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  1. The need for target adjustment due to respiratory motion variation and the value of carina as a motion surrogate is evaluated for locally advanced non-small-cell lung cancer.

    Authors: Nuzhat Jan, Geoffrey D. Hugo, Nitai Mukhopadhyay and Elisabeth Weiss
    Citation: Radiation Oncology 2015 10:133
  2. A multidisciplinary and multi-institutional working group applied the Failure Mode and Effects Analysis (FMEA) approach to assess the risks for patients undergoing Stereotactic Body Radiation Therapy (SBRT) tr...

    Authors: Ivan Veronese, Elena De Martin, Anna Stefania Martinotti, Maria Luisa Fumagalli, Cristina Vite, Irene Redaelli, Tiziana Malatesta, Pietro Mancosu, Giancarlo Beltramo, Laura Fariselli and Marie Claire Cantone
    Citation: Radiation Oncology 2015 10:132
  3. The mainstay of treatment in rectal cancer is neoadjuvant radio chemotherapy prior to surgery, in an attempt to downstage the tumour, allowing for more complete removal during surgery. In 40 % of cases however...

    Authors: L. Flanagan, J. Kehoe, J. Fay, O. Bacon, A.U. Lindner, E.W. Kay, J. Deasy, D.A. McNamara and J.H.M. Prehn
    Citation: Radiation Oncology 2015 10:131
  4. To assess the relationship between dosimetric parameters and the quality of life (QL) outcomes of patients with low-intermediate-risk localised prostate cancer (LPC) treated with low-dose-rate brachytherapy (L...

    Authors: Antonello Veccia, Orazio Caffo, Giovanni Fellin, Salvatore Mussari, Francesco Ziglio, Francesca Maines, Luigi Tomio and Enzo Galligioni
    Citation: Radiation Oncology 2015 10:130
  5. Radiation technology focuses on delivering the radiation as precisely as possible to the tumor, nonetheless both acute and long-term damage to surrounding normal tissue may develop. Injuries to the surrounding...

    Authors: Tonje Sønstevold, Anne Christine Johannessen and Linda Stuhr
    Citation: Radiation Oncology 2015 10:129
  6. Radical hysterectomy and radiotherapy have long been mainstays of cervical cancer treatment. Early stage cervical cancer (FIGO stage IB1–IIA) is traditionally treated using radical surgery combined with radiot...

    Authors: Jianbo Yang, Chao Ding, Tenghui Zhang, Liang Zhang, Tengfei Lv, Xiaolong Ge, Jianfeng Gong, Weiming Zhu, Ning Li and Jieshou Li
    Citation: Radiation Oncology 2015 10:128
  7. Whole brain irradiation (WBRT) either with or without resection has historically been the treatment for brain metastases from non-small cell lung cancer (NSCLC). The effect of gamma knife (GK) radiosurgery, ch...

    Authors: Ching-Heng Lin, Kuo-Hsuan Hsu, Shih-Ni Chang, Hsi-Kai Tsou, Jason Sheehan, Meei-Ling Sheu and Hung-Chuan Pan
    Citation: Radiation Oncology 2015 10:127
  8. In Japan, breast-conserving surgery with closed cavity has generally been performed for breast cancer patients, and accelerated partial breast irradiation (APBI) is considered difficult because Asian females g...

    Authors: Yuki Otani, Takayuki Nose, Takushi Dokiya, Toshiaki Saeki, Yu Kumazaki, Shuuji Asahi, Iwao Tsukiyama, Ichirou Fukuda, Hiroshi Sekine, Naoto Shikama, Takao Takahashi, Ken Yoshida, Tadayuki Kotsuma, Norikazu Masuda, Eisaku Yoden, Kazutaka Nakashima…
    Citation: Radiation Oncology 2015 10:126
  9. This study evaluates the microscopic characteristics of liver metastases from colorectal cancer (LMCRC) invasion and provides a reference for expansion from gross tumor volume (GTV) to clinical targeting volum...

    Authors: Yang Qian, Zhao-Chong Zeng, Yuan Ji and Yin-Ping Xiao
    Citation: Radiation Oncology 2015 10:125
  10. To investigate prognostic significance of clinical and pathological stages in patients with locally advanced rectal carcinoma treated with neoadjuvant chemoradiotherapy (neo-CRT) and total mesorectal excision.

