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  1. This study evaluated the effectiveness and safety of preoperative chemoradiotherapy with capecitabine in patients with locally advanced resectable rectal cancer. This report summarizes the results of the phase...

    Authors: Vaneja Velenik, Irena Oblak and Franc Anderluh
    Citation: Radiation Oncology 2010 5:88
    Content type: Research Published on:

  3. The aim was to identify preimplant factors affecting postimplant prostate volume and the increase in prostate volume after transperineal interstitial prostate brachytherapy with 125I free seeds.

    Authors: Akitomo Sugawara, Jun Nakashima, Etsuo Kunieda, Hirohiko Nagata, Hirotaka Asakura, Mototsugu Oya and Naoyuki Shigematsu
    Citation: Radiation Oncology 2010 5:86
    Content type: Research Published on:

  4. DNA-damage assays, quantifying the initial number of DNA double-strand breaks induced by radiation, have been proposed as a predictive test for radiation-induced toxicity. Determination of radiation-induced ap...

    Authors: Beatriz Pinar, Luis Alberto Henríquez-Hernández, Pedro C Lara, Elisa Bordon, Carlos Rodriguez-Gallego, Marta Lloret, Maria Isabel Nuñez and Mariano Ruiz De Almodovar
    Citation: Radiation Oncology 2010 5:85
    Content type: Research Published on:

  5. This is a prospective comparison of weekly cisplatin to weekly paclitaxel as concurrent chemotherapy with standard radiotherapy for locally advanced cervical carcinoma.

    Authors: Fady B Geara, Ali Shamseddine, Ali Khalil, Mirna Abboud, Maya Charafeddine and Muhieddine Seoud
    Citation: Radiation Oncology 2010 5:84
    Content type: Study protocol Published on:

  6. Radiotherapy for retroperitoneal sarcomas remains controversial and a technical challenge considering the threshold of contiguous critical organs tolerance. We performed consecutive RapidArc dosimetric plans i...

    Authors: Carmen Llacer-Moscardo, François Quenet, David Azria and Pascal Fenoglietto
    Citation: Radiation Oncology 2010 5:83
    Content type: Research Published on:

  7. Osteopontin (OPN) is a secreted glycophosphoprotein that is overexpressed in various tumors, and high levels of OPN have been associated with poor prognosis of cancer patients. In patients with head and neck c...

    Authors: Antje Hahnel, Henri Wichmann, Matthias Kappler, Matthias Kotzsch, Dirk Vordermark, Helge Taubert and Matthias Bache
    Citation: Radiation Oncology 2010 5:82
    Content type: Research Published on:

  8. The treatment schedules for stereotactic body radiotherapy (SBRT) for lung cancer vary from institution to institution. Several reports have indicated that stage IB patients had worse outcomes than stage IA pa...

    Authors: Fumiya Baba, Yuta Shibamoto, Hiroyuki Ogino, Rumi Murata, Chikao Sugie, Hiromitsu Iwata, Shinya Otsuka, Katsura Kosaki, Aiko Nagai, Taro Murai and Akifumi Miyakawa
    Citation: Radiation Oncology 2010 5:81
    Content type: Research Published on:

  9. The purpose of this study was to determine the expected time to prostate specific antigen (PSA) normalization with or without neoadjuvant androgen deprivation (NAAD) therapy after treatment with intensity modu...

    Authors: Matthew D Schmitz, Gilbert DA Padula, Patrick Y Chun and Alan T Davis
    Citation: Radiation Oncology 2010 5:80
    Content type: Research Published on:

  10. Most treatment failure of buccal mucosal cancer post surgery is locoregional recurrence. We tried to figure out how close the surgical margin being unsafe and needed further adjuvant treatment.

    Authors: Wen-Yen Chiou, Hon-Yi Lin, Feng-Chun Hsu, Moon-Sing Lee, Hsu-Chueh Ho, Yu-Chieh Su, Ching-Chih Lee, Chen-Hsi Hsieh, Yao-Ching Wang and Shih-Kai Hung
    Citation: Radiation Oncology 2010 5:79
    Content type: Research Published on:

  11. To investigate the significance of monitoring the levels of the serum squamous cell carcinoma antigen (SCC-Ag) for the detection of recurrent disease in patients with cervical cancer treated by concurrent chem...

