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Table 2 Univariate and multivariate analyses affecting overall survival

From: Survival analysis after stereotactic ablative radiotherapy for early stage non-small cell lung cancer: a single-institution cohort study

Variables

Univariate analysis

Multivariate analysis

HR

95% CI

P value

HR

95% CI

P value

Age

0.99

0.97–1.01

0.399

   

≥ 78

1

  

< 78

1.77

1.10–2.84

0.018

Sex

      

Female

1

     

Male

1.66

1.11–2.47

0.013

1.51

1.01–2.28

0.047

AACCI

      

≤ 5

1

     

≥ 6

1.67

1.13–2.47

0.010

1.56

1.06–2.31

0.026

FEV1%

      

≥ 50

1

  

< 50

1.06

0.72–1.58

0.762

Histology

      

Unproven

1

  

Proven

1.16

0.79–1.69

0.457

Adeno

1.12

0.69–1.81

0.651

Spino

1.19

0.76–1.87

0.455

PET

      

Yes

1

  

No

1.04

0.70–1.53

0.860

Location

      

Peripheral

1

  

Central

1.29

0.72–2.30

0.394

Prescribed BED10

      

≥ 150

1

     

< 150

1.31

0.89–1.93

0.168

1.26

0.85–1.88

0.256

Maximum BED10

      

≥ 251.6

1

  

< 251.6

1.43

0.96–2.11

0.076

T stage

      

T1a-c

1

     

T2a-b

1.43

0.97–2.11

0.073

1.08

0.90–1.29

0.411

  1. (HR: hazard ratio, CI: confidence interval, AACCI: age-adjusted Charlson comorbidity index, FEV1: forced expiratory volume in 1 s, BED10: biologically effective dose with alpha/beta = 10 Gy)
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Radiation Oncology

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