    Authors: Bixiu Wen, Luning Zhang, Chengtao Wang, Rong Huang, Haihua Peng, Tian Zhang, Jun Dong, Weiwei Xiao, Zhifan Zeng, Mengzhong Liu and Yuanhong Gao
    Citation: Radiation Oncology 2015 10:124
  11. BRCC3 has been found to be aberrantly expressed in breast tumors and involved in DNA damage response. The contribution of BRCC3 to nasopharyngeal carcinoma prognosis and radiosensitivity is still unclear.

    Authors: Ziwei Tu, Bingqing Xu, Chen Qu, Yalan Tao, Chen Chen, Wenfeng Hua, Guokai Feng, Hui Chang, Zhigang Liu, Guo Li, Changbin Jiang, Wei Yi, Musheng Zeng and Yunfei Xia
    Citation: Radiation Oncology 2015 10:123
  12. The objective of this study was to evaluate a novel prostate endorectal immobilization system (EIS) for improving the delivery of hypofractionated Stereotactic Ablative Body Radiotherapy (SABR) for prostate ca...

    Authors: Alexandru Nicolae, Melanie Davidson, Harry Easton, Joelle Helou, Hima Musunuru, Andrew Loblaw and Ananth Ravi
    Citation: Radiation Oncology 2015 10:122
  13. One of the primary dose-limiting toxicities during thoracic irradiation is acute esophagitis (AE). The aim of this study is to investigate dosimetric and clinical predictors for AE grade ≥ 2 in patients treate...

    Authors: Franz Zehentmayr, Matthias Söhn, Ann-Katrin Exeli, Karl Wurstbauer, Almut Tröller, Heinz Deutschmann, Gerd Fastner, Christoph Fussl, Philipp Steininger, Manfred Kranzinger, Claus Belka, Michael Studnicka and Felix Sedlmayer
    Citation: Radiation Oncology 2015 10:121
  14. Lung cancer is the most frequent cause of cancer-related death in North America. There is wide variation between patients who are medically inoperable and those managed surgically. The use of stereotactic body...

    Authors: K. D. Kelley, D. L. Benninghoff, J. S. Stein, J. Z. Li, R. T. Byrnes, L. Potters, J. P. S. Knisely and H. D. Zinkin
    Citation: Radiation Oncology 2015 10:120
  15. Three-dimensional ultrasound (3D-US) is used in planning and treatment during external beam radiotherapy. The accuracy of the technique depends not only on the achievable image quality in clinical routine, but...

    Authors: Hendrik Ballhausen, Bianca Désirée Ballhausen, Martin Lachaine, Minglun Li, Katia Parodi, Claus Belka and Michael Reiner
    Citation: Radiation Oncology 2015 10:119
  16. Non-small cell lung cancer (NSCLC) with brain metastasis (BM) harboring an epidermal growth factor receptor (EGFR) mutation shows good response to tyrosine kinase inhibitors (TKIs). This study is to assess the...

    Authors: SongRan Liu, Bo Qiu, LiKun Chen, Fang Wang, Ying Liang, PeiQiang Cai, Li Zhang, ZhaoLin Chen, ShiLiang Liu, MengZhong Liu and Hui Liu
    Citation: Radiation Oncology 2015 10:118
  17. Elective treatment of lymph nodes in oropharyngeal cancer (OPC) has impact on both regional recurrences (RR) and risk of late side effects. This study was performed to quantify the dose-dependent impact on RR ...

    Authors: Karin Söderström, Per Nilsson, Tina Dalianis, Elisabeth Kjellén and Björn Zackrisson
    Citation: Radiation Oncology 2015 10:117
  18. Oesophageal carcinoma is a rare disease with often dismal prognosis. Despite multiple trials addressing specific issues, currently, many questions in management remain unanswered. This work aimed to specifical...

    Authors: Paul Martin Putora, Laurent Bedenne, Wilfried Budach, Wolfgang Eisterer, Ate Van Der Gaast, Robert Jäger, J. Jan B. Van Lanschot, Christophe Mariette, Annelies Schnider, Michael Stahl and Thomas Ruhstaller
    Citation: Radiation Oncology 2015 10:116
  19. The objective of this study was to compare the dose distributions of RapidArc (RA), static gantry intensity-modulated radiotherapy (IMRT), and three-dimensional conformal radiotherapy (3DCRT) as adjuvant radio...

