Stone HB, Moulder JE, Coleman CN, Ang KK, Anscher MS, Barcellos-Hoff MH, Dynan WS, Fike JR, Grdina DJ, Greenberger JS, Hauer-Jensen M, Hill RP, Kolesnick RN, Macvittie TJ, Marks C, McBride WH, Metting N, Pellmar T, Purucker M, Robbins ME, Schiestl RH, Seed TM, Tomaszewski JE, Travis EL, Wallner PE, Wolpert M, Zaharevitz D: Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res 2004,162(6):711-28. 10.1667/RR3276
Article
CAS
PubMed
Google Scholar
Coleman CN: Modulating the Radiation Response. Oncologist 1996,1(4):227-231.
CAS
PubMed
Google Scholar
Sonntag Cv: Protection, sensitization and the oxygen effect. In The Chemical Basis of Radiation Biology. Taylor and Francis: London; 1987:295-352.
Google Scholar
Vos O, Budke L, Grant GA: In vitro evaluation of some latent radioprotective compounds. Int J Radiat Biol Relat Stud Phys Chem Med 1976,30(5):433-48. 10.1080/09553007614551251
Article
CAS
PubMed
Google Scholar
Yuhas JM: Biological factors affecting the radioprotective efficiency of S-2-[2-aminopropylamino] ethylphosphorothioic acid (WR-2721). LD50(3)) doses. Radiat Res 1970,44(3):621-8. 10.2307/3573143
Article
CAS
PubMed
Google Scholar
Hahn SM, Tochner Z, Krishna CM, Glass J, Wilson L, Samuni A, Sprague M, Venzon D, Glatstein E, Mitchell JB, et al.: Tempol, a stable free radical, is a novel murine radiation protector. Cancer Res 1992,52(7):1750-3.
CAS
PubMed
Google Scholar
Mitchell JB, DeGraff W, Kaufman D, Krishna MC, Samuni A, Finkelstein E, Ahn MS, Hahn SM, Gamson J, Russo A: Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol. Arch Biochem Biophys 1991,289(1):62-70. 10.1016/0003-9861(91)90442-L
Article
CAS
PubMed
Google Scholar
Soule BP, Hyodo F, Matsumoto K, Simone NL, Cook JA, Krishna MC, Mitchell JB: The chemistry and biology of nitroxide compounds. Free Radic Biol Med 2007,42(11):1632-50. 10.1016/j.freeradbiomed.2007.02.030
Article
PubMed Central
CAS
PubMed
Google Scholar
Rochester Uo: Curcumin derivatives and their use as radioprotectors. 2008.
Google Scholar
Ghosh SP, Kulkarni S, Hieber K, Toles R, Romanyukha L, Kao TC, Hauer-Jensen M, Kumar KS: Gamma-tocotrienol, a tocol antioxidant as a potent radioprotector. Int J Radiat Biol 2009,85(7):598-606. 10.1080/09553000902985128
Article
CAS
PubMed
Google Scholar
Epperly M, Jin S, Nie S, Cao S, Zhang X, Franicola D, Wang H, Fink MP, Greenberger JS: Ethyl pyruvate, a potentially effective mitigator of damage after total-body irradiation. Radiat Res 2007,168(5):552-9. 10.1667/RR1009.1
Article
CAS
PubMed
Google Scholar
Buc-Calderon P, Defresne MP, Barvais C, Roberfroid M: N-acyl dehydroalanines protect from radiation toxicity and inhibit radiation carcinogenesis in mice. Carcinogenesis 1989,10(9):1641-4. 10.1093/carcin/10.9.1641
Article
CAS
PubMed
Google Scholar
Murley JS, Kataoka Y, Baker KL, Diamond AM, Morgan WF, Grdina DJ: Manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by the free thiol form of amifostine and tumor necrosis factor alpha. Radiat Res 2007,167(4):465-74. 10.1667/RR0758.1
Article
CAS
PubMed
Google Scholar
Blickenstaff RT, Brandstadter SM, Reddy S, Witt R: Potential radioprotective agents. 1. Homologs of melatonin. J Pharm Sci 1994,83(2):216-8. 10.1002/jps.2600830220
Article
CAS
PubMed
Google Scholar
Dumont F, Le Roux A, Bischoff P: Radiation countermeasure agents: an update. Expert Opin Ther Pat 20(1):73-101. 10.1517/13543770903490429
Davidson W, Ren Q, Kari G, Kashi O, Dicker AP, Rodeck U: Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos. Cell Cycle 2008,7(9):1224-30.
