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  1. A new-generation low-energy linear accelerator (UNIQUE) was introduced in the clinical arena during 2009 by Varian Medical Systems. The world's first UNIQUE was installed at Oncology Institute of Southern Swit...

    Authors: Alessandro Clivio, Giorgia Nicolini, Eugenio Vanetti, Antonella Fogliata and Luca Cozzi
    Citation: Radiation Oncology 2011 6:129
  2. Temporal lobe necrosis (TLN) is the most debilitating late-stage complication after radiation therapy in patients with nasopharyngeal cancer (NPC). The bilateral temporal lobes are inevitably encompassed in th...

    Authors: Jing Chen, Meera Dassarath, Zhongyuan Yin, Hongli Liu, Kunyu Yang and Gang Wu
    Citation: Radiation Oncology 2011 6:128
  3. Postoperative chemoradiation as per Intergroup-0116 trial ("Macdonald regimen") is considered standard for completely resected high risk gastric cancer. However, many concerns remain with regards to the toxici...

    Authors: Yulia Kundel, Ofer Purim, Efraim Idelevich, Konstantin Lavrenkov, Sofia Man, Svetlana Kovel, Natalia Karminsky, Raphael M Pfeffer, Bella Nisenbaum, Eyal Fenig, Aaron Sulkes and Baruch Brenner
    Citation: Radiation Oncology 2011 6:127
  4. The role of adjuvant chemoradiation therapy for ampullary carcinoma is unknown. Previous literature suggests that certain populations with high risk factors for recurrence may benefit from adjuvant chemoradiat...

    Authors: Amol K Narang, Robert C Miller, Charles C Hsu, Sumita Bhatia, Timothy M Pawlik, Dan Laheru, Ralph H Hruban, Jessica Zhou, Jordan M Winter, Michael G Haddock, John H Donohue, Richard D Schulick, Christopher L Wolfgang, John L Cameron and Joseph M Herman
    Citation: Radiation Oncology 2011 6:126
  5. The aim of the present study was to evaluate the recovery potential of the parotid glands after using either 3D-conformal-radiotherapy (3D-CRT) or intensity-modulated radiotherapy (IMRT) by sparing one single ...

    Authors: Jeremias Hey, Juergen Setz, Reinhard Gerlach, Martin Janich, Guido Hildebrandt, Dirk Vordermark, Christian R Gernhardt and Thomas Kuhnt
    Citation: Radiation Oncology 2011 6:125
  6. To explore possible improvement in the treatment of locally advanced pancreatic carcinoma (LAPC) we performed a randomized, non-comparative phase II study evaluating docetaxel - plus either daily continuous 5 ...

    Authors: Lucie Oberic, Frédéric Viret, Charlotte Baey, Marc Ychou, Jaafar Bennouna, Antoine Adenis, Didier Peiffert, Françoise Mornex, Jean-Pierre Pignon, Patrice Celier, Jocelyne Berille and Michel Ducreux
    Citation: Radiation Oncology 2011 6:124
  7. Several investigations have recently suggested the existence of a correlation between the dose received by the penile bulb (PB) and the risk of erectile dysfunction (ED) after radical radiotherapy for clinical...

    Authors: Lucia Perna, Cesare Cozzarini, Eleonora Maggiulli, Gianni Fellin, Tiziana Rancati, Riccardo Valdagni, Vittorio Vavassori, Sergio Villa and Claudio Fiorino
    Citation: Radiation Oncology 2011 6:123
  8. To report our experience on disease control and functional outcome using three modern combined-modality approaches for definitive radiochemotherapy of locally advanced SCCHN with modern radiotherapy techniques...

    Authors: Alexandra D Jensen, Jürgen Krauss, Wilko Weichert, Zazie P Bergmann, Kolja Freier, Jürgen Debus and Marc W Münter
    Citation: Radiation Oncology 2011 6:122
  9. Early and accurate prediction of response to cancer treatment through imaging criteria is particularly important in rapidly progressive malignancies such as Glioblastoma Multiforme (GBM). We sought to assess t...

