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  1. Radiation-induced DNA double-strand break (DSB) repair can be tested by using pulsed-field gel electrophoresis (PFGE) in agarose-encapsulated cells. However, previous studies have reported that this assay is i...

    Authors: Josep Balart, Gemma Pueyo, Lara I de Llobet, Marta Baro, Xavi Sole, Susanna Marin, Oriol Casanovas, Ricard Mesia and Gabriel Capella
    Citation: Radiation Oncology 2011 6:6
  2. Breast cancers are more frequently diagnosed at an early stage and currently have improved long term outcomes. Late normal tissue complications induced by adjuvant radiotherapy like secondary cancers or cardio...

    Authors: Jean-Philippe Pignol, Brian M Keller and Ananth Ravi
    Citation: Radiation Oncology 2011 6:5
  3. High-precision radiation therapy techniques such as IMRT or sterotactic radiosurgery, delivers more complex treatment fields than conventional techniques. The increased complexity causes longer dose delivery t...

    Authors: Xin Wang, Xiao-Peng Xiong, Jiade Lu, Guo-Pei Zhu, Shao-Qin He, Chao-Su Hu and Hong-Mei Ying
    Citation: Radiation Oncology 2011 6:4
  4. Surgical resection followed by radiotherapy and temozolomide in newly diagnosed glioblastoma can prolong survival, but it is not curative. For patients with disease progression after frontline therapy, there i...

    Authors: Kathryn Beal, Lauren E Abrey and Philip H Gutin
    Citation: Radiation Oncology 2011 6:2
  5. To evaluate the objective and subjective long term swallowing function, and to relate dysphagia to the radiation dose delivered to the critical anatomical structures in head and neck cancer patients treated wi...

    Authors: Evangelia Peponi, Christoph Glanzmann, Bettina Willi, Gerhard Huber and Gabriela Studer
    Citation: Radiation Oncology 2011 6:1
  6. To evaluate the effectivity of fractionated radiotherapy in adolescent and adult patients with pineal parenchymal tumors (PPT).

    Authors: Eva Maria Stoiber, Benjamin Schaible, Klaus Herfarth, Daniela Schulz-Ertner, Peter E Huber, Jürgen Debus and Susanne Oertel
    Citation: Radiation Oncology 2010 5:122
  7. Chemo-radiotherapy offers an alternative to primary surgery and adjuvant therapy for the management of locally advanced stage IV squamous cell carcinomas of the tonsil.

    Authors: Robin J D Prestwich, Kiran Kancherla, Didem Colpan Oksuz, Deborah Williamson, Karen E Dyker, Catherine Coyle and Mehmet Sen
    Citation: Radiation Oncology 2010 5:121
  8. This paper compares the calculated dose to target and normal tissues when using pencil beam (PBC), superposition/convolution (AAA) and Monte Carlo (MC) algorithms for whole breast (WBI) and accelerated partial...

    Authors: Parminder S Basran, Sergei Zavgorodni, Tanya Berrang, Ivo A Olivotto and Wayne Beckham
    Citation: Radiation Oncology 2010 5:120
  9. We aim to investigate the possibility of using 18F-positron emission tomography/computer tomography (PET-CT) to predict the histopathologic response in locally advanced rectal cancer (LARC) treated with preope...

    Authors: Pablo Palma, Raquel Conde-Muíño, Antonio Rodríguez-Fernández, Inmaculada Segura-Jiménez, Rocío Sánchez-Sánchez, Javier Martín-Cano, Manuel Gómez-Río, José A Ferrón and José M Llamas-Elvira
    Citation: Radiation Oncology 2010 5:119
  10. Adjuvant therapy for T3N0 rectal cancer was controversial with respect to both radiation and the use of a combined regimen of chemotherapy. We evaluated both clinical features and biomarkers and sought to dete...

    Authors: Ji Zhu, Ye Xu, Weilie Gu, Junjie Peng, Gang Cai, Guoxiang Cai, Wenjie Sun, Weiqi Shen, Sanjun Cai and Zhen Zhang
    Citation: Radiation Oncology 2010 5:118
  11. This retrospective analysis reports on the comparative outcome of acute gastrointestinal (GI) and genitourinary (GU) toxicities between conformal radiation therapy (CRT) and intensity modulated radiation thera...

