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  1. In order to locate an arteriovenous malformation, typically, a digital subtraction angiography (DSA) is carried out. To use the DSA for target definition an accurate image registration between CT and DSA is re...

    Authors: Daniel Schmidhalter, Dominik Henzen, Evelyn Herrmann, Werner Volken, Paul-Henry Mackeprang, Ekin Ermis, Hossein Hemmatazad, Jonas Honegger, Benjamin Haas, Michael K. Fix and Peter Manser
    Citation: Radiation Oncology 2019 14:217
  2. This study was designed to explore whether an intensified chemoradiotherapy (CRT) led to a better clinical outcome in locally advanced rectal cancer.

    Authors: Jingwen Wang, Yun Guan, Weilie Gu, Senxiang Yan, Juying Zhou, Dan Huang, Tong Tong, Chao Li, Sanjun Cai, Zhen Zhang and Ji Zhu
    Citation: Radiation Oncology 2019 14:215
  3. Treatment options for recurrent head and neck tumours in the previously irradiated area are limited, including re-irradiation due to radioresistance of the recurrent tumour and previous dose received by surrou...

    Authors: Vesna Todorovic, Ajda Prevc, Martina Niksic Zakelj, Monika Savarin, Andreja Brozic, Blaz Groselj, Primoz Strojan, Maja Cemazar and Gregor Sersa
    Citation: Radiation Oncology 2019 14:214
  4. Accurate and standardized descriptions of organs at risk (OARs) are essential in radiation therapy for treatment planning and evaluation. Traditionally, physicians have contoured patient images manually, which...

    Authors: Sang Hee Ahn, Adam Unjin Yeo, Kwang Hyeon Kim, Chankyu Kim, Youngmoon Goh, Shinhaeng Cho, Se Byeong Lee, Young Kyung Lim, Haksoo Kim, Dongho Shin, Taeyoon Kim, Tae Hyun Kim, Sang Hee Youn, Eun Sang Oh and Jong Hwi Jeong
    Citation: Radiation Oncology 2019 14:213
  5. Radiotherapy-induced lymphopenia may be limiting the success of therapy and could also negatively affect the ability of immune system in mediating the bystander (BE) and abscopal effects (AE). A novel SBRT-bas...

    Authors: Slavisa Tubin, Mohammad K. Khan, Gerardo Salerno, Waleed F. Mourad, Weisi Yan and Branislav Jeremic
    Citation: Radiation Oncology 2019 14:212
  6. To report dosimetry and early adverse effects, aesthetic, and patient-reported outcomes of a prospective study of 3-fraction pencil-beam scanning (PBS) proton accelerated partial irradiation (APBI).

    Authors: Robert W. Mutter, Krishan R. Jethwa, Karthik Gonuguntla, Nicholas B. Remmes, Thomas J. Whitaker, Tina J. Hieken, Kathryn J. Ruddy, Lisa A. McGee, Kimberly S. Corbin and Sean S. Park
    Citation: Radiation Oncology 2019 14:211
  7. Small cell carcinoma of the esophagus (SCCE) is characterized by its progressive feature and poor prognosis. There is no consensus on a standard therapeutic modality for SCCE. In this study, we aimed to charac...

    Authors: Baoqing Chen, Han Yang, Huali Ma, Qiaoqiao Li, Bo Qiu, Yonghong Hu and Yujia Zhu
    Citation: Radiation Oncology 2019 14:210
  8. Severe complications, such as eye damage and dysfunciton of salivary glands, have been reported after radiotherapy among patients with head and neck cancer. Complications such as visual impairment have also be...

    Authors: Soichi Sugiyama, Kuniaki Katsui, Yuki Tominaga, Takahiro Waki, Norihisa Katayama, Hidenobu Matsuzaki, Shin Kariya, Masahiro Kuroda, Kazunori Nishizaki and Susumu Kanazawa
    Citation: Radiation Oncology 2019 14:209
  9. Despite increasing clinical data suggest that internal mammary node (IMN) irradiation would improve local-regional control and overall survival in breast cancer, its role remains controversial due to increased...

    Authors: Yujie Wang, Weixiang Qi, Haoping Xu, Miao Zhang, Yimin Han, Jiayi Chen and Cheng Xu
    Citation: Radiation Oncology 2019 14:208
  10. The purpose of this study was to compare carbon-ion (C-ion), proton and photon radiotherapy (RT) plans with regard to dose reduction of the gastrointestinal (GI) tract by using a greater omentum spacer (GO spa...

