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  1. Spinal radiosurgery is a quickly evolving technique in the radiotherapy and neurosurgical communities. However, the methods of spine radiosurgery have not been standardized. This article describes the results ...

    Authors: Matthias Guckenberger, Reinhart A Sweeney, John C Flickinger, Peter C Gerszten, Ronald Kersh, Jason Sheehan and Arjun Sahgal
    Citation: Radiation Oncology 2011 6:172
  2. It has been postulated that ionizing radiation induces breast cancers among atomic bomb (A-bomb) survivors. We have reported a higher incidence of HER2 and C-MYC oncogene amplification in breast cancers from A-bo...

    Authors: Masahiro Oikawa, Koh-ichiro Yoshiura, Hisayoshi Kondo, Shiro Miura, Takeshi Nagayasu and Masahiro Nakashima
    Citation: Radiation Oncology 2011 6:168
  3. Radiotherapy (RT) remains an effective treatment in patients with acromegaly refractory to medical and/or surgical interventions, with durable tumor control and biochemical remission; however, there are still ...

    Authors: Giuseppe Minniti, Claudia Scaringi and Riccardo Maurizi Enrici
    Citation: Radiation Oncology 2011 6:167
  4. Brain metastases occur in 30-50% of Non-small cell lung cancer (NSCLC) patients and confer a worse prognosis and quality of life. These patients are usually treated with Whole-brain radiotherapy (WBRT) followe...

    Authors: Oscar Arrieta, Cynthia Villarreal-Garza, Jesús Zamora, Mónika Blake-Cerda, María D de la Mata, Diego G Zavala, Saé Muñiz-Hernández and Jaime de la Garza
    Citation: Radiation Oncology 2011 6:166
  5. [18F]FAZA is a PET biomarker with great potential for imaging tumor hypoxia. Aim of our study was to compare [18F]FAZA uptake in mice with subcutaneous exogenous CT26 colon carcinomas and endogenous polyoma middl...

    Authors: Florian C Maier, Manfred Kneilling, Gerald Reischl, Funda Cay, Daniel Bukala, Andreas Schmid, Martin S Judenhofer, Martin Röcken, Hans-Jürgen Machulla and Bernd J Pichler
    Citation: Radiation Oncology 2011 6:165
  6. The Monte Carlo code GEANT4 was used to implement first steps towards a treatment planning program for fast-neutron therapy at the FRM II research reactor in Garching, Germany. Depth dose curves were calculate...

    Authors: Sylvia Garny, Werner Rühm, Maria Zankl, Franz M Wagner and Herwig G Paretzke
    Citation: Radiation Oncology 2011 6:163
  7. to evaluate activity and toxicity of a sequential treatment in advanced, non metastatic, mostly unresectable, head and neck squamous cell carcinoma.

    Authors: Stefano Pergolizzi, Anna Santacaterina, Barbara Adamo, Tindara Franchina, Nerina Denaro, Pina Ferraro, Giusy RR Ricciardi, Nicola Settineri and Vincenzo Adamo
    Citation: Radiation Oncology 2011 6:162
  8. Neoadjuvant chemoradiotherapy is the treatment of choice in advanced rectal cancer, even though there are many patients who will not benefit from it. There are still no effective methods for predicting which p...

    Authors: Chiara Molinari, Michela Ballardini, Nazario Teodorani, Massimo Giannini, Wainer Zoli, Ermanno Emiliani, Enrico Lucci, Alessandro Passardi, Paola Rosetti, Luca Saragoni, Massimo Guidoboni, Dino Amadori and Daniele Calistri
    Citation: Radiation Oncology 2011 6:161
  9. Brain metastases afflict approximately half of patients with metastatic melanoma (MM) and small cell lung cancer (SCLC) and represent the direct cause of death in 60 to 70% of those affected. Standard of care ...

    Authors: Kirtesh Patel, Nicole A Doudican, Peter B Schiff and Seth J Orlow
    Citation: Radiation Oncology 2011 6:160
  10. The quality of the interdisciplinary interface in oncological treatment between surgery, pathology and radiotherapy is mainly dependent on reliable anatomical three-dimensional (3D) allocation of specimen and ...

