Radiotherapy-induced diffuse myocardial fibrosis in early-stage breast cancer patients – multimodality imaging study with six-year follow-up

Table 2 Global and regional T1, ECV, T2, and IBS values

			Global	Basal	Mid	Apical	p
T1	(ms)	median (Q₁-Q₃)	1235 (1199–1273)	1220 (1193–1262)	1219 (1179–1268)	1252 (1168–1319)	0.393 ¹
		*% abnormal	90.00	53.33	50.00	66.67	0.529²
ECV	(%)	median (Q₁-Q₃)	28.05 (26.11–30.23)	27.40 (25.23–28.78)	26.69 (24.87–29.29)	28.98 (26.65–32.51)	0.008 ¹
		*% abnormal	80.00	46.67	43.33	60.00	0.038 ²
T2	(ms)	median (Q₁-Q₃)	35.54 (34.61–38.23)	35.82 (34.29–37.39)	34.88 (34.03–36.97)	36.85 (34.40–41.03)	0.010 ¹
		*% abnormal	6.90	3.45	0.00	3.45	0.368²
IBS	(dB)	mean (SD)	1.04 (2.80)	1.99 (3.93)	1.06 (3.73)	-0.79 (4.16)	0.080¹
		*% abnormal	76.67	46.15	61.54	32.14	0.368²

One patient’s T2 values were missing, and two to four patients’ global or regional IBS values were missing and could not be evaluated. ECV, extracellular volume; IBS, integrated backscatter change from baseline to 6-year follow-up; *% abnormal, percentage of patients with abnormally high segmental values in a respective region; dB, decibel; p, p-value from ¹Friedmans test or ²Cochran’s Q test for the difference between the basal, mid, and apical regions.

ISSN: 1748-717X