Table 2 Patient characteristic in locally advanced upper rectal cancer after matching
Variable | Overall population | Radiotherapy group (%) (n = 69) | Non-radiotherapy group (%) (n = 138) | P-value |
|---|---|---|---|---|
Age | ||||
≤ 60 years | 162 | 58 (84.1) | 104 (75.4) | 0.153 |
> 60 years | 45 | 11 (15.9) | 34 (24.6) | |
Sex | ||||
Female | 73 | 27 (39.1) | 46 (33.3) | 0.411 |
Male | 134 | 42 (60.9) | 92 (66.7) | |
Preoperative CEA(ng/ml) | ||||
< 5 | 148 | 49 (71.0) | 99 (71.7) | 0.913 |
≥ 5 | 59 | 20 (29.0) | 39 (28.3) | |
Distance from anal verge(cm) | ||||
≤ 12 | 194 | 63 (91.3) | 131 (94.9) | 0.366 |
> 12 | 13 | 6 (8.7) | 7 (5.1) | |
Pathological differentiation degree | ||||
High/Moderate differentiation | 198 | 64 (92.8) | 134 (97.1) | 0.164 |
Low differentiation | 9 | 5 (7.2) | 4 (2.9) | |
Circumferential margin status | ||||
Positive | 0 | 0 (0.0) | 0 (0.0) | – |
Negative | 207 | 69 (100.0) | 138 (100.0) | |
Lymphovascular invasion | ||||
Yes | 16 | 7 (10.1) | 9 (6.5) | 0.357 |
No | 191 | 62 (89.9) | 129 (93.5) | |
Perineural invasion | ||||
Yes | 11 | 5 (7.2) | 6 (4.3) | 0.512 |
No | 196 | 64 (92.8) | 132 (95.7) | |
Number of lymph nodes dissected | ||||
< 12 | 142 | 47 (68.1) | 95 (68.8) | 0.916 |
≥ 12 | 65 | 22 (31.9) | 43 (31.2) | |
pT stage | ||||
Tis-T3 | 93 | 31 (44.9) | 62 (44.9) | 1.000 |
T4 | 114 | 38 (55.1) | 76 (55.1) | |
pN stage | ||||
N0-1 | 153 | 48 (69.6) | 105 (76.1) | 0.314 |
N2 | 54 | 21 (30.4) | 33 (23.9) | |
pTNM stage | ||||
pCR-II | 81 | 22 (31.9) | 59 (42.8) | 0.131 |
III | 126 | 47 (68.1) | 79 (57.2) | |
4 ~ 6 months adjuvant chemotherapy | ||||
Yes | 87 | 37 (53.6) | 50 (36.2) | 0.017 |
No | 120 | 32 (46.4) | 88 (63.8) | |