    Authors: Masayoshi Yamada, Hiraku Sato, Yoshiro Ieko, Yuya Miyasaka, Takayuki Kanai, Natsuko Yano, Takashi Ono, Hiroko Akamatsu, Mayumi Harada, Mayumi Ichikawa, Yasushi Teranishi, Yasuhiro Kikuchi and Kenji Nemoto
    Citation: Radiation Oncology 2019 14:207
  11. To evaluate the short-term outcomes in terms of tumor control and toxicity of patients with skull base or cervical spine chordoma and chondrosarcoma treated with intensity-modulated proton or carbon-ion radiat...

    Authors: Xiyin Guan, Jing Gao, Jiyi Hu, Weixu Hu, Jing Yang, Xianxin Qiu, Chaosu Hu, Lin Kong and Jiade J. Lu
    Citation: Radiation Oncology 2019 14:206
  12. Some patients experience oligo-progression during androgen receptor targeted therapy (ARTT) treatments. This progression might not indicate a real systemic drug resistance, but a selective monoclonal resistanc...

    Authors: Maurizio Valeriani, Luca Marinelli, Serena Macrini, Chiara Reverberi, Anna Maria Aschelter, Vitaliana De Sanctis, Paolo Marchetti, Lidia Tronnolone and Mattia Falchetto Osti
    Citation: Radiation Oncology 2019 14:205
  13. Breast cancer (BC) radiotherapy (RT) can induce cardiotoxicity, with adverse events often observed many years after BC RT. Subclinical left ventricular (LV) dysfunction can be detected early after BC RT with g...

    Authors: Valentin Walker, Olivier Lairez, Olivier Fondard, Atul Pathak, Baptiste Pinel, Christian Chevelle, Denis Franck, Gaëlle Jimenez, Jérémy Camilleri, Loïc Panh, David Broggio, Sylvie Derreumaux, Marie-Odile Bernier, Dominique Laurier, Jean Ferrières and Sophie Jacob
    Citation: Radiation Oncology 2019 14:204
  14. To determine the prognostic effect of adjuvant radiation and clinicopathological variables in surgically treated patients with small cell carcinoma of the cervix (SCCC).

    Authors: Ting Shen, Yan-hui Jiang, Yao-yao Zou, Fang-fang Qiu, Xing-sheng Qiu and Kai-yun You
    Citation: Radiation Oncology 2019 14:203
  15. The objective of this investigation is to evaluate the outcomes and toxicity of carbon-ion re-irradiation (CIR) in patients with rare head and neck cancers (HNC). There is a paucity of data regarding treatment...

    Authors: Thomas Held, Paul Windisch, Sati Akbaba, Kristin Lang, Benjamin Farnia, Jakob Liermann, Denise Bernhardt, Peter Plinkert, Christian Freudlsperger, Stefan Rieken, Klaus Herfarth, Jürgen Debus and Sebastian Adeberg
    Citation: Radiation Oncology 2019 14:202
  16. This retrospective German and Italian multicenter analysis aimed to compare the role of normofractionated stereotactic radiotherapy (nFSRT) to CyberKnife-based hypofractionated stereotactic radiotherapy (CK-hF...

    Authors: Conti Alfredo, Senger Carolin, Acker Güliz, Kluge Anne, Pontoriero Antonio, Cacciola Alberto, Pergolizzi Stefano, Germanò Antonino, Badakhshi Harun, Kufeld Markus, Meinert Franziska, Nguyen Phuong, Loebel Franziska, Vajkoczy Peter, Budach Volker and Kaul David
    Citation: Radiation Oncology 2019 14:201

    The Correction to this article has been published in Radiation Oncology 2020 15:279

  17. The purpose of this study was to evaluate the outcomes of elderly patients (aged ≥75 years) with newly diagnosed glioblastoma (GBM), who were treated with hypofractionated radiotherapy comprising 45 Gy in 15 f...

    Authors: Makoto Ohno, Yasuji Miyakita, Masamichi Takahashi, Hiroshi Igaki, Yuko Matsushita, Koichi Ichimura and Yoshitaka Narita
    Citation: Radiation Oncology 2019 14:200
  18. Postradiogenic wound healing disorders are an important clinical problem. While a variety of treatment modalities are available, there is no strategy to objectively judge treatment success. The aim of this stu...

    Authors: Steffen Auerswald, Stephan Schreml, Robert Meier, Alexandra Blancke Soares, Maximilian Niyazi, Sebastian Marschner, Claus Belka, Martin Canis and Frank Haubner
    Citation: Radiation Oncology 2019 14:199
  19. Adjuvant (ART) and salvage radiotherapy (SRT) are two common concepts to enhance biochemical relapse free survival (BCRFS) in patients with prostate cancer (PC). We analyzed differences in outcome between ART ...

