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  1. The shape of the dose-response curve at low doses differs from the linear quadratic model. The effect of a radio-adaptive response is the centre of many studies and well known inspite that the clinical applica...

    Authors: Silke B Schwarz, Pamela M Schaffer, Ulrike Kulka, Birgit Ertl-Wagner, Roswitha Hell and Moshe Schaffer
    Citation: Radiation Oncology 2008 3:12
  2. Late effects after radiotherapy in childhood and adolescence have mainly been characterized retrospectively with small patient numbers. However, these analyses are limited due to little information regarding o...

    Authors: Tobias Bolling, Andreas Schuck, Hildegard Pape, Christian Rube, Barbara Pollinger, Beate Timmermann, Rolf D Kortmann, Karin Dieckmann and Normann Willich
    Citation: Radiation Oncology 2008 3:10
  3. To report our experience treating soft tissue sarcoma (STS) with high dose rate brachytherapy alone (HBRT) or in combination with external beam radiotherapy (EBRT) in pediatric patients.

    Authors: Gustavo A Viani, Paulo E Novaes, Alexandre A Jacinto, Celia B Antonelli, Antonio Cassio A Pellizzon, Elisa Y Saito and João V Salvajoli
    Citation: Radiation Oncology 2008 3:9
  4. To assess whether an expanded (five level) risk stratification system can be used to identify the sub-group of intermediate risk patients with prostate cancer who benefit from combining androgen deprivation th...

    Authors: Matthew Beasley, Scott G Williams and Tom Pickles
    Citation: Radiation Oncology 2008 3:8
  5. The shift from conventional two-dimensional (2D) to three-dimensional (3D)-conformal target definition and dose-planning seems to have introduced volumetric as well as geometric changes. The purpose of this st...

    Authors: Hans Paul van der Laan, Wil V Dolsma, John H Maduro, Erik W Korevaar and Johannes A Langendijk
    Citation: Radiation Oncology 2008 3:6
  6. The aim of this treatment planning study was to investigate the potential advantages of intensity-modulated (IM) proton therapy (IMPT) compared with IM photon therapy (IMRT) in nasopharyngeal carcinoma (NPC).

    Authors: Zahra Taheri-Kadkhoda, Thomas Björk-Eriksson, Simeon Nill, Jan J Wilkens, Uwe Oelfke, Karl-Axel Johansson, Peter E Huber and Marc W Münter
    Citation: Radiation Oncology 2008 3:4
  7. To evaluate the risk of rectal, bladder and small bowel toxicity in intensity modulated radiation therapy (IMRT) of the prostate only compared to additional irradiation of the pelvic lymphatic region.

    Authors: Matthias Guckenberger, Kurt Baier, Anne Richter, Dirk Vordermark and Michael Flentje
    Citation: Radiation Oncology 2008 3:3
  8. Androgen suppression treatment (AST) might increase the risk of cardiac morbidity in prostate cancer patients. Possible explanations were provided, however, they disregard the potential contribution of prophyl...

    Authors: Carsten Nieder, Adam Pawinski, Nicolaus H Andratschke and Michael Molls
    Citation: Radiation Oncology 2008 3:2
  9. To compare two strategies of dynamic intensity modulated radiation therapy (dIMRT) with 3-dimensional conformal radiation therapy (3DCRT) in the setting of hypofractionated high-risk prostate cancer treatment.

    Authors: Jasper Yuen, George Rodrigues, Kristina Trenka, Terry Coad, Slav Yartsev, David D'Souza, Michael Lock and Glenn Bauman
    Citation: Radiation Oncology 2008 3:1
  10. Radiation dermatitis is a common side effect of radiation therapy (RT). In severe cases, RT must be interrupted until the skin heals, which can compromise treatment. The purpose of the study was to compare an ...

    Authors: Thomas E Merchant, Christina Bosley, Julie Smith, Pam Baratti, David Pritchard, Tina Davis, Chenghong Li and Xiaoping Xiong
    Citation: Radiation Oncology 2007 2:45
  11. Set-up errors are an inherent part of radiation treatment process. Coverage of target volume is a direct function of set-up margins, which should be optimized to prevent inadvertent irradiation of adjacent nor...

