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  1. The study summarised in this report aimed to investigate the interplay between fluence complexity, dose calculation algorithms, dose calculation spatial resolution and delivery characteristics (monitor units, ...

    Authors: Nicolini Giorgia, Fogliata Antonella, Vanetti Eugenio, Clivio Alessandro, Ammazzalorso Filippo and Cozzi Luca
    Citation: Radiation Oncology 2007 2:42
  2. To investigate whether Radiation therapy (RT) should follow breast conserving surgery in women with ductal carcinoma in situ from breast cancer (DCIS) with objective of decreased mortality, invasive or non inv...

    Authors: Gustavo A Viani, Eduardo J Stefano, Sérgio L Afonso, Lígia I De Fendi, Francisco V Soares, Paola G Leon and Flavio S Guimarães
    Citation: Radiation Oncology 2007 2:28
  3. At Gesellschaft für Schwerionenforschung (GSI) more than 330 patients have been treated with scanned carbon ion beams in a pilot project. To date, only stationary tumors have been treated. In the presence of m...

    Authors: Christoph Bert and Eike Rietzel
    Citation: Radiation Oncology 2007 2:24
  4. Impact of non-pharmacological innovations on cancer cure rates is difficult to assess. It remains unclear, whether outcome improves with 2- [18-F]-fluoro-2-deoxyglucose-positron emission tomography and integra...

    Authors: Sacha Rothschild, Gabriela Studer, Burkhardt Seifert, Pia Huguenin, Christoph Glanzmann, J Bernard Davis, Urs M Lütolf, Thomas F Hany and I Frank Ciernik
    Citation: Radiation Oncology 2007 2:22
  5. Hodgkin's lymphoma (HL) survivors who undergo radiotherapy experience increased risks of second cancers (SC) and cardiac sequelae. To reduce such risks, extended-field radiotherapy (RT) for HL has largely been...

    Authors: Eng-Siew Koh, Tu Huan Tran, Mostafa Heydarian, Rainer K Sachs, Richard W Tsang, David J Brenner, Melania Pintilie, Tony Xu, June Chung, Narinder Paul and David C Hodgson
    Citation: Radiation Oncology 2007 2:13
  6. The sensitizing effects of 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide (DCQ) and ionizing radiation (IR) were determined in four colon cancer cells and in FHs74Int normal intestinal cells.

    Authors: Wafica Itani, Fady Geara, Joelle Haykal, Makhluf Haddadin and Hala Gali-Muhtasib
    Citation: Radiation Oncology 2007 2:1
  7. Medulloblastoma and other types of tumors that gain access to the cerebrospinal fluid can spread throughout the craniospinal axis. The purpose of this study was to devise a simple multi-compartment kinetic mod...

    Authors: Jeffrey J Meyer, Lawrence B Marks, Edward C Halperin and John P Kirkpatrick
    Citation: Radiation Oncology 2006 1:48
  8. Tumors of the skull base pose unique challenges to radiosurgical treatment because of their irregular shapes, proximity to critical structures and variable tumor volumes. In this study, we investigate whether ...

    Authors: Sean P Collins, Nicholas D Coppa, Ying Zhang, Brian T Collins, Donald A McRae and Walter C Jean
    Citation: Radiation Oncology 2006 1:46
  9. The aim of this study was to compare and to validate different dose calculation algorithms for the use in radiation therapy of small lung lesions and to optimize the treatment planning using accurate dose calc...

    Authors: Barbara Dobler, Cornelia Walter, Antje Knopf, Daniella Fabri, Rainer Loeschel, Martin Polednik, Frank Schneider, Frederik Wenz and Frank Lohr
    Citation: Radiation Oncology 2006 1:45
  10. Pelvic Radiotherapy (RT) as a postoperative treatment for endometrial cancer improves local regional control. Brachytherapy also improves vaginal control. Both treatments imply significant side effects that a ...

