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  1. Para-aortic lymph node (PALN) metastases from primary pelvic malignancies are often treated with resection, but recurrence is common. We report toxicity and oncologic outcomes for patients with PALN metastases...

    Authors: Jacob Hall, Jessica Wilson, John Shumway, Ted K. Yanagihara, Joel Tepper, Benjamin Calvo, Andrew Z. Wang, Kevin Pearlstein, Kyle Wang and Hong Jin Kim
    Citation: Radiation Oncology 2023 18:94
  2. Locally advanced oesophageal cancer can be treated with definitive chemoradiation (dCRT) or with neoadjuvant chemoradiation followed by surgery (nCRT + S), but treatment modality choice is not always clear. Th...

    Authors: Pauliina M. Kitti, Maria Faltinova, Juha Kauppi, Jari Räsänen, Tiina Saarto, Tiina Seppälä and Anu M. Anttonen
    Citation: Radiation Oncology 2023 18:93
  3. Re-irradiation is frequently performed in the era of precision oncology, but previous doses to organs-at-risk (OAR) must be assessed to avoid cumulative overdoses. Stereotactic magnetic resonance-guided online...

    Authors: Sebastian Regnery, Lukas Leiner, Carolin Buchele, Philipp Hoegen, Elisabetta Sandrini, Thomas Held, Maximilian Deng, Tanja Eichkorn, Carolin Rippke, C. Katharina Renkamp, Laila König, Kristin Lang, Sebastian Adeberg, Jürgen Debus, Sebastian Klüter and Juliane Hörner-Rieber
    Citation: Radiation Oncology 2023 18:92
  4. Segmentation of the Gross Tumor Volume (GTV) is a crucial step in the brachytherapy (BT) treatment planning workflow. Currently, radiation oncologists segment the GTV manually, which is time-consuming. The tim...

    Authors: Roque Rodríguez Outeiral, Patrick J. González, Eva E. Schaake, Uulke A. van der Heide and Rita Simões
    Citation: Radiation Oncology 2023 18:91
  5. The incidence of multicentric oral cancer is increasing. However, treatment encounters difficulty if each tumor needs to be treated simultaneously. The objective of this clinical case report is to highlight th...

    Authors: Xuefei Chen, Mitomu Kioi, Yuichiro Hayashi, Toshiyuki Koizumi, Izumi Koike, Shoji Yamanaka, Masaharu Hata and Kenji Mitsudo
    Citation: Radiation Oncology 2023 18:90
  6. In stereotactic radiotherapy, dose is prescribed to an isodose surrounding the planning target volume (PTV). However, the desired dose inhomogeneity inside the PTV leaves the specific dose distribution to the ...

    Authors: Christine Kornhuber, Stephan Ensminger, Patrick Hübsch, Martin Janich, Chris Andre Leucht, Dirk Vordermark and Christian T. Dietzel
    Citation: Radiation Oncology 2023 18:88
  7. The current standard of care for patients with unresectable locally advanced non-small cell lung cancer (NSCLC) is chemoradiotherapy (CRT) combined with durvalumab consolidation therapy. However, radiotherapy ...

    Authors: Mai Sakagami, Haruo Inokuchi, Nobutaka Mukumoto, Hiroshige Itoyama, Nobunari Hamaura, Mutsumi Yamagishi, Naoki Mukumoto, Shogo Matsuda, Daijiro Kabata and Keiko Shibuya
    Citation: Radiation Oncology 2023 18:87
  8. Particle therapy, mainly including carbon-ion radiotherapy (CIRT) and proton beam therapy (PBT), has dose distribution advantages compared to photon radiotherapy. It has been widely reported as a promising tre...

    Authors: Yanliang Chen, Hongtao Luo, Ruifeng Liu, Mingyu Tan, Qian Wang, Xun Wu, Tianqi Du, Zhiqiang Liu, Shilong Sun, Qiuning Zhang and Xiaohu Wang
    Citation: Radiation Oncology 2023 18:86
  9. Lasting local control of brain metastases following stereotactic radiotherapy is becoming increasingly relevant since systemic treatment constantly improves the prognosis of patients with extracranial metastases.

