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  1. An important issue in palliative radiation oncology is the whether whole-brain radiotherapy should be added to radiosurgery when treating a limited number of brain metastases. To optimize personalized treatmen...

    Authors: Dirk Rades, Stefan Huttenlocher, Dagmar Hornung, Oliver Blanck, Steven E Schild and Dorothea Fischer
    Citation: Radiation Oncology 2014 9:267
    Content type: Research Published on:

  3. In previous experiments an enhanced anti-proliterative effect of the EGFR/ErbB tyrosine kinase inhibitor (TKI) BIBW 2992 with single dose irradiation was observed in FaDu tumour xenografts. Aim of the present ...

    Authors: Kristin Gurtner, Nadja Ebert, Dorothee Pfitzmann, Wolfgang Eicheler, Daniel Zips, Michael Baumann and Mechthild Krause
    Citation: Radiation Oncology 2014 9:261
    Content type: Research Published on:

  4. POEMS syndrome is a paraneoplastic syndrome caused by an underlying plasma cell proliferative disease. In this study, we examined the treatment outcomes and role of radiotherapy in the management of POEMS synd...

    Authors: Yang-Gun Suh, Young-Suk Kim, Chang-Ok Suh, Yu Ri Kim, June-Won Cheong, Jin Seok Kim and Jaeho Cho
    Citation: Radiation Oncology 2014 9:265
    Content type: Research Published on:

  5. To determine prostate displacement during extreme hypofractionated volume modulated arc radiotherapy (VMAT) using pre- and post-treatment orthogonal images with three implanted gold seed fiducial markers.

    Authors: Adam Gladwish, Geordi Pang, Patrick Cheung, Laura D’Alimonte, Andrea Deabreu and Andrew Loblaw
    Citation: Radiation Oncology 2014 9:262
    Content type: Research Published on:

  6. TomoTherapy (Accuray, USA) has an image-guided radiotherapy system with a megavoltage (MV) X-ray source and an on-board imaging device. This system allows one to acquire the delivery sinogram during the actual...

    Authors: Akihiro Haga, Keiichi Nakagawa, Calvin Maurer, Ken Ruchala, Edward Chao, Dylan Casey, Satoshi Kida, Dousatsu Sakata, Masahiro Nakano, Taiki Magome and Yoshitaka Masutani
    Citation: Radiation Oncology 2014 9:252
    Content type: Short report Published on:

  7. Due to substantial improvement in diagnosis and treatment of oral cavity cancer, a better understanding of the patient care needs to be revised. We reviewed literature related to OCC and discussed current gene...

    Authors: Francesca De Felice, Daniela Musio, Valentina Terenzi, Valentino Valentini, Andrea Cassoni, Mario Tombolini, Marco De Vincentiis and Vincenzo Tombolini
    Citation: Radiation Oncology 2014 9:263
    Content type: Review Published on:

  8. Retrospective, monocentric analysis of localized superior sulcus non-small cell cancer (SS-NSCLC), article management.

    Authors: Pierre Truntzer, Delphine N Antoni, Nicola Santelmo, Catherine Schumacher, Pierre-Emmanuel Falcoz, Elisabeth Quoix, Jean-Pierre Steib, Gilbert Massard and Georges Noël
    Citation: Radiation Oncology 2014 9:259
    Content type: Case report Published on:

  9. The prognostic factors of thoracic esophageal squamous carcinoma with cervical lymph nodal metastasis (CLNM) have not been specifically investigated. This study was performed to analyze the efficacy and progno...

    Authors: Peng Zhang, Mian Xi, Lei Zhao, Qiao-Qiao Li, Li-Ru He, Shi-Liang Liu, Jing-Xian Shen and Meng-Zhong Liu
    Citation: Radiation Oncology 2014 9:256
    Content type: Research Published on:

  10. Saliva from submandibular glands (SMG) is necessary to minimize xerostomia. It is unclear whether SMG can be safely spared in patients undergoing bilateral neck radiotherapy for locally advanced oropharyngeal ...

    Authors: Michael F Gensheimer, Jay J Liao, Adam S Garden, George E Laramore and Upendra Parvathaneni
    Citation: Radiation Oncology 2014 9:255
    Content type: Research Published on:

  11. Stereotactic ablative body radiotherapy (SABR) has been proposed as a definitive treatment for patients with inoperable primary renal cell carcinoma. However, there is little documentation detailing the radiob...