    Authors: Harald Essig, Majeed Rana, Andreas Meyer, André M Eckardt, Horst Kokemueller, Constantin von See, Daniel Lindhorst, Frank Tavassol, Martin Ruecker and Nils-Claudius Gellrich
    Citation: Radiation Oncology 2011 6:159
  11. To assess the accuracy of patient repositioning and clinical outcomes of frameless stereotactic radiosurgery (SRS) for brain metastases using a stereotactic mask fixation system.

    Authors: Giuseppe Minniti, Claudia Scaringi, Enrico Clarke, Maurizio Valeriani, Mattia Osti and Riccardo Maurizi Enrici
    Citation: Radiation Oncology 2011 6:158
  12. Stereotactic radiosurgery/radiotherapy procedures are known to deliver a very high dose per fraction, and thus, the corresponding peripheral dose could be a limiting factor for the long term surviving patients...

    Authors: Vassiliki Vlachopoulou, Christos Antypas, Harry Delis, Argyrios Tzouras, Nikolaos Salvaras, Dimitrios Kardamakis and George Panayiotakis
    Citation: Radiation Oncology 2011 6:157
  13. Radiation therapy is routinely prescribed for high-grade malignant gliomas. However, the efficacy of this therapeutic modality is often limited by the occurrence of radioresistance, reflected as a diminished s...

    Authors: Carlos A Fedrigo, Ivana Grivicich, Daniel P Schunemann, Ivan M Chemale, Daiane dos Santos, Thais Jacovas, Patryck S Boschetti, Geraldo P Jotz, Aroldo Braga Filho and Adriana B da Rocha
    Citation: Radiation Oncology 2011 6:156
  14. To report the clinical outcome after a Single Shot 3D-CRT PBI (SSPBI) in breast cancer patients after conservative surgery (ClinicalTrials.gov Identifier: NCT01316328).

    Authors: Paola Pinnarò, Stefano Arcangeli, Carolina Giordano, Giorgio Arcangeli, Fabrizio Ambesi Impiombato, Valentina Pinzi, Giuseppe Iaccarino, Antonella Soriani, Valeria Landoni and Lidia Strigari
    Citation: Radiation Oncology 2011 6:155
  15. Although 3D-conformal accelerated partial breast irradiation (APBI) is widely used, several questions still remain such as what are the optimal treatment planning modalities. Indeed, some patients may have an ...

    Authors: Mohamed El Nemr, Steve Heymann, Rodolfe Verstraet, Bruno Biron, Fares Azoury, Hugo Marsiglia and Céline Bourgier
    Citation: Radiation Oncology 2011 6:154
  16. In order to define new prognostic subgroups in patients with glioblastoma a miRNA screen (> 1000 miRNAs) from paraffin tissues followed by a bio-mathematical analysis was performed.

    Authors: Maximilian Niyazi, Franz Zehentmayr, Olivier M Niemöller, Sabina Eigenbrod, Hans Kretzschmar, Klaus Schulze-Osthoff, Jörg-Christian Tonn, Mike Atkinson, Simone Mörtl and Claus Belka
    Citation: Radiation Oncology 2011 6:153
  17. Frequently, three-dimensional (3D) conformal beams are used in lung cancer stereotactic body radiotherapy (SBRT). Recently, volumetric modulated arc therapy (VMAT) was introduced as a new treatment modality. V...

    Authors: Geoffrey G Zhang, Lichung Ku, Thomas J Dilling, Craig W Stevens, Ray R Zhang, Weiqi Li and Vladimir Feygelman
    Citation: Radiation Oncology 2011 6:152
  18. To evaluate the cardiac toxicity of radiotherapy (RT) in breast cancer (BC) patients employing myocardial perfusion imaging (MPI) with Tc-99 m Tetrofosmin - single photon emission computer tomography (T-SPECT).

