Optimization of dose distributions of target volumes and organs at risk during stereotactic body radiation therapy for pancreatic cancer with dose-limiting auto-shells

Table 4 Evaluations of dose to OAR

	Group			P-value (ANOVA)	P-value (LSD, 3-shell vs 5-shell)	P-value (LSD, 5-shell vs 7-shell)	P-value (LSD, 3-shell vs 7-shell)
Parameter	3-shell	5-shell	7-shell	P-value (ANOVA)	P-value (LSD, 3-shell vs 5-shell)	P-value (LSD, 5-shell vs 7-shell)	P-value (LSD, 3-shell vs 7-shell)
Intestine (D_max)	21.69 ± 3.13	21.28 ± 3.62	21.17 ± 3.64	0.359	0.286	0.769	0.176
Intestine (D_5cc)	15.50 ± 2.10	15.27 ± 2.51	14.95 ± 2.51	0.011	0.183	0.076	0.003
Stomach (D_max)	22.14 ± 2.12	22.17 ± 1.66	22.12 ± 2.35	0.976	0.897	0.826	0.928
Stomach (D_10cc)	14.32 ± 1.74	14.13 ± 2.13	13.97 ± 2.23	0.064	0.183	0.292	0.020
Duodenum (D_max)	18.23 ± 4.04	18.27 ± 4.11	17.91 ± 4.01	0.274	0.891	0.147	0.187
Duodenum (D_5cc)	10.54 ± 3.50	10.72 ± 3.55	10.71 ± 3.43	0.63	0.395	0.961	0.422
Duodenum (D_10cc)	8.76 ± 3.22	8.81 ± 3.30	8.80 ± 3.20	0.968	0.808	0.953	0.854
Spinal cord (D_max)	7.12 ± 1.20	6.91 ± 1.28	6.63 ± 0.89	0.131	0.374	0.251	0.046
Spinal cord (D_0.35cc)	6.56 ± 1.05	6.36 ± 1.12	6.17 ± 0.75	0.151	0.321	0.328	0.053
Spleen (D_mean)	31.99 ± 11.91	30.70 ± 12.03	30.34 ± 11.38	0.989	0.987	0.890	0.903
Spleen (V₅)	7.47 ± 11.27	5.22 ± 11.88	4.24 ± 11.28	0.851	0.697	0.873	0.584
Spleen (V₁₀)	0.005 ± 5.42	0 ± 5.42	0 ± 5.23	0.037	0.339	1.000	0.012
Spleen (D_50%)	26.60 ± 5.73	26.68 ± 7.66	26.96 ± 5.31	0.903	0.678	0.721	0.954

ISSN: 1748-717X