    Authors: Robson Ferrigno, Adriana Santos, Lidiane C Martins, Eduardo Weltman, Michael J Chen, Roberto Sakuraba, Cleverson P Lopes and José C Cruz
    Citation: Radiation Oncology 2010 5:117
  12. To examine the role of brachytherapy for aged patients 80 or more in the trend of rapidly increasing number.

    Authors: Hideya Yamazaki, Ken Yoshida, Tadayuki Kotsuma, Yasuo Yoshioka, Masahiko Koizumi, Souhei Furukawa, Naoya Kakimoto, Kimishige Shimizutani and Tsunehiko Nishimura
    Citation: Radiation Oncology 2010 5:116
  13. Intensity-modulated radiotherapy (IMRT) may allow improvement in plan quality for treatment of liver cancer, however increasing radiation modulation complexity can lead to increased uncertainties and requireme...

    Authors: Mark T Lee, Thomas G Purdie, Cynthia L Eccles, Michael B Sharpe and Laura A Dawson
    Citation: Radiation Oncology 2010 5:115
  14. Intracranial malignant peripheral nerve sheath tumors are rare entities that carry a poor prognosis. To date, there are no established therapeutic strategies for these tumors.

    Authors: Konstantinos Gousias, Jan Boström, Attila Kovacs, Pitt Niehusmann, Ingo Wagner and Rudolf Kristof
    Citation: Radiation Oncology 2010 5:114
  15. A variety of hypofractionated radiotherapy schedules has been proposed after breast conserving surgery in the attempt to shorten the overall treatment time. The aim of the present study is to assess acute and ...

    Authors: Letizia Deantonio, Giuseppina Gambaro, Debora Beldì, Laura Masini, Sara Tunesi, Corrado Magnani and Marco Krengli
    Citation: Radiation Oncology 2010 5:112
  16. Radiation therapy after lumpectomy is a standard part of breast conserving therapy for invasive breast carcinoma. The most frequently used schedule worldwide is 60 Gy in 30 fractions in 6 weeks, a time commitm...

    Authors: Marina Guenzi, Stefano Vagge, Ngwa Che Azinwi, Alessia D'Alonzo, Liliana Belgioia, Stefania Garelli, Marco Gusinu and Renzo Corvò
    Citation: Radiation Oncology 2010 5:111
  17. Several comparison studies have shown the capability of VMAT to achieve similar or better plan quality as IMRT, while reducing the treatment time. The experience of VMAT in a multi vendor environment is limite...

    Authors: Judith Alvarez-Moret, Fabian Pohl, Oliver Koelbl and Barbara Dobler
    Citation: Radiation Oncology 2010 5:110
  18. The phosphatidylinositol-3-kinase (PI3K)/Akt pathway is frequently deregulated in prostate cancer and associated with neoplastic transformation, malignant progression, and enhanced resistance to classical chem...

    Authors: Justine Rudner, Carola-Ellen Ruiner, René Handrick, Hans-Jörg Eibl, Claus Belka and Verena Jendrossek
    Citation: Radiation Oncology 2010 5:108
  19. We have shown that the radio sensitizer DCQ enhances sensitivity of HCT116 human colon cancer cells to hypoxia. However, it is not known whether the p53 or p21 genes influence cellular response to DCQ. In this...

    Authors: Mona El-Khatib, Fady Geara, Makhluf J Haddadin and Hala Gali-Muhtasib
    Citation: Radiation Oncology 2010 5:107
  20. A study was performed to assess dosimetric characteristics of volumetric modulated arcs (RapidArc, RA) and fixed field intensity modulated therapy (IMRT) for Whole Abdomen Radiotherapy (WAR) after ovarian cancer.

    Authors: Umesh Mahantshetty, Swamidas Jamema, Reena Engineer, Deepak Deshpande, Rajiv Sarin, Antonella Fogliata, Giorgia Nicolini, Alessandro Clivio, Eugenio Vanetti, Shyamkishore Shrivastava and Luca Cozzi
    Citation: Radiation Oncology 2010 5:106
  21. There are no specific recommendations for the management of breast cancer patients with germ-line p53 mutations, an exceptional genetic condition, particularly regarding postoperative radiotherapy. Preclinical...

    Authors: Steve Heymann, Suzette Delaloge, Arslane Rahal, Olivier Caron, Thierry Frebourg, Lise Barreau, Corinne Pachet, Marie-Christine Mathieu, Hugo Marsiglia and Céline Bourgier
    Citation: Radiation Oncology 2010 5:104
  22. Breast conserving therapy (BCT) is an accepted treatment for early-stage breast cancer. This study aimed to measure prospectively acute radiation-related toxicity and to create a comprehensive data base for lo...

