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Radiation Physics

Section edited by Christoph Bert and Katia Parodi

The Radiation Physics section aims at providing a platform for medical physics research and applications in radiation oncology. This includes innovative developments in the application of physical sciences to radiation oncology, spanning the broad range of advanced beam delivery and imaging, dosimetry, computation, modeling and data processing. Contributions proposing innovative methodological approaches or presenting original assessment on the clinical relevance of new technologies are welcome. Space is also given to review contributions on timely topics, as well as invited key reviews from renowned experts. Hence, the Radiation Physics section addresses contemporary cutting-edge research and methodological advancements for improved clinical practice, as well as reviews of relevant medical physics issues in radiation oncology, offering a fast review process and broad outreach.

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  1. The purpose of this study is to investigate the dosimetric advantages of volumetric modulated arc therapy (VMAT) in the treatment of intraocular cancer by comparing it directly with three-dimensional conformal...

    Authors: Zhenxiang Deng, Lanxiao Shen, Xiaomin Zheng, Yongqiang Zhou, Jinling Yi, Ce Han, Congying Xie and Xiance Jin
    Citation: Radiation Oncology 2017 12:83
  2. A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV...

    Authors: Richard Powis, Andrew Bird, Matthew Brennan, Susan Hinks, Hannah Newman, Katie Reed, John Sage and Gareth Webster
    Citation: Radiation Oncology 2017 12:81
  3. Patients with glioblastoma multiforme (GBM) require radiotherapy as part of definitive management. Our institution has adopted the use of volumetric arc therapy (VMAT) due to superior sparing of the adjacent o...

    Authors: Tina Marie Briere, Mary Frances McAleer, Lawrence B. Levy and James N. Yang
    Citation: Radiation Oncology 2017 12:79
  4. The cumulative dose was compared with the planned dose among fourteen patients undergoing image-guided, intensity-modulated radiotherapy of the prostate bed. Moreover, we investigated the feasibility of adding...

    Authors: Lucia Clara Orlandini, Marianna Coppola, Christian Fulcheri, Luna Cernusco, Pei Wang and Luca Cionini
    Citation: Radiation Oncology 2017 12:78
  5. The aim of this study was to compare radiotherapy plans for Stage I-II nasal natural killer/T-cell lymphoma (NNKTL) using helical tomotherapy (HT), volumetric-modulated arc therapy (VMAT), Fixed-Field intensit...

    Authors: Xianfeng Liu, Erliang Huang, Ying Wang, Yanan He, Huanli Luo, Mingsong Zhong, Da Qiu, Chao Li, Han Yang, Guanglei He, Juan Zhou and Fu Jin
    Citation: Radiation Oncology 2017 12:76
  6. To evaluate a knowledge based planning model for RapidPlan (RP) generated for advanced head and neck cancer (HNC) patient treatments, as well its ability to possibly improve the clinical plan quality. The stab...

    Authors: A. Fogliata, G. Reggiori, A. Stravato, F. Lobefalo, C. Franzese, D. Franceschini, S. Tomatis, P. Mancosu, M. Scorsetti and L. Cozzi
    Citation: Radiation Oncology 2017 12:73
  7. It is useful to predict planned dosimetry and determine the eligibility of a liver cancer patient for SBRT treatment using knowledge based planning (KBP). We compare the predictive accuracy using the overlap v...

    Authors: Angelia Tran, Kaley Woods, Dan Nguyen, Victoria Y. Yu, Tianye Niu, Minsong Cao, Percy Lee and Ke Sheng
    Citation: Radiation Oncology 2017 12:70
  8. Motion monitoring is essential when treating non-static tumours with pencil beam scanned protons. 4D medical imaging typically relies on the detected body surface displacement, considered as a surrogate of the...

    Authors: Giovanni Fattori, Sairos Safai, Pablo Fernández Carmona, Marta Peroni, Rosalind Perrin, Damien Charles Weber and Antony John Lomax
    Citation: Radiation Oncology 2017 12:63
  9. The range shifter (RS) is used to treat shallow tumors for a proton pencil beam scanning system (PBS). Adding RS certainly complicates the commissioning of the treatment planning system (TPS) because the spot ...