    Authors: Marco M. E. Vogel, Kerstin A. Kessel, Kilian Schiller, Michal Devecka, Jürgen E. Gschwend, Wilko Weichert, Jan J. Wilkens and Stephanie E. Combs
    Citation: Radiation Oncology 2019 14:198
  20. The appropriate timing of radiotherapy (RT) for patients after radical prostatectomy (RP) with adverse pathological features (APFs) remains controversial. This systematic review was conducted to compare the ef...

    Authors: Ronggui Tao, Jindong Dai, Yunjin Bai, Jiyu Yang, Guangxi Sun, Xingming Zhang, Jinge Zhao, Hao Zeng and Pengfei Shen
    Citation: Radiation Oncology 2019 14:197
  21. To compare irradiation dose to the second and third portions of duodenum (Duo2 and Duo3) with a new refined and old delineation method of para-aortic region for patients with locally advanced cervical cancer (...

    Authors: Bo Yang, Xiaoliang Liu, Ke Hu, Jie Qiu, Fuquan Zhang, Xiaorong Hou, Junfang Yan, Qingyu Meng, Weiping Wang, Lang Yu and Yijun Wang
    Citation: Radiation Oncology 2019 14:196
  22. The optimal treatment for elderly patients with early-stage non-small cell lung cancer (NSCLC) remains inconclusive. Previous studies have shown that stereotactic body radiotherapy (SBRT) provides encouraging ...

    Authors: Baiqiang Dong, Jin Wang, Xuan Zhu, Yuanyuan Chen, Yujin Xu, Kainan Shao, Lei Zheng, Hangjie Ying, Ming Chen and Jianping Cao
    Citation: Radiation Oncology 2019 14:195
  23. Stereotactic body radiation therapy (SBRT) was found effective in treating laryngeal cancer with only five treatment fractions by a recent clinical trial (NCT01984502, ClinicalTrials.gov). Nevertheless, this t...

    Authors: You Zhang, Tsuicheng Chiu, Jeffrey Dubas, Zhen Tian, Pam Lee, Xuejun Gu, Yulong Yan, David Sher, Robert Timmerman and Bo Zhao
    Citation: Radiation Oncology 2019 14:193
  24. To determine the biological correlation between apparent diffusion coefficient (ADC) values and Sirtuin1 (SIRT1) levels of tumour tissues in patients with esophageal carcinoma (EC), and to ascertain the treatm...

    Authors: Ying Chen, Tieming Xie, Zhimin Ye, Fangzheng Wang, Dan Long, Mingxiang Jiang, Jun Fang, Qingren Lin, Kai Li, Zhun Wang and Zhenfu Fu
    Citation: Radiation Oncology 2019 14:192
  25. Re-irradiation (re-RT) has the active effect of relieving clinical symptoms and prolonging the survival of patients with recurrent esophageal squamous cell carcinoma (ESCC). However, the optimal re-RT dose is ...

    Authors: Xiujuan Xu, Zhongming Wang, Shunian Jiang, Yuping Shang and Yan Wu
    Citation: Radiation Oncology 2019 14:191
  26. We aimed to ascertain population-based practice patterns and survival outcomes of postoperative radiotherapy following breast conserving-surgery (BCS) in elderly women (aged ≥65 years) with early-stage pure mu...

    Authors: San-Gang Wu, Feng-Yan Li, Jun Wang, Chen-Lu Lian, Juan Zhou and Zhen-Yu He
    Citation: Radiation Oncology 2019 14:190
  27. Patients treated with radiotherapy for head and neck (H&N) cancer often experience anatomical changes. The potential compromises to Planning Target Volume (PTV) coverage or Organ at Risk (OAR) sparing has prom...

    Authors: Louise Belshaw, Christina E. Agnew, Denise M. Irvine, Keith P. Rooney and Conor K. McGarry
    Citation: Radiation Oncology 2019 14:189
  28. Thoracic and head and neck cancer radiation therapy (RT) can cause damage to nearby healthy organs such as the esophagus, causing acute radiation-induced esophageal damage (ARIED). A non-invasive method to det...

    Authors: Pouya Jelvehgaran, Jeffrey D. Steinberg, Artem Khmelinskii, Gerben Borst, Ji-Ying Song, Niels de Wit, Daniel M. de Bruin and Marcel van Herk
    Citation: Radiation Oncology 2019 14:188
  29. To determine if the performance of a knowledge based RapidPlan (RP) planning model could be improved with an iterative learning process, i.e. if plans generated by an RP model could be used as new input to re-...

