeva and Yuri Mardynsky
    Citation: Radiation Oncology 2021 16:238
  44. Magnetic Resonance Image guided Stereotactic body radiotherapy (MRgRT) is an emerging technology that is increasingly used in treatment of visceral cancers, such as pancreatic adenocarcinoma (PDAC). Given the ...

    Authors: M. R. Tomaszewski, K. Latifi, E. Boyer, R. F. Palm, I. El Naqa, E. G. Moros, S. E. Hoffe, S. A. Rosenberg, J. M. Frakes and R. J. Gillies
    Citation: Radiation Oncology 2021 16:237
  45. The use of total body irradiation (TBI) with linac-based volumetric modulated arc therapy (VMAT) has been steadily increasing. Helical tomotherapy has been applied in TBI and total marrow irradiation to reduce...

    Authors: Takuya Uehara, Hajime Monzen, Mikoto Tamura, Masahiro Inada, Masakazu Otsuka, Hiroshi Doi, Kenji Matsumoto and Yasumasa Nishimura
    Citation: Radiation Oncology 2021 16:236

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