Articles

Impact of delays in radiotherapy of head and neck cancer on outcome

In head and neck cancer (HNC), the relationship between a delay in starting radiotherapy (RT) and the outcome is unclear. The aim of the present study was to determine the impact of the amount of time before t...

Authors: Barbara Žumer, Maja Pohar Perme, Simona Jereb and Primož Strojan

Intra-fraction and Inter-fraction analysis of a dedicated immobilization device for intracranial radiation treatment

Immobilization devices are crucial to minimize patient positioning uncertainties in radiotherapy (RT) treatments. Accurate inter and intra-fraction motions is particularly important for intracranial and stereo...

Authors: Chin Loon Ong, Niccolò Giaj-Levra, Luca Nicosia, Vanessa Figlia, Davide Tomasini, Eric M. Franken and Filippo Alongi

In regard to Cuccia et al.: impact of hydrogel peri-rectal spacer insertion on prostate gland intra-fraction motion during 1.5 T MR-guided stereotactic body radiotherapy

We read the article entitled “Impact of hydrogel peri-rectal spacer insertion on prostate gland intra-fraction motion during 1.5 T MR-guided stereotactic body radiotherapy” with great interest. In that study, ...

Authors: Hamed Ghaffari, Mahmoud Navaser and Soheila Refahi

Association between the 21-gene recurrence score and isolated locoregional recurrence in stage I-II, hormone receptor-positive breast cancer

Although the 21-gene recurrence score (RS) assay is widely used to predict distant recurrence risk and benefit from adjuvant chemotherapy among women with hormone receptor-positive (HR+) breast cancer, the rel...

Authors: David D. Yang, Daniela L. Buscariollo, Angel M. Cronin, Shicheng Weng, Melissa E. Hughes, Richard J. Bleicher, Adam L. Cohen, Sara H. Javid, Stephen B. Edge, Beverly Moy, Joyce C. Niland, Antonio C. Wolff, Michael J. Hassett and Rinaa S. Punglia

Oncometabolites and the response to radiotherapy

Radiotherapy (RT) is applied in 45–60% of all cancer patients either alone or in multimodal therapy concepts comprising surgery, RT and chemotherapy. However, despite technical innovations approximately only 5...

Authors: Kexu Xiang, Verena Jendrossek and Johann Matschke

Preservation of swallowing in resected oral cavity squamous cell carcinoma: examining radiation volume effects (PRESERVE): study protocol for a randomized phase II trial

Patients with resected oral cavity squamous cell carcinoma (OCSCC) are often treated with adjuvant radiation (RT) ± concomitant chemotherapy based on pathological findings. Standard RT volumes include all surg...

Authors: Pencilla Lang, Jessika Contreras, Noah Kalman, Claire Paterson, Houda Bahig, Astrid Billfalk-Kelly, Sinead Brennan, Kathy Rock, Nancy Read, Varagur Venkatesan, Jinka Sathya, Lucas C. Mendez, S. Danielle MacNeil, Anthony C. Nichols, Kevin Fung, Adrian Mendez…

Clinical impact of Hypofractionated carbon ion radiotherapy on locally advanced hepatocellular carcinoma

Hepatocellular carcinoma (HCC) involving a major branch of the portal or hepatic vein is in a locally advanced stage and remains difficult to cure. This study aimed to evaluate the clinical effects of carbon i...

Authors: Shintaro Shiba, Kei Shibuya, Masahiko Okamoto, Shohei Okazaki, Shuichiro Komatsu, Yoshiki Kubota, Takashi Nakano and Tatsuya Ohno

Missed radiation therapy sessions in first three weeks predict distant metastasis and less favorable outcomes in surgically treated patients with oral cavity squamous cell carcinoma

We sought to investigate the prognostic impact of missed RT sessions in patients who had undergone surgery for oral cavity squamous cell carcinoma (OCSCC).

Authors: Yin-Yin Chiang, Yung-Chih Chou, Kai-Ping Chang, Chun-Ta Liao, Yao-Yu Wu, Wing-Keen Yap, Ping-Ching Pai, Joseph Tung-Chieh Chang, Chien-Yu Lin, Kang-Hsing Fan, Bing-Shen Huang, Tsung-Min Hung and Ngan-Ming Tsang

A monocentric, open-label randomized standard-of-care controlled study of XONRID®, a medical device for the prevention and treatment of radiation-induced dermatitis in breast and head and neck cancer patients

This study was an open-label, 2-arms, monocentric, randomized clinical trial comparing Xonrid®, a topical medical device, versus standard of care (SOC) in preventing and treating acute radiation dermatitis (AR...