    Authors: Jiajian Shen, Jarrod M. Lentz, Yanle Hu, Wei Liu, Danairis Hernandez Morales, Joshua B. Stoker and Martin Bues
    Citation: Radiation Oncology 2017 12:52
  10. The aim of this study was to assess the dose to the humeral head planning risk volume with the currently used high tangential fields (HTF) and compare different planning techniques for breast radiotherapy incl...

    Authors: Kathrin Surmann, Jorien van der Leer, Tammy Branje, Maurice van der Sangen, Maarten van Lieshout and Coen W. Hurkmans
    Citation: Radiation Oncology 2017 12:22
  11. Intensity-modulated proton therapy (IMPT), non-coplanar 4π intensity-modulated radiation therapy (IMRT), and volumetric-modulated arc therapy (VMAT) represent the most advanced treatment methods based on heavy...

    Authors: Angelia Tran, Jingjing Zhang, Kaley Woods, Victoria Yu, Dan Nguyen, Gary Gustafson, Lane Rosen and Ke Sheng
    Citation: Radiation Oncology 2017 12:10
  12. The purpose of this study was to use 4-dimensional-computed tomography (4D-CT) to evaluate respiration-induced liver motion magnitude and influencing factors in patients with intrahepatic tumors undergoing abd...

    Authors: Yong Hu, Yong-Kang Zhou, Yi-Xing Chen and Zhao-Chong Zeng
    Citation: Radiation Oncology 2017 12:9
  13. Modern radiotherapy offers various possibilities for image guided verification of patient positioning. Different clinically relevant IGRT (image guided radiotherapy) scenarios were considered with regard to th...

    Authors: Katharina Bell, Marina Heitfeld, Norbert Licht, Christian Rübe and Yvonne Dzierma
    Citation: Radiation Oncology 2017 12:7
  14. To assess the accuracy and precision of a fully integrated pilot installation of stereoscopic X-ray imaging and kV-CBCT for automatic couch positioning in stereotactic radiotherapy of intracranial tumors. Posi...

    Authors: Barbara Zollner, Christian Heinz, Sabrina Pitzler, Farkhad Manapov, Steffi Kantz, Maya Christine Rottler, Maximilian Niyazi, Ute Ganswindt, Claus Belka and Hendrik Ballhausen
    Citation: Radiation Oncology 2016 11:158
  15. The purpose of this study is to find the optimal planning settings for prostate SABR-VMAT for high-risk prostate cancer patients irradiated to prostate only (PO) or prostate and pelvic lymph nodes (PPLN).

    Authors: Sarah O. S. Osman, Prakash Jeevanandam, Nithya Kanakavelu, Denise M. Irvine, Ciara A. Lyons, Suneil Jain, Alan R. Hounsell and Conor K. McGarry
    Citation: Radiation Oncology 2016 11:155
  16. Large tumor motion often leads to larger treatment volumes, especially the lung tumor located in lower lobe and adhered to chest wall or diaphragm. The purpose of this work is to investigate the impacts of pla...

    Authors: Yi Li, Jing-lu Ma, Xin Chen, Feng-wen Tang and Xiao-zhi Zhang
    Citation: Radiation Oncology 2016 11:152
  17. Evaluation of set up error detection by a transperineal ultrasound in comparison with a cone beam CT (CBCT) based system in external beam radiation therapy (EBRT) of prostate cancer.

    Authors: Anne Richter, Bülent Polat, Ingulf Lawrenz, Stefan Weick, Otto Sauer, Michael Flentje and Frederick Mantel
    Citation: Radiation Oncology 2016 11:147
  18. In volumetric modulated arc therapy (VMAT), gantry angles, dose rate and the MLC positions vary with the radiation delivery. The quality assurance (QA) system should be able to catch the planning and machine e...

