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  1. The quality of the interdisciplinary interface in oncological treatment between surgery, pathology and radiotherapy is mainly dependent on reliable anatomical three-dimensional (3D) allocation of specimen and ...

    Authors: Harald Essig, Majeed Rana, Andreas Meyer, André M Eckardt, Horst Kokemueller, Constantin von See, Daniel Lindhorst, Frank Tavassol, Martin Ruecker and Nils-Claudius Gellrich
    Citation: Radiation Oncology 2011 6:159
  2. To assess the accuracy of patient repositioning and clinical outcomes of frameless stereotactic radiosurgery (SRS) for brain metastases using a stereotactic mask fixation system.

    Authors: Giuseppe Minniti, Claudia Scaringi, Enrico Clarke, Maurizio Valeriani, Mattia Osti and Riccardo Maurizi Enrici
    Citation: Radiation Oncology 2011 6:158
  3. Stereotactic radiosurgery/radiotherapy procedures are known to deliver a very high dose per fraction, and thus, the corresponding peripheral dose could be a limiting factor for the long term surviving patients...

    Authors: Vassiliki Vlachopoulou, Christos Antypas, Harry Delis, Argyrios Tzouras, Nikolaos Salvaras, Dimitrios Kardamakis and George Panayiotakis
    Citation: Radiation Oncology 2011 6:157
  4. Radiation therapy is routinely prescribed for high-grade malignant gliomas. However, the efficacy of this therapeutic modality is often limited by the occurrence of radioresistance, reflected as a diminished s...

    Authors: Carlos A Fedrigo, Ivana Grivicich, Daniel P Schunemann, Ivan M Chemale, Daiane dos Santos, Thais Jacovas, Patryck S Boschetti, Geraldo P Jotz, Aroldo Braga Filho and Adriana B da Rocha
    Citation: Radiation Oncology 2011 6:156
  5. To report the clinical outcome after a Single Shot 3D-CRT PBI (SSPBI) in breast cancer patients after conservative surgery (ClinicalTrials.gov Identifier: NCT01316328).

    Authors: Paola Pinnarò, Stefano Arcangeli, Carolina Giordano, Giorgio Arcangeli, Fabrizio Ambesi Impiombato, Valentina Pinzi, Giuseppe Iaccarino, Antonella Soriani, Valeria Landoni and Lidia Strigari
    Citation: Radiation Oncology 2011 6:155
  6. Although 3D-conformal accelerated partial breast irradiation (APBI) is widely used, several questions still remain such as what are the optimal treatment planning modalities. Indeed, some patients may have an ...

    Authors: Mohamed El Nemr, Steve Heymann, Rodolfe Verstraet, Bruno Biron, Fares Azoury, Hugo Marsiglia and Céline Bourgier
    Citation: Radiation Oncology 2011 6:154
  7. In order to define new prognostic subgroups in patients with glioblastoma a miRNA screen (> 1000 miRNAs) from paraffin tissues followed by a bio-mathematical analysis was performed.

    Authors: Maximilian Niyazi, Franz Zehentmayr, Olivier M Niemöller, Sabina Eigenbrod, Hans Kretzschmar, Klaus Schulze-Osthoff, Jörg-Christian Tonn, Mike Atkinson, Simone Mörtl and Claus Belka
    Citation: Radiation Oncology 2011 6:153
  8. Frequently, three-dimensional (3D) conformal beams are used in lung cancer stereotactic body radiotherapy (SBRT). Recently, volumetric modulated arc therapy (VMAT) was introduced as a new treatment modality. V...

    Authors: Geoffrey G Zhang, Lichung Ku, Thomas J Dilling, Craig W Stevens, Ray R Zhang, Weiqi Li and Vladimir Feygelman
    Citation: Radiation Oncology 2011 6:152
  9. To evaluate the cardiac toxicity of radiotherapy (RT) in breast cancer (BC) patients employing myocardial perfusion imaging (MPI) with Tc-99 m Tetrofosmin - single photon emission computer tomography (T-SPECT).

    Authors: Chrissa Sioka, Thomas Exarchopoulos, Ifigenia Tasiou, Eftychia Tzima, Nikolaos Fotou, Antonio Capizzello, Vasilios Ragos, Periklis Tsekeris and Andreas Fotopoulos
    Citation: Radiation Oncology 2011 6:151
  10. To evaluate prognostic factors in salvage radiotherapy (RT) for patients with pre-RT prostate-specific antigen (PSA) < 1.0 ng/ml.