Authors: Rossana Ingargiola, Maria Carmen De Santis, Nicola Alessandro Iacovelli, Nadia Facchinetti, Anna Cavallo, Eliana Ivaldi, Michela Dispinzieri, Marzia Franceschini, Carlotta Giandini, Domenico Attilio Romanello, Simona Di Biaso, Michela Sabetti, Laura Locati, Salvatore Alfieri, Paolo Bossi, Mauro Guglielmo…

Low-dose cone-beam CT (LD-CBCT) reconstruction for image-guided radiation therapy (IGRT) by three-dimensional dual-dictionary learning

To develop a low-dose cone beam CT (LD-CBCT) reconstruction method named simultaneous algebraic reconstruction technique and dual-dictionary learning (SART-DDL) joint algorithm for image guided radiation thera...

Authors: Ying Song, Weikang Zhang, Hong Zhang, Qiang Wang, Qing Xiao, Zhibing Li, Xing Wei, Jialu Lai, Xuetao Wang, Wan Li, Quan Zhong, Pan Gong, Renming Zhong and Jun Zhao

Two months of radiation oncology in the heart of Italian “red zone” during COVID-19 pandemic: paving a safe path over thin ice

Coronavirus Disease 2019 (COVID-19) pandemic had an overwhelming impact on healthcare worldwide. Outstandingly, the aftermath on neoplastic patients is still largely unknown, and only isolated cases of COVID-1...

Authors: Michela Buglione, Luigi Spiazzi, Andrea Emanuele Guerini, Fernando Barbera, Nadia Pasinetti, Ludovica Pegurri, Luca Triggiani, Davide Tomasini, Diana Greco, Gianluca Costantino, Alessandra Bragaglio, Nadia Bonometti, Mara Liccioli, Lorella Mascaro, Filippo Alongi and Stefano Maria Magrini

Carbon ion reirradiation compared to intensity-modulated re-radiotherapy for recurrent head and neck cancer (CARE): a randomized controlled trial

Intensity-modulated re-radiotherapy (reIMRT) has been established as a standard local treatment option in patients with non-resectable, recurrent head and neck cancer (rHNC). However, the clinical outcome is u...

Authors: Thomas Held, Kristin Lang, Sebastian Regnery, Katharina Weusthof, Adriane Hommertgen, Cornelia Jäkel, Eric Tonndorf-Martini, Johannes Krisam, Peter Plinkert, Karim Zaoui, Christian Freudlsperger, Julius Moratin, Jürgen Krauss, Semi B. Harrabi, Klaus Herfarth, Jürgen Debus…

Aptamers: a novel targeted theranostic platform for pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is an extremely challenging disease with a high mortality rate and a short overall survival time. The poor prognosis can be explained by aggressive tumor growth, late di...

Authors: Q. Li, S. H. Maier, P. Li, J. Peterhansl, C. Belka, J. Mayerle and U. M. Mahajan

A knowledge-based intensity-modulated radiation therapy treatment planning technique for locally advanced nasopharyngeal carcinoma radiotherapy

To investigate the feasibility of a knowledge-based automated intensity-modulated radiation therapy (IMRT) planning technique for locally advanced nasopharyngeal carcinoma (NPC) radiotherapy.

Authors: Penggang Bai, Xing Weng, Kerun Quan, Jihong Chen, Yitao Dai, Yuanji Xu, Fasheng Lin, Jing Zhong, Tianming Wu and Chuanben Chen

Recent advances in Surface Guided Radiation Therapy

The growing acceptance and recognition of Surface Guided Radiation Therapy (SGRT) as a promising imaging technique has supported its recent spread in a large number of radiation oncology facilities. Although t...

Authors: P. Freislederer, M. Kügele, M. Öllers, A. Swinnen, T.-O. Sauer, C. Bert, D. Giantsoudi, S. Corradini and V. Batista

Factors distinguishing invasive from pre-invasive adenocarcinoma presenting as pure ground glass pulmonary nodules

To investigate predictors of pathological invasiveness and prognosis of lung adenocarcinoma in patients with pure ground-glass nodules (pGGNs).

