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  1. A large increase in nitric oxide fraction (FeNO) after radiotherapy (RT) for lung cancer may predict RT-induced lung toxicity.

    Authors: Irina Enache, Georges Noel, M-Young Jeung, Nicolas Meyer, Monique Oswald-Mammosser, Emile Urban-Kraemer, Catherine Schumacher, Bernard Geny, Elisabeth Quoix and Anne Charloux
    Citation: Radiation Oncology 2012 7:117
    Content type: Research Published on:

  2. For many decades, the standard of care radiotherapy regimen for medulloblastoma has been photon (megavoltage x-rays) craniospinal irradiation (CSI). The late effects associated with CSI are well-documented in ...

    Authors: Rebecca M Howell, Annelise Giebeler, Wendi Koontz-Raisig, Anita Mahajan, Carol J Etzel, Anthony M D’Amelio Jr, Kenneth L Homann and Wayne D Newhauser
    Citation: Radiation Oncology 2012 7:116
    Content type: Research Published on:

  3. To establish a common database on particle therapy for the evaluation of clinical studies integrating a large variety of voluminous datasets, different documentation styles, and various information systems, es...

    Authors: Kerstin A Kessel, Nina Bougatf, Christian Bohn, Daniel Habermehl, Dieter Oetzel, Rolf Bendl, Uwe Engelmann, Roberto Orecchia, Piero Fossati, Richard Pötter, Manjit Dosanjh, Jürgen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2012 7:115
    Content type: Research Published on:

  4. Locoregional recurrence is the typical pattern of recurrence in gastric cancer, and cannot be removed by surgery in most of the patients. We aimed to evaluate the feasibility and efficacy of computed tomograph...

    Authors: Liangrong Shi, Changping Wu, Jun Wu, Wenjie Zhou, Mei Ji, Hongyu Zhang, Jiemin Zhao, Yuanquan Huang, Honglei Pei, Zhong Li, Jingfang Ju and Jingting Jiang
    Citation: Radiation Oncology 2012 7:114
    Content type: Research Published on:

  5. Photodynamic therapy (PDT) is a less invasive and effective salvage treatment for local failure after chemoradiotherapy (CRT) for esophageal cancer, however it causes a high rate of skin phototoxicity and requ...

    Authors: Tomonori Yano, Manabu Muto, Kenichi Yoshimura, Miyuki Niimi, Yasumasa Ezoe, Yusuke Yoda, Yoshinobu Yamamoto, Hogara Nishisaki, Koji Higashino and Hiroyasu Iishi
    Citation: Radiation Oncology 2012 7:113
    Content type: Research Published on:

  6. The treatment strategy of central lung tumors is not established. Intraluminal brachytherapy (ILBT) is widely used for palliative treatment of endobronchial tumors, however, it is also a promising option for c...

    Authors: Hidemasa Kawamura, Takeshi Ebara, Hiroyuki Katoh, Tomoaki Tamaki, Hitoshi Ishikawa, Hideyuki Sakurai and Takashi Nakano
    Citation: Radiation Oncology 2012 7:112
    Content type: Research Published on:

  7. To compare 3 Dimensional Conformal radiotherapy (3D-CRT) with Intensity Modulated Radiotherapy (IMRT) with Volumetric-Modulated Arc Therapy (VMAT) for bladder cancer.

    Authors: Farshad Foroudi, Lesley Wilson, Mathias Bressel, Annette Haworth, Colin Hornby, Daniel Pham, Jim Cramb, Suki Gill, Keen Hun Tai and Tomas Kron
    Citation: Radiation Oncology 2012 7:111
    Content type: Research Published on:

  8. Patients with locally advanced or recurrent rectal cancer often require multimodality treatment. Intraoperative radiation therapy (IORT) is a focal approach which aims to improve local control.

    Authors: Susan Guo, Chandana A Reddy, Matthew Kolar, Neil Woody, Arul Mahadevan, F Christopher Deibel, David W Dietz, Feza H Remzi and John H Suh
    Citation: Radiation Oncology 2012 7:110
    Content type: Research Published on:

  9. To proof feasibility of hydrogel application in patients with advanced cervical cancer undergoing chemo-radiation in order to reduce rectal toxicity from external beam radiation as well as brachytherapy.

    Authors: Simone Marnitz, Volker Budach, Friederike Weißer, Elena Burova, Bernhard Gebauer, Filiberto Guiseppe Vercellino and Christhardt Köhler
    Citation: Radiation Oncology 2012 7:109
    Content type: Short report Published on:

  11. Brainstem metastases represent an uncommon clinical presentation that is associated with a poor prognosis. Treatment options are limited given the unacceptable risks associated with surgical resection in this ...