    Authors: Tejpal Gupta, Supriya Chopra, Avinash Kadam, Jai Prakash Agarwal, P Reena Devi, Sarbani Ghosh-Laskar and Ketayun Ardeshir Dinshaw
    Citation: Radiation Oncology 2007 2:44
  12. To compare the dosimetric advantage of three different intensity-modulated radiation therapy (IMRT) plans to a three dimensional (3D) conventional radiation treatment for anal cancer with regards to organs-at-...

    Authors: Cathy Menkarios, David Azria, Benoit Laliberté, Carmen Llacer Moscardo, Sophie Gourgou, Claire Lemanski, Jean-Bernard Dubois, Norbert Aillères and Pascal Fenoglietto
    Citation: Radiation Oncology 2007 2:41
  13. The standard treatment of the axilla in breast cancer used to be an axillary lymph node dissection. An axillary lymph node dissection is known to give substantial risks of morbidity. In recent years the sentin...

    Authors: Patty H Spruit, Sabine Siesling, Marloes AG Elferink, Ernest JA Vonk and Carel JM Hoekstra
    Citation: Radiation Oncology 2007 2:40
  14. Recent developments in radiotherapeutic technology have resulted in a new approach to treating patients with localized lung cancer. We report preliminary clinical outcomes using stereotactic radiosurgery with ...

    Authors: Brian T Collins, Kelly Erickson, Cristina A Reichner, Sean P Collins, Gregory J Gagnon, Sonja Dieterich, Don A McRae, Ying Zhang, Shadi Yousefi, Elliot Levy, Thomas Chang, Carlos Jamis-Dow, Filip Banovac and Eric D Anderson
    Citation: Radiation Oncology 2007 2:39
  15. High-dose radiotherapy is standard treatment for patients with brain cancer. However, in preclinical research external beam radiotherapy is limited to heterotopic murine models– high-dose radiotherapy to the m...

    Authors: Joost JC Verhoeff, Lukas JA Stalpers, Annet W Coumou, Kees Koedooder, Cristina Lavini, Cornelis JF Van Noorden, Jaap Haveman, William P Vandertop and Wouter R van Furth
    Citation: Radiation Oncology 2007 2:38
  16. Accelerated partial breast irradiation is commonly done with the MammoSite applicator, which requires symmetry to treat the patient. This paper describes three cases that were asymmetric when initially placed ...

    Authors: Subhakar Mutyala, Walter Choi, Atif J Khan, Ravi Yaparpalvi, Alexandra J Stewart and Phillip M Devlin
    Citation: Radiation Oncology 2007 2:37
  17. To assess the feasibility and early toxicity of selective, IMRT-based dose escalation (simultaneous integrated boost) to biopsy proven dominant intra-prostatic lesions visible on MRI.

    Authors: Anurag K Singh, Peter Guion, Nancy Sears-Crouse, Karen Ullman, Sharon Smith, Paul S Albert, Gabor Fichtinger, Peter L Choyke, Sheng Xu, Jochen Kruecker, Bradford J Wood, Axel Krieger and Holly Ning
    Citation: Radiation Oncology 2007 2:36
  18. To compare non coplanar field (NCF) with coplanar field (CF) -intensity-modulated radiotherapy (IMRT) planning for ethmoid cancer.

    Authors: Antoine Serre, Katia Idri, Pascal Fenoglietto, Norbert Ailleres, Lore Santoro, Claire Lemanski, Renaud Garrel, Marc Makeieff, Ali Allaw, Jean-Bernard Dubois and David Azria
    Citation: Radiation Oncology 2007 2:35
  19. To evaluate the effects of direct machine parameter optimization in the treatment planning of intensity-modulated radiation therapy (IMRT) for hypopharyngeal cancer as compared to subsequent leaf sequencing in...

    Authors: Barbara Dobler, Fabian Pohl, Ludwig Bogner and Oliver Koelbl
    Citation: Radiation Oncology 2007 2:33
  20. Respiration-gated radiotherapy (RGRT) can decrease treatment toxicity by allowing for smaller treatment volumes for mobile tumors. RGRT is commonly performed using external surrogates of tumor motion. We descr...

    Authors: John R van Sörnsen de Koste, Johan P Cuijpers, Frank GM de Geest, Frank J Lagerwaard, Ben J Slotman and Suresh Senan
    Citation: Radiation Oncology 2007 2:32
  21. Oncological results of radiotherapy for locally advanced prostate cancer (PC) are significantly improved by simultaneous application of LHRH analoga (e.g. goserelin). As 85% of PC express LHRH receptors, we in...