    Authors: Marcus S Castilho, Alexandre A Jacinto, Gustavo A Viani, Andre Campana, Juliana Carvalho, Robson Ferrigno, Paulo ERS Novaes, Ricardo C Fogaroli and Joao V Salvajoli
    Citation: Radiation Oncology 2006 1:44
  11. 4-dimensional CT (4DCT) scans are increasingly used to account for mobility during radiotherapy planning. As variations in respiratory patterns can alter observed motion, with consequent changes in the generat...

    Authors: Ylanga G van der Geld, Frank J Lagerwaard, John R van Sörnsen de Koste, Johan P Cuijpers, Ben J Slotman and Suresh Senan
    Citation: Radiation Oncology 2006 1:43
  12. Hypofractionated radiotherapy may overcome repopulation in rapidly proliferating tumors such as lung cancer. It is more convenient for the patients and reduces health care costs. This study reports our results...

    Authors: Sergio L Faria, Luis Souhami, Lorraine Portelance, Marie Duclos, Te Vuong, David Small and Carolyn R Freeman
    Citation: Radiation Oncology 2006 1:42
  13. We retrospectively evaluated acute toxicity in 88 patients that were treated with capecitabine and concurrent radiotherapy to the upper abdomen. These patients included 28 (32%) with pancreatic adenocarcinoma,...

    Authors: Prajnan Das, Robert A Wolff, James L Abbruzzese, Gauri R Varadhachary, Douglas B Evans, Jean Nicolas Vauthey, Andrew Baschnagel, Marc E Delclos, Sunil Krishnan, Nora A Janjan and Christopher H Crane
    Citation: Radiation Oncology 2006 1:41
  14. Aim of this work was to assess loco-regional disease control in head and neck cancer (HNC) patients treated with postoperative intensity modulated radiation therapy (pIMRT). For comparative purposes, risk feat...

    Authors: Gabriela Studer, Katrin Furrer, Bernard J Davis, Sandro S Stoeckli, Roger A Zwahlen, Urs M Luetolf and Christoph Glanzmann
    Citation: Radiation Oncology 2006 1:40
  15. New concepts in radiation oncology are based on the concept that combinations of irradiation and molecular targeted drugs can yield synergistic or at least additive effects. Up to now the combination of two tr...

    Authors: Maximilian Niyazi and Claus Belka
    Citation: Radiation Oncology 2006 1:39
  16. To report the treatment results and prognostic factors of childhood patients with Hodgkin's disease treated with chemotherapy (CT) followed by low dose radiotherapy (RT).

    Authors: Gustavo A Viani, Marcus S Castilho, Paulo E Novaes, Celia G Antonelli, Robson Ferrigno, Cassio A Pellizzon, Ricardo C Fogaroli, Maria A Conte and Joao V Salvajoli
    Citation: Radiation Oncology 2006 1:38
  17. A protocol of electronic portal imaging (EPI) registration for the verification of radiation treatment fields has been implemented at our institution. A template is generated using the reference images, which ...

    Authors: Eric Berthelet, Pauline T Truong, Sergei Zavgorodni, Veronika Moravan, Mitchell C Liu, Jim Runkel, Bill Bendorffe and Dorothy Sayers
    Citation: Radiation Oncology 2006 1:37
  18. Treatment of choroidal melanoma with radiation often involves placement of customized brachytherapy eye-plaques. However, the dosimetric properties inherent in source-based radiotherapy preclude facile dose op...

    Authors: Carlos Esquivel Jr., Clifton D Fuller, Robert G Waggener, Adrian Wong, Martin Meltz, Melissa Blough, Tony Y Eng and Charles R Thomas Jr.
    Citation: Radiation Oncology 2006 1:36
  19. Mantle Cell Lymphoma (MCL) is a well-known histological and clinical subtype of B-cell non-Hodgkin's Lymphomas. It is usually characterized by an aggressive disease course, presenting with advanced stage disea...