    Authors: Bin Liang, Bo Liu, Fugen Zhou, Fang-fang Yin and Qiuwen Wu
    Citation: Radiation Oncology 2016 11:146
  19. Derivation of dose-volume correlated with toxicity for multi-modal treatments can be difficult due to the perceived need for voxel-by-voxel dose accumulation. With data available for a single-institution cohor...

    Authors: Calyn R. Moulton, Michael J. House, Victoria Lye, Colin I. Tang, Michele Krawiec, David J. Joseph, James W. Denham and Martin A. Ebert
    Citation: Radiation Oncology 2016 11:144
  20. There is a potential for adverse cardiovascular effects in long-term breast cancer survivors following adjuvant radiotherapy (RT). For this purpose, the deep inspiration breath-hold technique (DIBH) has been i...

    Authors: S. Schönecker, F. Walter, P. Freislederer, C. Marisch, H. Scheithauer, N. Harbeck, S. Corradini and C. Belka
    Citation: Radiation Oncology 2016 11:143
  21. The aim of this study was to analyze differences in couch shifts (setup errors) resulting from image registration of different CT datasets with free breathing cone beam CTs (FB-CBCT). As well automatic as manu...

    Authors: Markus Oechsner, Barbara Chizzali, Michal Devecka, Stephanie Elisabeth Combs, Jan Jakob Wilkens and Marciana Nona Duma
    Citation: Radiation Oncology 2016 11:142
  22. The purpose of this study is to evaluate the dosimetric benefits of a proton arc technique for treating tumors of the para-aortic lymph nodes (PALN).

    Authors: Jeong-Eun Rah, Gwe-Ya Kim, Do Hoon Oh, Tae Hyun Kim, Jong Won Kim, Dae Yong Kim, Sung Yong Park and Dongho Shin
    Citation: Radiation Oncology 2016 11:140
  23. The efficacy of radiation therapy treatments for pancreatic cancer is compromised by abdominal motion which limits the spatial accuracy for dose delivery - especially for particles. In this work we investigate...

    Authors: Julian Steitz, Patrick Naumann, Silke Ulrich, Matthias F. Haefner, Florian Sterzing, Uwe Oelfke and Mark Bangert
    Citation: Radiation Oncology 2016 11:134
  24. The purpose of this study is to evaluate the dosimetric uncertainty associated with Gafchromic™ (EBT3) films and establish a practical and efficient film dosimetry protocol for Stereotactic Radiosurgery (SRS) ...

    Authors: Ning Wen, Siming Lu, Jinkoo Kim, Yujiao Qin, Yimei Huang, Bo Zhao, Chang Liu and Indrin J. Chetty
    Citation: Radiation Oncology 2016 11:132
  25. Comparing radiation treatment plans to ascertain the optimal intensity-modulated radiation technique for low-risk prostate cancer.

    Authors: Sergiu Scobioala, Christopher Kittel, Nicolas Wissmann, Uwe Haverkamp, Mohammed Channaoui, Omar Habibeh, Khaled Elsayad and Hans Theodor Eich
    Citation: Radiation Oncology 2016 11:128
  26. To compare retrospectively generated gated plans to conventional internal target volume (ITV)-based plans and to evaluate whether gated radiotherapy provides clinically relevant dosimetric improvements to orga...

    Authors: Joshua Kim, Qixue Wu, Bo Zhao, Ning Wen, Munther Ajlouni, Benjamin Movsas and Indrin J. Chetty
    Citation: Radiation Oncology 2016 11:125
  27. Deformable image registration (DIR) is a key component in many radiotherapy applications. However, often resulting deformations are not satisfying, since varying deformation properties of different anatomical ...

    Authors: Lars König, Alexander Derksen, Nils Papenberg and Benjamin Haas
    Citation: Radiation Oncology 2016 11:122
  28. For breast cancer patients who require electron boost energies between 6 and 9 MeV, an energy degraders (ED) in the 9 MeV beamline was specially designed and manufactured to increase the skin dose of 6 MeV and...

