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  1. We investigated the efficacy and safety of S-1 and cisplatin with concurrent thoracic radiation (SCCR) over cisplatin alone plus concurrent thoracic radiation (CCR) for unresectable stage III non-small-cell lu...

    Authors: Lei Yao, Shidong Xu, Jianyu Xu, Chaoyang Yang, Junfeng Wang and Dawei Sun
    Citation: Radiation Oncology 2015 10:10
    Content type: Research Published on:

  2. Investigating reproducibility and instability of deep inspiration breath hold (DIBH) in the prone position to reduce heart dose for left-sided whole breast irradiation.

    Authors: Thomas Mulliez, Liv Veldeman, Tom Vercauteren, Werner De Gersem, Bruno Speleers, Annick Van Greveling, Dieter Berwouts, Vincent Remouchamps, Rudy Van den Broecke and Wilfried De Neve
    Citation: Radiation Oncology 2015 10:9
    Content type: Research Published on:

  3. This study explores variables associated with poor prognosis in postoperative p16 positive oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing adjuvant radiotherapy or chemoradiotherapy. Specific...

    Authors: Vivek Verma, Jingxia Liu, Laura Eschen, Jonathan Danieley, Christopher Spencer, James S Lewis Jr, Jason Diaz, Jay F Piccirillo, Douglas R Adkins, Brian Nussenbaum, Wade L Thorstad and Hiram A Gay
    Citation: Radiation Oncology 2015 10:8
    Content type: Research Published on:

  4. Large anatomical variations occur during the course of intensity-modulated radiation therapy (IMRT) for locally advanced head and neck cancer (LAHNC). The risks are therefore a parotid glands (PG) overdose and...

    Authors: Joel Castelli, Antoine Simon, Guillaume Louvel, Olivier Henry, Enrique Chajon, Mohamed Nassef, Pascal Haigron, Guillaume Cazoulat, Juan David Ospina, Franck Jegoux, Karen Benezery and Renaud de Crevoisier
    Citation: Radiation Oncology 2015 10:6
    Content type: Research Published on:

  5. Thoracic and cardiac irradiation increases the risk of pulmonary and cardiovascular disease. In addition, radiation, often in combination with chemotherapy, can cause treatment-related pneumonitis. Previously,...

    Authors: Angera H Kuo, Marek Ancukiewicz, Kevin R Kozak, Torunn I Yock and Timothy P Padera
    Citation: Radiation Oncology 2015 10:5
    Content type: Short report Published on:

  6. Intratumoural heterogeneity has been demonstrated to be a strong indicator of malignant transformation. Our study was to investigate pretreatment 18 F-FDG parameters, including 18 F-FDG based heterogeneity for pr...

    Authors: Zhongyi Yang, Qi Shi, Yongping Zhang, Herong Pan, Zhifeng Yao, Silong Hu, Wei Shi, Beiling Zhu, Yingjian Zhang and Chaosu Hu
    Citation: Radiation Oncology 2015 10:4
    Content type: Research Published on:

  7. To determine the position and dose delivery changes rules of parotid gland (PG) during the course of intensity modulated radiation therapy (IMRT) in nasopharyngeal carcinoma patients (NPC).

    Authors: Wei Wang, Haihua Yang, Yucheng Mi, Wei Hu, Weijun Ding, Youyou Xie, Yujie Cai and Xiaofeng Chen
    Citation: Radiation Oncology 2015 10:3
    Content type: Research Published on:

  8. The purpose of the present study was to quantify the inter-fractional motion of the rectum and the rectal and bladder volumes using CBCT scans taken during chemoradiation therapy (CRT) for rectal cancer. Also,...

    Authors: Hideomi Yamashita, Ryousuke Takenaka, Akira Sakumi, Akihiro Haga, Kuni Otomo and Keiichi Nakagawa
    Citation: Radiation Oncology 2015 10:2
    Content type: Research Published on:

  9. Fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is an important method for detecting tumours, planning radiotherapy treatment, and evaluating treatment responses. However, u...