    Authors: Adam Gladwish, Eng-Siew Koh, Jeremy Hoisak, Gina Lockwood, Barbara-Ann Millar, Warren Mason, Eugene Yu, Normand J Laperriere and Cynthia Ménard
    Citation: Radiation Oncology 2011 6:121
  10. Former prospective analyses revealed gross tumor volume (GTV) as the most reliable parameter to statistically significantly predict disease control in head neck cancer (HNC) patients treated with definitive in...

    Authors: Gabriela Studer, Tamara Rordorf and Christoph Glanzmann
    Citation: Radiation Oncology 2011 6:120
  11. The pan-HDAC inhibitor (HDACI) suberoylanilide hydroxamic acid (SAHA) has previously shown to be a radio-sensitizer to conventional photon radiotherapy (XRT) in pediatric sarcoma cell lines. Here, we investiga...

    Authors: Susanne Oertel, Markus Thiemann, Karsten Richter, Klaus-J Weber, Peter E Huber, Ramon Lopez Perez, Stephan Brons, Marc Bischof, Andreas E Kulozik, Volker Ehemann, Jürgen Debus and Claudia Blattmann
    Citation: Radiation Oncology 2011 6:119
  12. As part of French residents' radiotherapy training, delineation workstations were available at a national teaching course. We report a prospective comparative study of a non small cell lung cancer (NSCLC) case...

    Authors: Sylvain Dewas, Jean-Emmanuel Bibault, Pierre Blanchard, Claire Vautravers-Dewas, Yoann Pointreau, Fabrice Denis, Michel Brauner and Philippe Giraud
    Citation: Radiation Oncology 2011 6:118
  13. We analyzed our long-term experience with fractionated stereotactic radiotherapy (FSRT) in patients with meningioma of the optic nerve sheath (ONSM).

    Authors: Sebastian Adeberg, Thomas Welzel, Stefan Rieken, Jürgen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2011 6:117
  14. Chordoma, a rare cancer, is usually treated with surgery and/or radiation. However, very limited characterizations of chordoma cells are available due to a minimal availability (only two lines validated by now...

    Authors: Takamitsu A Kato, Akihisa Tsuda, Mitsuru Uesaka, Akira Fujimori, Tadashi Kamada, Hirohiko Tsujii and Ryuichi Okayasu
    Citation: Radiation Oncology 2011 6:116
  15. A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate de...

    Authors: Stephanie E Combs, Stefan Rieken, Wolfgang Wick, Amir Abdollahi, Andreas von Deimling, Jürgen Debus and Christian Hartmann
    Citation: Radiation Oncology 2011 6:115
  16. KRAS mutations may predict poor response to radiotherapy. Downstream events from KRAS, such as activation of BRAF, AKT and ERK, may also confer prognostic information but have not been tested in rectal cancer (RC...

    Authors: Janine M Davies, Dimitri Trembath, Allison M Deal, William K Funkhouser, Benjamin F Calvo, Timothy Finnegan, Karen E Weck, Joel E Tepper and Bert H O'Neil
    Citation: Radiation Oncology 2011 6:114
  17. To test feasibility and safety of clinical usage of Flattening Filter Free (FFF) beams for delivering ablative stereotactic body radiation therapy (SBRT) doses to various tumor sites, by means of Varian TrueBe...

    Authors: Marta Scorsetti, Filippo Alongi, Simona Castiglioni, Alessandro Clivio, Antonella Fogliata, Francesca Lobefalo, Pietro Mancosu, Pierina Navarria, Valentina Palumbo, Chiara Pellegrini, Sara Pentimalli, Giacomo Reggiori, Anna M Ascolese, Antonella Roggio, Stefano Arcangeli, Angelo Tozzi…
    Citation: Radiation Oncology 2011 6:113
  18. Increasing clinical data supports a low α/β ratio for prostate adenocarcinoma, potentially lower than that of surrounding normal tissues. A hypofractionated, weekly radiation therapy (RT) schedule should resul...

    Authors: Cathy Menkarios, Éric Vigneault, Nicolas Brochet, David HA Nguyen, Jean-Paul Bahary, Marjory Jolicoeur, Marie-Claude Beauchemin, Hugo Villeneuve, Thu Van Nguyen, Bernard Fortin and Carole Lambert
    Citation: Radiation Oncology 2011 6:112
  19. Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas), the combination of this agent with c...