    Authors: Jong In Park, Sung Whan Ha, Jung-in Kim, Hyunseok Lee, Jaegi Lee, Il Han Kim and Sung-Joon Ye
    Citation: Radiation Oncology 2016 11:112
  29. The aim of the study was to compare the two irradiation modes with (FF) and without flattening filter (FFF) for three different treatment techniques for simultaneous integrated boost radiation therapy of patie...

    Authors: Johannes Maier, Bernadette Knott, Manuel Maerz, Rainer Loeschel, Oliver Koelbl and Barbara Dobler
    Citation: Radiation Oncology 2016 11:111
  30. The development of a dose-volume-histogram (DVH) estimation model for knowledge-based planning is very time-consuming and it could be inefficient if it was only used for similar upcoming cases as supposed. It ...

    Authors: Hao Wu, Fan Jiang, Haizhen Yue, Hui Zhang, Kun Wang and Yibao Zhang
    Citation: Radiation Oncology 2016 11:108
  31. The aim of this study is to investigate the performance and limitations of a real-time transit electronic portal imaging device (EPID) dosimetry system for error detection during dynamic intensity modulated ra...

    Authors: Todsaporn Fuangrod, Peter B. Greer, Henry C. Woodruff, John Simpson, Shashank Bhatia, Benjamin Zwan, Timothy A. vanBeek, Boyd M.C. McCurdy and Richard H. Middleton
    Citation: Radiation Oncology 2016 11:106
  32. Fiducial markers are the superior method to compensate for interfractional motion in liver SBRT. However this method is invasive and thereby limits its application range. In this retrospective study, the compe...

    Authors: Christian Heinz, Sabine Gerum, Philipp Freislederer, Ute Ganswindt, Falk Roeder, Stefanie Corradini, Claus Belka and Maximilian Niyazi
    Citation: Radiation Oncology 2016 11:88
  33. A challenge preventing routine clinical implementation of Monte Carlo (MC)-based lung SBRT is the difficulty of reinterpreting historical outcome data calculated with inaccurate dose algorithms, because the ta...

    Authors: Dandan Zheng, Xiaofeng Zhu, Qinghui Zhang, Xiaoying Liang, Weining Zhen, Chi Lin, Vivek Verma, Shuo Wang, Andrew Wahl, Yu Lei, Sumin Zhou and Chi Zhang
    Citation: Radiation Oncology 2016 11:83
  34. A sweeping beam technique for total body irradiation in standard treatment rooms and for standard linear accelerators (linacs) is introduced, which does not require any accessory attached to the linac. Lung sh...

    Authors: Petra M. Härtl, Marius Treutwein, Matthias G. Hautmann, Manuel März, Fabian Pohl, Oliver Kölbl and Barbara Dobler
    Citation: Radiation Oncology 2016 11:81
  35. The effects of spinal implants on dose distribution have been studied for conformal treatment plans. However, the dosimetric impact of spinal implants in stereotactic body radiotherapy (SBRT) treatments has no...

    Authors: Gozde Yazici, Sezin Yuce Sari, Fazli Yagiz Yedekci, Altug Yucekul, Sumerya Duru Birgi, Gokhan Demirkiran, Melis Gultekin, Pervin Hurmuz, Muharrem Yazici, Gokhan Ozyigit and Mustafa Cengiz
    Citation: Radiation Oncology 2016 11:71
  36. Dynamic Wave Arc (DWA) is a clinical approach designed to maximize the versatility of Vero SBRT system by synchronizing the gantry-ring noncoplanar movement with D-MLC optimization. The purpose of this study w...

    Authors: Manuela Burghelea, Dirk Verellen, Kenneth Poels, Cecilia Hung, Mitsuhiro Nakamura, Jennifer Dhont, Thierry Gevaert, Robbe Van den Begin, Christine Collen, Yukinori Matsuo, Takahiro Kishi, Viorica Simon, Masahiro Hiraoka and Mark de Ridder
    Citation: Radiation Oncology 2016 11:63
  37. During a fraction of external beam radiotherapy for prostate cancer, a mismatch between target volume and dose coverage may accumulate over time due to intra-fraction motion. One way to remove the residual err...

