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Table 1 Patient characteristics and treatment of the entire cohort

From: Radiation dose is associated with improved local control for large, but not small, hepatocellular carcinomas

  

All patients N = 128 (%)

Age (mean ± SD, years)

 

64.29 ± 9.19

Gender male

 

105 (82.0)

ECOG

0

63 (50.0)

 

1

51 (40.5)

 

2

11 (8.7)

 

3

1 (0.8)

Child-Pugh Group

A

81 (66.4)

 

B

34 (27.9)

 

C

7 (5.7)

ALBI grade

1

23 (25.0)

 

2

51 (55.4)

 

3

18 (19.6)

Received prior local therapy

 

94 (73.4)

Vascular invasion

 

41 (32)

Dose per fraction

Conventional (180–200 cGy/Fx)

7 (5.5)

 

Hypofractionated (201–500 cGy/Fx)

79 (61.7)

 

Ultrahypofractionated (501 cGy/Fx≤)

42 (32.8)

Number of fractions

1–5

42 (32.8)

 

6–20

37 (28.9)

 

> 20

49 (38.3)

Planned treatment break

 

34 (26.6)

RT treatment modality

Proton

36 (28.1)

GTV volume (median, Q1, Q3 cm³)

 

113, 53, 282

GTV equivalent sphere diameter (median, Q1, Q3 cm)

 

6.0, 4.6, 8.1

BED10 (median, Q1, Q3, Gy)

 

78, 69, 98

Survival (median, months)

 

18.31