    Authors: Matthias Bache, Martin P Zschornak, Sarina Passin, Jacqueline Keßler, Henri Wichmann, Matthias Kappler, Reinhard Paschke, Goran N Kaluđerović, Harish Kommera, Helge Taubert and Dirk Vordermark
    Citation: Radiation Oncology 2011 6:111
  20. Prostate bed (PB) contouring is time consuming and associated with inter-observer variability. We evaluated an automated atlas-based segmentation (AABS) engine in its potential to reduce contouring time and in...

    Authors: Jeremiah Hwee, Alexander V Louie, Stewart Gaede, Glenn Bauman, David D'Souza, Tracy Sexton, Michael Lock, Belal Ahmad and George Rodrigues
    Citation: Radiation Oncology 2011 6:110
  21. Surgery after (chemo)radiation (RCTX/RTX) is felt to be plagued with a high incidence of wound healing complications reported to be as high as 70%. The additional use of vascularized flaps may help to decrease...

    Authors: Christian Simon, Cem Bulut, Philippe A Federspil, Marc W Münter, Katja Lindel, Zazie Bergmann, Serkan Sertel, Sarah Leitzbach and Peter K Plinkert
    Citation: Radiation Oncology 2011 6:109
  22. Radiotherapy technology is expanding rapidly. Volumetric Modulated Arc Therapy (VMAT) technologies such as RapidArc® (RA) may be a more efficient way of delivering intensity-modulated radiotherapy-like (IM) treat...

    Authors: Gerald B Fogarty, Diana Ng, Guilin Liu, Lauren E Haydu and Nastik Bhandari
    Citation: Radiation Oncology 2011 6:108
  23. To assess brachytherapy catheter positioning accuracy and to evaluate the effects of prolonged irradiation time on the tolerance dose of normal liver parenchyma following single-fraction irradiation with 192 Ir.

    Authors: Lutz Lüdemann, Christian Wybranski, Max Seidensticker, Konrad Mohnike, Siegfried Kropf, Peter Wust and Jens Ricke
    Citation: Radiation Oncology 2011 6:107
  24. Boron neutron capture reaction (BNCR) is based on irradiation of tumors after accumulation of boron compound. 10B captures neutrons and produces an alpha (4He) particle and a recoiled lithium nucleus (7Li). These...

    Authors: Yuko Kinashi, Sentaro Takahashi, Genro Kashino, Ryuichi Okayasu, Shinichiro Masunaga, Minoru Suzuki and Koji Ono
    Citation: Radiation Oncology 2011 6:106
  25. Preoperative capecitabine-based chemoradiation is a standard treatment for locally advanced rectal cancer (LARC). Here, we explored the safety and efficacy of the addition of bevacizumab to capecitabine and co...

    Authors: Vaneja Velenik, Janja Ocvirk, Maja Music, Matej Bracko, Franc Anderluh, Irena Oblak, Ibrahim Edhemovic, Erik Brecelj, Mateja Kropivnik and Mirko Omejc
    Citation: Radiation Oncology 2011 6:105
  26. Lung metastases arising from nasopharyngeal carcinomas (NPC) have a relatively favourable prognosis. The purpose of this study was to identify the prognostic factors and to establish a risk grouping in patient...

    Authors: Xun Cao, Rong-Zhen Luo, Li-Ru He, Yong Li, Wen-Qian Lin, You-Fang Chen and Zhe-Sheng Wen
    Citation: Radiation Oncology 2011 6:104
  27. A new algorithm for photon dose calculation, Acuros XB, has been recently introduced in the Eclipse, Varian treatment planning system, allowing, similarly to the classic Monte Carlo methods, for accurate model...

    Authors: Antonella Fogliata, Giorgia Nicolini, Alessandro Clivio, Eugenio Vanetti and Luca Cozzi
    Citation: Radiation Oncology 2011 6:103
  28. Radiation therapy plays a central role in the management of many childhood malignancies and Helical Tomotherapy (HT) provides potential to decrease toxicity by limiting the radiation dose to normal structures....

