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Table 1 List of dosimetric outcomes for all emulated125 daily fractions of 5 patients

From: Evaluation of PTV margins with daily iterative online adaptive radiotherapy for postoperative treatment of endometrial and cervical cancer: a prospective single-arm phase 2 study

Target and OAR

Goal

Adapted plan, 5 mm margins

Adapted plan, conventional margin

p value

CTV-N

V100% (%)

99.59 ± 0.14

99.7 ± 0.19#

p < 0.05

CTV-V

V100% (%)

99.54 ± 0.30

99.85 ± 0.15#

p < 0.05

PCTV-N

V100% (%)

95.90 ± 0.20

96.04 ± 0.55#

p < 0.05

PCTV-V

V100% (%)

95.47 ± 0.81

95.51 ± 1.46

p = 0.801

Bladder

V40Gy (%)

20.78 ± 4.29

35.53 ± 6.36#

p < 0.05

 

V30Gy (%)

33.94 ± 5.64

52.10 ± 7.10#

p < 0.05

 

V20Gy (%)

54.06 ± 6.94

71.81 ± 6.84#

p < 0.05

 

V10Gy (%)

90.18 ± 5.81

91.95 ± 5.27#

p < 0.05

 

Dmean (Gy)

0.99 ± 0.08

1.22 ± 0.09#

p < 0.05

Rectum

V40Gy (%)

38.27 ± 7.66

80.35 ± 9.11#

p < 0.05

 

V30Gy (%)

59.42 ± 8.52

89.34 ± 6.59#

p < 0.05

 

V20Gy (%)

75.49 ± 7.60

95.20 ± 4.29#

p < 0.05

 

V10Gy (%)

94.06 ± 4.14

99.29 ± 1.45#

p < 0.05

 

Dmean (Gy)

1.26 ± 0.10

1.67 ± 0.08#

p < 0.05

Bone Marrow

V40Gy (%)

14.76 ± 1.53

21.36 ± 2.06#

p < 0.05

 

V10Gy (%)

76.88 ± 2.24

81.08 ± 2.74#

p < 0.05

 

Dmean (Gy)

0.88 ± 0.03

0.99 ± 0.04#

p < 0.05

 

D90% (Gy)

0.20 ± 0.03

0.26 ± 0.04#

p < 0.05

Femur head left

V30Gy (%)

0.52 ± 0.74

1.94 ± 1.71#

p < 0.05

 

Dmean (Gy)

0.45 ± 0.03

0.50 ± 0.04#

p < 0.05

 

D5% (Gy)

0.82 ± 0.08

0.96 ± 0.14#

p < 0.05

Femur head right

V30Gy (%)

0.51 ± 0.67

1.77 ± 1.77#

p < 0.05

 

Dmean (Gy)

0.45 ± 0.02

0.50 ± 0.04#

p < 0.05

 

D5% (Gy)

0.84 ± 0.06

0.94 ± 0.13#

p < 0.05

Bowel

V40Gy (%)

13.26 ± 3.3

18.32 ± 4.63#

p < 0.05

 

V30Gy (%)

27.45 ± 4.82

33.39 ± 5.82#

p < 0.05

 

V20Gy (%)

50.98 ± 4.1

54.78 ± 5.38#

p < 0.05

 

V10Gy (%)

75.14 ± 4.90

77.84 ± 6.30#

p < 0.05

 

D2cm3 (Gy)

1.86 ± 0.01

1.89 ± 0.01#

p < 0.05

 

V40Gy (cm3)

87.56 ± 24.32

121.0 ± 33.29#

p < 0.05

 

V47Gy (cm3)

0.95 ± 0.58

2.5 ± 2.13#

p < 0.05

  1. Abbreviations: OAR, organs at risk
  2. Note: Results are presented as the average value together with one standard deviation. p value represents the outcome of t test
  3. # Adapted plan with 5 mm margins compared with adapted plan with conventional margin, p < 0.05