    Authors: Wataru Kawakami, Akihiro Takemura, Kunihiko Yokoyama, Kenichi Nakajima, Syoichi Yokoyama and Kichiro Koshida
    Citation: Radiation Oncology 2015 10:1
    Content type: Research Published on:

  10. To evaluate the effect of two different alpha-1 adrenoceptor antagonists on lower urinary tract symptoms in patients who underwent LDR-brachytherapy.

    Authors: Nobumichi Tanaka, Kazumasa Torimoto, Isao Asakawa, Makito Miyake, Satoshi Anai, Akihide Hirayama, Masatoshi Hasegawa, Noboru Konishi and Kiyohide Fujimoto
    Citation: Radiation Oncology 2014 9:302
    Content type: Research Published on:

  11. Radiation dermatitis is common in patients treated with combined radiotherapy and chemotherapy for head and neck malignancies. Its timely and adequate management is of uttermost importance for both oncological...

    Authors: Pierfrancesco Franco, Ilenia Potenza, Francesco Moretto, Mattia Segantin, Mario Grosso, Antonello Lombardo, Daniela Taricco, Patrizia Vallario, Andrea Riccardo Filippi, Monica Rampino and Umberto Ricardi
    Citation: Radiation Oncology 2014 9:297
    Content type: Research Published on:

  12. Performing intensity-modulated radiotherapy (IMRT) on head and neck cancer patients (HNCPs) requires robust training and experience. Thus, in 2011, the Head and Neck Cancer Working Group (HNCWG) of the Italian...

    Authors: Anna Merlotti, Daniela Alterio, Riccardo Vigna-Taglianti, Alessandro Muraglia, Luciana Lastrucci, Roberto Manzo, Giuseppina Gambaro, Orietta Caspiani, Francesco Miccichè, Francesco Deodato, Stefano Pergolizzi, Pierfrancesco Franco, Renzo Corvò, Elvio G Russi and Giuseppe Sanguineti
    Citation: Radiation Oncology 2014 9:264
    Content type: Review Published on:

  13. A 67-year old man with a history of papillary thyroid cancer (PTC) presented with metastatic disease to the left colon in the form of a 6.1x1.0 cm bleeding, ulcerated mass. Radiopaque surgical clips were used ...

    Authors: Alvin Szeto, Lee Chin, Patrick Whelan, Jennifer Wilson and Justin Lee
    Citation: Radiation Oncology 2014 9:298
    Content type: Case report Published on:

  14. Recurrence rates following radiotherapy for prostate cancer in the post-operative adjuvant or salvage setting remain substantial. Previous work from our institution demonstrated that published prostate bed CTV...

    Authors: Jennifer Croke, Jillian Maclean, Balazs Nyiri, Yan Li, Kyle Malone, Leonard Avruch, Cathleen Kayser and Shawn Malone
    Citation: Radiation Oncology 2014 9:303
    Content type: Research Published on:

  15. Management of spinal neoplasms has relied on open surgery and external beam radiotherapy (EBRT). Although primary spinal tumors are rare, their treatment remains a pervasive problem. This analysis sought to ev...

    Authors: Qianqian Cao, Hao Wang, Na Meng, Yuliang Jiang, Ping Jiang, Yang Gao, Suqing Tian, Chen Liu, Ruijie Yang, Junjie Wang and Kaixian Zhang
    Citation: Radiation Oncology 2014 9:301
    Content type: Research Published on:

  16. The aim of this study was to assess if FDG-PET could guide dose prescription heterogeneity and decrease arbitrary location of hotspots in SBRT.