    Authors: Andrea Riccardo Filippi, Pierfrancesco Franco, Marco Galliano and Umberto Ricardi
    Citation: Radiation Oncology 2006 1:35
  20. The dose distribution to the rectum, delineated as solid organ, rectal wall and rectal surface, in 3D conformal (3D-CRT) and intensity-modulated radiotherapy treatment (IMRT) planning for localized prostate ca...

    Authors: Matthias Guckenberger, Jürgen Meyer, Kurt Baier, Dirk Vordermark and Michael Flentje
    Citation: Radiation Oncology 2006 1:34
  21. As a foundation for a dose escalation trial, we sought to characterize duodenal and non-duodenal small bowel organ motion between fractions of pancreatic radiation therapy.

    Authors: Anurag K Singh, Ryan M Tierney, Daniel A Low, Parag J Parikh, Robert J Myerson, Joseph O Deasy, Catherine S Wu, Gisele C Pereira, Sasha H Wahab, Sasa MS Mutics, Perry W Grigsby and Andrew J Hope
    Citation: Radiation Oncology 2006 1:33
  22. Modern radiotherapy (RT) reduces the side effects at organ at risk. However, skin toxicity is still a major problem in many entities, especially head and neck cancer. Some substances like chemotherapy provide ...

    Authors: Kurt Putnik, Peter Stadler, Christof Schäfer and Oliver Koelbl
    Citation: Radiation Oncology 2006 1:32
  23. Intensity modulated radiotherapy (IMRT) is a powerful tool, which might go a long way in reducing radiation doses to critical structures and thereby reduce long term morbidities.

    Authors: Tejinder Kataria, Sheh Rawat, SN Sinha, C Garg, NK Bhalla and PS Negi
    Citation: Radiation Oncology 2006 1:31
  24. We prospectively reviewed response rates, local control, and side effects after non-fractionated stereotactic high single-dose body radiation therapy for lung tumors.

    Authors: Peter Fritz, Hans-Jörg Kraus, Werner Mühlnickel, Udo Hammer, Wolfram Dölken, Walburga Engel-Riedel, Assad Chemaissani and Erich Stoelben
    Citation: Radiation Oncology 2006 1:30
  25. To investigate the outcome of HIV-seropositive patients under highly active antiretroviral treatment (HAART) with anal cancer treated with radiotherapy (RT) alone or in combination with standard chemotherapy (...

    Authors: Christoph Oehler-Jänne, Burkhardt Seifert, Urs M Lütolf and I Frank Ciernik
    Citation: Radiation Oncology 2006 1:29
  26. To report early observation of transient PSA elevations on this pilot study of external beam radiation therapy and magnetic resonance imaging (MRI) guided high dose rate (HDR) brachytherapy boost.

    Authors: Anurag K Singh, Peter Guion, Robert C Susil, Deborah E Citrin, Holly Ning, Robert W Miller, Karen Ullman, Sharon Smith, Nancy Sears Crouse, Denise J Godette, Bronwyn R Stall, CNorman Coleman, Kevin Camphausen and Cynthia Ménard
    Citation: Radiation Oncology 2006 1:28
  27. Salvage therapy in head and neck cancer (HNC) is a controversy issue and the literature is scarce regarding the use of interstitial high-dose rate brachytherapy (I-HDR) in HNC. We evaluated the long-term resul...

    Authors: Antonio CassioAssis Pellizzon, João Victor Salvajoli, Luiz Paulo Kowalski and Andre Lopes Carvalho
    Citation: Radiation Oncology 2006 1:27
  28. Helical Tomotherapy (HT) integrates linear accelerator and computerized tomography (CT) technology to deliver IMRT. Targets are localized (i.e. outlined as gross tumor volume [GTV] and planning target volume [...

