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Table 3 Potential predictors of distant metastasis in patients with early-stage NSCLC treated with SBRT

From: A PET/CT radiomics model for predicting distant metastasis in early-stage non–small cell lung cancer patients treated with stereotactic body radiotherapy: a multicentric study

 

Univariable logistic regression

 

Multivariable logistic regression

Variables

OR (95%CI)

P

 

OR (95%CI)

P

CT score

2.526 (1.544–4.131)

< 0.001

 

2.435 (1.549–3.829)

< 0.001

PET score

1.929 (1.056–3.522)

0.033

 

1.769 (1.094–2.860)

0.020

Age(years)

0.979 (0.918–1.044)

0.523

 

-

-

Sex (female vs. male)

2.505 (0.779–8.054)

0.123

 

-

-

Smoke (no vs. yes)

0.852 (0.241–3.009)

0.804

 

-

-

ECOG (0 vs. 1)

0.749 (0.278–2.020)

0.569

 

-

-

Tumor size (cm)

0.896 (0.495–1.621)

0.716

 

-

-

Localization (central vs. peripheral)

2.037 (0.238–17.462)

0.516

 

-

-

Pathological diagnosis (yes vs. no)

1.608 (0.837–3.092)

0.154

 

-

-

SUVmax

1.010 (0.909–1.121)

0.855

 

-

-

BED10 (Gy)

1.001 (0.972–1.030)

0.961

 

-

-

  1. SBRT, Stereotactic body radiotherapy; NSCLC, non-small cell lung cancer; ECOG, Eastern Cooperative Oncology Group; OR, odds ratio; CI, confidence interval; BED, biological equivalent dose, α/β = 10