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Table 2 Univariate analysis of patient characteristics associated with radiation-induced liver Damage (RILD)

From: Prognostic analysis of radiation-induced liver damage following carbon-ion radiotherapy for hepatocellular carcinoma

Parameters

Patients with RILD

Patients without RILD

p-value

Age

  

0.759

  <76 years

6

47

 

  ≥76

5

50

 

Sex

  

0.172

 Male

10

67

 

 Female

1

30

 

ECOG PS

  

1.00

 0

9

77

 

 1 or 2

2

20

 

Number of lesions irradiated simultaneously

  

0.057

 1

7

85

 

  ≥2

4

12

 

Etiology

  

0.153

 HCV

2

22

 

 Alcohol

6

15

 

 NASH

2

21

 

 HBV

1

8

 

 Others

0

31

 

Tumor localization

  

0.200

 Central

6

33

 

 Peripheral

5

64

 

Tumor diameter

  

0.347

 <40 mm

3

43

 

 ≥40 mm

8

54

 

Child–Pugh score

  

0.009

 Class A

7

91

 

 Class B

4

6

 

ALBI grade

  

0.011

 Grade 1

2

58

 

 Grade 2

9

39

 
  1. ECOG PS Eastern Cooperative Oncology Group performance status, HCV hepatitis C virus, NASH nonalcoholic steatohepatitis, HBV Hepatitis B virus, ALBI albumin–bilirubin