    Authors: Isabella Gruber, Philipp Stark, Karin Weidner, Marius Treutwein and Oliver Koelbl
    Citation: Radiation Oncology 2023 18:85
  10. Reirradiation of prostate cancer (PC) local recurrences represents an emerging challenge for current radiotherapy. In this context, stereotactic body radiation therapy (SBRT) allows the delivery of high doses,...

    Authors: Luca Boldrini, Angela Romano, Giuditta Chiloiro, Stefanie Corradini, Viola De Luca, Valeria Verusio, Andrea D’Aviero, Alessandra Castelluccia, Anna Rita Alitto, Francesco Catucci, Gianmarco Grimaldi, Christian Trapp, Juliane Hörner-Rieber, Domenico Marchesano, Vincenzo Frascino, Gian Carlo Mattiucci…
    Citation: Radiation Oncology 2023 18:84
  11. Chemoradiotherapy complications has always been of great concern to both clinicians and patients during the course of treatment. The purpose of the present study was to examine the effectiveness of oral famoti...

    Authors: Mina Rostami, Omid Yelghi, Zhaleh Karimi Moghaddam, Alireza Zeraatchi, Hamed Rezaeejam and Alireza Sadeghi
    Citation: Radiation Oncology 2023 18:83
  12. The study objective was to validate the relative biological effectiveness (RBE) calculated by the modified microdosimetric kinetic model in RayStation (Ray-MKM) for active-energy scanning carbon-ion radiotherapy.

    Authors: Weiwei Wang, Wei Sun, Hao Shen and Jingfang Zhao
    Citation: Radiation Oncology 2023 18:82
  13. Solid tumors are often riddled with hypoxic areas, which develops as a result of high proliferation. Cancer cells willingly adapt and thrive in hypoxia by activating complex changes which contributes to surviv...

    Authors: Rachel Hanley, Francesca Pagliari, Daniel Garcia-Calderón, Joana Fernandes Guerreiro, Géraldine Genard, Jeannette Jansen, Clelia Nisticò, Maria Grazia Marafioti, Luca Tirinato and Joao Seco
    Citation: Radiation Oncology 2023 18:81
  14. Data on acute toxicities after stereotactic radiotherapy (SRT) for brain metastases, including multiple and large lesions, are lacking. We aimed to evaluate the incidence and nature of toxicities immediately a...

    Authors: Toshiki Ikawa, Naoyuki Kanayama, Hideyuki Arita, Shingo Ohira, Koji Takano, Takero Hirata, Masahiro Morimoto, Teruki Teshima and Koji Konishi
    Citation: Radiation Oncology 2023 18:80
  15. Nearly one fourth of patients with pancreatic ductal adenocarcinoma (PDAC) occur to liver metastasis after surgery, and liver metastasis is a risk factor for prognosis for those patients with surgery therapy. ...

    Authors: Yuzhou Huang, Shurui Zhou, Yanji Luo, Jinmao Zou, Yaqing Li, Shaojie Chen, Ming Gao, Kaihong Huang and Guoda Lian
    Citation: Radiation Oncology 2023 18:79
  16. Long-term follow-up using volumetric measurement could significantly assist in the management of vestibular schwannomas (VS). Manual segmentation of VS from MRI for treatment planning and follow-up assessment ...

    Authors: Hesheng Wang, Tanxia Qu, Kenneth Bernstein, David Barbee and Douglas Kondziolka
    Citation: Radiation Oncology 2023 18:78
  17. This study leverages a large retrospective cohort of head and neck cancer patients in order to develop machine learning models to predict radiation induced hyposalivation from dose-volume histograms of the par...

    Authors: Derek K. Smith, Haley Clark, Allan Hovan and Jonn Wu
    Citation: Radiation Oncology 2023 18:77
  18. Authors: Li Jiang, Jie Zhu, Xue Chen, Yi Wang, Lei Wu, Gang Wan, Yongtao Han, Xuefeng Leng, Lin Peng and Qifeng Wang
    Citation: Radiation Oncology 2023 18:75

    The original article was published in Radiation Oncology 2022 17:218

  19. Patients with locally-advanced non-small-cell lung cancer (LA-NSCLC) are often ineligible for surgery, so that definitive chemoradiotherapy (CRT) represents the treatment of choice. Nevertheless, long-term tum...