    Authors: Hendrik Ballhausen, Ute Ganswindt, Claus Belka and Minglun Li
    Citation: Radiation Oncology 2016 11:49

    The Data Descriptor to this article has been published in Scientific Data 2019 6:269

  38. Intraoperative electron radiotherapy (IOERT) is a highly selective radiotherapy technique which aims to treat restricted anatomic volumes during oncological surgery and is now the subject of intense re-evaluat...

    Authors: Juan López-Tarjuelo, Virginia Morillo-Macías, Ana Bouché-Babiloni, Enrique Boldó-Roda, Rafael Lozoya-Albacar and Carlos Ferrer-Albiach
    Citation: Radiation Oncology 2016 11:41
  39. Unscheduled accelerator downtime can negatively impact the quality of life of patients during their struggle against cancer. Currently digital data accumulated in the accelerator system is not being exploited ...

    Authors: Charles M. Able, Alan H. Baydush, Callistus Nguyen, Jacob Gersh, Alois Ndlovu, Igor Rebo, Jeremy Booth, Mario Perez, Benjamin Sintay and Michael T. Munley
    Citation: Radiation Oncology 2016 11:36
  40. Through the Monte Carlo (MC) simulation of 6 and 10 MV flattening-filter-free (FFF) beams from Varian TrueBeam accelerator, this study aims to find the best incident electron distribution for further studying ...

    Authors: Zhongsu Feng, Haizhen Yue, Yibao Zhang, Hao Wu, Jinsheng Cheng and Xu Su
    Citation: Radiation Oncology 2016 11:30
  41. Accelerated partial breast irradiation (APBI) is a new breast treatment modality aiming to reduce treatment time using hypo fractionation. Compared to conventional whole breast irradiation that takes 5 to 6 we...

    Authors: Erwann Rault, Thomas Lacornerie, Hong-Phuong Dang, Frederik Crop, Eric Lartigau, Nick Reynaert and David Pasquier
    Citation: Radiation Oncology 2016 11:29
  42. To investigate the feasibility of a novel dedicated treatment planning solution, to automatically target multiple brain metastases with a single isocenter and multiple inversely-optimized dynamic conformal arc...

    Authors: Thierry Gevaert, Femke Steenbeke, Luca Pellegri, Benedikt Engels, Nicolas Christian, Marie-Thérèse Hoornaert, Dirk Verellen, Carine Mitine and Mark De Ridder
    Citation: Radiation Oncology 2016 11:13
  43. The aim of this study is to evaluate the radiobiological impact of Acuros XB (AXB) vs. Anisotropic Analytic Algorithm (AAA) dose calculation algorithms in combined dose-volume and biological optimized IMRT pla...

    Authors: X. Liang, J. Penagaricano, D. Zheng, S. Morrill, X. Zhang, P. Corry, R. J. Griffin, E. Y. Han, M. Hardee and V. Ratanatharathom
    Citation: Radiation Oncology 2016 11:10
  44. The choice of any radiotherapy treatment plan is usually made after the evaluation of a few preliminary isodose distributions obtained from different beam configurations. Despite considerable advances in plann...

    Authors: J. C. L. Alfonso, M. A. Herrero and L. Núñez
    Citation: Radiation Oncology 2015 10:263
  45. The purpose of this study was to assess the impact on dose to the planning target volume (PTV) and organs at risk (OAR) by using four differently generated CT datasets for dose calculation in stereotactic body...

    Authors: Markus Oechsner, Leonhard Odersky, Johannes Berndt, Stephanie Elisabeth Combs, Jan Jakob Wilkens and Marciana Nona Duma
    Citation: Radiation Oncology 2015 10:249
  46. The aim of the thesis is to improve radiation plans of patients with locally advanced, unresectable pancreatic cancer by using carbon ion and proton beams.

    Authors: Constantin Dreher, Daniel Habermehl, Swantje Ecker, Stephan Brons, Rami El-Shafie, Oliver Jäkel, Jürgen Debus and Stephanie E. Combs
    Citation: Radiation Oncology 2015 10:237

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