    Authors: Jonathan E Leeman, David A Clump, Rodney E Wegner, Dwight E Heron, Steven A Burton and Arlan H Mintz
    Citation: Radiation Oncology 2012 7:107
    Content type: Research Published on:

  12. To evaluate the metabolic changes on 18 F-fluoro-2-deoxyglucose positron emission tomography integrated with computed tomography (18 F-FDG PET-CT) performed before, during and after concurrent chemo-radiotherapy ...

    Authors: Mariangela Massaccesi, Maria Lucia Calcagni, Maria Grazia Spitilli, Fabrizio Cocciolillo, Francesca Pelligrò, Lorenzo Bonomo, Vincenzo Valentini and Alessandro Giordano
    Citation: Radiation Oncology 2012 7:106
    Content type: Research Published on:

  13. Several studies have confirmed the advantages of delivering high doses of external beam radiotherapy to achieve optimal tumor-control outcomes in patients with localized prostate cancer. We evaluated the mediu...

    Authors: Ken Takeda, Yoshihiro Takai, Kakutaro Narazaki, Masatoshi Mitsuya, Rei Umezawa, Noriyuki Kadoya, Yukio Fujita, Toshiyuki Sugawara, Masaki Kubozono, Eiji Shimizu, Keiko Abe, Yuko Shirata, Yohjiro Ishikawa, Takaya Yamamoto, Maiko Kozumi, Suguru Dobashi…
    Citation: Radiation Oncology 2012 7:105
    Content type: Research Published on:

  14. The purpose of the present study was to analyze the recurrence pattern of high-grade glioma treated with a multimodal treatment approach and to evaluate whether the MIB-1 labeling index (LI) could be a useful ...

    Authors: Kazuyuki Uehara, Takashi Sasayama, Daisuke Miyawaki, Hideki Nishimura, Kenji Yoshida, Yoshiaki Okamoto, Naritoshi Mukumoto, Hiroaki Akasaka, Masamitsu Nishihara, Osamu Fujii, Toshinori Soejima, Kazuro Sugimura, Eiji Kohmura and Ryohei Sasaki
    Citation: Radiation Oncology 2012 7:104
    Content type: Research Published on:

  15. To analyze long-term results of radiotherapy alone for stage I-III low grade follicular lymphoma and to compare outcome after extended field irradiation (EFI) and total nodal irradiation (TNI).

    Authors: Matthias Guckenberger, Nikolaus Alexandrow and Michael Flentje
    Citation: Radiation Oncology 2012 7:103
    Content type: Research Published on:

  16. Stereotactic body radiation therapy (SBRT) for early-stage lung cancer can be achieved with several methods: respiratory gating, body frame, or real-time target and motion tracking. Two target tracking methods...

    Authors: Jean-Emmanuel Bibault, Bernard Prevost, Eric Dansin, Xavier Mirabel, Thomas Lacornerie and Eric Lartigau
    Citation: Radiation Oncology 2012 7:102
    Content type: Research Published on:

  19. External beam radiotherapy (EBRT) is the treatment of choice for irresectable meningioma. Due to the strong expression of somatostatin receptors, peptide receptor radionuclide therapy (PRRT) has been used in a...

    Authors: Michael C Kreissl, Heribert Hänscheid, Mario Löhr, Frederik A Verburg, Markus Schiller, Michael Lassmann, Christoph Reiners, Samuel S Samnick, Andreas K Buck, Michael Flentje and Reinhart A Sweeney
    Citation: Radiation Oncology 2012 7:99
    Content type: Research Published on:

  20. The respiratory related target motion and setup error will lead to a large margin in the gastric radiotherapy. The purpose of this study is to investigate the dosimetric benefit and the possibility of incorpor...

    Authors: Weigang Hu, Jinsong Ye, Jiazhou Wang, Qing Xu and Zhen Zhang
    Citation: Radiation Oncology 2012 7:98
    Content type: Research Published on:

  21. The OneDosePlusTM system, based on MOSFET solid-state radiation detectors and a handheld dosimetry reader, has been used to evaluate intra-fraction movements of patients with breast and prostate cancer.