    Authors: Latifa Mesbah, Raúl Matute, Sergey Usychkin, Immacolata Marrone, Fernando Puebla, Cristina Mínguez, Rafael García, Graciela García, César Beltrán and Hugo Marsiglia
    Citation: Radiation Oncology 2011 6:102
  29. The purpose of the study was to evaluate the patient set-up error of different anatomical sites, to estimate the effect of different frequencies of online verifications on the patient set-up accuracy, and to c...

    Authors: Volker Rudat, Mohamed Hammoud, Yogin Pillay, Abdul Aziz Alaradi, Adel Mohamed and Saleh Altuwaijri
    Citation: Radiation Oncology 2011 6:101
  30. We have previously demonstrated that elevated concentrations of tumour-associated trypsin inhibitor (TATI) in both tumour tissue (t-TATI) and in serum (s-TATI) are associated with a poor prognosis in colorecta...

    Authors: Alexander Gaber, Christina Stene, Kristina Hotakainen, Björn Nodin, Ingrid Palmquist, Anders Bjartell, Ulf-Håkan Stenman, Bengt Jeppsson, Louis B Johnson and Karin Jirström
    Citation: Radiation Oncology 2011 6:100
  31. Choosing the most effective approach for treating rectal cancer with mesorectal fascia (MRF) involvement or closeness and synchronous distant metastases is a current clinical challenge. The aim of this retrosp...

    Authors: Sang Joon Shin, Hong In Yoon, Nam Kyu Kim, Kang Young Lee, Byung Soh Min, Joong Bae Ahn, Ki Chang Keum and Woong Sub Koom
    Citation: Radiation Oncology 2011 6:99
  32. Reirradiation is a feasible option for patients who do not otherwise have treatment options available. Depending on the location and extent of the tumor, reirradiation may be accomplished with external beam ra...

    Authors: Hideya Yamazaki, Naohiro Kodani, Mikio Ogita, Kengo Sato and Kengo Himei
    Citation: Radiation Oncology 2011 6:98
  33. Both epidemiological and experimental studies suggest that heterozygosity for a single gene is linked with tumorigenesis and heterozygosity for two genes increases the risk of tumor incidence. Our previous wor...

    Authors: Jufang Wang, Fengtao Su, Lubomir B Smilenov, Libin Zhou, Wentao Hu, Nan Ding and Guangming Zhou
    Citation: Radiation Oncology 2011 6:96
  34. To evaluate the experience of induction chemotherapy followed by concurrent chemoradiationwith helical tomotherapy (HT) for nasopharyngeal carcinoma (NPC).

    Authors: Pei-Wei Shueng, Bing-Jie Shen, Le-Jung Wu, Li-Jen Liao, Chi-Huang Hsiao, Yu-Chin Lin, Po-Wen Cheng, Wu-Chia Lo, Yee-Min Jen and Chen-Hsi Hsieh
    Citation: Radiation Oncology 2011 6:95
  35. A patient with anaplastic meningioma and lung metastases resistant to conventional treatment underwent radiopeptide therapy with 177Lu- DOTA-octreotate in our institute. The treatment resulted in significant i...

    Authors: Amir Sabet, Hojjat Ahmadzadehfar, Ulrich Herrlinger, Winfried Wilinek, Hans-Jürgen Biersack and Samer Ezziddin
    Citation: Radiation Oncology 2011 6:94
  36. Positive correlation between caseload and outcome has previously been validated for several procedures and cancer treatments. However, there is no information linking caseload and outcome of nasopharyngeal car...

    Authors: Ching-Chih Lee, Tze-Ta Huang, Moon-Sing Lee, Yu-Chieh Su, Pesus Chou, Shih-Hsuan Hsiao, Wen-Yen Chiou, Hon-Yi Lin, Sou-Hsin Chien and Shih-Kai Hung
    Citation: Radiation Oncology 2011 6:92
  37. Neoadjuvant chemoradiation (NCR) prior to resection of extremity soft tissue sarcoma (STS) has been studied, but data are limited. We present outcomes with NCR using a variety of chemotherapy regimens compared...

