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Table 3 Dosimetric outcomes for 140 oART fraction of uterine cervical cancer

From: Prospects for daily online adaptive radiotherapy for cervical cancer: Auto-contouring evaluation and dosimetric outcomes

ROIs

Dosimetric metrics

A-Adapted plan

A-Scheduled plan

S-Adapted plan

S-Scheduled plan

p1 value

p2 value

CTV-N

V100% (%)

99.83 ± 0.34

99.94 ± 0.09

99.98 ± 0.05

99.95 ± 0.07

 < 0.05

 < 0.05

CTV-U

V100% (%)

99.35 ± 1.88

98.52 ± 3.80

100.00 ± 0.00

98.93 ± 3.06

 < 0.05

 < 0.05

CTV-C

V100% (%)

99.30 ± 1.15

98.10 ± 3.31

99.95 ± 0.11

98.36 ± 2.85

 < 0.05

 < 0.05

PTV-N

V100% (%)

96.56 ± 4.05

97.86 ± 0.95

97.96 ± 1.54

98.16 ± 0.78

 < 0.05

 < 0.05

PTV-U

V100% (%)

94.20 ± 5.50

93.51 ± 5.26

98.52 ± 1.50

94.27 ± 4.83

 < 0.05

 < 0.05

PTV-C

V100% (%)

93.01 ± 4.35

93.84 ± 43.67

96.74 ± 2.56

94.20 ± 3.99

 < 0.05

 < 0.05

Bladder

V40Gy (%)

36.80 ± 6.87

40.55 ± 10.53

42.63 ± 8.58

43.16 ± 9.19

 = 0.62

 < 0.05

V30Gy (%)

52.55 ± 6.68

56.47 ± 9.54

59.29 ± 9.70

60.66 ± 8.86

 = 0.22

 < 0.05

V20Gy (%)

70.63 ± 7.66

74.20 ± 10.02

76.96 ± 11.13

79.38 ± 10.80

 = 0.04

 < 0.05

V10Gy (%)

97.18 ± 2.40

98.44 ± 2.02

98.16 ± 1.85

98.63 ± 1.95

 = 0.04

 < 0.05

Dmean (Gy)

1.13 ± 0.15

1.23 ± 0.22

1.26 ± 0.19

1.30 ± 0.19

 = 0.11

 < 0.05

D50% (Gy)

1.14 ± 0.09

1.20 ± 0.14

1.23 ± 0.13

1.25 ± 0.13

 = 0.14

 < 0.05

Rectum

V40Gy (%)

53.94 ± 12.24

70.00 ± 12.62

55.08 ± 11.92

70.26 ± 12.58

 < 0.05

 = 0.43

V30Gy (%)

70.25 ± 9.60

83.17 ± 8.48

70.83 ± 9.59

82.23 ± 8.62

 < 0.05

 = 0.62

V20Gy (%)

82.87 ± 6.10

91.44 ± 5.59

82.95 ± 5.59

89.78 ± 4.46

 < 0.05

 = 0.91

V10Gy (%)

92.89 ± 3.88

95.44 ± 3.74

93.24 ± 3.24

95.11 ± 2.79

 < 0.05

 = 0.41

Dmean (Gy)

1.48 ± 0.21

1.72 ± 0.17

1.50 ± 0.20

1.72 ± 0.15

 < 0.05

 = 0.50

D50% (Gy)

1.33 ± 0.13

1.53 ± 0.14

1.34 ± 0.12

1.52 ± 0.13

 < 0.05

 = 0.48

Bone Marrow

V10Gy (%)

86.77 ± 1.72

87.86 ± 1.75

87.16 ± 1.69

87.30 ± 2.06

 = 0.52

 = 0.06

D90% (Gy)

0.31 ± 0.02

0.32 ± 0.02

0.31 ± 0.02

0.31 ± 0.03

 = 0.15

 = 0.14

Dmean (Gy)

0.94 ± 0.04

0.98 ± 0.04

0.95 ± 0.03

0.98 ± 0.03

 < 0.05

 = 0.01

Femur head left

V30Gy (%)

2.47 ± 2.19

3.22 ± 2.00

2.71 ± 1.85

3.26 ± 1.79

 = 0.01

 = 0.34

D5% (Gy)

0.96 ± 0.09

1.00 ± 0.07

0.97 ± 0.07

1.01 ± 0.07

 < 0.05

 = 0.12

Dmean (Gy)

0.55 ± 0.06

0.57 ± 0.05

0.55 ± 0.04

0.56 ± 0.03

 = 0.04

 = 0.51

Femur head right

V30Gy (%)

3.24 ± 2.16

4.40 ± 1.86

3.75 ± 1.80

4.16 ± 1.41

 = 0.04

 = 0.03

D5% (Gy)

0.99 ± 0.10

1.05 ± 0.07

1.00 ± 0.07

1.04 ± 0.06

 < 0.05

 = 0.23

Dmean (Gy)

0.55 ± 0.05

0.57 ± 0.03

0.56 ± 0.03

0.56 ± 0.02

 = 0.68

 = 0.07

Bowel

V40Gy (%)

34.01 ± 9.12

38.40 ± 10.98

34.04 ± 7.99

39.24 ± 10.92

 < 0.05

 = 0.97

V30Gy (%)

49.76 ± 9.09

57.81 ± 10.14

49.98 ± 7.42

58.84 ± 9.86

 < 0.05

 = 0.83

V20Gy (%)

62.88 ± 8.13

75.79 ± 9.09

62.79 ± 6.73

75.82 ± 9.49

 < 0.05

 = 0.92

V10Gy (%)

78.12 ± 7.48

90.36 ± 8.05

78.27 ± 6.73

89.99 ± 8.34

 < 0.05

 = 0.86

D2cm3 (cGy)

1.96 ± 0.10

1.98 ± 0.09

1.95 ± 0.08

1.97 ± 0.09

 = 0.02

 = 0.19

V40Gy (cm3)

247.91 ± 83.42

280.30 ± 103.52

246.44 ± 70.16

284.79 ± 97.21

 < 0.05

 = 0.87

V47Gy (cm3)

176.98 ± 59.16

206.19 ± 80.72

174.94 ± 46.47

207.83 ± 73.58

 < 0.05

 = 0.75

  1. p1 value represents the comparison between S-Adapted plan and S-Scheduled plan; p2 value represents the comparison between A-Adapted plan and S-Adapted plan
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Radiation Oncology

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