    Authors: Bénédicte Henriques de Figueiredo, Mikael Antoine, Renaud Trouette, Philippe Lagarde, Adeline Petit, Frédéric Lamare, Mathieu Hatt and Philippe Fernandez
    Citation: Radiation Oncology 2014 9:300
    Content type: Research Published on:

  17. We investigated whether routine elective irradiation of a clinically negative inguinal node (IGN) is necessary for patients with locally advanced distal rectal cancer and anal canal invasion (ACI).

    Authors: Seung-Gu Yeo, Hyeon Woo Lim, Dae Yong Kim, Tae Hyun Kim, Sun Young Kim, Ji Yeon Baek, Hee Jin Chang, Ji Won Park and Jae Hwan Oh
    Citation: Radiation Oncology 2014 9:296
    Content type: Research Published on:

  18. To investigate systematic changes in dose arising when treatment plans optimised using the Anisotropic Analytical Algorithm (AAA) are recalculated using Acuros XB (AXB) in patients treated with definitive chem...

    Authors: Sriram Padmanaban, Samantha Warren, Anthony Walsh, Mike Partridge and Maria A Hawkins
    Citation: Radiation Oncology 2014 9:286
    Content type: Research Published on:

  19. The purpose of this study is to describe a novel brachytherapy technique for lip Squamous Cell Carcinoma, utilizing a customized mold with embedded brachytherapy sleeves, which separates the lip from the mandi...

    Authors: Jon Feldman, Limor Appelbaum, Mordechay Sela, Ninel Voskoboinik, Sarit Kadouri, Jeffrey Weinberger, Itzhak Orion and Amichay Meirovitz
    Citation: Radiation Oncology 2014 9:271
    Content type: Research Published on:

  20. The aim of the present analysis was to evaluate the recurrence pattern in patients with recurrent malignant glioma after re-irradiation in combination with bevacizumab as there is limited data on how to optima...

    Authors: Maximilian Niyazi, Nathalie Lisa Jansen, Maya Rottler, Ute Ganswindt and Claus Belka
    Citation: Radiation Oncology 2014 9:299
    Content type: Research Published on:

  21. The purpose of the study was to evaluate the feasibility of deformable image registration (DIR) in assessing cumulative dose distributions of the combination of external beam radiotherapy (EBRT) and fractionat...

    Authors: Takanori Abe, Tomoaki Tamaki, Souichi Makino, Takeshi Ebara, Ryuuta Hirai, Kazunori Miyaura, Yu Kumazaki, Tatsuya Ohno, Naoto Shikama, Takashi Nakano and Shingo Kato
    Citation: Radiation Oncology 2014 9:293
    Content type: Research Published on:

  22. Intermediate- to-high-risk prostate cancer can locally invade seminal vesicle (SV). It is recommended that anatomic proximal 1-cm to 2-cm SV be included in the clinical target volume (CTV) for definitive radio...

    Authors: Xin Qi, Xian-Shu Gao, Junichi Asaumi, Min Zhang, Hong-Zhen Li, Ming-Wei Ma, Bo Zhao, Fei-Yu Li and Dian Wang
    Citation: Radiation Oncology 2014 9:288
    Content type: Research Published on:

  23. Multi-atlas segmentation can yield better results than single atlas segmentation, but practical applications are limited by long calculation times for deformable registration. To shorten the calculation time p...

    Authors: Carl Sjöberg, Silvia Johansson and Anders Ahnesjö
    Citation: Radiation Oncology 2014 9:251
    Content type: Research Published on:

  24. The neutrophil-lymphocyte ratio (NLR) has been proposed as an indicator of systemic inflammatory response and may predict the clinical outcome in some cancers, such as head and neck cancer and gastric cancer. ...

    Authors: Lijun Shen, Hui Zhang, Liping Liang, Guichao Li, Ming Fan, Yongxin Wu, Ji Zhu and Zhen Zhang
    Citation: Radiation Oncology 2014 9:295
    Content type: Research Published on:

  25. The impact of thoracic three-dimensional radiotherapy on the prognosis for stage IV non-small-cell lung cancer is unclear. This study is to investigate survival outcomes and prognosis in patients with stage IV...