Article
CAS
PubMed
Google Scholar
Arienti KL, Brunmark A, Axe FU, McClure K, Lee A, Blevitt J, Neff DK, Huang L, Crawford S, Pandit CR, Karlsson L, Breitenbucher JG: Checkpoint kinase inhibitors: SAR and radioprotective properties of a series of 2-arylbenzimidazoles. J Med Chem 2005,48(6):1873-85. 10.1021/jm0495935
Article
CAS
PubMed
Google Scholar
Ghosh SP, Perkins MW, Hieber K, Kulkarni S, Kao TC, Reddy EP, Reddy MV, Maniar M, Seed T, Kumar KS: Radiation protection by a new chemical entity, Ex-Rad: efficacy and mechanisms. Radiat Res 2009,171(2):173-9. 10.1667/RR1367.1
Article
CAS
PubMed
Google Scholar
Bonnaud S, Niaudet C, Pottier G, Gaugler MH, Millour J, Barbet J, Sabatier L, Paris F: Sphingosine-1-phosphate protects proliferating endothelial cells from ceramide-induced apoptosis but not from DNA damage-induced mitotic death. Cancer Res 2007,67(4):1803-11. 10.1158/0008-5472.CAN-06-2802
Article
CAS
PubMed
Google Scholar
Osuna S, Swart M, Sola M: On the mechanism of action of fullerene derivatives in superoxide dismutation. Chemistry 3207,16(10):3207-14.
Article
Google Scholar
Nielsen GD, Roursgaard M, Jensen KA, Poulsen SS, Larsen ST: In vivo biology and toxicology of fullerenes and their derivatives. Basic Clin Pharmacol Toxicol 2008,103(3):197-208. 10.1111/j.1742-7843.2008.00266.x
Article
CAS
PubMed
Google Scholar
Dugan LL, Lovett EG, Quick KL, Lotharius J, Lin TT, O'Malley KL: Fullerene-based antioxidants and neurodegenerative disorders. Parkinsonism Relat Disord 2001,7(3):243-246. 10.1016/S1353-8020(00)00064-X
Article
PubMed
Google Scholar
Ryman-Rasmussen JP, Tewksbury EW, Moss OR, Cesta MF, Wong BA, Bonner JC: Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma. Am J Respir Cell Mol Biol 2009,40(3):349-58. 10.1165/rcmb.2008-0276OC
Article
PubMed Central
CAS
PubMed
Google Scholar
Roursgaard M, SS Poulsen, Kepley CL, Hammer M, Nielsen GD, Larsen ST: Polyhydroxylated C60 fullerene (fullerenol) attenuates neutrophilic lung inflammation in mice. Basic Clin Pharmacol Toxicol 2008,103(4):386-8. 10.1111/j.1742-7843.2008.00315.x
Article
CAS
PubMed
Google Scholar
Basso AS, Frenkel D, Quintana FJ, Costa-Pinto FA, Petrovic-Stojkovic S, Puckett L, Monsonego A, Bar-Shir A, Engel Y, Gozin M, Weiner HL: Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis. J Clin Invest 2008,118(4):1532-43. 10.1172/JCI33464
Article
PubMed Central
CAS
PubMed
Google Scholar
Lin HS, Lin TS, Lai RS, D'Rosario T, Luh TY: Fullerenes as a new class of radioprotectors. Int J Radiat Biol 2001,77(2):235-9. 10.1080/095530001750068966
Article
CAS
PubMed
Google Scholar
Trajkovic S, Dobric S, Jacevic V, Dragojevic-Simic V, Milovanovic Z, Dordevic A: Tissue-protective effects of fullerenol C60(OH)24 and amifostine in irradiated rats. Colloids Surf B Biointerfaces 2007,58(1):39-43. 10.1016/j.colsurfb.2007.01.005