Authors: Huan-Huan Yang, Yi-Lv Lv, Xing-Hai Fan, Zhi-Yong Ai, Xiu-Chun Xu, Bo Ye and Ding-Zhong Hu

Whole brain radiotherapy (WBRT) for leptomeningeal metastasis from NSCLC in the era of targeted therapy: a retrospective study

Leptomeningeal metastasis (LM) is a rare but detrimental complication in patients with non-small cell lung cancer (NSCLC). Although whole brain radiotherapy (WBRT) is used to eliminating cancer cells or micros...

Authors: Junjie Zhen, Lei Wen, Mingyao Lai, Zhaoming Zhou, Changguo Shan, Shaoqun Li, Tao Lin, Jie Wu, Wensheng Wang, Shaoqiang Xu, Da Liu, Ming Lu, Dan Zhu, Longhua Chen, Linbo Cai and Cheng Zhou

ATM mutations improve radio-sensitivity in wild-type isocitrate dehydrogenase-associated high-grade glioma: retrospective analysis using next-generation sequencing data

To identify the association between somatic ataxia-telangiectasia mutated (ATM) mutations and improved radio-sensitivity, we retrospectively reviewed next-generation sequencing data from patients diagnosed with i...

Authors: Nalee Kim, Se Hoon Kim, Seok-Gu Kang, Ju Hyung Moon, Jaeho Cho, Chang-Ok Suh, Hong In Yoon and Jong Hee Chang

¹⁰⁶Ruthenium eye plaque brachytherapy in the management of medium sized uveal melanoma

To evaluate ¹⁰⁶Ruthenium Brachytherapy in management of medium sized uveal melanoma, with emphasis on 5-year outcome and toxicity.

Authors: Ping Jiang, Konstantine Purtskhvanidze, Gerit Kandzia, Dirk Neumann, Ulf Luetzen, Frank-André Siebert, Johann Roider and Juergen Dunst

Transcriptome network of the papillary thyroid carcinoma radiation marker CLIP2

We present a functional gene association network of the CLIP2 gene, generated by de-novo reconstruction from transcriptomic microarray data. CLIP2 was previously identified as a potential marker for radiation ind...

Authors: Martin Selmansberger, Agata Michna, Herbert Braselmann, Ines Höfig, Kenji Schorpp, Peter Weber, Natasa Anastasov, Horst Zitzelsberger, Julia Hess and Kristian Unger

Convolutional neural networks for head and neck tumor segmentation on 7-channel multiparametric MRI: a leave-one-out analysis

Automatic tumor segmentation based on Convolutional Neural Networks (CNNs) has shown to be a valuable tool in treatment planning and clinical decision making. We investigate the influence of 7 MRI input channe...

Authors: Lars Bielak, Nicole Wiedenmann, Arnie Berlin, Nils Henrik Nicolay, Deepa Darshini Gunashekar, Leonard Hägele, Thomas Lottner, Anca-Ligia Grosu and Michael Bock

Pelvic bone marrow sparing intensity modulated radiotherapy reduces the incidence of the hematologic toxicity of patients with cervical cancer receiving concurrent chemoradiotherapy: a single-center prospective randomized controlled trial

To test the efficacy and feasibility of pelvic bone marrow sparing intensity modulated radiotherapy (PBMS-IMRT) in reducing grade 2 or higher hematological toxicity (HT2+) for patients with cervical cancer tre...

Authors: Jin Huang, Fei Gu, Tianlong Ji, Jing Zhao and Guang Li

The efficacy and dosimetry analysis of CT-guided ¹²⁵I seed implantation assisted with 3D-printing non-co-planar template in locally recurrent rectal cancer

Locally recurrent rectal cancer (LRRC) after surgery or external beam radiotherapy (EBRT) is a serious challenge for which no standard treatment is defined. In the present study, we investigated the feasibilit...

Authors: Lu Wang, Hao Wang, Yuliang Jiang, Zhe Ji, Fuxin Guo, Ping Jiang, Xuemin Li, Yi Chen, Haitao Sun, Jinghong Fan, Weiyan Li, Xu Li and Junjie Wang

Impact of hydrogel peri-rectal spacer insertion on prostate gland intra-fraction motion during 1.5 T MR-guided stereotactic body radiotherapy

The assessment of organ motion is a crucial feature for prostate stereotactic body radiotherapy (SBRT). Rectal spacer may represent a helpful device in order to outdistance rectal wall from clinical target, bu...

