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Table 2 Dosimetry and dose reduction with intensity modulated proton therapy (IMPT)

From: Proton therapy and oral mucositis in oral & oropharyngeal cancers: outcomes, dosimetric and NTCP benefit

 

IMPT

IMRT

Average of % difference

HR PTV D95 (Avg)

97%

98%

NS

HR CTV D98 (Avg)

98%

100%

NS

LR PTV D95 (Avg)

97%

98%

NS

LR CTV D98 (Avg)

99%

100%

NS

Oral mucosa D mean (Avg)

30.42 GyE

38.05 Gy

13.5% reduction

Spared oral mucosa D mean (Avg)

19.17 GyE

32.16 Gy

38.6% reduction

Spinal cord D max (Avg)

19.64 GyE

35.76 Gy

44.4% reduction

Brainstem D max (Avg)

25.86 GyE

42.03 Gy

36.7% reduction

C/L parotid D mean (Avg)

20.56 GyE

25.26 Gy

28.3% reduction

  1. HR PTV—High risk planning target volume, HR CTV—High risk clinical target volume, LR PTV—Low risk planning target volume, LR CTV—Low risk clinical target volume, D95—Dose received by 95% of volume, D98—Dose received by 98% of volume, Avg—Average, Max—Maximum, C/L—Contralateral, NS—Not Significant, Gy—Gray, GyE Gray equivalent
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Radiation Oncology

ISSN: 1748-717X

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