    Authors: Rei Umezawa, Hisanori Ariga, Yoshihiro Ogawa, Keiichi Jingu, Haruo Matsushita, Ken Takeda, Keisuke Fujimoto, Toru Sakayauchi, Toshiyuki Sugawara, Masaki Kubozono, Kakutaro Narazaki, Eiji Shimizu, Yoshihiro Takai and Shogo Yamada
    Citation: Radiation Oncology 2011 6:150
  11. To investigate toxicity and efficacy in high-risk malignant salivary gland tumors (MSGT) of the head and neck. Local control in R2-resected adenoid cystic carcinoma was already improved with a combination of I...

    Authors: Alexandra D Jensen, Anna V Nikoghosyan, Swantje Ecker, Malte Ellerbrock, Jürgen Debus, Klaus K Herfarth and Marc W Münter
    Citation: Radiation Oncology 2011 6:149
  12. Vaults are evolutionary highly conserved ribonucleoproteins particles with a hollow barrel-like structure. The main component of vaults represents the 110 kDa major vault protein (MVP), whereas two minor vault...

    Authors: Pedro C Lara, Martin Pruschy, Martina Zimmermann and Luis Alberto Henríquez-Hernández
    Citation: Radiation Oncology 2011 6:148
  13. To compare volumetric-modulated arc therapy plans with conventional radiation therapy (3D-CRT) plans in pancreatic and bile duct cancers, especially for bilateral kidney preservation.

    Authors: Sabine Vieillot, David Azria, Olivier Riou, Carmen Llacer Moscardo, Jean-Bernard Dubois, Norbert Aillères and Pascal Fenoglietto
    Citation: Radiation Oncology 2011 6:147
  14. The retroperitoneal margin is a common site of positive surgical margins in patients with resectable pancreatic cancer. Preoperative margin-intensive therapy (MIT) involves delivery of a single high dose of ab...

    Authors: John H Heinzerling, Ross Bland, John C Mansour, Roderich E Schwarz, Ezequiel Ramirez, Chuxiong Ding, Ramzi Abdulrahman, Thomas P Boike, Timothy Solberg, Robert D Timmerman and Jeffrey J Meyer
    Citation: Radiation Oncology 2011 6:146
  15. Image-guided radiotherapy (IGRT) increases the accuracy of treatment delivery through daily target localisation. We report on toxicity symptoms experienced during radiotherapy treatment, with and without IGRT ...

    Authors: Suki Gill, Jessica Thomas, Chris Fox, Tomas Kron, Aldo Rolfo, Mary Leahy, Sarat Chander, Scott Williams, Keen Hun Tai, Gillian M Duchesne and Farshad Foroudi
    Citation: Radiation Oncology 2011 6:145
  16. Prostate cancer (PrCa) displays resistance to radiotherapy (RT) and requires radiotherapy dose escalation which is associated with greater toxicity. This highlights a need to develop radiation sensitizers to i...

    Authors: Ayesha Rashid, Caiqiong Liu, Toran Sanli, Evangelia Tsiani, Gurmit Singh, Robert G Bristow, Ian Dayes, Himu Lukka, James Wright and Theodoros Tsakiridis
    Citation: Radiation Oncology 2011 6:144
  17. Spinal cord stimulators (SCS) are a well-recognised treatment modality in the management of a number of chronic neuropathic pain conditions, particularly failed back syndrome and radiculopathies. The implantab...

    Authors: Lorraine Walsh, Daipayan Guha, Thomas G Purdie, Philippe Bedard, Alexandra Easson, Fei-Fei Liu and Mojgan Hodaie
    Citation: Radiation Oncology 2011 6:143
  18. To evaluate the daily total error shift patterns on post-prostatectomy patients undergoing image guided radiotherapy (IGRT) with a diagnostic quality computer tomography (CT) on rails system.

    Authors: Ronaldo Cavalieri, Hiram A Gay, Jingxia Liu, Maria C Ferreira, Helvecio C Mota, Claudio H Sibata and Ron R Allison
    Citation: Radiation Oncology 2011 6:142
  19. To analyze the differences between the intensity-modulated radiotherapy (IMRT), single/partial-arc volumetric modulated arc therapy (SA/PA-VMAT) techniques in treatment planning for locally advanced lung cancer.