    Authors: Price Jackson, Farshad Foroudi, Daniel Pham, Michael S Hofman, Nicholas Hardcastle, Jason Callahan, Tomas Kron and Shankar Siva
    Citation: Radiation Oncology 2014 9:253
    Content type: Short report Published on:

  12. There as yet exists no systematic planning study investigating the novel mARC rotational radiotherapy technique, which is conceptually different from VMAT. We therefore present a planning study for prostate ca...

    Authors: Yvonne Dzierma, Katharina Bell, Jan Palm, Frank Nuesken, Norbert Licht and Christian Rübe
    Citation: Radiation Oncology 2014 9:250
    Content type: Research Published on:

  13. In modern radiotherapy, it is crucial to monitor the performance of all linac components including gantry, collimation system and electronic portal imaging device (EPID) during arc deliveries. In this study, a...

    Authors: Pejman Rowshanfarzad, Conor K McGarry, Michael P Barnes, Mahsheed Sabet and Martin A Ebert
    Citation: Radiation Oncology 2014 9:249
    Content type: Research Published on:

  14. The phase III 22071–26071 trial was designed to evaluate the addition of panitumumab to adjuvant chemotherapy plus intensity modulated radiotherapy (IMRT) in locally advanced resected squamous cell head and ne...

    Authors: Alysa Fairchild, Johannes A Langendijk, Sandra Nuyts, Christopher Scrase, Milan Tomsej, Danny Schuring, Akos Gulyban, Sunita Ghosh, Damien C Weber and Wilfried Budach
    Citation: Radiation Oncology 2014 9:248
    Content type: Research Published on:

  15. To evaluate and compare dosimetric parameters of volumetric modulated arctherapy (VMAT) and helical tomotherapy (HT) for non-anaplastic thyroid cancer adjuvant radiotherapy.

    Authors: Jonathan Khalifa, Laure Vieillevigne, Sabrina Boyrie, Monia Ouali, Thomas Filleron, Michel Rives and Anne Laprie
    Citation: Radiation Oncology 2014 9:247
    Content type: Research Published on:

  16. Cigarette smoking is a common risk factor for developing nasopharyngeal carcinoma. However, the relationship between smoking and clinical outcomes remains uncertain.

    Authors: Shan-Shan Guo, Pei-Yu Huang, Qiu-Yan Chen, Huai Liu, Lin-Quan Tang, Lu Zhang, Li-Ting Liu, Ka-Jia Cao, Ling Guo, Hao-Yuan Mo, Xiang Guo, Ming-Huang Hong and Hai-Qiang Mai
    Citation: Radiation Oncology 2014 9:246
    Content type: Research Published on:

  17. The optimal clinical context for initiation of salvage androgen deprivation therapy (SADT) following the biochemical recurrence of localized prostate cancer remains controversial. We chose to investigate if di...

    Authors: Corey C Foster, William C Jackson, Benjamin C Foster, Skyler B Johnson, Felix Y Feng and Daniel A Hamstra
    Citation: Radiation Oncology 2014 9:245
    Content type: Research Published on:

  18. To evaluate the technical feasibility and toxicity of TomoDirect in breast cancer patients who received radiotherapy after breast-conserving surgery.

    Authors: Hyo Chun Lee, Sung Hwan Kim, Young Jin Suh, Mi Joo Chung, Dae Gyu Kang, Hyun Joo Choi and Jong Hoon Lee
    Citation: Radiation Oncology 2014 9:244
    Content type: Research Published on:

  19. To precisely calculate skin dose and thus to evaluate the relationship between the skin dose and permanent alopecia for pediatric medulloblastoma patients treated with proton beams.

    Authors: Chul Hee Min, Harald Paganetti, Brian A Winey, Judith Adams, Shannon M MacDonald, Nancy J Tarbell and Torunn I Yock
    Citation: Radiation Oncology 2014 9:220
    Content type: Research Published on:

  20. Patients with large prostate volumes have been shown to have higher rates of genitourinary and gastrointestinal toxicities after conventional radiation therapy for prostate cancer. The efficacy and toxicity of...