    Authors: Sang Min Yoon, Kyung Hwan Shin, Joo-Young Kim, Sang Soo Seo, Sang-Yoon Park, Sung Ho Moon and Kwan Ho Cho
    Citation: Radiation Oncology 2010 5:78
    Content type: Research Published on:

  12. Stereotactic-Radio-Surgery (SRS) using Conformal-Arc-Therapy (CAT) is a well established irradiation technique for treatment of intracranial targets. Although small safety margins are required because of very ...

    Authors: Hendrik A Wolff, Daniela M Wagner, Hans Christiansen, Clemens F Hess and Hilke Vorwerk
    Citation: Radiation Oncology 2010 5:77
    Content type: Research Published on:

  13. To define a suitable threshold setting for gross tumor volume (GTV) when using 18Fluoro-deoxyglucose positron emission tomography and computed tomogram (PET/CT) for radiotherapy planning in head and neck cancer (...

    Authors: Chia-Hung Kao, Te-Chun Hsieh, Chun-Yen Yu, Kuo-Yang Yen, Shih-Neng Yang, Yao-Ching Wang, Ji-An Liang, Chun-Ru Chien and Shang-Wen Chen
    Citation: Radiation Oncology 2010 5:76
    Content type: Research Published on:

  14. Synchronous liver metastases are detected in approximately 25% of colorectal cancer patients at diagnosis. The rates of local failure and distant metastasis are substantial in these patients, even after underg...

    Authors: Jun Won Kim, Yong Bae Kim, Nam-Kyu Kim, Byung-Soh Min, Sang Joon Shin, Joong Bae Ahn, Woong Sub Koom, Jinsil Seong and Ki Chang Keum
    Citation: Radiation Oncology 2010 5:75
    Content type: Research Published on:

  15. Intensity modulated radiation therapy (IMRT) has been incorporated at several institutions for early stage laryngeal cancer (T1/T2N0M0), but its utility is controversial.

    Authors: Daniel Gomez, Oren Cahlon, James Mechalakos and Nancy Lee
    Citation: Radiation Oncology 2010 5:74
    Content type: Research Published on:

  16. To define the clinical target volume (CTV) for radiotherapy in patients with hepatocellular carcinoma (HCC).

    Authors: Weihu Wang, Xiaoli Feng, Tao Zhang, Jing Jin, Shulian Wang, Yueping Liu, Yongwen Song, Xinfan Liu, Zihao Yu and Yexiong LI
    Citation: Radiation Oncology 2010 5:73
    Content type: Research Published on:

  17. Our previous study showed a close relationship between computed tomography (CT)-derived bidimensional measurement of primary tumor and retropharyngeal nodes (BDMprn) and gross tumor volume of primary tumor and...

    Authors: Ting-Shou Chang, Sau-Tung Chu, Yu-Yi Hou, Kuo-Ping Chang, Chao-Chuan Chi and Ching-Chih Lee
    Citation: Radiation Oncology 2010 5:72
    Content type: Research Published on:

  18. We have previously shown that in vitro radiosensitivity of human tumor cells segregate non-randomly into a limited number of groups. Each group associates with a specific genotype. However we have also shown t...

    Authors: Jerry R Williams, Yonggang Zhang, Haoming Zhou, Daila S Gridley, Cameron J Koch, John F Dicello, James M Slater and John B Little
    Citation: Radiation Oncology 2010 5:71
    Content type: Research Published on:

  19. Overexpression of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is commonly occurred in cancers and causes radioresistance and poor prognosis. In present study, the single-chain variable antibody f...

    Authors: Li Du, Li-Jun Zhou, Xiu-Jie Pan, Yu-Xiao Wang, Qin-Zhi Xu, Zhi-Hua Yang, Yu Wang, Xiao-Dan Liu, Mao-Xiang Zhu and Ping-Kun Zhou
    Citation: Radiation Oncology 2010 5:70
    Content type: Research Published on:

  20. We evaluated outcomes of patients treated with external beam radiotherapy (EBRT) for locoregionally advanced or recurrent nonanaplastic thyroid cancer and analyzed the effect of EBRT volume on locoregional con...