    Authors: José A Peñagarícano, Yulong Yan, Chengyu Shi, Mark E Linskey and Vaneerat Ratanatharathorn
    Citation: Radiation Oncology 2006 1:26
  29. The tumor response to preoperative radiotherapy of locally advanced rectal cancer varies greatly, warranting the use of experimental models to assay the efficacy of molecular targeting agents in rectal cancer ...

    Authors: Kjersti Flatmark, Ragnhild V Nome, Sigurd Folkvord, Åse Bratland, Heidi Rasmussen, Mali Strand Ellefsen, Øystein Fodstad and Anne Hansen Ree
    Citation: Radiation Oncology 2006 1:25
  30. To report the relapse and survival rates associated to treatment for patients with stage IC, grade 2 or grade 3 and IB grade 3 diseases considered high risk patients group for relapse.

    Authors: Gustavo A Viani, Barbara F Patia, Antonio C Pellizzon, Marcel D De Melo, Paulo E Novaes, Ricardo C Fogaroli, Maria A Conte and Joao V Salvajoli
    Citation: Radiation Oncology 2006 1:24
  31. The aim of the study was to evaluate the clinical outcome of intensity modulated radiotherapy (IMRT) in 46 patients with paranasal sinus tumors with special respect to treatment-related toxicity.

    Authors: Stephanie E Combs, Stephan Konkel, Daniela Schulz-Ertner, Marc W Münter, Jürgen Debus, Peter E Huber and Christoph Thilmann
    Citation: Radiation Oncology 2006 1:23
  32. There is no consensus as to the prognostic model for brachytherapy of tongue carcinoma. This study was designed to evaluate the prognostic factors for local control based on a large population under a unified ...

    Authors: Sayako Oota, Hitoshi Shibuya, Ryo-ichi Yoshimura, Hiroshi Watanabe and Masahiko Miura
    Citation: Radiation Oncology 2006 1:21
  33. To evaluate the prognostic factors associated with overall survival in patients with brain metastasis treated with whole brain radiotherapy (WBRT) and estimate the potential improvement in survival for patient...

    Authors: Elisa Y Saito, Gustavo A Viani, Robson Ferrigno, Ricardo A Nakamura, Paulo E Novaes, Cassio A Pellizzon, Ricardo C Fogaroli, Maria A Conte and Joao V Salvajoli
    Citation: Radiation Oncology 2006 1:20
  34. Patients with brain metastases represent a heterogeneous group where selection of the most appropriate treatment depends on many patient- and disease-related factors. Eventually, a considerable proportion of p...

    Authors: Carsten Nieder, Anca L Grosu, Sabrina Astner, Reinhard Thamm and Michael Molls
    Citation: Radiation Oncology 2006 1:19
  35. To investigate the potential of parotic gland sparing of intensity modulated radiotherapy (3D-c-IMRT) performed with metallic compensators for head and neck cancer in a clinical series by analysis of dose dist...

    Authors: Thomas G Wendt, Nasrin Abbasi-Senger, Henning Salz, Ines Pinquart, Sven Koscielny, Susi-Marie Przetak and Tilo Wiezorek
    Citation: Radiation Oncology 2006 1:18
  36. Presenting the initial clinical results in the treatment of complex shaped adenoid cystic carcinomas (ACC) of the head and neck region by inverse planned stereotactic IMRT.

    Authors: MW Münter, D Schulz-Ertner, H Hof, A Nikoghosyan, A Jensen, S Nill, P Huber and J Debus
    Citation: Radiation Oncology 2006 1:17
  37. The purpose of the study was the clinical implementation of a kV cone beam CT (CBCT) for setup correction in radiotherapy.

    Authors: Christoph Thilmann, Simeon Nill, Thomas Tücking, Angelika Höss, Bernd Hesse, Lars Dietrich, Rolf Bendl, Bernhard Rhein, Peter Häring, Christian Thieke, Uwe Oelfke, Juergen Debus and Peter Huber
    Citation: Radiation Oncology 2006 1:16
  38. Cervical cancer continues to be a significant health burden worldwide. Globally, the majority of cancers are locally advanced at diagnosis; hence, radiation remains the most frequently used therapeutical modal...