    Authors: Tao Zhang, Zhi-Wen Liang, Jun Han, Jian-Ping Bi, Zhi-Yong Yang and Hong Ma
    Citation: Radiation Oncology 2015 10:114
  20. The purpose of this study was to evaluate treatment patterns and outcomes of stereotactic body radiotherapy (SBRT) for centrally located primary non-small cell lung cancer (NSCLC) or lung metastases from the R...

    Authors: Joanne N. Davis, Clinton Medbery, Sanjeev Sharma, John Pablo, Frank Kimsey, David Perry, Alexander Muacevic and Anand Mahadevan
    Citation: Radiation Oncology 2015 10:113
  21. Radical chemo-radiotherapy (CRT) is an effective organ-sparing treatment option for patients with locally advanced head and neck cancer (LAHNC). Despite advances in treatment for LAHNC, a significant minority ...

    Authors: Liam Welsh, Rafal Panek, Dualta McQuaid, Alex Dunlop, Maria Schmidt, Angela Riddell, Dow-Mu Koh, Simon Doran, Iain Murray, Yong Du, Sue Chua, Vibeke Hansen, Kee H. Wong, Jamie Dean, Sarah Gulliford, Shreerang Bhide…
    Citation: Radiation Oncology 2015 10:112
  22. A knowledge-based radiation therapy (KBRT) treatment planning algorithm was recently developed. The purpose of this work is to investigate how plans that are generated with the objective KBRT approach compare ...

    Authors: Obioma Nwankwo, Hana Mekdash, Dwi Seno Kuncoro Sihono, Frederik Wenz and Gerhard Glatting
    Citation: Radiation Oncology 2015 10:111
  23. Lobular carcinomas in situ (LCIS) represent 1-2% of all breast cancers. Both significance and treatment remain widely debated, as well as the possible similarities with DCIS.

    Authors: Bruno Cutuli, Brigitte De Lafontan, Youlia Kirova, Hugues Auvray, Agnes Tallet, Sandrine Avigdor, Claire Brunaud and Catherine Delva
    Citation: Radiation Oncology 2015 10:110
  24. To report our early experience with carbon ion irradiation in the treatment of gross residual or unresectable malignant peripheral nerve sheath tumors (MPNST).

    Authors: Alexandra D Jensen, Matthias Uhl, Naved Chaudhri, Klaus K Herfarth, Juergen Debus and Falk Roeder
    Citation: Radiation Oncology 2015 10:109
  25. Rhabdomyosarcoma (RMS) is the most common sarcoma in paediatric patients. A perianal site is unusual and is associated with a low cure rate. The few cases of reported perianal RMS have been associated with seq...

    Authors: Charlotte Demoor-Goldschmidt, Sophie Dumoucel, Christine Haie-Meder, Nadège Corradini, Marc-André Mahé and Stéphane Supiot
    Citation: Radiation Oncology 2015 10:108
  26. The optimal fractionation schedule of radiotherapy (RT) for Glioblastoma multiforme (GBM) is yet to be determined. We aim to compare different fractionation regimens and identify prognostic factors to better t...

    Authors: Melissa Azoulay, Fabiano Santos, Luis Souhami, Valerie Panet-Raymond, Kevin Petrecca, Scott Owen, Marie-Christine Guiot, Mariia Patyka, Siham Sabri, George Shenouda and Bassam Abdulkarim
    Citation: Radiation Oncology 2015 10:106
  27. The efficacy of radiotherapy critically depends on the activation of intrinsic cell death programs in cancer cells. This implies that evasion of cell death, a hallmark of human cancers, can contribute to radio...

    Authors: Simone Fulda
    Citation: Radiation Oncology 2015 10:105
  28. To improve the delivery of radiotherapy in gynecologic malignancies and to minimize the irradiation of unaffected tissues by using daily kilovoltage cone beam computed tomography (kV-CBCT) to reduce setup errors.

