Radiation therapy for retroperitoneal sarcoma: practice patterns in North America

Radiation Oncology

Table 4 Multivariable analysis for factors associated with receiving neoadjuvant radiation therapy compared to adjuvant radiation therapy

	Odds ratio	Confidence interval	p value
Sex
Female	Reference
Male	1.371	1.066–1.762	0.014
Race
Caucasian	Reference
African American	0.752	0.493–1.146	NS
Asian	0.934	0.488–1.790	NS
Other	1.440	0.475–4.363	NS
Unknown	1.521	0.442–5.236	NS
Ethnicity
Hispanic	Reference
Not Hispanic	3.022	1.586–5.760	0.001
Unknown	2.188	0.892–5.366	NS
Great Circle Distance	1.005	1.001–1.010	0.024
Facility Type
Community Cancer Program	Reference
Academic/Research Program	6.162	2.531–15.001	< 0.0001
Comprehensive Community Cancer Program	2.345	0.976–5.631	NS
Integrated Network Cancer Program	4.261	1.405–12.924	0.011
Unknown	4.860	1.777–13.293	0.002
Year of Diagnosis	1.175	1.093–1.263	< 0.0001
Annual Hospital Volume
Average < 5 cases per year	Reference
Average 5–10 cases per year	1.762	0.773–4.015	NS
Average > 10 cases/year	14.795	6.058–36.136	< 0.0001
Tumor differentiation
Well differentiated	Reference
Moderately differentiated	0.827	0.479–1.427	NS
Poorly differentiated	0.487	0.317–0.749	NS
Undifferentiated	0.734	0.442–1.218	NS
Unknown	0.889	0.558–1.416	NS
Histology
Leiomyosarcoma	Reference
Liposarcoma	0.574	0.409–0.805	0.001
Other	0.842	0.563–1.259	NS
Tumor size
≤ 10 cm	Reference
> 10 cm	2.009	1.477–2.733	< 0.0001
Tumor Grade
Grade 1	Reference
Grade 2	0.758	0.398–1.443	NS
Grade 3	0.873	0.532–1.431	NS
Unknown	0.979	0.564–1.699	NS

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