    Authors: Maria Daniela Falco, Marco D’Andrea, Alessia Lo Bosco, Mauro Rebuzzi, Elisabetta Ponti, Barbara Tolu, Grazia Tortorelli, Rosaria Barbarino, Luana Di Murro and Riccardo Santoni
    Citation: Radiation Oncology 2012 7:97
    Content type: Research Published on:

  22. Artemis has a defined role in V(D)J recombination and has been implicated in the repair of radiation induced double-strand breaks. However the exact function(s) of Artemis in DNA repair and its preferred subst...

    Authors: Deepa M Sridharan, Mary K Whalen, Donna Almendrala, Francis A Cucinotta, Misako Kawahara, Steven M Yannone and Janice M Pluth
    Citation: Radiation Oncology 2012 7:96
    Content type: Research Published on:

  23. The optimal initial local treatment for patients with Graves’ ophthalmopathy (GO) is not fully characterized. The purpose of this retrospective study is to describe the clinical outcomes of RT as initial local...

    Authors: Roshan S Prabhu, Lang Liebman, Ted Wojno, Brent Hayek, William A Hall and Ian Crocker
    Citation: Radiation Oncology 2012 7:95
    Content type: Research Published on:

  24. Stereotactic brachytherapy (SBT) has been described in several publications as an effective, minimal invasive and safe highly focal treatment option in selected patients with well circumscribed brain tumors <4...

    Authors: Maximilian I Ruge, Philipp Kickingereder, Stefan Grau, Harald Treuer, Volker Sturm and Juergen Voges
    Citation: Radiation Oncology 2012 7:94
    Content type: Commentary Published on:

  26. Stereotactic Ablative Body Radiotherapy (SABR) is a non-invasive therapy option for inoperable liver oligometastases. Outcome and toxicity were retrospectively evaluated in a single-institution patient cohort ...

    Authors: Judit Boda-Heggemann, Dietmar Dinter, Christel Weiss, Anian Frauenfeld, Kerstin Siebenlist, Ulrike Attenberger, Martine Ottstadt, Frank Schneider, Ralf-Dieter Hofheinz, Frederik Wenz and Frank Lohr
    Citation: Radiation Oncology 2012 7:92
    Content type: Research Published on:

  27. The salivary mucin MUC5B, present in (sero)mucous secretions including submandibular gland (SMG) saliva, plays an important role in the lubrication of the oral mucosa and is thought to be related to the feelin...

    Authors: Tim Dijkema, Chris H J Terhaard, Judith M Roesink, Cornelis P J Raaijmakers, Petra A M van den Keijbus, Henk S Brand and Enno C I Veerman
    Citation: Radiation Oncology 2012 7:91
    Content type: Short report Published on:

  28. Adaptive Radiotherapy aims to identify anatomical deviations during a radiotherapy course and modify the treatment plan to maintain treatment objectives. This requires regions of interest (ROIs) to be defined ...

    Authors: Nicholas Hardcastle, Wolfgang A Tomé, Donald M Cannon, Charlotte L Brouwer, Paul WH Wittendorp, Nesrin Dogan, Matthias Guckenberger, Stéphane Allaire, Yogish Mallya, Prashant Kumar, Markus Oechsner, Anne Richter, Shiyu Song, Michael Myers, Bülent Polat and Karl Bzdusek
    Citation: Radiation Oncology 2012 7:90
    Content type: Research Published on:

  29. The aim of this study was to compare 64Cu-diacetyl-bis(N4-methylsemicarbazone) (64Cu-ATSM) and 18FDG PET uptake characteristics and 64Cu-ATSM autoradiography to pimonidazole immunohistochemistry in spontaneous ca...

    Authors: Anders E Hansen, Annemarie T Kristensen, Jesper T Jørgensen, Fintan J McEvoy, Morten Busk, Albert J van der Kogel, Johan Bussink, Svend A Engelholm and Andreas Kjær
    Citation: Radiation Oncology 2012 7:89
    Content type: Research Published on:

  30. To investigate the prognostic value of survivin expression in pretreatment specimens from patients with anal cancer treated with concurrent 5-FU and mitomycin C-based chemoradiation (CRT).

    Authors: Ingeborg Fraunholz, Claus Rödel, Luitpold Distel, Marget Rave-Fränk, Daniela Kohler, Stefan Falk and Franz Rödel
    Citation: Radiation Oncology 2012 7:88
    Content type: Research Published on:

  31. Radiation proctitis after intensity-modulated radiation therapy (IMRT) differs from that seen after pelvic irradiation in that this adverse event is a result of high-dose radiation to a very small area in the ...

