S3-Leitlinie kolorektales Karzinom. Langversion 2.0 - November 2017 - AWMF-Registernummer: 021/007OL. Stuttgart: Thieme; 2017.
Google Scholar
Peeters KC, Marijnen CA, Nagtegaal ID, et al. The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma. Ann Surg. 2007;246:693–701.
Article
PubMed
Google Scholar
Heald RJ, Moran BJ, Ryall RD, Sexton R, MacFarlane JK. Rectal cancer: the Basingstoke experience of total mesorectal excision, 1978-1997. Arch Surg. 1998;133:894–9.
Article
CAS
PubMed
Google Scholar
Enríquez-Navascués JM, Borda N, Lizerazu A, et al. Patterns of local recurrence in rectal cancer after a multidisciplinary approach. World J Gastroenterol. 2011;17:1674–84.
Article
PubMed
PubMed Central
Google Scholar
Sauer R, Liersch T, Merkel S, et al. Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years. J Clin Oncol. 2012;30:1926–33.
Article
CAS
PubMed
Google Scholar
Cammà C, Giunta M, Fiorica F, Pagliaro L, Craxì A, Cottone M. Preoperative radiotherapy for resectable rectal cancer: a meta-analysis. JAMA. 2000;284:1008–15.
Article
PubMed
Google Scholar
Sauer R, Becker H, Hohenberger W, et al. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med. 2004;351:1731–40.
Article
CAS
PubMed
Google Scholar
Roh MS, Colangelo LH, O'Connell MJ, et al. Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03. J Clin Oncol. 2009;27:5124–30.
Article
PubMed
PubMed Central
Google Scholar
Gerard J-P, Chapet O, Nemoz C, et al. Improved sphincter preservation in low rectal cancer with high-dose preoperative radiotherapy: the Lyon R96-02 randomized trial. J Clin Oncol. 2004;22:2404–9.
Article
PubMed
Google Scholar
Chen C-H, Wei P-L, Hsieh M-C, et al. The outcomes of therapeutic decision in lower 3rd rectal cancer patients. Medicine (Baltimore). 2016;95:e4638.
Article
Google Scholar
Wagman R, Minsky BD, Cohen AM, Guillem JG, Paty PP. Sphincter preservation in rectal cancer with preoperative radiation therapy and coloanal anastomosis: long term follow-up. Int J Radiat Oncol Biol Phys. 1998;42:51–7.
Article
CAS
PubMed
Google Scholar
Deutsche Krebsgesellschaft, Deutsche Krebshilfe (Leitlinienprogramm Onkologie). Interdisziplinäre Leitlinie der Qualität S3 zur Früherkennung, Diagnose und Therapie der verschiedenen Stadien des Prostatakarzinoms, Langversion 5.0 AWMF); 2018. http://www.leitlinienprogramm-onkologie.de/leitlinien/prostatakarzinom/ [accessed last checked: November 3, 2018].
Engstrom PF, Arnoletti JP, Benson AB, et al. NCCN clinical practice guidelines in oncology. Anal carcinoma J Natl Compr Canc Netw. 2010;8:106–20.
Article
PubMed
Google Scholar
X-l D, Tao J, X-g S, et al. Intensity-modulated radiation therapy for advanced cervical cancer: a comparison of dosimetric and clinical outcomes with conventional radiotherapy. Gynecol Oncol. 2012;125:151–7.
Article
Google Scholar
Viani GA, Viana BS, Martin JEC, Rossi BT, Zuliani G, Stefano EJ. Intensity-modulated radiotherapy reduces toxicity with similar biochemical control compared with 3-dimensional conformal radiotherapy for prostate cancer: a randomized clinical trial. Cancer. 2016;122:2004–11.
Article
PubMed
Google Scholar
Kwak Y-K, Lee S-W, Kay CS, Park HH. Intensity-modulated radiotherapy reduces gastrointestinal toxicity in pelvic radiation therapy with moderate dose. PLoS One. 2017;12:e0183339.
Article
CAS
PubMed
PubMed Central
Google Scholar
Arbea L, Ramos LI, Martínez-Monge R, Moreno M, Aristu J. Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications. Radiat Oncol. 2010;5:17.
Article
PubMed
PubMed Central
Google Scholar
Yamashita H, Ishihara S, Nozawa H, et al. Comparison of volumetric-modulated arc therapy using simultaneous integrated boosts (SIB-VMAT) of 45 Gy/55 Gy in 25 fractions with conventional radiotherapy in preoperative chemoradiation for rectal cancers: a propensity score case-matched analysis. Radiat Oncol. 2017;12:156.
Article
CAS
PubMed
PubMed Central
Google Scholar
Huang C-M, Huang M-Y, Tsai H-L, et al. A retrospective comparison of outcome and toxicity of preoperative image-guided intensity-modulated radiotherapy versus conventional pelvic radiotherapy for locally advanced rectal carcinoma. J Radiat Res. 2017;58:247–59.
Article
CAS
PubMed
Google Scholar
Simson DK, Mitra S, Ahlawat P, et al. Prospective study of neoadjuvant chemoradiotherapy using intensity-modulated radiotherapy and 5 fluorouracil for locally advanced rectal cancer - toxicities and response assessment. Cancer Manag Res. 2018;10:519–26.
Article
PubMed
PubMed Central
Google Scholar
Benson AB, Venook AP, Al-Hawary MM, et al. Rectal Cancer, version 2.2018, NCCN clinical practice guidelines in oncology. J Natl Compr Cancer Netw. 2018;16:874–901.