    Authors: Sebastian Regnery, Chiara de Colle, Chukwuka Eze, Stefanie Corradini, Christian Thieke, Oliver Sedlaczek, Heinz-Peter Schlemmer, Julien Dinkel, Ferdinand Seith, Annette Kopp-Schneider, Clarissa Gillmann, C. Katharina Renkamp, Guillaume Landry, Daniela Thorwarth, Daniel Zips, Claus Belka…
    Citation: Radiation Oncology 2023 18:74

    The Correction to this article has been published in Radiation Oncology 2023 18:99

  20. In the past, patients with recurrent head and neck cancer (rHNC) who had previously received a high dose of radiation and were unable to undergo surgery were mainly treated with palliative chemotherapy due to ...

    Authors: Yue Li, Yuliang Jiang and Junjie Wang
    Citation: Radiation Oncology 2023 18:73
  21. Surface-guided radiotherapy (SGRT) is used to ensure a reproducible patient set-up and for intra-fraction motion monitoring. The arm position of breast cancer patients is important, since this is related to th...

    Authors: Janita Dekker, Marion Essers, Marcel Verheij, Martijn Kusters and Willy de Kruijf
    Citation: Radiation Oncology 2023 18:72
  22. Small-cell lung cancer (SCLC) is a malignant tumor known for its poor prognosis. In addition to chemotherapy and immunotherapy irradiation plays a big role especially in inoperability. This study evaluated pro...

    Authors: Marie-Theres Kassik, Dirk Vordermark, Christine Kornhuber and Daniel Medenwald
    Citation: Radiation Oncology 2023 18:70
  23. This study explored the application of four-dimensional cone beam computed tomography (4D CBCT) in lung cancer patients, seeking to improve the accuracy of radiotherapy and to establish a uniform protocol for ...

    Authors: Muyasha Abulimiti, Xu Yang, Minghui Li, Fukui Huan, Yanxin Zhang and Liang Jun
    Citation: Radiation Oncology 2023 18:69

    The Correction to this article has been published in Radiation Oncology 2023 18:118

  24. The aim of this study was to evaluate the treatment outcomes and potential dose-response relationship of stereotactic body radiation therapy (SBRT) for pulmonary metastasis of sarcoma.

    Authors: Tae Hoon Lee, Hak Jae Kim, Jin Ho Kim, Mi-Sook Kim, Won Il Jang, Eunji Kim and Kyung Su Kim
    Citation: Radiation Oncology 2023 18:68
  25. To establish a novel model using radiomics analysis of pre-treatment and post-treatment magnetic resonance (MR) images for prediction of progression-free survival in the patients with stage II–IVA nasopharynge...

    Authors: Mi-Xue Sun, Meng-Jing Zhao, Li-Hao Zhao, Hao-Ran Jiang, Yu-Xia Duan and Gang Li
    Citation: Radiation Oncology 2023 18:67
  26. To evaluate the impact of bone marrow (BM) irradiation dose on acute haematologic toxicity (HT) in concurrent chemoradiotherapy for cervical cancer.

    Authors: Min Chen, Dajiang Wang, Zhirong Bao, Zongbi Yi, Zijie Mei, Shaoxing Sun, Qingming Xiang, Chunxu Yang, Hui Yang, Hui Qiu and Conghua Xie
    Citation: Radiation Oncology 2023 18:66
  27. Local recurrence is the most common pattern of failure in head and neck cancer. It can therefore be hypothesised that some of these patients would benefit from an intensified local treatment, such as radiation...

    Authors: Anna Embring, Eva Onjukka, Claes Mercke, Ingmar Lax, Anders Berglund and Signe Friesland
    Citation: Radiation Oncology 2023 18:65
  28. The high susceptibility of the hippocampus region to radiation injury is likely the causal factor of neurocognitive dysfunctions after exposure to ionizing radiation. Repetitive exposures with even low doses h...

    Authors: Hendrik Auerbach, Yvonne Dzierma, Michaela Schürmann, Christian Rübe and Claudia E. Rübe
    Citation: Radiation Oncology 2023 18:64
  29. To analysis the clinical outcomes of concurrent chemoradiotherapy (CCRT) alone based on 10-year results for loco-regionally advanced nasopharyngeal carcinoma (LANPC), so as to provide evidence for individualiz...

