Table 4 Effects of radiation BED₁₀ dose on liver toxicity in the entire cohort and subgroup analysis based on GTV equivalent diameter

BED ≤ 78

BED > 78

P value

BED ≤ 78

BED > 78

P value

BED ≤ 78

BED > 78

P value

Mean baseline ALBI score

-1.98 ± 0.68

-2.00 ± 0.82

0.914

-1.99 ± 0.91

-1.71 ± 0.89

0.394

-1.97 ± 0.62

-2.39 ± 0.52

0.018

Mean maximum ALBI score at four months

-1.54 ± 1.07

-1.61 ± 1.07

0.751

-1.49 ± 1.45

-1.39 ± 1.12

0.794

-1.56 ± 0.97

-1.94 ± 0.93

0.123

Clinical liver decompensation at four months (%)

22.4

19.3

0.674

30.8

22.9

0.574

20.4

13.6

0.492

Clinical liver decompensation at one year (%)

40.3

29.8

0.224

38.5

31.4

0.646

40.7

27.3

0.270