3D-image-guided high-dose-rate intracavitary brachytherapy for salvage treatment of locally persistent nasopharyngeal carcinoma

Table 2 Failure patterns in NPC patients with locally persistent disease

Pt. No.	Sex /Age	AJCC T stage at initial diagnosis	AJCC T stage at relapse	Primary treatment	Second treatment for relapse	Time to relapse (mo)	Relapse site
1	F/47	T3	rT1	IMRT 68 Gy	3D-HDR-ICBT	14	Parapharyngeal space
					16 Gy
2	M/33	T4	rT2a	IMRT 68 Gy	3D-HDR-ICBT	16	Skull base
2	M/33	T4	rT2a	IMRT 68 Gy	12 Gy	16	Skull base
3	F/59	T2	rT1	IMRT 68 Gy	3D-HDR-ICBT	34	Bone
3	F/59	T2	rT1	IMRT 68 Gy	12 Gy	34	Bone
4	F/44	T1	rT1	IMRT 68 Gy	3D-HDR-ICBT	27	Bone
4	F/44	T1	rT1	IMRT 68 Gy	12 Gy	27	Bone
5	M/57	T1	rT1	IMRT 68 Gy	3D-HDR-ICBT	19	Neck nodal
5	M/57	T1	rT1	IMRT 68 Gy	16 Gy	19	Neck nodal
6	F/62	T1	rT1	IMRT 68 Gy	3D-HDR-ICBT	24	Liver
6	F/62	T1	rT1	IMRT 68 Gy	12 Gy	24	Liver
7	F/42	T2	rT2a	IMRT 68 Gy	3D-HDR-ICBT	17	Lung(29 months died)
7	F/42	T2	rT2a	IMRT 68 Gy	20 Gy	17	Lung(29 months died)

AJCC: American Joint Committee on Cancer staging system (2002); Pt. No.:patient number; F/M: female, male; IMRT: Intensity-modulated Radiotherapy; Chemo-IMRT: concurrent IMRT and chemotherapy; 3D-HDR-ICBT: Three-Dimensional CT-based high-Dose-Rate Intracavitary Brachytherapy. Time to relapse (mo): After second treatment(3D-HDR-ICBT) for relapse, the time, patients developed local recurrence and/or distant metastasis, is defined as Time to relapse (mo).

ISSN: 1748-717X