    Authors: Robert M Hermann, Dag Schwarten, Stefanie Fister, Carsten Grundker, Margret Rave-Frank, Mirko Nitsche, Andrea Hille, Paul Thelen, Heinz Schmidberger and Hans Christiansen
    Citation: Radiation Oncology 2007 2:31
  22. Smoking is an important risk factor for the development of cancer. Smoking during radiochemotherapy therapy may have a negative influence on prognosis. We evaluated the effect of smoking during radiochemothera...

    Authors: Sabine Kathrin Mai, Grit Welzel, Verena Haegele and Frederik Wenz
    Citation: Radiation Oncology 2007 2:30
  23. To assess acute (primary endpoint) and late toxicity, quality of life (QOL), biochemical or clinical failure (secondary endpoints) of a hypofractionated IMRT schedule for prostate cancer (PC).

    Authors: Sara Junius, Karin Haustermans, Barbara Bussels, Raymond Oyen, Bianca Vanstraelen, Tom Depuydt, Jan Verstraete, Steven Joniau and Hendrik Van Poppel
    Citation: Radiation Oncology 2007 2:29
  24. Results of high-dose chemo-radiotherapy (CRT), using the treatment schedules of EORTC study 08972/22973 or radiotherapy (RT) alone were analyzed among all patients (pts) with Non Small Cell Lung Cancer (NSCLC)...

    Authors: Apollonia LJ Uitterhoeve, Mia GJ Koolen, Rob M van Os, Kees Koedooder, Marlou van de Kar, Bradley R Pieters and Caro CE Koning
    Citation: Radiation Oncology 2007 2:27
  25. Intensity-modulated radiation therapy (IMRT) affords unparalleled capacity to deliver conformal radiation doses to tumors in the central nervous system. However, to date, there are few reported outcomes from u...

    Authors: Clifton D Fuller, Mehee Choi, Britta Forthuber, Samuel J Wang, Nancy Rajagiriyil, Bill J Salter and Martin Fuss
    Citation: Radiation Oncology 2007 2:26
  26. The ATM protein is activated as a result of ionizing radiation, and genetic variants of the ATM gene may therefore affect the level of radiation-induced damage. Individuals heterozygous for ATM mutations have bee...

    Authors: Hege Edvardsen, Toril Tefre, Laila Jansen, Phuong Vu, Bruce G Haffty, Sophie D Fosså, Vessela N Kristensen and Anne-Lise Børresen-Dale
    Citation: Radiation Oncology 2007 2:25
  27. Several experimental strategies of radiation-induced central nervous system toxicity prevention have recently resulted in encouraging data. The present review summarizes the background for this research and th...

    Authors: Carsten Nieder, Nicolaus Andratschke and Sabrina T Astner
    Citation: Radiation Oncology 2007 2:23
  28. To determine the usefulness of dose volume histogram (DVH) factors for predicting the occurrence of radiation pneumonitis (RP) after application of stereotactic radiation therapy (SRT) for lung tumors, DVH fac...

    Authors: Hideomi Yamashita, Keiichi Nakagawa, Naoki Nakamura, Hiroki Koyanagi, Masao Tago, Hiroshi Igaki, Kenshiro Shiraishi, Nakashi Sasano and Kuni Ohtomo
    Citation: Radiation Oncology 2007 2:21
  29. Fibrosis is a common side effect after treatment with ionizing radiation. Several methods to ameliorate debilitating fibrosis have been employed but without consistent results. The goal of this pilot study is ...

    Authors: Nicole L Simone, Benjamin P Soule, Lynn Gerber, Elizabeth Augustine, Sharon Smith, Rosemary M Altemus, James B Mitchell and Kevin A Camphausen
    Citation: Radiation Oncology 2007 2:19
  30. To correlate the metabolic changes with size changes for tumor response by concomitant PET-CT evaluation of lung cancers after radiotherapy.

    Authors: Ching-yee O Wong, Joseph Schmidt, Jeffery S Bong, Suyra Chundru, Larry Kestin, Di Yan, Inga Grills, Marianne Gaskill, Vincent Cheng, Alvaro A Martinez and Darlene Fink-Bennett
    Citation: Radiation Oncology 2007 2:18
  31. Treatment guidelines recommend that curative radiation treatment of prostate cancer be offered only to men whose life expectancy is greater than 10 years. The average life expectancy of North American males is...

