Radiation Physics

Section edited by Christoph Bert and Katia Parodi

The Radiation Physics section aims at providing a platform for medical physics research and applications in radiation oncology. This includes innovative developments in the application of physical sciences to radiation oncology, spanning the broad range of advanced beam delivery and imaging, dosimetry, computation, modeling and data processing. Contributions proposing innovative methodological approaches or presenting original assessment on the clinical relevance of new technologies are welcome. Space is also given to review contributions on timely topics, as well as invited key reviews from renowned experts. Hence, the Radiation Physics section addresses contemporary cutting-edge research and methodological advancements for improved clinical practice, as well as reviews of relevant medical physics issues in radiation oncology, offering a fast review process and broad outreach.

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  1. Research

    Comprehensive target geometric errors and margin assessment in stereotactic partial breast irradiation

    Recently developed stereotactic partial breast irradiation (S-PBI) allows delivery of a high biologically potent dose to the target while sparing adjacent critical organs and normal tissue. With S-PBI tumorici...

    Xin Zhen, Bo Zhao, Zhuoyu Wang, Robert Timmerman, Ann Spangler, Nathan Kim, Asal Rahimi and Xuejun Gu

    Radiation Oncology 2017 12:151

    Published on: 11 September 2017

  2. Research

    Cone-beam CT reconstruction for non-periodic organ motion using time-ordered chain graph model

    The purpose of this study is to introduce the new concept of a four-dimensional (4D) cone-beam computed tomography (CBCT) reconstruction approach for non-periodic organ motion in cooperation with the time-orde...

    Masahiro Nakano, Akihiro Haga, Jun’ichi Kotoku, Taiki Magome, Yoshitaka Masutani, Shouhei Hanaoka, Satoshi Kida and Keiichi Nakagawa

    Radiation Oncology 2017 12:145

    Published on: 4 September 2017

  3. Research

    Comparison of photon volumetric modulated arc therapy, intensity-modulated proton therapy, and intensity-modulated carbon ion therapy for delivery of hypo-fractionated thoracic radiotherapy

    The aim of the present study was to compare the dose distribution generated from photon volumetric modulated arc therapy (VMAT), intensity modulated proton therapy (IMPT), and intensity modulated carbon ion th...

    Alexander Chi, Lien-Chun Lin, Sijin Wen, Haijuan Yan and Wen-Chien Hsi

    Radiation Oncology 2017 12:132

    Published on: 15 August 2017

  4. Research

    Understanding the potentiality of accelerator based-boron neutron capture therapy for osteosarcoma: dosimetry assessment based on the reported clinical experience

    Osteosarcoma is the most frequent primary malignant bone tumour, and its incidence is higher in children and adolescents, for whom it represents more than 10% of solid cancers. Despite the introduction of adju...

    Silva Bortolussi, Ian Postuma, Nicoletta Protti, Lucas Provenzano, Cinzia Ferrari, Laura Cansolino, Paolo Dionigi, Olimpio Galasso, Giorgio Gasparini, Saverio Altieri, Shin-Ichi Miyatake and Sara J. González

    Radiation Oncology 2017 12:130

    Published on: 15 August 2017

  5. Research

    A novel CBCT-based method for derivation of CTV-PTV margins for prostate and pelvic lymph nodes treated with stereotactic ablative radiotherapy

    Traditional CTV-PTV margin recipes are not generally applicable in the situation of stereotactic ablative radiotherapy (SABR) treatments of multiple target volumes with a single isocentre. In this work, we pre...

    Ciara A. Lyons, Raymond B. King, Sarah O.S. Osman, Stephen J. McMahon, Joe M. O’Sullivan, Alan R. Hounsell, Suneil Jain and Conor K. McGarry

    Radiation Oncology 2017 12:124

    Published on: 4 August 2017

  6. Research

    Clinical workflow for MR-only simulation and planning in prostate

    To describe the details and experience of implementing a MR-only workflow in the clinic for simulation and planning of prostate cancer patients.