    Authors: ShengFa Su, YinXiang Hu, WeiWei Ouyang, Zhu Ma, Bing Lu, QingSong Li, HuiQin Li, ZhiYong Wang and Yu Wang
    Citation: Radiation Oncology 2014 9:290
    Content type: Research Published on:

  27. The aim of this study was to retrospectively observe and analyze the long-term treatment outcomes of a total of 140 esophageal cancer patients who were treated with californium-252 (252Cf) neutron brachytherapy (...

    Authors: Kai Ma, Qifeng Wang, Tao Li, Huiming Liu, Bo Liu, Xitang Jia, Shufeng Li, Junyuan Lang and Mingzhi Zhang
    Citation: Radiation Oncology 2014 9:294
    Content type: Research Published on:

  28. PET/CT scans acquired in the radiotherapy treatment position are typically performed without compensating for respiratory motion. The purpose of this study was to investigate geographic miss of lung tumours du...

    Authors: Jason Callahan, Tomas Kron, Shankar Siva, Nathalie Simoens, Amanda Edgar, Sarah Everitt, Michal E Schneider and Rodney J Hicks
    Citation: Radiation Oncology 2014 9:291
    Content type: Research Published on:

  29. Considering the review by Puspitasari and colleagues, an additional discussion of the endpoints of the Se supplementation studies described would be helpful. In our view, selenium can safely be given to seleni...

    Authors: Ralph Muecke, Oliver Micke, Lutz Schomburg, Klaus Kisters, Jens Buentzel, Jutta Huebner and Jan Kriz
    Citation: Radiation Oncology 2014 9:289
    Content type: Letter to the Editor Published on:

  30. The accuracy of dose calculation is crucial to the quality of treatment planning and, consequently, to the dose delivered to patients undergoing radiation therapy. Current general calculation algorithms such a...

    Authors: Yanqun Zhao, Guohai Qi, Gang Yin, Xianliang Wang, Pei Wang, Jian Li, Mingyong Xiao, Jie Li, Shengwei Kang and Xiongfei Liao
    Citation: Radiation Oncology 2014 9:287
    Content type: Research Published on:

  31. This study was conducted to assess the prognostic value of the number of negative lymph nodes (NLNs) in breast cancer patients with four or more positive lymph nodes after postmastectomy radiotherapy (PMRT).

    Authors: San-Gang Wu, Jia-Yuan Sun, Juan Zhou, Feng-Yan Li, Hao Zhou, Qin Lin, Huan-Xin Lin, Yong Bao and Zhen-Yu He
    Citation: Radiation Oncology 2014 9:284
    Content type: Research Published on:

  32. A handful of studies have reported outcomes with CyberKnife radiosurgery (CKRS) for the treatment of trigeminal neuralgia. However, the follow-up has been short with no minimum follow-up required and have incl...

    Authors: Sana D Karam, Alexander Tai, James W Snider, Shilpa Bhatia, Edward J Bedrick, Abdul Rashid, Ann Jay, Christopher Kalhorn, Nathan Nair, K William Harter, Sean P Collins and Walter Jean
    Citation: Radiation Oncology 2014 9:257
    Content type: Research Published on:

  33. To investigate a prognostic role of gross tumor volume (GTV) changes on survival outcomes following concurrent chemoradiotherapy (CCRT) in stage III non-small-cell lung cancer (NSCLC) patients.

    Authors: Tae Ryool Koo, Sung Ho Moon, Yu Jin Lim, Ja Young Kim, Yeonjoo Kim, Tae Hyun Kim, Kwan Ho Cho, Ji-Youn Han, Young Joo Lee, Tak Yun, Heung Tae Kim and Jin Soo Lee
    Citation: Radiation Oncology 2014 9:283
    Content type: Research Published on:

  34. To assess the impact of incremental modifications of treatment planning and delivery technique, as well as patient anatomical factors, on late gastrointestinal toxicity using data from the TROG 03.04 RADAR pro...