    Authors: Shinya Takemoto, Yuta Shibamoto, Shiho Ayakawa, Aiko Nagai, Akihiro Hayashi, Hiroyuki Ogino, Fumiya Baba, Takeshi Yanagi, Chikao Sugie, Hiromi Kataoka and Mikio Mimura
    Citation: Radiation Oncology 2012 7:87
    Content type: Research Published on:

  32. Radiotherapy (RT) is widely used in the treatment of pancreatic cancer. Currently, recommendation has been given for the delineation of the clinical target volume (CTV) in adjuvant RT. Based on recently review...

    Authors: Luciana Caravatta, Giuseppina Sallustio, Fabio Pacelli, Gilbert DA Padula, Francesco Deodato, Gabriella Macchia, Mariangela Massaccesi, Vincenzo Picardi, Savino Cilla, Alfonso Marinelli, Numa Cellini, Vincenzo Valentini and Alessio G Morganti
    Citation: Radiation Oncology 2012 7:86
    Content type: Methodology Published on:

  33. The aim of this study was to report the long-term clinical outcomes of patients who received stereotactic body radiotherapy (SBRT) as a boost treatment for head and neck cancer.

    Authors: Dong Soo Lee, Yeon Sil Kim, Jae Seok Cheon, Jin Ho Song, Seok Hyun Son, Ji Sun Jang, Young Nam Kang, Jing Hyoung Kang, So Lyoung Jung, Ie Ryung Yoo and Hong Seok Jang
    Citation: Radiation Oncology 2012 7:85
    Content type: Research Published on:

  34. Except for early stages (T1/2 N0), the prognosis for patients with oral cavity cancer (OCC) is known to be worse than for those with pharyngeal carcinoma. While definitive intensity modulated radiation therapy...

    Authors: Gabriela Studer, Michelle Brown, Marius Bredell, Klaus W Graetz, Gerhard Huber, Claudia Linsenmeier, Yousef Najafi, Oliver Riesterer, Tamara Rordorf, Stephan Schmid and Christoph Glanzmann
    Citation: Radiation Oncology 2012 7:84
    Content type: Research Published on:

  35. Local control appears to be an important treatment aim in patients with limited metastases (oligometastases) of colorectal cancer (CRC). Those patients show a favourable prognosis, if - in addition to the loca...

    Authors: Kathrin Dellas, Thomas Reese, Michael Richter, Dirk Arnold and Jürgen Dunst
    Citation: Radiation Oncology 2012 7:83
    Content type: Research Published on:

  36. Low-risk prostate cancer (PCa) patients have excellent outcomes, with treatment modality often selected by perceived effects on quality of life. Acute urinary symptoms are common during external beam radiother...

    Authors: Jeffrey Vainshtein, Eyad Abu-Isa, Karin B Olson, Michael E Ray, Howard M Sandler, Dan Normolle, Dale W Litzenberg, Kathryn Masi, Charlie Pan and Daniel A Hamstra
    Citation: Radiation Oncology 2012 7:82
    Content type: Research Published on:

  37. To analyze the accuracy and inter-observer variability of image-guidance (IG) using 3D or 4D cone-beam CT (CBCT) technology in stereotactic body radiotherapy (SBRT) for lung tumors.

    Authors: Reinhart A Sweeney, Benedikt Seubert, Silke Stark, Vanessa Homann, Gerd Müller, Michael Flentje and Matthias Guckenberger
    Citation: Radiation Oncology 2012 7:81
    Content type: Review Published on:

  38. TomoBreast is a unicenter, non-blinded randomized trial comparing conventional radiotherapy (CR) vs. hypofractionated Tomotherapy (TT) for post-operative treatment of breast cancer. The purpose of the trial is...

    Authors: Hilde Van Parijs, Geertje Miedema, Vincent Vinh-Hung, Sylvia Verbanck, Nele Adriaenssens, Dirk Kerkhove, Truus Reynders, Daniel Schuermans, Katrien Leysen, Shane Hanon, Guy Van Camp, Walter Vincken, Guy Storme, Dirk Verellen and Mark De Ridder
    Citation: Radiation Oncology 2012 7:80
    Content type: Research Published on:

  39. Stereotactic lung radiotherapy (SLRT) has emerged as a curative treatment for medically inoperable patients with early-stage non-small cell lung cancer (NSCLC) and the use of intensity-modulated radiotherapy (...

    Authors: Jan Seppala, Sami Suilamo, Jarmo Kulmala, Pekka Mali and Heikki Minn
    Citation: Radiation Oncology 2012 7:79
    Content type: Research Published on:

  40. Concurrent radiochemotherapy is a recommended treatment option for patients with locally advanced squamous cell head and neck carcinomas with recent data showing the most significant absolute overall and event...