Authors: Francesco Cuccia, Rosario Mazzola, Luca Nicosia, Vanessa Figlia, Niccolò Giaj-Levra, Francesco Ricchetti, Michele Rigo, Claudio Vitale, Beatrice Mantoan, Antonio De Simone, Gianluisa Sicignano, Ruggero Ruggieri, Stefano Cavalleri and Filippo Alongi

Late complications of radiosurgery for cerebral arteriovenous malformations: report of 5 cases of chronic encapsulated intracerebral hematomas and review of the literature

Chronic encapsulated intracerebral hematomas (CEIHs) are a rare, late complication of radiosurgery for intracranial AVM. We present 5 cases treated mostly by surgical excision and review the literature.

Authors: Stephanos Finitsis, Valerie Bernier, Isabelle Buccheit, Olivier Klein, Serge Bracard, Francois Zhu, Guillaume Gauchotte and René Anxionnat

Deep learning vs. atlas-based models for fast auto-segmentation of the masticatory muscles on head and neck CT images

Impaired function of masticatory muscles will lead to trismus. Routine delineation of these muscles during planning may improve dose tracking and facilitate dose reduction resulting in decreased radiation-rela...

Authors: Wen Chen, Yimin Li, Brandon A. Dyer, Xue Feng, Shyam Rao, Stanley H. Benedict, Quan Chen and Yi Rong

Novel strategy with the automatic non-coplanar volumetric-modulated arc therapy for angiosarcoma of the scalp

Total scalp irradiation presents technical and dosimetric challenges. While reports suggest that HyperArc, a new stereotactic radiosurgery planning technique applied to non-coplanar volumetric-modulated arc th...

Authors: Shoki Inui, Yoshihiro Ueda, Shingo Ohira, Haruhi Tsuru, Masaru Isono, Masayoshi Miyazaki, Masahiko Koizumi and Teruki Teshima

Radiotherapy for lentigo maligna and lentigo maligna melanoma – a systematic review

Lentigo maligna (LM) is the most common subtype of in situ melanoma und occurs frequently in the sun-exposed head and neck region in elderly patients. The therapeutic “gold standard” is surgical excision, as t...

Authors: Alexandra Hendrickx, Antonio Cozzio, Ludwig Plasswilm and Cédric M. Panje

Stereotactic body radiotherapy for localized prostate cancer – 5-year efficacy results

The use of stereotactic body radiotherapy (SBRT) as the primary treatment modality in clinically localized prostate cancer (PCa) is emerging. The aim of the study was to analyze the long-term results of PCa pa...

Authors: Kristiina Vuolukka, Päivi Auvinen, Erno Tiainen, Jan-Erik Palmgren, Janne Heikkilä, Jan Seppälä, Sirpa Aaltomaa and Vesa Kataja

Voxel-level biological optimisation of prostate IMRT using patient-specific tumour location and clonogen density derived from mpMRI

This study aimed to develop a framework for optimising prostate intensity-modulated radiotherapy (IMRT) based on patient-specific tumour biology, derived from multiparametric MRI (mpMRI). The framework include...

Authors: E. J. Her, A. Haworth, H. M. Reynolds, Y. Sun, A. Kennedy, V. Panettieri, M. Bangert, S. Williams and M. A. Ebert

Exploring MR regression patterns in rectal cancer during neoadjuvant radiochemotherapy with daily T2- and diffusion-weighted MRI

To date, only limited magnetic resonance imaging (MRI) data are available concerning tumor regression during neoadjuvant radiochemotherapy (RCT) of rectal cancer patients, which is a prerequisite for adaptive ...

Authors: T. Bostel, C. Dreher, D. Wollschläger, A. Mayer, F. König, S. Bickelhaupt, H. P. Schlemmer, P. E. Huber, F. Sterzing, P. Bäumer, J. Debus and N. H. Nicolay

Accuracy of real-time respiratory motion tracking and time delay of gating radiotherapy based on optical surface imaging technique

Surface-guided radiation therapy (SGRT) employs a non-invasive real-time optical surface imaging (OSI) technique for patient surface motion monitoring during radiotherapy. The main purpose of this study is to ...