    Authors: Chrissa Sioka, Thomas Exarchopoulos, Ifigenia Tasiou, Eftychia Tzima, Nikolaos Fotou, Antonio Capizzello, Vasilios Ragos, Periklis Tsekeris and Andreas Fotopoulos
    Citation: Radiation Oncology 2011 6:151
  19. To evaluate prognostic factors in salvage radiotherapy (RT) for patients with pre-RT prostate-specific antigen (PSA) < 1.0 ng/ml.

    Authors: Rei Umezawa, Hisanori Ariga, Yoshihiro Ogawa, Keiichi Jingu, Haruo Matsushita, Ken Takeda, Keisuke Fujimoto, Toru Sakayauchi, Toshiyuki Sugawara, Masaki Kubozono, Kakutaro Narazaki, Eiji Shimizu, Yoshihiro Takai and Shogo Yamada
    Citation: Radiation Oncology 2011 6:150
  20. To investigate toxicity and efficacy in high-risk malignant salivary gland tumors (MSGT) of the head and neck. Local control in R2-resected adenoid cystic carcinoma was already improved with a combination of I...

    Authors: Alexandra D Jensen, Anna V Nikoghosyan, Swantje Ecker, Malte Ellerbrock, Jürgen Debus, Klaus K Herfarth and Marc W Münter
    Citation: Radiation Oncology 2011 6:149
  21. Vaults are evolutionary highly conserved ribonucleoproteins particles with a hollow barrel-like structure. The main component of vaults represents the 110 kDa major vault protein (MVP), whereas two minor vault...

    Authors: Pedro C Lara, Martin Pruschy, Martina Zimmermann and Luis Alberto Henríquez-Hernández
    Citation: Radiation Oncology 2011 6:148
  22. To compare volumetric-modulated arc therapy plans with conventional radiation therapy (3D-CRT) plans in pancreatic and bile duct cancers, especially for bilateral kidney preservation.

    Authors: Sabine Vieillot, David Azria, Olivier Riou, Carmen Llacer Moscardo, Jean-Bernard Dubois, Norbert Aillères and Pascal Fenoglietto
    Citation: Radiation Oncology 2011 6:147
  23. The retroperitoneal margin is a common site of positive surgical margins in patients with resectable pancreatic cancer. Preoperative margin-intensive therapy (MIT) involves delivery of a single high dose of ab...

    Authors: John H Heinzerling, Ross Bland, John C Mansour, Roderich E Schwarz, Ezequiel Ramirez, Chuxiong Ding, Ramzi Abdulrahman, Thomas P Boike, Timothy Solberg, Robert D Timmerman and Jeffrey J Meyer
    Citation: Radiation Oncology 2011 6:146
  24. Image-guided radiotherapy (IGRT) increases the accuracy of treatment delivery through daily target localisation. We report on toxicity symptoms experienced during radiotherapy treatment, with and without IGRT ...

    Authors: Suki Gill, Jessica Thomas, Chris Fox, Tomas Kron, Aldo Rolfo, Mary Leahy, Sarat Chander, Scott Williams, Keen Hun Tai, Gillian M Duchesne and Farshad Foroudi
    Citation: Radiation Oncology 2011 6:145
  25. Prostate cancer (PrCa) displays resistance to radiotherapy (RT) and requires radiotherapy dose escalation which is associated with greater toxicity. This highlights a need to develop radiation sensitizers to i...

    Authors: Ayesha Rashid, Caiqiong Liu, Toran Sanli, Evangelia Tsiani, Gurmit Singh, Robert G Bristow, Ian Dayes, Himu Lukka, James Wright and Theodoros Tsakiridis
    Citation: Radiation Oncology 2011 6:144
  26. Spinal cord stimulators (SCS) are a well-recognised treatment modality in the management of a number of chronic neuropathic pain conditions, particularly failed back syndrome and radiculopathies. The implantab...