    Authors: Tae Hyun Kim, Ki-Wook Chung, You Jin Lee, Chan Sung Park, Eun Kyung Lee, Tae Sung Kim, Seok Ki Kim, Yoo Seok Jung, Jun Sun Ryu, Sang Soo Kim, Kwan Ho Cho and Kyung Hwan Shin
    Citation: Radiation Oncology 2010 5:69
    Content type: Research Published on:

  22. A modified form of high dose rate (HDR) brachytherapy has been developed called Axxent Electronic Brachytherapy (EBT). EBT uses a kilovolt X-ray source and does not require treatment in a shielded vault or a H...

    Authors: Adam Dickler, Mohamed Y Puthawala, John P Thropay, Ajay Bhatnagar and Gary Schreiber
    Citation: Radiation Oncology 2010 5:67
    Content type: Research Published on:

  23. Telomerase activity compensates shortening of telomeres during cell division and enables cancer cells to escape senescent processes. It is also supposed, that telomerase is associated with radio- and chemoresi...

    Authors: Simone Wesbuer, Claudia Lanvers-Kaminsky, Ines Duran-Seuberth, Tobias Bölling, Karl-Ludwig Schäfer, Yvonne Braun, Normann Willich and Burkhard Greve
    Citation: Radiation Oncology 2010 5:66
    Content type: Research Published on:

  24. To study the impacts of multileaf collimators (MLC) width [standard MLC width of 10 mm (sMLC) and micro-MLC width of 4 mm (mMLC)] in the intensity-modulated radiotherapy (IMRT) planning for the upper thoracic ...

    Authors: Youling Gong, Shichao Wang, Lin Zhou, Yongmei Liu, Yong Xu, You Lu, Sen Bai, Yuchuan Fu, Qingfeng Xu and Qingfeng Jiang
    Citation: Radiation Oncology 2010 5:65
    Content type: Research Published on:

  26. Chemoradiation for cervical cancer patients is associated with considerable gastrointestinal toxicity. Intensity-modulated radiotherapy (IMRT) has demonstrated superiority in terms of target coverage and norma...

    Authors: Carmen Stromberger, Yves Kom, Michael Kawgan-Kagan, Tristan Mensing, Ulrich Jahn, Achim Schneider, Volker Budach, Christhardt Köhler and Simone Marnitz
    Citation: Radiation Oncology 2010 5:63
    Content type: Research Published on:

  27. Because of superior soft tissue contrast, the use of magnetic resonance imaging (MRI) as a complement to computed tomography (CT) in the target definition procedure for radiotherapy is increasing. To keep the ...

    Authors: Joakim H Jonsson, Magnus G Karlsson, Mikael Karlsson and Tufve Nyholm
    Citation: Radiation Oncology 2010 5:62
    Content type: Research Published on:

  28. Scanned ion beam therapy of intra-fractionally moving tumors requires motion mitigation. GSI proposed beam tracking and performed several experimental studies to analyse the dosimetric precision of the system ...

    Authors: Christoph Bert, Alexander Gemmel, Nami Saito, Naved Chaudhri, Dieter Schardt, Marco Durante, Gerhard Kraft and Eike Rietzel
    Citation: Radiation Oncology 2010 5:61
    Content type: Research Published on:

  29. Helical tomotherapy, an advanced intensity-modulated radiation therapy with integrated CT imaging, permits highly conformal irradiation with sparing of normal tissue. Capecitabine, a pro-drug of 5-FU that indu...

    Authors: Jeong-Seon Ji, Chi-Wha Han, Jeong-Won Jang, Bo-In Lee, Byung-Wook Kim, Hwang Choi, Ji-Yoon Kim, Young-Nam Kang, Chul-Seung Kay and Ihl-Bohng Choi
    Citation: Radiation Oncology 2010 5:60
    Content type: Research Published on:

  30. 1. To determine the optimal pelvic nodal clinical target volume for post-operative treatment of endometrial cancer. 2. To compare the DVH of different treatment planning techniques applied to this new CTV and ...

    Authors: Susan Guo, Ronald D Ennis, Stephen Bhatia, Frieda Trichter, Benjamin Bashist, Jinesh Shah and Manjeet Chadha
    Citation: Radiation Oncology 2010 5:59
    Content type: Research Published on:

  31. Dosimetric evaluations of single and multiple liver tumours performed using intensity-modulated helical tomotherapy (HT) were quantitatively investigated. Step-and-shoot intensity-modulated radiotherapy (SaS-I...