Article
CAS
PubMed
Google Scholar
Daroczi B, Kari G, McAleer MF, Wolf JC, Rodeck U, Dicker AP: In vivo radioprotection by the fullerene nanoparticle DF-1 as assessed in a zebrafish model. Clin Cancer Res 2006,12(23):7086-91. 10.1158/1078-0432.CCR-06-0514
Article
CAS
PubMed
Google Scholar
Lucente-Schultz RM, Moore VC, Leonard AD, Price BK, Kosynkin DV, Lu M, Partha R, Conyers JL, Tour JM: Antioxidant single-walled carbon nanotubes. J Am Chem Soc 2009,131(11):3934-41. 10.1021/ja805721p
Article
CAS
PubMed
Google Scholar
Hahn SM, Wilson L, Krishna CM, Liebmann J, DeGraff W, Gamson J, Samuni A, Venzon D, Mitchell JB: Identification of nitroxide radioprotectors. Radiat Res 1992,132(1):87-93. 10.2307/3578338
Article
CAS
PubMed
Google Scholar
Allalunis-Turner MJ, Walden TL, Sawich C Jr: Induction of marrow hypoxia by radioprotective agents. Radiat Res 1989,118(3):581-6. 10.2307/3577415
Article
CAS
PubMed
Google Scholar
Horie M, Fukuhara A, Saito Y, Yoshida Y, Sato H, Ohi H, Obata M, Mikata Y, Yano S, Niki E: Antioxidant action of sugar-pendant C60 fullerenes. Bioorg Med Chem Lett 2009,19(20):5902-4. 10.1016/j.bmcl.2009.08.067
Article
CAS
PubMed
Google Scholar
Lao F, Li W, Han D, Qu Y, Liu Y, Zhao Y, Chen C: Fullerene derivatives protect endothelial cells against NO-induced damage. Nanotechnology 2009,20(22):225103. 10.1088/0957-4484/20/22/225103
Article
PubMed
Google Scholar
Yin JJ, Lao F, Fu PP, Wamer WG, Zhao Y, Wang PC, Qiu Y, Sun B, Xing G, Dong J, Liang XJ, Chen C: The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials 2009,30(4):611-21. 10.1016/j.biomaterials.2008.09.061
Article
CAS
PubMed
Google Scholar
Ali SS, Hardt JI, Dugan LL: SOD activity of carboxyfullerenes predicts their neuroprotective efficacy: a structure-activity study. Nanomedicine 2008, 4: 283-94.
Article
PubMed Central
CAS
PubMed
Google Scholar
Cai X, Hao J, Zhang X, Yu B, Ren J, Luo C, Li Q, Huang Q, Shi X, Li W, Liu J: The polyhydroxylated fullerene derivative C60(OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction. Toxicol Appl Pharmacol 243(1):27-34. 10.1016/j.taap.2009.11.009
Utley JF, Marlowe C, Waddell WJ: Distribution of 35 S-Labeled WR-2721 in Normal and Malignant Tissues of the Mouse. Radiation Research 1976,68(2):284-291. 10.2307/3574479
Article
CAS
PubMed
Google Scholar
Porter AE, Gass M, Muller K, Skepper JN, Midgley P, Welland M: Visualizing the uptake of C60 to the cytoplasm nucleus of human monocyte-derived macrophage cells using energy-filtered transmission electron microscopy electron tomography. Environ Sci Technol 2007,41(8):3012-7. 10.1021/es062541f
Article
CAS
PubMed
Google Scholar
Hall EJ, Giaccia AJ: Radiobiology for the Radiologist. 6th edition. Philadelphia: Lippincott Williams & Wilkins; 2006.
Google Scholar