    Authors: Noorazrul Yahya, Martin A Ebert, Max Bulsara, Annette Haworth, Rachel Kearvell, Kerwyn Foo, Angel Kennedy, Sharon Richardson, Michele Krawiec, David J Joseph and Jim W Denham
    Citation: Radiation Oncology 2014 9:282
    Content type: Research Published on:

  35. The purpose of this study was to evaluate the brachial plexus (BP) dose of postmastectomy radiotherapy (PMRT) to the ipsilateral supraclavicular (ISCL) area, and report the characteristics of radiation-induced...

    Authors: San-Gang Wu, Si-Juan Huang, Juan Zhou, Jia-Yuan Sun, Han Guo, Feng-Yan Li, Qin Lin, Huan-Xin Lin and Zhen-Yu He
    Citation: Radiation Oncology 2014 9:292
    Content type: Research Published on:

  36. It has been long recognized that cranial irradiation used for the treatment of primary and metastatic brain tumor often causes neurological side-effects such as intellectual impairment, memory loss and dementi...

    Authors: Liyuan Zhang, Kun Li, Rui Sun, Yuan Zhang, JianFeng Ji, Peigeng Huang, Hongying Yang and Ye Tian
    Citation: Radiation Oncology 2014 9:281
    Content type: Research Published on:

  37. Proctitis after radiation therapy for prostate cancer remains an ongoing clinical challenge and critical quality of life issue. SBRT could minimize rectal toxicity by reducing the volume of rectum receiving hi...

    Authors: Daniel Y Joh, Leonard N Chen, Gerald Porter, Aditi Bhagat, Sumit Sood, Joy S Kim, Rudy Moures, Thomas Yung, Siyuan Lei, Brian T Collins, Andrew W Ju, Simeng Suy, John Carroll, John H Lynch, Anatoly Dritschilo and Sean P Collins
    Citation: Radiation Oncology 2014 9:277
    Content type: Research Published on:

  38. Limiting radiation dose to the larynx can diminish effects of laryngeal dysfunction. However, no clear guidelines exist for defining the larynx and its substructures consistently on cross-sectional imaging. Th...

    Authors: Mehee Choi, Tamer Refaat, Malisa S Lester, Ian Bacchus, Alfred W Rademaker and Bharat B Mittal
    Citation: Radiation Oncology 2014 9:285
    Content type: Research Published on:

  39. To evaluate the feasibility and efficacy of simultaneous integrated boost intensity-modulated radiation therapy (SIB-IMRT) in patients with limited-disease small-cell lung cancer (LD-SCLC).

    Authors: Dan Han, Qin Qin, Shaoyu Hao, Wei Huang, Yumei Wei, Zicheng Zhang, Zhongtang Wang and Baosheng Li
    Citation: Radiation Oncology 2014 9:280
    Content type: Study protocol Published on:

  40. This study was conducted to investigate the local effects and toxicity of accelerated hyperfractionated intensity-modulated radiotherapy for recurrent/unresectable rectal cancer in patients with previous pelvi...

    Authors: Gang Cai, Ji Zhu, Weigang Hu and Zhen Zhang
    Citation: Radiation Oncology 2014 9:278
    Content type: Research Published on:

  41. In pulsed-dose rate prostate brachytherapy the dose is delivered during 48 hours after implantation, making the treatment sensitive to oedematic effects possibly affecting dose delivery. The aim was to study c...

    Authors: Anna M Dinkla, Bradley R Pieters, Kees Koedooder, Niek van Wieringen, Rob van der Laarse and Arjan Bel
    Citation: Radiation Oncology 2014 9:272
    Content type: Research Published on:

  42. There are various subgroups of patients with metastatic prostate cancer: polymetastatic, oligometastatic, or oligo-recurrent cancers whose progression follows different courses and for whom there are different...

