Calibration and evaluation of the relative biological effectiveness for carbon-ion radiotherapy in a new relative to a clinically applied treatment planning system

Table 1 Parameters of the evaluation plans in WPs

Iso^a	Target shape		Target size^b	Prescription^c				Beam arrangements^d			Dose grid
Iso^a	Cube	Sphere	Target size^b	3.0	3.5	4.0	4.5	Single	Orthogonal	Opposed	2 mm	3 mm
3	√	√	1.0–5.0			√		√	√		√
7	√		4.0–12.0	√	√	√	√	√				√
7	√	√	4.0–12.0			√		√	√	√		√
11	√	√	4.0–12.0			√		√	√	√		√
15	√	√	4.0–12.0			√		√	√	√		√

^aDistances from the surface of WPs to the target centers
^bDimensions of the cube targets or the diameters of the sphere targets (cm), the step size is 2.0 cm
^cPrescribed RBE-weighted doses [Gy (RBE)] in Syngo
^dBeam arrangements are the single beam, two orthogonal beams, and two opposed beams

ISSN: 1748-717X