    Authors: A. Fogliata, L. Cozzi, G. Reggiori, A. Stravato, F. Lobefalo, C. Franzese, D. Franceschini, S. Tomatis and M. Scorsetti
    Citation: Radiation Oncology 2019 14:187
  30. Tumor motion may compromise the accuracy of liver stereotactic radiotherapy. In order to carry out a precise planning, estimating liver tumor motion during radiotherapy has received a lot of attention. Previou...

    Authors: Wu-zhou Li, Zhi-wen Liang, Yi Cao, Ting-ting Cao, Hong Quan, Zhi-yong Yang, Qin Li and Zhi-tao Dai
    Citation: Radiation Oncology 2019 14:185
  31. Stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT) are well established local treatment approaches in several cancer settings. Although SBRT is still under investigation for spinal metas...

    Authors: Niccolò Giaj-Levra, Maximilian Niyazi, Vanessa Figlia, Giuseppe Napoli, Rosario Mazzola, Luca Nicosia, Stefanie Corradini, Ruggero Ruggieri, Giuseppe Minniti and Filippo Alongi
    Citation: Radiation Oncology 2019 14:184
  32. To quantify the effects of the Bragg peak degradation due to lung tissue on treatment plans of lung cancer patients with spot scanning proton therapy and to give a conservative approximation of these effects.

    Authors: Kilian-Simon Baumann, Veronika Flatten, Uli Weber, Stefan Lautenschläger, Fabian Eberle, Klemens Zink and Rita Engenhart-Cabillic
    Citation: Radiation Oncology 2019 14:183

    The Correction to this article has been published in Radiation Oncology 2020 15:29

  33. Patients with N3 stage nasopharyngeal carcinoma (NPC) are at high risk for treatment failure. This study aims to assess the efficacy of maintenance chemotherapy (MC) using S-1 (MC-S1), a novel oral fluoropyrim...

    Authors: Jingfeng Zong, Hanchuan Xu, Bijuan Chen, Qiaojuan Guo, Yun Xu, Chuanben Chen, Youliang Weng, Wei Zheng, Jianji Pan and Shaojun Lin
    Citation: Radiation Oncology 2019 14:182
  34. We aimed to identify the risk factors and provide a nomogram for the prediction of radiotherapy-related esophageal fistula in patients with esophageal cancer (EC) using a case-control study.

    Authors: Yiyue Xu, Linlin Wang, Bo He, Wanlong Li, Qiang Wen, Shijiang Wang, Xindong Sun, Xue Meng and Jinming Yu
    Citation: Radiation Oncology 2019 14:181
  35. This study aimed to compare the clinical outcomes of stereotactic ablative radiotherapy (SABR) and conventionally fractionated radiotherapy (CFRT) in hepatocellular carcinoma (HCC) patients with portal vein in...

    Authors: Jen-Fu Yang, Cheng-Hsiang Lo, Meei-Shyuan Lee, Chun-Shu Lin, Yang-Hong Dai, Po-Chien Shen, Hsing-Lung Chao and Wen-Yen Huang
    Citation: Radiation Oncology 2019 14:180
  36. To assess late toxicity, quality of life and oncological outcome after consolidative whole abdominal radiotherapy (WART) following cytoreductive surgery and carboplatin/paclitaxel chemotherapy in high risk pat...

    Authors: Nathalie Arians, Meinhard Kieser, Laura Benner, Nathalie Rochet, Lars Schröder, Sonja Katayama, Klaus Herfarth, Kai Schubert, Andreas Schneeweiss, Christof Sohn, Katja Lindel and Jürgen Debus
    Citation: Radiation Oncology 2019 14:179
  37. Radiation Therapy Oncology Group (RTOG) 94–05 has demonstrated that higher dose radiation didn’t improve outcome of patients with esophageal cancer (EC). However, several retrospective studies showed that a hi...

    Authors: He-San Luo, He-Cheng Huang and Lian-Xing Lin
    Citation: Radiation Oncology 2019 14:178
  38. There is no general consensus on the optimal treatment for prostate cancer (PC) patients with intrapelvic nodal oligorecurrences after radical prostatectomy. Besides androgen deprivation therapy (ADT) as stand...

    Authors: Cedric Panje, Thomas Zilli, Alan Dal Pra, Winfried Arnold, Kathrin Brouwer, Helena I. Garcia Schüler, Silvia Gomez, Fernanda Herrera, Kaouthar Khanfir, Alexandros Papachristofilou, Gianfranco Pesce, Christiane Reuter, Hansjörg Vees, Daniel Zwahlen and Paul Martin Putora
    Citation: Radiation Oncology 2019 14:177
  39. To assess the comparative efficacy and safety of elective nodal irradiation (ENI) and involved-field irradiation (IFI) in patients with esophageal cancer (EC) receiving neoadjuvant chemoradiotherapy plus surge...