    Authors: Einsley Janowski, Leonard N Chen, Joy S Kim, Siyuan Lei, Simeng Suy, Brian Collins, John Lynch, Anatoly Dritschilo and Sean Collins
    Citation: Radiation Oncology 2014 9:241
    Content type: Research Published on:

  22. The aim of this study was to report the outcome of primary or metastatic lung cancer patients undergoing volumetric modulated arc therapy for stereotactic body radiation therapy (VMAT-SBRT).

    Authors: Hideomi Yamashita, Akihiro Haga, Wataru Takahashi, Ryousuke Takenaka, Toshikazu Imae, Shigeharu Takenaka and Keiichi Nakagawa
    Citation: Radiation Oncology 2014 9:243
    Content type: Research Published on:

  23. To moving lung tumors, we applied a respiratory-gated strategy to carbon-ion pencil beam scanning with multiple phase-controlled rescanning (PCR). In this simulation study, we quantitatively evaluated dose dis...

    Authors: Wataru Takahashi, Shinichiro Mori, Mio Nakajima, Naoyoshi Yamamoto, Taku Inaniwa, Takuji Furukawa, Toshiyuki Shirai, Koji Noda, Keiichi Nakagawa and Tadashi Kamada
    Citation: Radiation Oncology 2014 9:238
    Content type: Research Published on:

  24. To evaluate PTV margins for hypofractionated IGRT of prostate comparing kV/kV imaging or CBCT.

    Authors: Christoph Oehler, Stephanie Lang, Peter Dimmerling, Christian Bolesch, Stephan Kloeck, Alessandra Tini, Christoph Glanzmann, Yousef Najafi, Gabriela Studer and Daniel R Zwahlen
    Citation: Radiation Oncology 2014 9:229
    Content type: Research Published on:

  25. Glioblastoma multiforme (GBM) frequently recurs at the same location after radiotherapy. Further dose escalation using conventional methods is limited by normal tissue tolerance. 4Ï€ non-coplanar radiotherapy h...

    Authors: Dan Nguyen, Jean-Claude M Rwigema, Victoria Y Yu, Tania Kaprealian, Patrick Kupelian, Michael Selch, Percy Lee, Daniel A Low and Ke Sheng
    Citation: Radiation Oncology 2014 9:239
    Content type: Research Published on:

  28. We treated a 54-year-old Japanese female with a recurrent radiation-induced osteosarcoma arising from left occipital skull, by reactor-based boron neutron capture therapy (BNCT). Her tumor grew rapidly with su...

    Authors: Gen Futamura, Shinji Kawabata, Hiroyuki Siba, Toshihiko Kuroiwa, Minoru Suzuki, Natsuko Kondo, Koji Ono, Yoshinori Sakurai, Minoru Tanaka, Tomoki Todo and Shin-Ichi Miyatake
    Citation: Radiation Oncology 2014 9:237
    Content type: Case report Published on:

  29. To investigate the feasibility of constant dose rate volumetric modulated arc therapy (CDR-VMAT) in the treatment of nasopharyngeal cancer (NPC) patients and to introduce rotational arc radiotherapy for linacs...

    Authors: Wenliang Yu, Haijiao Shang, Congying Xie, Ce Han, Jinling Yi, Yongqiang Zhou and Xiance Jin
    Citation: Radiation Oncology 2014 9:235
    Content type: Research Published on:

  30. A brainstorming and consensus meeting organized by the German Cancer Aid focused on modern treatment of prostate cancer and promising innovative techniques and research areas. Besides optimization of screening...

    Authors: Stephanie E Combs, Jürgen Debus, Günter Feick, Boris Hadaschik, Markus Hohenfellner, Roland Schüle, Jens-Peter Zacharias and Malte Schwardt
    Citation: Radiation Oncology 2014 9:224
    Content type: Research Published on:

  31. Intensity modulated arc therapy (IMAT) has been widely adopted for Stereotactic Body Radiotherapy (SBRT) for lung cancer. While treatment dose is optimized and calculated on a static Computed Tomography (CT) i...

    Authors: Wei Zou, Lingshu Yin, Jiajian Shen, Michael N Corradetti, Maura Kirk, Reshma Munbodh, Penny Fang, Salma K Jabbour, Charles B Simone, Ning J Yue, Ramesh Rengan and Boon-Keng Kevin Teo
    Citation: Radiation Oncology 2014 9:225
    Content type: Research Published on:

  32. The standard treatment choice for cancer metastasis has been systemic management, including cytotoxic chemotherapy, hormonal manipulation, and targeted therapy. Emerging evidence has shown an oligometastatic s...