    Authors: Myrna Candelaria, Alicia Garcia-Arias, Lucely Cetina and Alfonso Dueñas-Gonzalez
    Citation: Radiation Oncology 2006 1:15
  39. The risk of severe cardiovascular toxicity, specifically thromboembolic events (TE), in patients with cervical cancer receiving concurrent irradiation and cisplatin chemotherapy is reported to be less than 1% ...

    Authors: Jon C Anders, Perry W Grigsby and Anurag K Singh
    Citation: Radiation Oncology 2006 1:14
  40. To evaluate intensity-modulated radiation therapy (IMRT) as an alternative to conformal radiotherapy (CRT) or 4-field box boost (4FB) in women with gynecologic malignancies who are unsuitable for brachytherapy...

    Authors: Philip Chan, Inhwan Yeo, Gregory Perkins, Anthony Fyles and Michael Milosevic
    Citation: Radiation Oncology 2006 1:13
  41. The presentation reviews the modus operandi of the dose modifying drug Pentoxifylline and the dose enhancement factors which can be achieved in different cell types. Preclinical and clinical data show that Pen...

    Authors: Lothar Bohm
    Citation: Radiation Oncology 2006 1:12
  42. Epidermal growth factor receptor (EGFR) is a member of the ErbB family of receptors. Its stimulation by endogenous ligands, EGF or transforming growth factor-alpha (TGF-α) results in activation of intracellula...

    Authors: Michel Zimmermann, Abderrahim Zouhair, David Azria and Mahmut Ozsahin
    Citation: Radiation Oncology 2006 1:11
  43. The long-term dose-effect relationship for specific cardiac structures in mediastinal radiotherapy has rarely been investigated. As part of an interdisciplinary project, the 3-D dose distribution within the he...

    Authors: Dirk Vordermark, Ines Seufert, Franz Schwab, Oliver Kölbl, Margret Kung, Christiane Angermann and Michael Flentje
    Citation: Radiation Oncology 2006 1:10
  44. Current approaches for the improvement of bNED for prostate cancer patients treated with radiotherapy mainly focus on dose escalation. However molecularly targeted approaches may also turn out to be of value. ...

    Authors: U Ganswindt, W Budach, V Jendrossek, G Becker, M Bamberg and C Belka
    Citation: Radiation Oncology 2006 1:9
  45. Respiration-gated radiotherapy can permit the irradiation of smaller target volumes. 4DCT scans performed for routine treatment were retrospectively analyzed to establish the benefits of gating in stage III no...

    Authors: René WM Underberg, John R van Sörnsen de Koste, Frank J Lagerwaard, Andrew Vincent, Ben J Slotman and Suresh Senan
    Citation: Radiation Oncology 2006 1:8
  46. Alkylphosphocholines constitute a novel class of antineoplastic synthetic phospholipid derivatives that induce apoptosis of human tumor cell lines by targeting cellular membranes. We could recently show that t...

    Authors: Amelie Rübel, René Handrick, Lars H Lindner, Matthias Steiger, Hansjörg Eibl, Wilfried Budach, Claus Belka and Verena Jendrossek
    Citation: Radiation Oncology 2006 1:6
  47. To report the retrospective analysis of patients with locally advanced rectal cancer treated with neodjuvant radiochemotherapy.

    Authors: Robson Ferrigno, Paulo Eduardo Ribeiro dos Santos Novaes, Maria Letícia Gobo Silva, Ines Nobuko Nishimoto, Wilson Toshihiko Nakagawa, Benedito Mauro Rossi, Fábio de Oliveira Ferreira and Ademar Lopes
    Citation: Radiation Oncology 2006 1:5

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