    Authors: Tingting Liu, Silu Ding, Jun Dang, Hui Wang, Jun Chen and Guang Li
    Citation: Radiation Oncology 2019 14:176
  40. We evaluated the long-term outcomes and late toxicity of conventional fractionated (CF) and hypofractionated (HF) postmastectomy radiotherapy (PMRT) in terms of locoregional recurrence-free survival (LRRFS), d...

    Authors: Imjai Chitapanarux, Pitchayaponne Klunklin, Attapol Pinitpatcharalert, Patumrat Sripan, Ekkasit Tharavichitkul, Wannapha Nobnop, Wimrak Onchan, Somvilai Chakrabandhu, Bongkot Jia-Mahasap, Juntima Euathrongchit, Yutthaphan Wannasopha and Tanop Srisuwan
    Citation: Radiation Oncology 2019 14:175
  41. This study aimed to evaluate the clinical and dosimetric factors predictive of acute anal toxicity (AAT) after radiotherapy in prostate cancer (PCa) patients with or without hemorrhoids.

    Authors: Xingsi Peng, Sha Zhou, Shiliang Liu, Jibin Li, Sijuan Huang, Xiaobo Jiang, Maosheng Lin, Shaomin Huang, Chengguang Lin, Chaonan Qian, Mengzhong Liu and Liru He
    Citation: Radiation Oncology 2019 14:174
  42. Ultrasound (US) imaging has been proved as an excellent diagnostic tool in gynecology and, due to its wide availability and limited cost, is under intense investigation as base for dose adaptation in cervical ...

    Authors: Mario Federico, Carmen Rosa Hernandez-Socorro, Ivone Ribeiro, Jesus Gonzalez Martin, Maria Dolores Rey-Baltar Oramas, Marta Lloret Saez-Bravo and Pedro Carlos Lara Jimenez
    Citation: Radiation Oncology 2019 14:173
  43. Vendor-independent Monte Carlo (MC) dose calculation (IDC) for patient-specific quality assurance of multi-leaf collimator (MLC) based CyberKnife treatments is used to benchmark and validate the commercial MC ...

    Authors: P.-H. Mackeprang, D. Vuong, W. Volken, D. Henzen, D. Schmidhalter, M. Malthaner, S. Mueller, D. Frei, W. Kilby, D. M. Aebersold, M. K. Fix and P. Manser
    Citation: Radiation Oncology 2019 14:172
  44. Prophylactic cranial irradiation (PCI) is indicated for limited-stage small cell lung cancer (LS-SCLC) with good response to chemoradiotherapy (CRT). However, brain metastasis (BM) developed in LS-SCLC before ...

    Authors: Xiao Chu, Shuyan Li, Bingqing Xia, Li Chu, Xi Yang, Jianjiao Ni, Liqing Zou, Yida Li, Congying Xie, Jie Lin and Zhengfei Zhu
    Citation: Radiation Oncology 2019 14:171
  45. Pathogenesis of brain metastases/meningeal cancer and the emotional and neurological outcomes are not yet well understood. The hypothesis of our study is that patients with leptomeningeal cancer show volumetri...

    Authors: Michael Mayinger, Antonia Reibelt, Kai Joachim Borm, Johannes Ettl, Jan J. Wilkens, Stephanie Elisabeth Combs, Markus Oechsner and Marciana Nona Duma
    Citation: Radiation Oncology 2019 14:170
  46. Leptomeningeal metastasis (LM) is a devastating and terminal complication of advanced non-small-cell lung cancer (NSCLC), especially in patients harboring epidermal growth factor receptor (EGFR) mutations. The...

    Authors: Weiwei Yan, Yang Liu, Ji Li, Anqin Han, Li Kong, Jinming Yu and Hui Zhu
    Citation: Radiation Oncology 2019 14:168
  47. The purpose of this study was to assess the feasibility, efficacy and toxicity of fiducial marker implantation and tracking in CyberKnife® stereotactic radiation therapy (SBRT) applied to extracranial locations.

    Authors: Nathaniel Scher, Marc Bollet, Gauthier Bouilhol, Remi Tannouri, Imane Khemiri, Aurelie Vouillaume, Noura Sellami, Rie Von Eyben, Jean-Michel Vannetzel, Ilan Darmon, Luc Rotenberg, Hanah Lamallem, Olivier Bauduceau, Denis Foster and Alain Toledano
    Citation: Radiation Oncology 2019 14:167

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