    Authors: Lihong Yao, Lihong Zhu, Junjie Wang, Lu Liu, Shun Zhou, ShuKun Jiang, Qianqian Cao, Ang Qu and Suqing Tian
    Citation: Radiation Oncology 2015 10:104
  29. Radiation-induced bronchiolitis obliterans organizing pneumonia (BOOP) syndrome is a rarely observed phenomenon characterized by infiltration of the lungs outside of the radiation field, differentiating it fro...

    Authors: Keiko Nemoto Murofushi, Masahiko Oguchi, Masahiko Gosho, Takuyo Kozuka and Hideyuki Sakurai
    Citation: Radiation Oncology 2015 10:103
  30. Small cell carcinoma of the rectum is a rare neoplasm with scant literature to guide treatment. We used the Surveillance Epidemiology and End Results (SEER) database to investigate the role of radiation therap...

    Authors: Aram S Modrek, Howard C Hsu, Cynthia G Leichman and Kevin L Du
    Citation: Radiation Oncology 2015 10:101
  31. Textural features in FDG-PET have been shown to provide prognostic information in a variety of tumor entities. Here we evaluate their predictive value for recurrence and prognosis in NSCLC patients receiving p...

    Authors: Thomas Pyka, Ralph A Bundschuh, Nicolaus Andratschke, Benedikt Mayer, Hanno M Specht, Laszló Papp, Norbert Zsótér and Markus Essler
    Citation: Radiation Oncology 2015 10:100
  32. Radiation-induced rib fracture after stereotactic body radiotherapy (SBRT) for lung cancer has been recently reported. However, incidence of radiation-induced rib fracture after SBRT using moderate fraction si...

    Authors: Masahiko Aoki, Mariko Sato, Katsumi Hirose, Hiroyoshi Akimoto, Hideo Kawaguchi, Yoshiomi Hatayama, Shuichi Ono and Yoshihiro Takai
    Citation: Radiation Oncology 2015 10:99
  33. To determine the long-term impact of stereotactic radiotherapy (SRT) on the quality of life (QoL) of inoperable patients with early-stage non-small cell lung cancer (NSCLC).

    Authors: Rutger J Ubels, Sahar Mokhles, Eleni R Andrinopoulou, Cornelia Braat, Noëlle C van der Voort van Zyp, Shafak Aluwini, Joachim G J V Aerts and Joost J Nuyttens
    Citation: Radiation Oncology 2015 10:98
  34. Machine Performance Check (MPC) is an application to verify geometry and beam performances of TrueBeam Linacs, through automated checks based on their kV-MV imaging systems. In this study, preliminary tests wi...

    Authors: Alessandro Clivio, Eugenio Vanetti, Steven Rose, Giorgia Nicolini, Maria F Belosi, Luca Cozzi, Christof Baltes and Antonella Fogliata
    Citation: Radiation Oncology 2015 10:97
  35. To evaluate the dose-effect relations for myocardial metabolic disorders after mediastinal radiotherapy (RT) by performing iodine-123 β-methyl-iodophenyl pentadecanoic acid (I-123 BMIPP) scintigraphy.

    Authors: Rei Umezawa, Kentaro Takanami, Noriyuki Kadoya, Yujiro Nakajima, Masahide Saito, Hideki Ota, Haruo Matsushita, Toshiyuki Sugawara, Masaki Kubozono, Takaya Yamamoto, Yojiro Ishikawa, Ken Takeda, Yasuyuki Taki, Kei Takase and Keiichi Jingu
    Citation: Radiation Oncology 2015 10:96
  36. This is the final report of a prospective phase I study which evaluated the feasibility, toxicities, and biochemical control in prostate cancer patients treated with a hypofractionated boost utilizing a fiduci...

    Authors: William Chu, D Andrew Loblaw, Kelvin Chan, Gerard Morton, Richard Choo, Ewa Szumacher, Cyril Danjoux, Jean-Philippe Pignol and Patrick Cheung
    Citation: Radiation Oncology 2015 10:95
  37. We aimed to study the radiation induced brachial plexopathy in patients with head and neck squamous cell carcinoma (HNSCC) treated with Sequential Intensity Modulated Radiation Therapy (S-IMRT).