    Authors: Paul A Blood and Tom Pickles
    Citation: Radiation Oncology 2007 2:17
  32. Except for early T1,2 N0 stages, the prognosis for patients with oral cavity cancer (OCC) is reported to be worse than for carcinoma in other sites of the head and neck (HNC). The aim of this work was to asses...

    Authors: Gabriela Studer, Roger A Zwahlen, Klaus W Graetz, Bernard J Davis and Christoph Glanzmann
    Citation: Radiation Oncology 2007 2:16
  33. Carcinoma of the prostate gland is the most frequent malignant tumour affecting male population. While the large majority of tumours is represented by adenocarcinoma, pure squamous cell carcinoma comprises onl...

    Authors: Fernando Munoz, Pierfrancesco Franco, Patrizia Ciammella, Mario Clerico, Mauro Giudici, Andrea Riccardo Filippi and Umberto Ricardi
    Citation: Radiation Oncology 2007 2:15
  34. Intraoperative Radiotherapy (IORT) is a method by which a critical radiation dose is delivered to the tumour bed immediately after surgical excision. It is being investigated whether a single high dose of radi...

    Authors: Kris S Armoogum, John M Parry, Salam K Souliman, David G Sutton and Colin D Mackay
    Citation: Radiation Oncology 2007 2:11
  35. To evaluate the pathologic response of cervical carcinoma to external beam radiotherapy (EBRT) and high dose rate brachytherapy (HDRB) and outcome.

    Authors: Alexandre A Jacinto, Marcus S Castilho, Paulo ERS Novaes, Pablo R Novick, Gustavo A Viani, João V Salvajoli, Robson Ferrigno, Antonio Cássio A Pellizzon, Stella SS Lima, Maria AC Maia and Ricardo C Fogaroli
    Citation: Radiation Oncology 2007 2:9
  36. To evaluate the results of salvage conformal radiation therapy (3DC-EBRT) for patients submitted to radical prostatectomy (RP) who have achieved complete PSA response and who have never been treated with hormo...

    Authors: Alexandre A Jacinto, Angelo BS Fede, Lívia A Fagundes, João V Salvajoli, Marcus S Castilho, Gustavo A Viani, Ricardo C Fogaroli, Paulo ERS Novaes, Antonio Cássio A Pellizzon, Maria AC Maia and Robson Ferrigno
    Citation: Radiation Oncology 2007 2:8
  37. To evaluate the performance of seven different TPS (Treatment Planning Systems: Corvus, Eclipse, Hyperion, KonRad, Oncentra Masterplan, Pinnacle and PrecisePLAN) when intensity modulated (IMRT) plans are desig...

    Authors: Antonella Fogliata, Giorgia Nicolini, Markus Alber, Mats Åsell, Alessandro Clivio, Barbara Dobler, Malin Larsson, Frank Lohr, Friedlieb Lorenz, Jan Muzik, Martin Polednik, Eugenio Vanetti, Dirk Wolff, Rolf Wyttenbach and Luca Cozzi
    Citation: Radiation Oncology 2007 2:7
  38. To report the toxicity after intensity modulated radiotherapy (IMRT) for patients with localized prostate cancer, as a sole treatment or after radical prostatectomy.

    Authors: Michael J Chen, Eduardo Weltman, Rodrigo M Hanriot, Fábio P Luz, Paulo J Cecílio, José C da Cruz, Frederico R Moreira, Adriana S Santos, Lidiane C Martins and Wladmir Nadalin
    Citation: Radiation Oncology 2007 2:6
  39. Platelet-derived growth factor (PDGF) was originally identified as a constituent of blood serum and subsequently purified from human platelets. PDGF ligand is a dimeric molecule consisting of two disulfide-bon...

    Authors: Minglun Li, Verena Jendrossek and Claus Belka
    Citation: Radiation Oncology 2007 2:5
  40. Common complications of thoracic radiotherapy include esophagitis and radiation pneumonitis. However, it is important to be aware of uncommon post-radiotherapy complications such as bronchiolitis obliterans or...

    Authors: Robin Cornelissen, Suresh Senan, Imogeen E Antonisse, Hauw Liem, Youke KY Tan, Arjan Rudolphus and Joachim GJV Aerts
    Citation: Radiation Oncology 2007 2:2

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