    Authors: Fang Huang, Gang Wu and Kunyu Yang
    Citation: Radiation Oncology 2014 9:230
    Content type: Review Published on:

  33. To evaluate in-silico the performance of a model-based optimization process for volumetric modulated arc therapy (RapidArc) applied to hepatocellular cancer treatments.

    Authors: Antonella Fogliata, Po-Ming Wang, Francesca Belosi, Alessandro Clivio, Giorgia Nicolini, Eugenio Vanetti and Luca Cozzi
    Citation: Radiation Oncology 2014 9:236
    Content type: Research Published on:

  34. Increased caseload has been associated with better patient outcomes in many areas of health care, including high-risk surgery and cancer treatment. However, such a positive volume vs. outcome relationship has ...

    Authors: Moon-Sing Lee, Shiang-Jiun Tsai, Ching-Chih Lee, Yu-Chieh Su, Wen-Yen Chiou, Hon-Yi Lin and Shih-Kai Hung
    Citation: Radiation Oncology 2014 9:234
    Content type: Research Published on:

  35. A retrospective study to compare the failure patterns and effects of elective nodal irradiation (ENI) or involved field irradiation (IFI) for cervical and upper thoracic esophageal squamous cell carcinoma (SCC...

    Authors: Mina Liu, Kuaile Zhao, Yun Chen and Guo-Liang Jiang
    Citation: Radiation Oncology 2014 9:232
    Content type: Research Published on:

  36. Preoperative chemoradiotherapy is usually not indicated for cT2N0 rectal cancer. Abdominoperineal resection is the standard treatment for distal rectal tumors. The aim of the study was to evaluate the actual s...

    Authors: Nir Wasserberg, Yulia Kundel, Ofer Purim, Andrei Keidar, Hanoch Kashtan, Eran Sadot, Eyal Fenig and Baruch Brenner
    Citation: Radiation Oncology 2014 9:233
    Content type: Research Published on:

  37. Treatment options for patients with recurrent disease after radical prostatectomy include salvage radiotherapy of the prostatic bed and/or androgen deprivation therapy. To establish an effective treatment stra...

    Authors: Makito Miyake, Nobumichi Tanaka, Isao Asakawa, Yosuke Morizawa, Satoshi Anai, Kazumasa Torimoto, Katsuya Aoki, Tatsuo Yoneda, Masatoshi Hasegawa, Noboru Konishi and Kiyohide Fujimoto
    Citation: Radiation Oncology 2014 9:208
    Content type: Research Published on:

  38. A single-institutional prospective study of optimal hypofractionated conformal radiotherapy for large brain metastases with high risk factors was performed based on the risk prediction of radiation-related com...

    Authors: Hiroshi K Inoue, Hiro Sato, Yoshiyuki Suzuki, Jun-ichi Saitoh, Shin-ei Noda, Ken-ichi Seto, Kota Torikai, Hideyuki Sakurai and Takashi Nakano
    Citation: Radiation Oncology 2014 9:231
    Content type: Research Published on:

  39. Hypoxia and increased glycolytic activity of tumors are associated with poor prognosis. The purpose of this study was to investigate differences in radiotherapy (RT) dose painting based on the uptake of 2-deox...

    Authors: Malene Martini Clausen, Anders Elias Hansen, Michael Lundemann, Christian Hollensen, Tobias Pommer, Per Munck af Rosenschöld, Annemarie Thuri Kristensen, Andreas Kjær, Fintan J McEvoy and Svend Aage Engelholm
    Citation: Radiation Oncology 2014 9:228
    Content type: Research Published on:

  40. Radiotherapy for long bone metastases (RTLB) can be complicated by fractures, which considerably increase morbidity and mortality. The aim of this study was to analyze the risk factors for impending fractures ...

    Authors: Zuzana Tatar, Martin Soubrier, Anne Françoise Dillies, Pierre Verrelle, Stéphane Boisgard and Michel Lapeyre
    Citation: Radiation Oncology 2014 9:227
    Content type: Research Published on:

  41. To evaluate patient selection criteria, methodology, safety and clinical outcomes of stereotactic body radiotherapy (SBRT) for treatment of vertebral metastases.