    Authors: Valentina Krstevska, Igor Stojkovski and Beti Zafirova-Ivanovska
    Citation: Radiation Oncology 2012 7:78
    Content type: Research Published on:

  41. Whole brain radiation therapy (WBRT) is an effective treatment in brain metastases and, when combined with local treatments such as surgery and stereotactic radiosurgery, gives the best brain control. Nonethel...

    Authors: Agnes V Tallet, David Azria, Fabrice Barlesi, Jean-Philippe Spano, Antoine F Carpentier, Antony Gonçalves and Philippe Metellus
    Citation: Radiation Oncology 2012 7:77
    Content type: Review Published on:

  42. Our purpose was to report acute gastrointestinal (GI) and genitourinary (GU) toxicity rates for prostate cancer patients undergoing image-guided intensity modulated radiation therapy (IG-IMRT) with a daily end...

    Authors: Curtiland Deville, Stefan Both, Viet Bui, Wei-Ting Hwang, Kay-See Tan, Mattia Schaer, Zelig Tochner and Neha Vapiwala
    Citation: Radiation Oncology 2012 7:76
    Content type: Research Published on:

  43. Radiotherapy (RT) and androgen-deprivation therapy (ADT) are standard treatments for advanced prostate cancer (PC). Tumor vascularization is recognized as an important physiological feature likely to impact on...

    Authors: Kathrine Røe, Lars TG Mikalsen, Albert J van der Kogel, Johan Bussink, Heidi Lyng, Anne H Ree, Laure Marignol and Dag R Olsen
    Citation: Radiation Oncology 2012 7:75
    Content type: Research Published on:

  44. Local control rates are poor in the treatment of pancreatic cancer. We investigated the role of hypofractionated stereotactic body radiation therapy (SBRT) for salvage or boost treatment after conventional dos...

    Authors: Chris E Lominska, Keith Unger, Nadim M Nasr, Nadim Haddad and Greg Gagnon
    Citation: Radiation Oncology 2012 7:74
    Content type: Research Published on:

  45. The primary objective of this research was to assess the relationship between FPs’ knowledge of palliative radiotherapy (RT) and referral for palliative RT.

    Authors: Robert A Olson, Sonca Lengoc, Scott Tyldesley, John French, Colleen McGahan and Jenny Soo
    Citation: Radiation Oncology 2012 7:73
    Content type: Research Published on:

  47. Earlier, we showed that in cancer cells, AMP-activated kinase (AMPK) participates in a signal transduction pathway involving ATM-AMPK-p53/p21cip1 which is activated by ionizing radiation (IR) to mediate G2-M arre...

    Authors: Yaryna Storozhuk, Toran Sanli, Sarah N Hopmans, Carrie Schultz, Tom Farrell, Jean-Claude Cutz, Gregory R Steinberg, James Wright, Gurmit Singh and Theodoros Tsakiridis
    Citation: Radiation Oncology 2012 7:71
    Content type: Research Published on:

  48. Quantitative analysis of transcriptional regulation of genes is a prerequisite for a better understanding of the molecular mechanisms of action of different radiation qualities such as photon, proton or carbon...

    Authors: Geeta D Sharungbam, Christian Schwager, Sara Chiblak, Stephan Brons, Lynn Hlatky, Thomas Haberer, Jürgen Debus and Amir Abdollahi
    Citation: Radiation Oncology 2012 7:70
    Content type: Research Published on:

  49. Radiation-induced lung injury (RILI) is an important dose-limiting toxicity during thoracic radiotherapy. The purpose of this study is to investigate single photon emission computed tomography (SPECT) perfusio...

    Authors: Dongqing Wang, Jinbo Sun, Jingyu Zhu, Xiaohong Li, Yanbo Zhen and Songtao Sui
    Citation: Radiation Oncology 2012 7:69
    Content type: Research Published on:

  50. To describe a pilot study for a novel preclinical model used to test human tissue-based therapies in the setting of cutaneous radiation injury.

    Authors: Lucas H Rifkin, Strahinja Stojadinovic, Collin H Stewart, Kwang H Song, Michael C Maxted, Marcus H Bell, Natalie S Kashefi, Michael P Speiser, Michel Saint-Cyr, Michael D Story, Rod J Rohrich, Spencer A Brown and Timothy D Solberg
    Citation: Radiation Oncology 2012 7:68
    Content type: Research Published on:
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Radiation Oncology

ISSN: 1748-717X

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