    Authors: Kelly K Curtis, Jonathan B Ashman, Christopher P Beauchamp, Adam J Schwartz, Matthew D Callister, Amylou C Dueck, Leonard L Gunderson and Tom R Fitch
    Citation: Radiation Oncology 2011 6:91
  38. Pure seminoma is a rare pathology of the young adult, often discovered in the early stages. Its prognosis is generally excellent and many therapeutic options are available, especially in stage I tumors. High c...

    Authors: Noureddine Boujelbene, Adrien Cosinschi, Nadia Boujelbene, Kaouthar Khanfir, Shushila Bhagwati, Eveleyn Herrmann, Rene-Olivier Mirimanoff, Mahmut Ozsahin and Abderrahim Zouhair
    Citation: Radiation Oncology 2011 6:90
  39. Over the last years an increasing incidence of Clostridium difficile-associated diarrhea (CDAD) has been reported. Especially haematology-oncology patients are at risk of developing CDAD.

    Authors: Matthias G Hautmann, Matthias Hipp and Oliver Kölbl
    Citation: Radiation Oncology 2011 6:89
  40. Despite of a growing number of gemcitabine based chemoradiotherapy studies in locally advanced pancreatic cancer (LAPC), 5-fluorouracil based regimens are still regarded to be standard and the debate of superi...

    Authors: Thomas B Brunner, Rolf Sauer and Rainer Fietkau
    Citation: Radiation Oncology 2011 6:88
  41. Our research compared whole pelvic (WP) and prostate-only (PO) 3-dimensional conformal radiotherapy (3DCRT) techniques in terms of the incidence and evolution of acute and late toxicity of the rectum and urina...

    Authors: Jana Vranova, Stepan Vinakurau, Jan Richter, Miroslav Starec, Anna Fiserova and Jozef Rosina
    Citation: Radiation Oncology 2011 6:87
  42. Two major ways of macrophage (MΦ) activation can occur in radiation-induced pulmonary injury (RPI): classical and alternative MΦ activation, which play important roles in the pathogenesis of RPI. MΦ can produc...

    Authors: Zhongshi He, Hui Zhang, Chunxu Yang, Yajuan Zhou, Yong Zhou, Guang Han, Ling Xia, Wen Ouyang, Fuxiang Zhou, Yunfeng Zhou and Conghua Xie
    Citation: Radiation Oncology 2011 6:86
  43. To present the results of quality assurance (QA) in IMRT of film dosimetry and ionization chambers measurements with an eight year follow-up.

    Authors: Pascal Fenoglietto, Benoit Laliberté, Norbert Aillères, Olivier Riou, Jean-Bernard Dubois and David Azria
    Citation: Radiation Oncology 2011 6:85
  44. To evaluate the clinical efficacy and toxicity of stereotactic body radiation therapy (SBRT) using extracranial gamma knife in patients with mainly bulky inoperable early stage non-small cell lung carcinoma (N...

    Authors: Dajun Wu, Hong Zhu, Hanjun Tang, Changlin Li and Feng Xu
    Citation: Radiation Oncology 2011 6:84
  45. We propose a planning method to design true 4-dimensional (4D) intensity-modulated radiotherapy (IMRT) plans, called the t4Dplan method, in which the planning target volume (PTV) of the individual phases of th...

    Authors: Xiaoqiang Li, Xiaochun Wang, Yupeng Li and Xiaodong Zhang
    Citation: Radiation Oncology 2011 6:83
  46. Preoperative radiotherapy and chemotherapy in patients with head and neck cancer result in changes to the vessels that are used to construct microsurgical anastomoses. The aim of the study was to investigate q...

    Authors: Frank Tavassol, Horst Kokemüller, Rüdiger Zimmerer, Nils-Claudius Gellrich and André Eckardt
    Citation: Radiation Oncology 2011 6:81
  47. Standard therapy for metastatic non small cell lung cancer (NSCLC) includes palliative systemic chemotherapy and/or radiotherapy. Recent studies of patients with limited metastases treated with curative-intent...

    Authors: Praveena Cheruvu, Su K Metcalfe, Justin Metcalfe, Yuhchyau Chen, Paul Okunieff and Michael T Milano
    Citation: Radiation Oncology 2011 6:80

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