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Table 3 Mean V5–V45 of different anal sphincters in rectal cancer patients treated with IMRT or 3D-radiation technique

From: Impact of VMAT-IMRT compared to 3D conformal radiotherapy on anal sphincter dose distribution in neoadjuvant chemoradiation of rectal cancer

  V5 V10 V20 V30 V40 V45
Anal Sphincter (%)
 IMRT 98,7 91,0 80,1 76,6 74,4 73,4
 3D 99,7 98,8 96,5 95,1 90,9 58,0
 p-value 0,258 0,008 0,004 0,001 0,007 0,003
Internal Anal Sphincter (%)
 IMRT 98,0 87,1 73,6 69,4 66,4 65,3
 3D 100,0 100,0 97,5 94,6 88,9 51,2
 p-value 0,500 0,022 0,001 0,002 0,003 0,007
External Anal Sphincter (%)
 IMRT 98,1 87,2 73,0 68,8 66,0 64,8
 3D 99,4 97,3 91,6 88,9 79,4 38,3
 p-value 0,258 0,010 0,004 0,005 0,007 0,001
Levator Ani (%)
 IMRT 100,0 99,9 98,6 91,7 97,5 97,3
 3D 100,0 99,8 99,3 99,3 98,3 65,9
 p-value 1,000 0,258 0,129 0,062 0,067 0,000
  1. IMRT Intensity modulated radiation therapy, 3D 3D-conformal radiation therapy
  2. boldfaced p-values are statistically significant