    Authors: An-An Xu, Jing-Jing Miao, Lin Wang, An-Chuan Li, Fei Han, Xun-Fan Shao, Zhi-Wen Mo, Shao-Min Huang, Ya-Wei Yuan, Xiao-Wu Deng and Chong Zhao
    Citation: Radiation Oncology 2023 18:63
  30. The management of brain metastases (BM), the major cause of cancer morbidity and mortality, is becoming an emerging area of interest. Surgery, whole brain radiation therapy (WBRT), or stereotactic radiosurgery...

    Authors: Paolo Tini, Francesco Marampon, Martina Giraffa, Samira Bucelli, Maximilian Niyazi, Claus Belka and Giuseppe Minniti
    Citation: Radiation Oncology 2023 18:62
  31. Artificial intelligence-based tools can be leveraged to improve detection and segmentation of brain metastases for stereotactic radiosurgery (SRS). VBrain by Vysioneer Inc. is a deep learning algorithm with re...

    Authors: Jen-Yeu Wang, Vera Qu, Caressa Hui, Navjot Sandhu, Maria G. Mendoza, Neil Panjwani, Yu-Cheng Chang, Chih-Hung Liang, Jen-Tang Lu, Lei Wang, Nataliya Kovalchuk, Michael F. Gensheimer, Scott G. Soltys and Erqi L. Pollom
    Citation: Radiation Oncology 2023 18:61
  32. This study was conducted to evaluate the efficiency and accuracy of the daily patient setup for breast cancer patients by applying surface-guided radiation therapy (SGRT) using the Halcyon system instead of co...

    Authors: Seonghee Kang, Hyeongmin Jin, Ji Hyun Chang, Bum‑Sup Jang, Kyung Hwan Shin, Chang Heon Choi and Jung-in Kim
    Citation: Radiation Oncology 2023 18:60
  33. This study analyzed mortality after radiotherapy for bone metastases (287 courses). Endpoints such as treatment in the last month of life and death within 30, 35 and 40 days from start of radiotherapy were eva...

    Authors: Carsten Nieder, Luka Stanisavljevic, Bård Mannsåker and Ellinor C. Haukland
    Citation: Radiation Oncology 2023 18:59
  34. Hybrid devices that combine radiation therapy and MR-imaging have been introduced in the clinical routine for the treatment of lung cancer. This opened up not only possibilities in terms of accurate tumor trac...

    Authors: Rabea Klaar, Moritz Rabe, Thomas Gaass, Moritz J. Schneider, Ilyes Benlala, Chukwuka Eze, Stefanie Corradini, Claus Belka, Guillaume Landry, Christopher Kurz and Julien Dinkel
    Citation: Radiation Oncology 2023 18:58
  35. Relating dose-volume histogram (DVH) information to patient outcomes is critical for outcomes research in radiation oncology, but this is statistically challenging. We performed this focused review of DVH toxi...

    Authors: Andrew M. McDonald, Craig S. Schneider, John M. Stahl, Robert A. Oster, Richard A. Popple and Charles S. Mayo
    Citation: Radiation Oncology 2023 18:57
  36. This study aimed to compare the adverse reactions of conventional-dose and hypofractionated dose of proton therapy for breast cancer.

    Authors: ZhengShan Hong, ZhaoZhi Yang, Xin Mei, Ping Li, Cihang Bao, Zheng Wang, Xin Cai, Xue Ming, WeiWei Wang, XiaoMao Guo, XiaoLi Yu and Qing Zhang
    Citation: Radiation Oncology 2023 18:56
  37. Despite publication of international guidelines, there are notable controversial points of clinical target volume (CTV) delineation in nasopharyngeal carcinoma (NPC). Recently, scholars proposed a novel way of...

    Authors: Xiaomin Ou, Wenbin Yan, Yangle Huang, Xiayun He, Hongmei Ying, Xueguan Lu, Hui Zhu, Bin Wu, Jiazhou Wang and Chaosu Hu
    Citation: Radiation Oncology 2023 18:55
  38. Utero-vaginal brachytherapy (BT) is an irreplaceable care component for the curative treatment of locally advanced cervix cancer (LACC). Magnetic Resonance Imaging (MRI)-image guided adaptive BT (IGABT) using ...

