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Table 6 Comparison of G3-4 adverse events between TRT and non-TRT group

From: Efficacy and safety of thoracic radiotherapy in extensive-stage small-cell lung cancer patients receiving first-line immunotherapy plus chemotherapy: a propensity score matched multicentre retrospective analysis

Adverse Events

TRT Group

(n = 99)

non-TRT Group

(n = 98)

P value

Any Grades

81 (81.8%)

82 (83.7%)

0.874

G3-4 Totally

28 (28.3%)

27 (27.6%)

0.909

Leucopenia

/White-cell count decreased

4 (4.0%)

2 (2.0%)

0.683

Neutropenia

/Neutrophil count decreased

8 (8.1%)

12(12.2%)

0.356

Thrombocytopenia

/Platelet count decreased

1 (1.0%)

2 (2.0%)

0.621

Anaemia

1 (1.0%)

2 (2.0%)

0.621

Nausea

4 (4.0%)

7 (7.1%)

0.373

Decreased appetite

1 (1.0%)

3 (3.1%)

0.369

Constipation

0 (0%)

0 (0%)

/

Diarrhea

0 (0%)

2 (2.0%)

0.246

Radiation esophagitis

4 (4.0%)

/

/

Pneumonitis

6 (6.1%)

3 (3.1%)

0.498

Myocarditis

3 (2.0%)

0 (0%)

0.497

Hypothyroid

1 (1.0%)

0 (0%)

1.000

Atrial fibrillation

0 (0%)

1 (1.0%)

0.497

  1. G3-4: grade 3 to 4