    Authors: Matthias Guckenberger, Frederick Mantel, Peter C Gerszten, John C Flickinger, Arjun Sahgal, Daniel Létourneau, Inga S Grills, Maha Jawad, Daniel K Fahim, John H Shin, Brian Winey, Jason Sheehan and Ron Kersh
    Citation: Radiation Oncology 2014 9:226
    Content type: Research Published on:

  42. The aim of current study was to investigate the way dose is prescribed to lung lesions during SBRT using advanced dose calculation algorithms that take into account electron transport (type B algorithms). As t...

    Authors: Thomas Lacornerie, Albert Lisbona, Xavier Mirabel, Eric Lartigau and Nick Reynaert
    Citation: Radiation Oncology 2014 9:223
    Content type: Methodology Published on:

  43. Interstitial brachytherapy (ISBT) is an optional treatment for locally advanced gynecological tumours for which conventional intracavitary brachytherapy (ICBT) would result in suboptimal dose coverage. However...

    Authors: Takahiro Oike, Tatsuya Ohno, Shin-ei Noda, Hiroki Kiyohara, Ken Ando, Kei Shibuya, Tomoaki Tamaki, Yosuke Takakusagi, Hiro Sato and Takashi Nakano
    Citation: Radiation Oncology 2014 9:222
    Content type: Research Published on:

  44. To study the feasibility and the potential benefits of defining the internal gross tumor volume (IGTV) of hepatocellular carcinoma (HCC) using contrast-enhanced 4D CT images obtained by combining arterial-phas...

    Authors: Hua Xu, Guanzhong Gong, Hong Wei, Lusheng Chen, Jinhu Chen, Jie Lu, Tonghai Liu, Jian Zhu and Yong Yin
    Citation: Radiation Oncology 2014 9:221
    Content type: Research Published on:

  45. To compare the dosimetric differences among fixed field intensity-modulated radiation therapy (IMRT), single-arc volumetric-modulated arc therapy (SA-VMAT) and double-arc volumetric-modulated arc therapy (DA-V...

    Authors: Jun Shang, Wei Kong, Yan-yang Wang, Zhe Ding, Gang Yan and Hong Zhe
    Citation: Radiation Oncology 2014 9:219
    Content type: Research Published on:

  46. Dang and colleagues recently reported in the journal that tumor response to definitive chemoradiation, as assessed using the RECIST criteria, and the risk of radiation pneumonitis were positively correlated in...

    Authors: Michael P MacManus, David Ball and Rodney J Hicks
    Citation: Radiation Oncology 2014 9:217
    Content type: Letter to the Editor Published on:

  47. Yomo and Hayashi reported results of stereotactic radiosurgery alone for brainmetastases from small cell lung cancer. This strategy aims to avoid theneurocognitive effects of whole-brain radiation therapy. How...

    Authors: Eric Ojerholm, Michelle Alonso-Basanta and Charles B Simone II
    Citation: Radiation Oncology 2014 9:218
    Content type: Letter to the Editor Published on:

  48. To evaluate efficacy and toxicity of hypofractionated intensity-modulated simultaneous integrated boost (IMRT-SIB) and image-guided (IGRT) radiotherapy in the treatment of high-risk prostate cancer patients.

    Authors: Maurizio Valeriani, Alessia Carnevale, Mattia Falchetto Osti, Vitaliana DE Sanctis, Linda Agolli and Riccardo Maurizi Enrici
    Citation: Radiation Oncology 2014 9:214
    Content type: Research Published on:

  49. Gated Volumetric Modulated Arc Therapy (VMAT) is an emerging radiation therapy modality for treatment of tumors affected by respiratory motion. However, gating significantly prolongs the treatment time, as del...

    Authors: Benjamin Fahimian, Junqing Wu, Huanmei Wu, Sarah Geneser and Lei Xing
    Citation: Radiation Oncology 2014 9:209
    Content type: Research Published on:

  50. To retrospectively review the efficacy and organ preservation experience for muscle-invasive bladder cancer by trimodality therapy at our institution.

    Authors: Cheng-Yen Lee, Kai-Lin Yang, Hui-Ling Ko, Rong-Yau Huang, Pei-Pin Tsai, Ming-Tsun Chen, Yi-Chia Lin, Thomas I-Sheng Hwang, Guang-Dar Juang and Kwan-Hwa Chi
    Citation: Radiation Oncology 2014 9:213
    Content type: Research Published on:
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Radiation Oncology

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