Article
Google Scholar
Emmertsen KJ, Laurberg S. Bowel dysfunction after treatment for rectal cancer. Acta Oncol. 2008;47:994–1003.
Article
PubMed
Google Scholar
Lundby L, Jensen VJ, Overgaard J, Laurberg S. Long-term colorectal function after postoperative radiotherapy for colorectal cancer. Lancet. 1997;350:564.
Article
CAS
PubMed
Google Scholar
Pollack J, Holm T, Cedermark B, et al. Late adverse effects of short-course preoperative radiotherapy in rectal cancer. Br J Surg. 2006;93:1519–25.
Article
CAS
PubMed
Google Scholar
Birgisson H, Påhlman L, Gunnarsson U, Glimelius B. Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish rectal Cancer trial. J Clin Oncol. 2005;23:8697–705.
Article
PubMed
Google Scholar
Peeters KCMJ, van de Velde CJH, Leer JWH, et al. Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients--a Dutch colorectal cancer group study. J Clin Oncol. 2005;23:6199–206.
Article
CAS
PubMed
Google Scholar
Ammann K, Kirchmayr W, Klaus A, et al. Impact of neoadjuvant chemoradiation on anal sphincter function in patients with carcinoma of the midrectum and low rectum. Arch Surg. 2003;138:257–61.
Article
PubMed
Google Scholar
Alsadius D, Hedelin M, Lundstedt D, Pettersson N, Wilderäng U, Steineck G. Mean absorbed dose to the anal-sphincter region and fecal leakage among irradiated prostate cancer survivors. Int J Radiat Oncol Biol Phys. 2012;84:e181–5.
Article
PubMed
Google Scholar
Arias F, Eito C, Asín G, et al. Fecal incontinence and radiation dose on anal sphincter in patients with locally advanced rectal cancer (LARC) treated with preoperative chemoradiotherapy: a retrospective, single-institutional study. Clin Transl Oncol. 2017;19:969–75.
Article
CAS
PubMed
Google Scholar
Wang D, Zhang Q, Eisenberg BL, et al. Significant reduction of late toxicities in patients with extremity sarcoma treated with image-guided radiation therapy to a reduced target volume: results of radiation therapy oncology group RTOG-0630 trial. J Clin Oncol. 2015;33:2231–8.
Article
PubMed
PubMed Central
Google Scholar
Marks LB, Yorke ED, Jackson A, et al. Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys. 2010;76:S10–9.
Article
PubMed
PubMed Central
Google Scholar
Myerson RJ, Garofalo MC, El Naqa I, et al. Elective clinical target volumes for conformal therapy in anorectal cancer: a radiation therapy oncology group consensus panel contouring atlas. Int J Radiat Oncol Biol Phys. 2009;74:824–30.
Article
PubMed
Google Scholar
Chen Y-J, Chen MB, Liu AJ, Sanchez J, Tsai P, Liu A. Dosimetric coverage of the external anal sphincter by 3-dimensional conformal fields in rectal cancer patients receiving neoadjuvant chemoradiation: implications for the concept of sphincter-preserving radiation therapy. Biomed Res Int. 2014;2014:578243.
PubMed
PubMed Central
Google Scholar
Buettner F, Gulliford SL, Webb S, Sydes MR, Dearnaley DP, Partridge M. The dose-response of the anal sphincter region--an analysis of data from the MRC RT01 trial. Radiother Oncol. 2012;103:347–52.
Article
PubMed
Google Scholar
Fuller CD, Nijkamp J, Duppen JC, et al. Prospective randomized double-blind pilot study of site-specific consensus atlas implementation for rectal cancer target volume delineation in the cooperative group setting. Int J Radiat Oncol Biol Phys. 2011;79:481–9.
Article
PubMed
Google Scholar
Nijkamp J, de Haas-Kock DF, Beukema JC, et al. Target volume delineation variation in radiotherapy for early stage rectal cancer in the Netherlands. Radiother Oncol. 2012;102:14–21.
Article
PubMed
Google Scholar
Joye I, Macq G, Vaes E, et al. Do refined consensus guidelines improve the uniformity of clinical target volume delineation for rectal cancer? Results of a national review project. Radiother Oncol. 2016;120:202–6.
Article
PubMed
Google Scholar
Syk E, Torkzad MR, Blomqvist L, Nilsson PJ, Glimelius B. Local recurrence in rectal cancer: anatomic localization and effect on radiation target. Int J Radiat Oncol Biol Phys. 2008;72:658–64.
Article
PubMed
Google Scholar
Kusters M, Marijnen CAM, van de Velde CJH, et al. Patterns of local recurrence in rectal cancer; a study of the Dutch TME trial. Eur J Surg Oncol. 2010;36:470–6.
Article
CAS
PubMed
Google Scholar
Valentini V, Gambacorta MA, Barbaro B, et al. International consensus guidelines on clinical target volume delineation in rectal cancer. Radiother Oncol. 2016;120:195–201.
Article
PubMed
Google Scholar
Gunther JR, Chadha AS, Shin US, et al. Preoperative radiation dose escalation for rectal cancer using a concomitant boost strategy improves tumor downstaging without increasing toxicity: a matched-pair analysis. Adv Radiat Oncol. 2017;2:455–64.
Article
PubMed
PubMed Central
Google Scholar