    Authors: Lorraine Walsh, Daipayan Guha, Thomas G Purdie, Philippe Bedard, Alexandra Easson, Fei-Fei Liu and Mojgan Hodaie
    Citation: Radiation Oncology 2011 6:143
  27. To evaluate the daily total error shift patterns on post-prostatectomy patients undergoing image guided radiotherapy (IGRT) with a diagnostic quality computer tomography (CT) on rails system.

    Authors: Ronaldo Cavalieri, Hiram A Gay, Jingxia Liu, Maria C Ferreira, Helvecio C Mota, Claudio H Sibata and Ron R Allison
    Citation: Radiation Oncology 2011 6:142
  28. To analyze the differences between the intensity-modulated radiotherapy (IMRT), single/partial-arc volumetric modulated arc therapy (SA/PA-VMAT) techniques in treatment planning for locally advanced lung cancer.

    Authors: Xiaoqin Jiang, Tao Li, Yongmei Liu, Lin Zhou, Yong Xu, Xiaojuan Zhou and Youling Gong
    Citation: Radiation Oncology 2011 6:140
  29. Laser acceleration of protons and heavy ions may in the future be used in radiation therapy. Laser-driven particle beams are pulsed and ultra high dose rates of >109 Gy s-1may be achieved. Here we compare the rad...

    Authors: Susanne Auer, Volker Hable, Christoph Greubel, Guido A Drexler, Thomas E Schmid, Claus Belka, Günther Dollinger and Anna A Friedl
    Citation: Radiation Oncology 2011 6:139
  30. Chest wall injury after stereotactic radiotherapy (SRT) for primary lung cancer has recently been reported. However, its detailed imaging findings are not clarified. So this study aimed to fully characterize t...

    Authors: Atsushi Nambu, Hiroshi Onishi, Shinichi Aoki, Tsuyota Koshiishi, Kengo Kuriyama, Takafumi Komiyama, Kan Marino, Masayuki Araya, Ryo Saito, Lichto Tominaga, Yoshiyasu Maehata, Eiichi Sawada and Tsutomu Araki
    Citation: Radiation Oncology 2011 6:137
  31. Oral cavity cancers (ORC) are the most common cancers, and standard treatment is radical surgery with postoperative radiotherapy. However, locoregional failure remains a major problem, indicating radioresistan...

    Authors: Chien-Yu Lin, Ting-Yang Lin, Hung-Ming Wang, Shiang-Fu Huang, Kang-Hsing Fan, Chun-Ta Liao, I-How Chen, Li-Yu Lee, Yen-Liang Li, Yin-Ju Chen, Ann-Joy Cheng and Joseph T Chang
    Citation: Radiation Oncology 2011 6:136
  32. We aimed to assess outcomes of patients with anal cancer who underwent intensity-modulated radiotherapy (IMRT) and received less than 1.80 Gy/day.

    Authors: Jason A Call, Michael G Haddock, J Fernando Quevedo, David W Larson and Robert C Miller
    Citation: Radiation Oncology 2011 6:134
  33. Mitochondrial DNA (mtDNA) alterations, including mtDNA copy number and mtDNA 4977 bp common deletion (CD), are key indicators of irradiation-induced damage. The relationship between total body irradiation (TBI...

    Authors: Quan Wen, Yide Hu, Fuyun Ji and Guisheng Qian
    Citation: Radiation Oncology 2011 6:133
  34. Sublethal photon irradiation was recently suspected to increase tumor cell motility and promote locoregional recurrence of disease. This study was set up to describe mechanisms underlying increased glioma cell...

    Authors: Stefan Rieken, Daniel Habermehl, Angela Mohr, Lena Wuerth, Katja Lindel, Klaus Weber, Jürgen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2011 6:132
  35. Although the nodal ratio (NR) has been recognized as a prognostic factor in breast cancer, its clinical implication in patients with 1-3 positive nodes (N1) remains unclear. Here, we evaluated the prognostic v...

    Authors: Tae Jin Han, Eun Young Kang, Wan Jeon, Sung-Won Kim, Jee Hyun Kim, Yu Jung Kim, So Yeon Park, Jae Sung Kim and In Ah Kim
    Citation: Radiation Oncology 2011 6:131
  36. The aim was to determine the incidence of seed migration not only to the chest, but also to the abdomen and pelvis after transperineal interstitial prostate brachytherapy with loose 125I seeds.

