Hypofractionated irradiation of infra-supraclavicular lymph nodes after axillary dissection in patients with breast cancer post-conservative surgery: impact on late toxicity

Table 3 BED comparison between standard and explored RT schedule [11]

RT schedule	BED tumor control α/β ₄		BED acute effects α/β ₁₀		BED fibrosis α/β _1.7		BED vascular damage α/β _2.5
W.B. = whole breast	W.B.	B.S	W.B.	B.S	W.B.	B.S	W.B.	B.S
B.S. = tumor bed side	W.B.	B.S	W.B.	B.S	W.B.	B.S	W.B.	B.S
60 Gy/30 F/6 W	75	90	60	72	109	131	90	108
(50 Gy + 10 Gy seq.boost)	75	90	60	72	109	131	90	108
52 Gy/20/F/5 W (46 Gy + 6 Gy cc.boost)	72	87	57	66	108	135	88	108
UK START TRIAL A	75	75	55	55	120	120	95	95
41.6 Gy/13 F/5 W	75	75	55	55	120	120	95	95
UK START TRIAL A	68	68	51	51	108	108	86	86
39 Gy/13 F/5 W	68	68	51	51	108	108	86	86

ISSN: 1748-717X