    Authors: Razvan M Galalae, Jürgen Schultze, Kirsten Eilf and Bernhard Kimmig
    Citation: Radiation Oncology 2010 5:103
  23. Local control in adjuvant/definitive RT of adenoid cystic carcinoma (ACC) is largely dose-dependent. However, some clinical situations do not allow application of tumouricidal doses (i.e. re-irradiation) hence...

    Authors: Alexandra D Jensen, Jürgen Krauss, Wilko Weichert, Jürgen Debus and Marc W Münter
    Citation: Radiation Oncology 2010 5:102
  24. To investigate whether expression of carbonic anhydrase XII (CA12) is associated with histologic grade of the tumors and radiotherapy outcomes of the patients with invasive cervical cancer.

    Authors: Chong Woo Yoo, Byung-Ho Nam, Joo-Young Kim, Hye-Jin Shin, Hyunsun Lim, Sun Lee, Su-Kyoung Lee, Myong-Cheol Lim and Yong-Jung Song
    Citation: Radiation Oncology 2010 5:101
  25. Adjuvant local-regional radiotherapy (LRRT) is routinely recommended for breast cancer patients. It is well known being related to pulmonary side-effects. We studied post-RT radiological changes on X-ray and C...

    Authors: Ulla Blom Goldman, Berit Wennberg, Gunilla Svane, Håkan Bylund and Pehr Lind
    Citation: Radiation Oncology 2010 5:99
  26. The National Comprehensive Cancer Network (NCCN) guidelines recommend radiotherapy as a standard treatment for patients with a high risk of recurrence in gastric cancer. Because gastric cancer demonstrates lim...

    Authors: Xinhua Liao, Xiangming Che, Wei Zhao, Danjie Zhang, Houlong Long, Prakash Chaudhary and Haijun LI
    Citation: Radiation Oncology 2010 5:98
  27. To investigate whether whole-liver radiotherapy (RT) is beneficial in end-stage colorectal cancer with massive liver metastases and severe hepatic dysfunction.

    Authors: Seung-Gu Yeo, Dae Yong Kim, Tae Hyun Kim, Sun Young Kim, Yong Sang Hong and Kyung Hae Jung
    Citation: Radiation Oncology 2010 5:97
  28. The cone beam CT (CBCT) guided radiation can reduce the systematic and random setup errors as compared to the skin-mark setup. However, the residual and intrafractional (RAIF) errors are still unknown. The pur...

    Authors: Gang Cai, Wei-Gang Hu, Jia-Yi Chen, Xiao-Li Yu, Zi-Qiang Pan, Zhao-Zhi Yang, Xiao-Mao Guo, Zhi-Min Shao and Guo-Liang Jiang
    Citation: Radiation Oncology 2010 5:96
  29. To report acute toxicity, initial outcome results and planning therapeutic parameters in radiation treatment of advanced lung cancer (stage III) with volumetric modulated arcs using RapidArc (RA).

    Authors: Marta Scorsetti, Pierina Navarria, Pietro Mancosu, Filippo Alongi, Simona Castiglioni, Raffaele Cavina, Luca Cozzi, Antonella Fogliata, Sara Pentimalli, Angelo Tozzi and Armando Santoro
    Citation: Radiation Oncology 2010 5:94
  30. To report about early clinical experience in radiation treatment of head and neck cancer of different sites and histology by volumetric modulated arcs with the RapidArc technology.

    Authors: Marta Scorsetti, Antonella Fogliata, Simona Castiglioni, Caterina Bressi, Mario Bignardi, Piera Navarria, Pietro Mancosu, Luca Cozzi, Sara Pentimalli, Filippo Alongi and Armando Santoro
    Citation: Radiation Oncology 2010 5:93
  31. To compare volumetric-modulated arc therapy (RapidArc) plans with conventional intensity-modulated radiation therapy (IMRT) plans in anal canal cancers.

    Authors: Sabine Vieillot, David Azria, Claire Lemanski, Carmen Llacer Moscardo, Sophie Gourgou, Jean-Bernard Dubois, Norbert Aillères and Pascal Fenoglietto
    Citation: Radiation Oncology 2010 5:92
  32. The aim of this study was to evaluate treatment results in our hypopharyngeal cancer patients.