Authors: Li Chen, Sen Bai, Guangjun Li, Zhibin Li, Qing Xiao, Long Bai, Changhu Li, Lixun Xian, Zhenyao Hu, Guyu Dai and Guangyu Wang

The impact of scanning data measurements on the Acuros dose calculation algorithm configuration

Many dose calculation algorithms for radiotherapy planning need to be configured for each clinical beam using pre-defined measurements. An optimization process adjusts the physical parameters able to estimate ...

Authors: A. Fogliata, E. Esposito, L. Paganini, G. Reggiori, S. Tomatis, M. Scorsetti and L. Cozzi

Dosimetric effects of adaptive prostate cancer radiotherapy in an MR-linac workflow

The purpose was to evaluate the dosimetric effects in prostate cancer treatment caused by anatomical changes occurring during the time frame of adaptive replanning in a magnetic resonance linear accelerator (M...

Authors: Annika Mannerberg, Emilia Persson, Joakim Jonsson, Christian Jamtheim Gustafsson, Adalsteinn Gunnlaugsson, Lars E. Olsson and Sofie Ceberg

Chemoradioimmunotherapy of inoperable stage III non-small cell lung cancer: immunological rationale and current clinical trials establishing a novel multimodal strategy

Immune-checkpoint inhibitors (ICI) have dramatically changed the landscape of lung cancer treatment. Preclinical studies investigating combination of ICI with radiation show a synergistic improvement of tumor ...

Authors: Lukas Käsmann, Chukwuka Eze, Julian Taugner, Olarn Roengvoraphoj, Maurice Dantes, Nina-Sophie Schmidt-Hegemann, Sanziana Schiopu, Claus Belka and Farkhad Manapov

Radiotherapy after the easing of public restrictions during COVID-19 epidemic

The daily new confirmed Coronavirus disease 2019 (COVID-19) cases have decreased in some European and Asian countries. Many countries and areas have started to ease public restrictions. Here, we share our expe...

Authors: Weiping Wang, Ke Hu, Jie Qiu and Fuquan Zhang

SARS-CoV-2 prevalence in an asymptomatic cancer cohort - results and consequences for clinical routine

Starting in December 2019, the current pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) confronts the world with an unprecedented challenge. With no vaccine or drug being cur...

Authors: Sebastian Marschner, Stefanie Corradini, Josefine Rauch, Richard Zacharias, Ana Sujic, Julia Mayerle, Raluca Petru, Béatrice Grabein, Oliver T. Keppler, Edwin Boelke, Claus Belka and Maximilian Niyazi

Online adaptive radiotherapy compared to plan selection for rectal cancer: quantifying the benefit

To compare online adaptive radiation therapy (ART) to a clinically implemented plan selection strategy (PS) with respect to dose to the organs at risk (OAR) for rectal cancer.

Authors: R. de Jong, K. F. Crama, J. Visser, N. van Wieringen, J. Wiersma, E. D. Geijsen and A. Bel

Dosimetric comparison between RapidArc and HyperArc techniques in salvage stereotactic body radiation therapy for recurrent nasopharyngeal carcinoma

To evaluate dosimetric differences of salvage irradiations using two commercially available volumetric modulated arc therapy (VMAT) stereotactic body radiation therapy (SBRT) techniques: RapidArc (RA) and Hype...

Authors: Hsiu-Wen Ho, Steve P. Lee, Hisu-Man Lin, Hsiao-Yun Chen, Chun-Chiao Huang, Shih-Chang Wang, Ching-Chieh Yang and Yu-Wei Lin

Magnetic resonance-guided radiation therapy: the beginning of a new era

Authors: Guillaume Landry, Stefanie Corradini and Claus Belka

Study on the ability of 3D gamma analysis and bio-mathematical model in detecting dose changes caused by dose-calculation-grid-size (DCGS)

To explore the efficacy and sensitivity of 3D gamma analysis and bio-mathematical model for cervical cancer in detecting dose changes caused by dose-calculation-grid-size (DCGS).

Authors: Han Bai, Sijin Zhu, Xingrao Wu, Xuhong Liu, Feihu Chen and Jiawen Yan

Can neoadjuvant chemotherapy improve survival in stage T3-4N1 nasopharyngeal carcinoma? A propensity matched analysis

To estimate the efficacy of neoadjuvant chemotherapy (NCT) in stage T3-4N1 nasopharyngeal carcinoma (NPC).