    Authors: Antonio José Conde Moreno, Carlos Ferrer Albiach, Rodrigo Muelas Soria, Verónica González Vidal, Raquel García Gómez and María Albert Antequera
    Citation: Radiation Oncology 2014 9:258
    Content type: Review Published on:

    The Erratum to this article has been published in Radiation Oncology 2015 10:154

  43. Radiation delivery for malignant brain tumors is gradually becoming more precise. Particularly the possibilities of sparing adjacent normal structures such as the hippocampus are increasing. To determine its r...

    Authors: Raphael Bodensohn, Matthias Söhn, Ute Ganswindt, Gabriele Schupp, Silke B Nachbichler, Oliver Schnell, Claus Belka and Maximilian Niyazi
    Citation: Radiation Oncology 2014 9:276
    Content type: Research Published on:

  44. In the last few years, hypofractionated external beam radiotherapy has gained increasing popularity for prostate cancer treatment, since sufficient evidence exists that prostate cancer has a low α/β ratio, low...

    Authors: Nina-Sophie Hegemann, Matthias Guckenberger, Claus Belka, Ute Ganswindt, Farkhad Manapov and Minglun Li
    Citation: Radiation Oncology 2014 9:275
    Content type: Review Published on:

  45. It is expected that physical dose deposition properties render charged particle dose distributions sensitive to targeting uncertainties. Purpose of this work was to investigate the robustness of scanned-beam p...

    Authors: Filippo Ammazzalorso, Urszula Jelen, Rita Engenhart-Cabillic and Wolfgang Schlegel
    Citation: Radiation Oncology 2014 9:279
    Content type: Research Published on:

  46. To evaluate the clinical features, treatment results, prognostic factors and late toxicities of nasopharyngeal carcinoma in children and adolescents.

    Authors: Weixin Liu, Yuan Tang, Li Gao, Xiaodong Huang, Jingwei Luo, Shiping Zhang, Kai Wang, Yuan Qu, Jianping Xiao, Guozhen Xu and Junlin Yi
    Citation: Radiation Oncology 2014 9:274
    Content type: Research Published on:

  47. Consensus-based approaches provide an alternative to evidence-based decision making, especially in situations where high-level evidence is limited. Our aim was to demonstrate a novel source of information, obj...

    Authors: Paul Martin Putora, Cedric M Panje, Alexandros Papachristofilou, Alan Dal Pra, Thomas Hundsberger and Ludwig Plasswilm
    Citation: Radiation Oncology 2014 9:270
    Content type: Methodology Published on:

  48. Radiation to the neck has long been associated with an elevated risk of hypothyroidism development. The goal of the present work is to define dosimetric predictors of hypothyroidism in oropharyngeal cancer (OP...

    Authors: Arthur Chyan, Josephine Chen, Erin Shugard, Louise Lambert, Jeanne M Quivey and Sue S Yom
    Citation: Radiation Oncology 2014 9:269
    Content type: Research Published on:

  49. The aim of this study is to evaluate the ability of transit dosimetry using commercial treatment planning system (TPS) and an electronic portal imaging device (EPID) with simple calibration method to verify th...

    Authors: Tae Seong Baek, Eun Ji Chung, Jaeman Son and Myonggeun Yoon
    Citation: Radiation Oncology 2014 9:273
    Content type: Research Published on:

  50. The aim of this study was to analyse the reasons for not starting or for early of radiotherapy at the Radiation Oncology Department.

    Authors: Meritxell Arenas, Sebastià Sabater, Marina Gascón, Ivan Henríquez, M José Bueno, Àngels Rius, Àngels Rovirosa, David Gómez, Anna Lafuerza, Albert Biete and Jordi Colomer
    Citation: Radiation Oncology 2014 9:260
    Content type: Research Published on:
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