    Authors: Akitomo Sugawara, Jun Nakashima, Etsuo Kunieda, Hirohiko Nagata, Ryuichi Mizuno, Satoshi Seki, Yutaka Shiraishi, Ryuichi Kouta, Mototsugu Oya and Naoyuki Shigematsu
    Citation: Radiation Oncology 2011 6:130
  37. A new-generation low-energy linear accelerator (UNIQUE) was introduced in the clinical arena during 2009 by Varian Medical Systems. The world's first UNIQUE was installed at Oncology Institute of Southern Swit...

    Authors: Alessandro Clivio, Giorgia Nicolini, Eugenio Vanetti, Antonella Fogliata and Luca Cozzi
    Citation: Radiation Oncology 2011 6:129
  38. Temporal lobe necrosis (TLN) is the most debilitating late-stage complication after radiation therapy in patients with nasopharyngeal cancer (NPC). The bilateral temporal lobes are inevitably encompassed in th...

    Authors: Jing Chen, Meera Dassarath, Zhongyuan Yin, Hongli Liu, Kunyu Yang and Gang Wu
    Citation: Radiation Oncology 2011 6:128
  39. Postoperative chemoradiation as per Intergroup-0116 trial ("Macdonald regimen") is considered standard for completely resected high risk gastric cancer. However, many concerns remain with regards to the toxici...

    Authors: Yulia Kundel, Ofer Purim, Efraim Idelevich, Konstantin Lavrenkov, Sofia Man, Svetlana Kovel, Natalia Karminsky, Raphael M Pfeffer, Bella Nisenbaum, Eyal Fenig, Aaron Sulkes and Baruch Brenner
    Citation: Radiation Oncology 2011 6:127
  40. The role of adjuvant chemoradiation therapy for ampullary carcinoma is unknown. Previous literature suggests that certain populations with high risk factors for recurrence may benefit from adjuvant chemoradiat...

    Authors: Amol K Narang, Robert C Miller, Charles C Hsu, Sumita Bhatia, Timothy M Pawlik, Dan Laheru, Ralph H Hruban, Jessica Zhou, Jordan M Winter, Michael G Haddock, John H Donohue, Richard D Schulick, Christopher L Wolfgang, John L Cameron and Joseph M Herman
    Citation: Radiation Oncology 2011 6:126
  41. The aim of the present study was to evaluate the recovery potential of the parotid glands after using either 3D-conformal-radiotherapy (3D-CRT) or intensity-modulated radiotherapy (IMRT) by sparing one single ...

    Authors: Jeremias Hey, Juergen Setz, Reinhard Gerlach, Martin Janich, Guido Hildebrandt, Dirk Vordermark, Christian R Gernhardt and Thomas Kuhnt
    Citation: Radiation Oncology 2011 6:125
  42. To explore possible improvement in the treatment of locally advanced pancreatic carcinoma (LAPC) we performed a randomized, non-comparative phase II study evaluating docetaxel - plus either daily continuous 5 ...

    Authors: Lucie Oberic, Frédéric Viret, Charlotte Baey, Marc Ychou, Jaafar Bennouna, Antoine Adenis, Didier Peiffert, Françoise Mornex, Jean-Pierre Pignon, Patrice Celier, Jocelyne Berille and Michel Ducreux
    Citation: Radiation Oncology 2011 6:124
  43. Several investigations have recently suggested the existence of a correlation between the dose received by the penile bulb (PB) and the risk of erectile dysfunction (ED) after radical radiotherapy for clinical...

    Authors: Lucia Perna, Cesare Cozzarini, Eleonora Maggiulli, Gianni Fellin, Tiziana Rancati, Riccardo Valdagni, Vittorio Vavassori, Sergio Villa and Claudio Fiorino
    Citation: Radiation Oncology 2011 6:123

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