    Authors: Xiaoqin Jiang, Tao Li, Yongmei Liu, Lin Zhou, Yong Xu, Xiaojuan Zhou and Youling Gong
    Citation: Radiation Oncology 2011 6:140
  20. Laser acceleration of protons and heavy ions may in the future be used in radiation therapy. Laser-driven particle beams are pulsed and ultra high dose rates of >109 Gy s-1may be achieved. Here we compare the rad...

    Authors: Susanne Auer, Volker Hable, Christoph Greubel, Guido A Drexler, Thomas E Schmid, Claus Belka, Günther Dollinger and Anna A Friedl
    Citation: Radiation Oncology 2011 6:139
  21. Chest wall injury after stereotactic radiotherapy (SRT) for primary lung cancer has recently been reported. However, its detailed imaging findings are not clarified. So this study aimed to fully characterize t...

    Authors: Atsushi Nambu, Hiroshi Onishi, Shinichi Aoki, Tsuyota Koshiishi, Kengo Kuriyama, Takafumi Komiyama, Kan Marino, Masayuki Araya, Ryo Saito, Lichto Tominaga, Yoshiyasu Maehata, Eiichi Sawada and Tsutomu Araki
    Citation: Radiation Oncology 2011 6:137
  22. Oral cavity cancers (ORC) are the most common cancers, and standard treatment is radical surgery with postoperative radiotherapy. However, locoregional failure remains a major problem, indicating radioresistan...

    Authors: Chien-Yu Lin, Ting-Yang Lin, Hung-Ming Wang, Shiang-Fu Huang, Kang-Hsing Fan, Chun-Ta Liao, I-How Chen, Li-Yu Lee, Yen-Liang Li, Yin-Ju Chen, Ann-Joy Cheng and Joseph T Chang
    Citation: Radiation Oncology 2011 6:136
  23. We aimed to assess outcomes of patients with anal cancer who underwent intensity-modulated radiotherapy (IMRT) and received less than 1.80 Gy/day.

    Authors: Jason A Call, Michael G Haddock, J Fernando Quevedo, David W Larson and Robert C Miller
    Citation: Radiation Oncology 2011 6:134
  24. Mitochondrial DNA (mtDNA) alterations, including mtDNA copy number and mtDNA 4977 bp common deletion (CD), are key indicators of irradiation-induced damage. The relationship between total body irradiation (TBI...

    Authors: Quan Wen, Yide Hu, Fuyun Ji and Guisheng Qian
    Citation: Radiation Oncology 2011 6:133
  25. Sublethal photon irradiation was recently suspected to increase tumor cell motility and promote locoregional recurrence of disease. This study was set up to describe mechanisms underlying increased glioma cell...

    Authors: Stefan Rieken, Daniel Habermehl, Angela Mohr, Lena Wuerth, Katja Lindel, Klaus Weber, Jürgen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2011 6:132
  26. Although the nodal ratio (NR) has been recognized as a prognostic factor in breast cancer, its clinical implication in patients with 1-3 positive nodes (N1) remains unclear. Here, we evaluated the prognostic v...

    Authors: Tae Jin Han, Eun Young Kang, Wan Jeon, Sung-Won Kim, Jee Hyun Kim, Yu Jung Kim, So Yeon Park, Jae Sung Kim and In Ah Kim
    Citation: Radiation Oncology 2011 6:131
  27. The aim was to determine the incidence of seed migration not only to the chest, but also to the abdomen and pelvis after transperineal interstitial prostate brachytherapy with loose 125I seeds.

    Authors: Akitomo Sugawara, Jun Nakashima, Etsuo Kunieda, Hirohiko Nagata, Ryuichi Mizuno, Satoshi Seki, Yutaka Shiraishi, Ryuichi Kouta, Mototsugu Oya and Naoyuki Shigematsu
    Citation: Radiation Oncology 2011 6:130
  28. A new-generation low-energy linear accelerator (UNIQUE) was introduced in the clinical arena during 2009 by Varian Medical Systems. The world's first UNIQUE was installed at Oncology Institute of Southern Swit...

    Authors: Alessandro Clivio, Giorgia Nicolini, Eugenio Vanetti, Antonella Fogliata and Luca Cozzi
    Citation: Radiation Oncology 2011 6:129
  29. Temporal lobe necrosis (TLN) is the most debilitating late-stage complication after radiation therapy in patients with nasopharyngeal cancer (NPC). The bilateral temporal lobes are inevitably encompassed in th...