    Authors: Mark J. Stevens, Florence Ko, Judith Martland, Ryan Brown, Linda Bell, John Atyeo and Jackie Yim
    Citation: Radiation Oncology 2023 18:54
  39. Authors: Anussara Prayongrat, Natchalee Srimaneekarn, Kanokporn Thonglert, Chonlakiet Khorprasert, Napapat Amornwichet, Petch Alisanant, Hiroki Shirato, Keiji Kobashi and Sira Sriswasdi
    Citation: Radiation Oncology 2023 18:53

    The original article was published in Radiation Oncology 2022 17:202

  40. Despite intensive basic scientific, translational, and clinical efforts in the last decades, glioblastoma remains a devastating disease with a highly dismal prognosis. Apart from the implementation of temozolo...

    Authors: Leon Emanuel Schnöller, Daniel Piehlmaier, Peter Weber, Nikko Brix, Daniel Felix Fleischmann, Alexander Edward Nieto, Martin Selmansberger, Theresa Heider, Julia Hess, Maximilian Niyazi, Claus Belka, Kirsten Lauber, Kristian Unger and Michael Orth
    Citation: Radiation Oncology 2023 18:51
  41. During the last decades, radiotherapy (RT) for non-small cell lung cancer (NSCLC) with brain metastases (BM) has been developed. However, the lack of predictive biomarkers for therapeutic responses has limited...

    Authors: Simiao Qiao, Yuying Hao, Linbo Cai, Xiaotong Duan, Lijuan Wang, Aidong Zhou and Xiaoxia Zhu
    Citation: Radiation Oncology 2023 18:50
  42. Stereotactic body radio therapy (SBRT) has emerged as a standard treatment option for nonsurgical candidates with early-stage non-small cell lung cancer (NSCLC). Pathological proof is sometimes difficult to ob...

    Authors: Shaonan Fan, Qi Zhang, Jingyao Chen, Gang Chen, Jiangyi Zhu, Tingting Li, Han Xiao, Shisuo Du, Zhaochong Zeng and Jian He
    Citation: Radiation Oncology 2023 18:49
  43. The incidence of classic radiation-induced liver disease (cRILD) has been significantly reduced. However, non-classic radiation-induced liver disease (ncRILD) remains a major concern following radiotherapy in ...

    Authors: Jian-Xu Li, Rui-Jun Zhang, Mo-Qin Qiu, Liu-Ying Yan, Mei-Ling He, Mei-Ying Long, Jian-Hong Zhong, Hai-Yan Lu, Hong-Mei Zhou, Bang-De Xiang and Shi-Xiong Liang
    Citation: Radiation Oncology 2023 18:48
  44. Lung cancer (LC) is associated with high mortality and poor quality of life (QoL). The disease as well as oncological treatments such as radiation and chemotherapy with adverse effects can impair the QoL of pa...

    Authors: Friedemann Schad, Diana Steinmann, Shiao Li Oei, Anja Thronicke and Christian Grah
    Citation: Radiation Oncology 2023 18:47
  45. This study retrospectively compared the clinical and toxicity outcomes for the cervical cancer of the MRI-guided two adaptive brachytherapy (IGABT) fractions versus one IGABT fraction in one application.

    Authors: Shanshan Song, Dongmei Han, Ning Zhang, Zhuang Mao, Xin Guo and Guanghui Cheng
    Citation: Radiation Oncology 2023 18:46
  46. Authors: Masanori Hirata, Kazuaki Yasui, Naofumi Oota, Hirofumi Ogawa, Tsuyoshi Onoe, Sayo Maki, Yusuke Ito, Kenji Hayashi, Hirofumi Asakura, Shigeyuki Murayama, Koichi Mitsuya, Shoichi Deguchi, Katsumasa Nakamura, Nakamasa Hayashi, Tetsuo Nishimura and Hideyuki Harada
    Citation: Radiation Oncology 2023 18:45

    The original article was published in Radiation Oncology 2022 17:213

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