Table 2 Univariate analysis of various potential prognostic factors associated with OS
Factor | MST (months) | Survival rate (%) | HR (95% CI) | P | |||
|---|---|---|---|---|---|---|---|
1-y | 3-y | 5-y | 8-y | ||||
Sex | 0.039 | ||||||
Male | 29.1 | 84.3 | 41.9 | 29.2 | 17.9 | 0.60 (0.36–0.99) | |
Female | 50.8 | 91.5 | 62.0 | 45.8 | 41.7 | ||
Age at diagnosis (year) | 0.427 | ||||||
≤ 65 | 36.8 | 86.6 | 50.7 | 40.6 | 29.6 | 0.81 (0.48–1.37) | |
> 65 | 35.0 | 87.1 | 49.4 | 28.3 | 21.2 | ||
ECOG PS | 0.287 | ||||||
0 | 36.8 | 87.2 | 52.2 | 39.1 | 28.7 | 0.65 (0.29–1.45) | |
1–2 | 23.5 | 83.3 | 50.0 | – | – | ||
cT stage | 0.966 | ||||||
T3 | 36.8 | 86.6 | 51.9 | 38.2 | 26.5 | 0.99 (0.50–1.94) | |
T4 | 22.7 | 87.5 | 42.9 | 35.7 | 35.7 | ||
cN stage | 0.028 | ||||||
N0 | 44.8 | 95.7 | 51.5 | 31.6 | 31.6 | 1.21 (1.04–1.42) | |
N1 | 60.1 | 87.5 | 59.9 | 50.7 | 30.1 | ||
N2–3 | 20.2 | 77.8 | 32.9 | 19.8 | 19.8 | ||
8th AJCC stage | 0.966 | ||||||
II–III | 36.8 | 86.6 | 51.9 | 38.2 | 26.5 | 0.99 (0.50–1.94) | |
IV | 22.7 | 87.5 | 42.9 | 35.7 | 35.7 | ||
Radiation dose | 0.353 | ||||||
≥ 50 Gy, ≤ 59.4 Gy | 35.0 | 83.3 | 47.2 | 29.1 | 19.4 | 1.29 (0.76–2.19) | |
> 59.4 Gy, ≤ 66 Gy | 36.8 | 88.2 | 51.3 | 40.1 | 29.9 | ||