    Authors: Morgan Fu-Ti Chang, Hung-Ming Wang, Chung-Jan Kang, Shiang-Fu Huang, Chien-Yu Lin, Kang-Hsing Fang, Eric Yen-Chao Chen, I-How Chen, Chun-Ta Liao and Joseph Tung-Chieh Chang
    Citation: Radiation Oncology 2010 5:91
  33. Basal cell adenocarcinoma accounts for approximately 1.6% of all salivary gland neoplasms. In this report, we describe our experiences of treatment for BCAC with carbon ion radiotherapy in our institution.

    Authors: Keiichi Jingu, Azusa Hasegawa, Jun-Etsu Mizo, Hiroki Bessho, Takamichi Morikawa, Hiroshi Tsuji, Hirohiko Tsujii and Tadashi Kamada
    Citation: Radiation Oncology 2010 5:89
  34. This study evaluated the effectiveness and safety of preoperative chemoradiotherapy with capecitabine in patients with locally advanced resectable rectal cancer. This report summarizes the results of the phase...

    Authors: Vaneja Velenik, Irena Oblak and Franc Anderluh
    Citation: Radiation Oncology 2010 5:88
  35. The aim was to identify preimplant factors affecting postimplant prostate volume and the increase in prostate volume after transperineal interstitial prostate brachytherapy with 125I free seeds.

    Authors: Akitomo Sugawara, Jun Nakashima, Etsuo Kunieda, Hirohiko Nagata, Hirotaka Asakura, Mototsugu Oya and Naoyuki Shigematsu
    Citation: Radiation Oncology 2010 5:86
  36. DNA-damage assays, quantifying the initial number of DNA double-strand breaks induced by radiation, have been proposed as a predictive test for radiation-induced toxicity. Determination of radiation-induced ap...

    Authors: Beatriz Pinar, Luis Alberto Henríquez-Hernández, Pedro C Lara, Elisa Bordon, Carlos Rodriguez-Gallego, Marta Lloret, Maria Isabel Nuñez and Mariano Ruiz De Almodovar
    Citation: Radiation Oncology 2010 5:85
  37. This is a prospective comparison of weekly cisplatin to weekly paclitaxel as concurrent chemotherapy with standard radiotherapy for locally advanced cervical carcinoma.

    Authors: Fady B Geara, Ali Shamseddine, Ali Khalil, Mirna Abboud, Maya Charafeddine and Muhieddine Seoud
    Citation: Radiation Oncology 2010 5:84
  38. Radiotherapy for retroperitoneal sarcomas remains controversial and a technical challenge considering the threshold of contiguous critical organs tolerance. We performed consecutive RapidArc dosimetric plans i...

    Authors: Carmen Llacer-Moscardo, François Quenet, David Azria and Pascal Fenoglietto
    Citation: Radiation Oncology 2010 5:83
  39. Osteopontin (OPN) is a secreted glycophosphoprotein that is overexpressed in various tumors, and high levels of OPN have been associated with poor prognosis of cancer patients. In patients with head and neck c...

    Authors: Antje Hahnel, Henri Wichmann, Matthias Kappler, Matthias Kotzsch, Dirk Vordermark, Helge Taubert and Matthias Bache
    Citation: Radiation Oncology 2010 5:82
  40. The treatment schedules for stereotactic body radiotherapy (SBRT) for lung cancer vary from institution to institution. Several reports have indicated that stage IB patients had worse outcomes than stage IA pa...

    Authors: Fumiya Baba, Yuta Shibamoto, Hiroyuki Ogino, Rumi Murata, Chikao Sugie, Hiromitsu Iwata, Shinya Otsuka, Katsura Kosaki, Aiko Nagai, Taro Murai and Akifumi Miyakawa
    Citation: Radiation Oncology 2010 5:81
  41. The purpose of this study was to determine the expected time to prostate specific antigen (PSA) normalization with or without neoadjuvant androgen deprivation (NAAD) therapy after treatment with intensity modu...

    Authors: Matthew D Schmitz, Gilbert DA Padula, Patrick Y Chun and Alan T Davis
    Citation: Radiation Oncology 2010 5:80
  42. To investigate the significance of monitoring the levels of the serum squamous cell carcinoma antigen (SCC-Ag) for the detection of recurrent disease in patients with cervical cancer treated by concurrent chem...

    Authors: Sang Min Yoon, Kyung Hwan Shin, Joo-Young Kim, Sang Soo Seo, Sang-Yoon Park, Sung Ho Moon and Kwan Ho Cho
    Citation: Radiation Oncology 2010 5:78

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