    Neelam Tyagi, Sandra Fontenla, Michael Zelefsky, Marcia Chong-Ton, Kyle Ostergren, Niral Shah, Lizette Warner, Mo Kadbi, Jim Mechalakos and Margie Hunt

    Radiation Oncology 2017 12:119

    Published on: 17 July 2017

  7. Research

    Investigation of irradiated volume in linac-based brain hypo-fractionated stereotactic radiotherapy

    Emerging techniques such as brain hypo-fractionated radiotherapy (HF-RT) involve complex cases with limited guidelines for plan quality and normal tissue tolerances. The purpose of the present study was to sta...

    Mark Ruschin, Arjun Sahgal, Hany Soliman, Sten Myrehaug, May Tsao, Collins Yeboah, Arman Sarfehnia, Brige Chugh, Alex Kiss and Young Lee

    Radiation Oncology 2017 12:117

    Published on: 14 July 2017

  8. Research

    Simultaneous integrated boost therapy of carcinoma of the hypopharynx/larynx with and without flattening filter - a treatment planning and dosimetry study

    The aim of this study was to investigate if the flattening filter free (FFF) irradiation mode of a linear accelerator (linac) is advantageous as compared to the flat beam (FF) irradiation mode in intensity mod...

    Barbara Dobler, Tina Obermeier, Matthias G. Hautmann, Amine Khemissi and Oliver Koelbl

    Radiation Oncology 2017 12:114

    Published on: 5 July 2017

  9. Research

    Analyzing human decisions in IGRT of head-and-neck cancer patients to teach image registration algorithms what experts know

    In IGRT of deformable head-and-neck anatomy, patient setup corrections are derived by rigid registration methods. In practice, experienced radiation therapists often correct the resulting vectors, thus indicat...

    Eva Maria Stoiber, Nina Bougatf, Hendrik Teske, Christian Bierstedt, Dieter Oetzel, Jürgen Debus, Rolf Bendl and Kristina Giske

    Radiation Oncology 2017 12:104

    Published on: 21 June 2017

  10. Research

    Treating lung cancer with dynamic conformal arc therapy: a dosimetric study

    Lung cancer patients are often in poor physical condition, and a shorter treatment time would reduce their discomfort. Dynamic conformal arc therapy (DCAT) offers a shorter treatment time than conventional 3D ...

    Primož Peterlin, Karmen Stanič, Ignasi Méndez and Andrej Strojnik

    Radiation Oncology 2017 12:93

    Published on: 2 June 2017

  11. Research

    Radiation-related lymphopenia is associated with spleen irradiation dose during radiotherapy in patients with hepatocellular carcinoma

    The decrease in peripheral blood lymphocytes induced by radiation lessens the antitumour effect of the immune response, which might cause immunosuppression. We aimed to investigate the correlation between the ...

    Jing Liu, Qianqian Zhao, Weiye Deng, Jie Lu, Xiaoqing Xu, Renben Wang, Xia Li and Jinbo Yue

    Radiation Oncology 2017 12:90

    Published on: 30 May 2017

  12. Research

    Clinical implementation of a knowledge based planning tool for prostate VMAT

    A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV...

    Richard Powis, Andrew Bird, Matthew Brennan, Susan Hinks, Hannah Newman, Katie Reed, John Sage and Gareth Webster

    Radiation Oncology 2017 12:81

    Published on: 8 May 2017

  13. Research

    Dose tracking assessment for image-guided radiotherapy of the prostate bed and the impact on clinical workflow

    The cumulative dose was compared with the planned dose among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of the prostate bed. Moreover, we investigated the feasibility of adding...

    Lucia Clara Orlandini, Marianna Coppola, Christian Fulcheri, Luna Cernusco, Pei Wang and Luca Cionini

    Radiation Oncology 2017 12:78

    Published on: 28 April 2017

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