    Authors: Tsair-Fwu Lee, Pei-Ju Chao, Fu-Min Fang, Te-Jen Su, Stephen W Leung and Hsuan-Chih Hsu
    Citation: Radiation Oncology 2010 5:58
    Content type: Research Published on:

  32. To quantify the radiobiological advantages obtained by an Improved Forward Planning technique (IFP) and two IMRT techniques using different fractionation schemes for the irradiation of head and neck tumours. T...

    Authors: Brigida C Ferreira, Maria do Carmo Lopes, Josefina Mateus, Miguel Capela and Panayiotis Mavroidis
    Citation: Radiation Oncology 2010 5:57
    Content type: Research Published on:

  33. To investigate the efficacy and safety of accelerated partial breast irradiation (APBI) via high-dose-rate (HDR) multicatheter interstitial brachytherapy for early-stage breast cancer.

    Authors: Seung-Gu Yeo, Juree Kim, Geum-Hee Kwak, Ji-Young Kim, Kyeongmee Park, Eun Seok Kim and Sehwan Han
    Citation: Radiation Oncology 2010 5:56
    Content type: Research Published on:

  34. Standard therapy for soft-tissue sarcomas remains complete resection. For primary radiotherapy local control rates of 30-45% have been reported. We analyzed retrospectively 11 cases of radiochemotherapy with s...

    Authors: Franziska Eckert, Christiane Matuschek, Arndt-Christian Mueller, Martin Weinmann, Joerg T Hartmann, Claus Belka and Wilfried Budach
    Citation: Radiation Oncology 2010 5:55
    Content type: Research Published on:

  35. To report about initial clinical experience in radiation treatment of carcinoma of prostate with volumetric modulated arcs with the RapidArc (RA) technology.

    Authors: Gianfranco A Pesce, Alessandro Clivio, Luca Cozzi, Giorgia Nicolini, Antonella Richetti, Emanuela Salati, Mariacarla Valli, Eugenio Vanetti and Antonella Fogliata
    Citation: Radiation Oncology 2010 5:54
    Content type: Research Published on:

  36. The application of lipiodol injections as markers around bladder tumors combined with the use of CBCT for image guidance enables daily on-line position correction based on the position of the bladder tumor. Ho...

    Authors: Dominique C van Rooijen, René Pool, Jeroen B van de Kamer, Maarten CCM Hulshof, Caro CE Koning and Arjan Bel
    Citation: Radiation Oncology 2010 5:53
    Content type: Research Published on:

  37. Fiducial markers and daily electronic portal imaging (EPI) can reduce the risk of geographic miss in prostate cancer radiotherapy. The purpose of this study was to estimate CTV to PTV margin requirements, with...

    Authors: David Skarsgard, Pat Cadman, Ali El-Gayed, Robert Pearcey, Patricia Tai, Nadeem Pervez and Jackson Wu
    Citation: Radiation Oncology 2010 5:52
    Content type: Research Published on:

  38. The aim of this study is to examine the effect of stereotactic radiosurgery (SRS) in the treatment of advanced, recurrent lesions for head and neck carcinoma both with and without lymph node involvement.

    Authors: Koji Kawaguchi, Kengo Sato, Akihisa Horie, Susumu Iketani, Hiroyuki Yamada, Yasunori Nakatani, Junichi Sato and Yoshiki Hamada
    Citation: Radiation Oncology 2010 5:51
    Content type: Research Published on:

  39. Studies have shown that surgery alone is less than satisfactory in the management of early gastric cancer, with cure rates approaching 40%. The role of adjuvant therapy was indefinite until three large, random...

    Authors: Philippe G Aftimos, Elie A Nasr, Dolly I Nasr, Roger J Noun, Fady L Nasr, Marwan G Ghosn, Joelle A El Helou and Georges Y Chahine
    Citation: Radiation Oncology 2010 5:50
    Content type: Research Published on:

  40. A 46 year old male patient with metastatic prostate cancer developed Stevens-Johnson syndrome (SJS), initially in three well-demarcated areas on his scalp, chest and back, corresponding to ports of radiation t...