    Authors: Jing Chen, Meera Dassarath, Zhongyuan Yin, Hongli Liu, Kunyu Yang and Gang Wu
    Citation: Radiation Oncology 2011 6:128
  30. Postoperative chemoradiation as per Intergroup-0116 trial ("Macdonald regimen") is considered standard for completely resected high risk gastric cancer. However, many concerns remain with regards to the toxici...

    Authors: Yulia Kundel, Ofer Purim, Efraim Idelevich, Konstantin Lavrenkov, Sofia Man, Svetlana Kovel, Natalia Karminsky, Raphael M Pfeffer, Bella Nisenbaum, Eyal Fenig, Aaron Sulkes and Baruch Brenner
    Citation: Radiation Oncology 2011 6:127
  31. The role of adjuvant chemoradiation therapy for ampullary carcinoma is unknown. Previous literature suggests that certain populations with high risk factors for recurrence may benefit from adjuvant chemoradiat...

    Authors: Amol K Narang, Robert C Miller, Charles C Hsu, Sumita Bhatia, Timothy M Pawlik, Dan Laheru, Ralph H Hruban, Jessica Zhou, Jordan M Winter, Michael G Haddock, John H Donohue, Richard D Schulick, Christopher L Wolfgang, John L Cameron and Joseph M Herman
    Citation: Radiation Oncology 2011 6:126
  32. The aim of the present study was to evaluate the recovery potential of the parotid glands after using either 3D-conformal-radiotherapy (3D-CRT) or intensity-modulated radiotherapy (IMRT) by sparing one single ...

    Authors: Jeremias Hey, Juergen Setz, Reinhard Gerlach, Martin Janich, Guido Hildebrandt, Dirk Vordermark, Christian R Gernhardt and Thomas Kuhnt
    Citation: Radiation Oncology 2011 6:125
  33. To explore possible improvement in the treatment of locally advanced pancreatic carcinoma (LAPC) we performed a randomized, non-comparative phase II study evaluating docetaxel - plus either daily continuous 5 ...

    Authors: Lucie Oberic, Frédéric Viret, Charlotte Baey, Marc Ychou, Jaafar Bennouna, Antoine Adenis, Didier Peiffert, Françoise Mornex, Jean-Pierre Pignon, Patrice Celier, Jocelyne Berille and Michel Ducreux
    Citation: Radiation Oncology 2011 6:124
  34. Several investigations have recently suggested the existence of a correlation between the dose received by the penile bulb (PB) and the risk of erectile dysfunction (ED) after radical radiotherapy for clinical...

    Authors: Lucia Perna, Cesare Cozzarini, Eleonora Maggiulli, Gianni Fellin, Tiziana Rancati, Riccardo Valdagni, Vittorio Vavassori, Sergio Villa and Claudio Fiorino
    Citation: Radiation Oncology 2011 6:123
  35. To report our experience on disease control and functional outcome using three modern combined-modality approaches for definitive radiochemotherapy of locally advanced SCCHN with modern radiotherapy techniques...

    Authors: Alexandra D Jensen, Jürgen Krauss, Wilko Weichert, Zazie P Bergmann, Kolja Freier, Jürgen Debus and Marc W Münter
    Citation: Radiation Oncology 2011 6:122
  36. Early and accurate prediction of response to cancer treatment through imaging criteria is particularly important in rapidly progressive malignancies such as Glioblastoma Multiforme (GBM). We sought to assess t...

    Authors: Adam Gladwish, Eng-Siew Koh, Jeremy Hoisak, Gina Lockwood, Barbara-Ann Millar, Warren Mason, Eugene Yu, Normand J Laperriere and Cynthia Ménard
    Citation: Radiation Oncology 2011 6:121
  37. Former prospective analyses revealed gross tumor volume (GTV) as the most reliable parameter to statistically significantly predict disease control in head neck cancer (HNC) patients treated with definitive in...

    Authors: Gabriela Studer, Tamara Rordorf and Christoph Glanzmann
    Citation: Radiation Oncology 2011 6:120
  38. The pan-HDAC inhibitor (HDACI) suberoylanilide hydroxamic acid (SAHA) has previously shown to be a radio-sensitizer to conventional photon radiotherapy (XRT) in pediatric sarcoma cell lines. Here, we investiga...