Authors: Lei Wang, Zheng Wu, Dehuan Xie, Shaowen Lv, Liangping Xia and Yong Su

Proton versus photon radiotherapy for primary hepatocellular carcinoma: a propensity-matched analysis

Proton radiotherapy has a dosimetric advantage over photon radiotherapy. Many retrospective studies have shown promising results with proton radiotherapy in treating hepatocellular carcinoma (HCC). However, cl...

Authors: Jen-Yu Cheng, Chieh-Min Liu, Yu-Ming Wang, Hsuan-Chih Hsu, Eng-Yen Huang, Tzu-Ting Huang, Ching-Hsin Lee, Sheng-Ping Hung and Bing-Shen Huang

Oncologic outcomes of pre- versus post-operative radiation in Resectable soft tissue sarcoma: a systematic review and meta-analysis

Postoperative radiation therapy for soft tissue sarcomas demonstrated good local recurrence-free survival rates and survival outcomes. However, the results remained controversial. This study aimed to evaluate ...

Authors: Xinmiao Yang, Lihua Zhang, Xiaojing Yang, Weiwei Yu and Jie Fu

Radiobiological model-based approach to determine the potential of dose-escalated robust intensity-modulated proton radiotherapy in reducing gastrointestinal toxicity in the treatment of locally advanced unresectable pancreatic cancer of the head

The purpose of this study was to determine the potential of escalated dose radiation (EDR) robust intensity-modulated proton radiotherapy (ro-IMPT) in reducing GI toxicity risk in locally advanced unresectable...

Authors: Vijay P. Raturi, Hidehiro Hojo, Kenji Hotta, Hiromi Baba, Ryo Takahashi, Toshiya Rachi, Naoki Nakamura, Sadamoto Zenda, Atsushi Motegi, Hidenobu Tachibana, Takaki Ariji, Kana Motegi, Masaki Nakamura, Masayuki Okumura, Yasuhiro Hirano and Tetsuo Akimoto

Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy

The optimal treatment for lacrimal gland cancer remains unclear. Eye-preserving surgery, as opposed to exenteration, followed by adjuvant radiotherapy (RT), has recently been reported to deliver satisfactory o...

Authors: Yun-Hsuan Lin, Shih-Ming Huang, Wing-Keen Yap, Ju-Wen Yang, Ling Yeung, Din-Li Tsan, Joseph Tung-Chieh Chang and Lung-Chien Chen

Radiotherapy combined with gefitinib for patients with locally advanced non-small cell lung cancer who are unfit for surgery or concurrent chemoradiotherapy: a phase II clinical trial

The objectives of this study were to determine the objective effective response rate, survival, and safety of radiotherapy combined with gefitinib in patients with locally advanced non-small cell lung cancer (...

Authors: Zhixue Fu, Xu Yang, Wenqing Wang, Lei Deng, Tao Zhang, Nan Bi, Xiaozhen Wang, Dongfu Chen, Zongmei Zhou, Luhua Wang and Jun Liang

Radioprotective efficacy of plastic polymer against the toxicogenomic effects of radiopharmaceutical ¹⁸F-FDG on human lymphocytes

Healthcare workers occupationally exposed to ¹⁸F-FDG cannot wear protective equipment, such as lead aprons, since the interaction between high energy radiation (511 keV) and metal increases the dose of radiation ...

Authors: Nilson Benedito Lopes, Igor Vivian Almeida, Pedro Henrique Silvestre Lopes and Veronica Elisa Pimenta Vicentini

Impact of HIV infection on consolidative radiotherapy for non-Hodgkin diffuse large B-cell lymphoma

Even though frequent, it is not known how HIV infection and treatment impact in the consolidation by radiotherapy of non-Hodgkin diffuse large B-cell lymphomas (DBCL). This article aim to assess that differenc...

Authors: Carolina Trindade Mello Medici, Geovanne Pedro Mauro, Lucas Coelho Casimiro and Eduardo Weltman

Clinical implication in the use of the AAA algorithm versus the AXB in nasopharyngeal carcinomas by comparison of TCP and NTCP values

Retrospective analysis of volumetric modulated arc therapy treatment plans to investigate qualitative, possible, clinical consequences of the use of AAA versus AXB in nasopharyngeal cancer (NPC) cases.

Authors: Antonella Bufacchi, Orietta Caspiani, Giulia Rambaldi, Luca Marmiroli, Giuseppe Giovinazzo and Mattia Polsoni