    Authors: Tarita O Thomas, Tamer Refaat, Mehee Choi, Ian Bacchus, Sean Sachdev, Alfred W Rademaker, Vythialingam Sathiaseelan, Achilles Karagianis and Bharat B Mittal
    Citation: Radiation Oncology 2015 10:94
  38. A significant number of patients treated for head and neck squamous cell cancer (HNSCC) undergo enteral tube feeding. Data suggest that avoiding enteral feeding can prevent long-term tube dependence and disuse...

    Authors: Sean Sachdev, Tamer Refaat, Ian D Bacchus, Vythialinga Sathiaseelan and Bharat B Mittal
    Citation: Radiation Oncology 2015 10:93
  39. Intensity-modulated radiotherapy (IMRT) and helical tomotherapy (HT) have been adopted for radiotherapy treatment of anal canal carcinoma (ACC) due to better conformality, dose homogeneity and normal-tissue sp...

    Authors: Rosanna Yeung, Yarrow McConnell, Heather Warkentin, Darren Graham, Brad Warkentin, Kurian Joseph and Corinne M Doll
    Citation: Radiation Oncology 2015 10:92
  40. To compare highly sophisticated intensity-modulated radiotherapy (IMRT) delivered by either helical tomotherapy (HT), RapidArc (RA), IMRT with protons (IMPT) in patients with locally advanced cervical cancer.

    Authors: Simone Marnitz, Waldemar Wlodarczyk, Oliver Neumann, Christhardt Koehler, Mirko Weihrauch, Volker Budach and Luca Cozzi
    Citation: Radiation Oncology 2015 10:91
  41. It is currently not possible to get an approval of our ethics committee for a randomized trial cmparing 5x4 Gy and 10x3 Gy for MSCC that includes patients with favorable survival prognoses. Therefore, this mat...

    Authors: Dirk Rades, Stefan Huttenlocher, Theo Veninga, Amira Bajrovic, Michael Bremer, Volker Rudat and Steven E Schild
    Citation: Radiation Oncology 2015 10:90
  42. To retrospectively analyze the prognostic value of magnetic resonance imaging (MRI)-derived residual tumors after intensity-modulated radiation therapy (IMRT) in the patients with locally-advanced nasopharynge...

    Authors: Yuxiang He, Qin Zhou, Lin Shen, Yajie Zhao, Mingjun Lei, Rui Wei, Liangfang Shen and Shousong Cao
    Citation: Radiation Oncology 2015 10:89
  43. Olfactory neuroblastoma (ONB) is a rare tumor originating from olfactory epithelium. Here we retrospectively analyzed the long-term treatment outcomes and toxicity of radiotherapy for ONB patients for whom com...

    Authors: Takashi Mori, Rikiya Onimaru, Shunsuke Onodera, Kazuhiko Tsuchiya, Koichi Yasuda, Hiromitsu Hatakeyama, Hiroyuki Kobayashi, Shunsuke Terasaka, Akihiro Homma and Hiroki Shirato
    Citation: Radiation Oncology 2015 10:88
  44. To demonstrate that novice dosimetry planners efficiently create clinically acceptable IMRT plans for head and neck cancer (HNC) patients using a commercially available multicriteria optimization (MCO) system.

    Authors: Roel GJ Kierkels, Ruurd Visser, Hendrik P Bijl, Johannes A Langendijk, Aart A van ‘t Veld, Roel JHM Steenbakkers and Erik W Korevaar
    Citation: Radiation Oncology 2015 10:87
  45. Total marrow (lymph-nodes) irradiation (TMI-TMLI) by volumetric modulated arc therapy (VMAT) was shown to be feasible by dosimetric feasibility studies. It was demonstrated that several partially overlapping a...

    Authors: Pietro Mancosu, Pierina Navarria, Giacomo Reggiori, Luca Cozzi, Antonella Fogliata, Anna Gaudino, Francesca Lobefalo, Lucia Paganini, Valentina Palumbo, Barbara Sarina, Antonella Stravato, Luca Castagna, Stefano Tomatis and Marta Scorsetti
    Citation: Radiation Oncology 2015 10:86
  46. The purpose of this study was to investigate the potential dose reduction to the heart, left anterior descending (LAD) coronary artery and the ipsilateral lung for patients treated with tangential and locoregi...

    Authors: Anneli Edvardsson, Martin P Nilsson, Sousana Amptoulach and Sofie Ceberg
    Citation: Radiation Oncology 2015 10:84

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