    Authors: Susanne Oertel, Markus Thiemann, Karsten Richter, Klaus-J Weber, Peter E Huber, Ramon Lopez Perez, Stephan Brons, Marc Bischof, Andreas E Kulozik, Volker Ehemann, Jürgen Debus and Claudia Blattmann
    Citation: Radiation Oncology 2011 6:119
  39. As part of French residents' radiotherapy training, delineation workstations were available at a national teaching course. We report a prospective comparative study of a non small cell lung cancer (NSCLC) case...

    Authors: Sylvain Dewas, Jean-Emmanuel Bibault, Pierre Blanchard, Claire Vautravers-Dewas, Yoann Pointreau, Fabrice Denis, Michel Brauner and Philippe Giraud
    Citation: Radiation Oncology 2011 6:118
  40. We analyzed our long-term experience with fractionated stereotactic radiotherapy (FSRT) in patients with meningioma of the optic nerve sheath (ONSM).

    Authors: Sebastian Adeberg, Thomas Welzel, Stefan Rieken, Jürgen Debus and Stephanie E Combs
    Citation: Radiation Oncology 2011 6:117
  41. Chordoma, a rare cancer, is usually treated with surgery and/or radiation. However, very limited characterizations of chordoma cells are available due to a minimal availability (only two lines validated by now...

    Authors: Takamitsu A Kato, Akihisa Tsuda, Mitsuru Uesaka, Akira Fujimori, Tadashi Kamada, Hirohiko Tsujii and Ryuichi Okayasu
    Citation: Radiation Oncology 2011 6:116
  42. A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate de...

    Authors: Stephanie E Combs, Stefan Rieken, Wolfgang Wick, Amir Abdollahi, Andreas von Deimling, Jürgen Debus and Christian Hartmann
    Citation: Radiation Oncology 2011 6:115
  43. KRAS mutations may predict poor response to radiotherapy. Downstream events from KRAS, such as activation of BRAF, AKT and ERK, may also confer prognostic information but have not been tested in rectal cancer (RC...

    Authors: Janine M Davies, Dimitri Trembath, Allison M Deal, William K Funkhouser, Benjamin F Calvo, Timothy Finnegan, Karen E Weck, Joel E Tepper and Bert H O'Neil
    Citation: Radiation Oncology 2011 6:114
  44. To test feasibility and safety of clinical usage of Flattening Filter Free (FFF) beams for delivering ablative stereotactic body radiation therapy (SBRT) doses to various tumor sites, by means of Varian TrueBe...

    Authors: Marta Scorsetti, Filippo Alongi, Simona Castiglioni, Alessandro Clivio, Antonella Fogliata, Francesca Lobefalo, Pietro Mancosu, Pierina Navarria, Valentina Palumbo, Chiara Pellegrini, Sara Pentimalli, Giacomo Reggiori, Anna M Ascolese, Antonella Roggio, Stefano Arcangeli, Angelo Tozzi…
    Citation: Radiation Oncology 2011 6:113
  45. Increasing clinical data supports a low α/β ratio for prostate adenocarcinoma, potentially lower than that of surrounding normal tissues. A hypofractionated, weekly radiation therapy (RT) schedule should resul...

    Authors: Cathy Menkarios, Éric Vigneault, Nicolas Brochet, David HA Nguyen, Jean-Paul Bahary, Marjory Jolicoeur, Marie-Claude Beauchemin, Hugo Villeneuve, Thu Van Nguyen, Bernard Fortin and Carole Lambert
    Citation: Radiation Oncology 2011 6:112
  46. Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas), the combination of this agent with c...

    Authors: Matthias Bache, Martin P Zschornak, Sarina Passin, Jacqueline Keßler, Henri Wichmann, Matthias Kappler, Reinhard Paschke, Goran N Kaluđerović, Harish Kommera, Helge Taubert and Dirk Vordermark
    Citation: Radiation Oncology 2011 6:111
  47. Prostate bed (PB) contouring is time consuming and associated with inter-observer variability. We evaluated an automated atlas-based segmentation (AABS) engine in its potential to reduce contouring time and in...

    Authors: Jeremiah Hwee, Alexander V Louie, Stewart Gaede, Glenn Bauman, David D'Souza, Tracy Sexton, Michael Lock, Belal Ahmad and George Rodrigues
    Citation: Radiation Oncology 2011 6:110

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