    Authors: Abdullah O Kandil, Tomas Dvorak, John Mignano, Julian K Wu and Jay-Jiguang Zhu
    Citation: Radiation Oncology 2010 5:49
    Content type: Case report Published on:

  41. To evaluate and compare the biological impact on different proposed margin recipes for the same geometric uncertainties for intra-hepatic tumors with different tumor cell types or clinical stages.

    Authors: Hsiang-Chi Kuo, Wen-Shan Liu, Andrew Wu, Dennis Mah, Keh-Shih Chuang, Linda Hong, Ravi Yaparpalvi, Chandan Guha and Shalom Kalnicki
    Citation: Radiation Oncology 2010 5:48
    Content type: Research Published on:

  42. Although neoadjuvant chemoradiotherapy (CRT) is the standard treatment for advanced rectal cancer (RC), markers to predict the treatment response have not been fully established. In 73 patients with advanced R...

    Authors: Joji Kitayama, Koji Yasuda, Kazushige Kawai, Eiji Sunami and Hirokazu Nagawa
    Citation: Radiation Oncology 2010 5:47
    Content type: Short report Published on:

  43. This study explores whether meningioma expresses epidermal growth factor receptor (EGFR) and determines if there is a correlation between the WHO grade of this tumor and the degree of EGFR expression.

    Authors: A Gabriella Wernicke, Adam P Dicker, Michal Whiton, Jana Ivanidze, Terry Hyslop, Elizabeth H Hammond, Arie Perry, David W Andrews and Lawrence Kenyon
    Citation: Radiation Oncology 2010 5:46
    Content type: Short report Published on:

  44. Thoracic cancer treatment presents dosimetric difficulties due to respiratory motion and lung inhomogeneity. Monte Carlo and deformable image registration techniques have been proposed to be used in four-dimen...

    Authors: Tzung-Chi Huang, Ji-An Liang, Thomas Dilling, Tung-Hsin Wu and Geoffrey Zhang
    Citation: Radiation Oncology 2010 5:45
    Content type: Research Published on:

  45. To assess radiobiological restrictions and tolerance doses as well as other toxic effects derived from repeated applications of single-fraction high dose rate irradiation of small liver volumes in clinical pra...

    Authors: Ricarda Rühl, Lutz Lüdemann, Anna Czarnecka, Florian Streitparth, Max Seidensticker, Konrad Mohnike, Maciej Pech, Peter Wust and Jens Ricke
    Citation: Radiation Oncology 2010 5:44
    Content type: Research Published on:

  46. The aim of this study was to assess the results of curative surgery with and without radiotherapy in patients with T1-2N0-1 oral tongue squamous cell carcinoma (OSCC) and to evaluate survival and prognostic facto...

    Authors: Su Jung Shim, Jihye Cha, Woong Sub Koom, Gwi Eon Kim, Chang Geol Lee, Eun Chang Choi and Ki Chang Keum
    Citation: Radiation Oncology 2010 5:43
    Content type: Research Published on:

  49. To compare the differences in dose-volume data among coplanar intensity modulated radiotherapy (IMRT), noncoplanar IMRT, and helical tomotherapy (HT) among patients with hepatocellular carcinoma (HCC) and port...

    Authors: Chen-Hsi Hsieh, Chia-Yuan Liu, Pei-Wei Shueng, Ngot-Swan Chong, Chih-Jen Chen, Ming-Jen Chen, Ching-Chung Lin, Tsang-En Wang, Shee-Chan Lin, Hung-Chi Tai, Hui-Ju Tien, Kuo-Hsin Chen, Li-Ying Wang, Yen-Ping Hsieh, David YC Huang and Yu-Jen Chen
    Citation: Radiation Oncology 2010 5:40
    Content type: Research Published on:

  50. Concurrent platinum-based radiochemotherapy has been recommended as a standard of care in patients with locally advanced squamous cell head and neck carcinomas. Unfortunately, there is a lack of level one evid...

    Authors: Valentina Krstevska, Igor Stojkovski and Dusko Lukarski
    Citation: Radiation Oncology 2010 5:39
    Content type: Research Published on:
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Radiation Oncology

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