Table 1 Patient characteristics
Baseline features | Overall | Responders (n = 12) | Non-resp. (n = 12) | p-value | |||
|---|---|---|---|---|---|---|---|
Number/Median | Range (IQR) % | Number/Median | Range (IQR)/% | Number/Median | Range (IQR)/% | ||
Sex | |||||||
Female | 4 | 16.7 | 2 | 16.7 | 2 | 16.7 | 1 |
Male | 20 | 83.3 | 10 | 83.3 | 10 | 83.3 | 1 |
Age (years) | 69 | 50–84 (21) | 68.5 | 58–87 (21.5) | 68.5 | 44–86 (32.5) | 0.80 |
Etiology | |||||||
Alcohol | 9 | 37.5 | 5 | 41.7 | 4 | 33.3 | 1 |
NASH | 3 | 12.5 | 1 | 8.3 | 2 | 16.7 | 1 |
Hepatitis B | 4 | 16.7 | 1 | 8.3 | 3 | 25 | 0.59 |
Hepatitis C | 6 | 25 | 4 | 33.3 | 2 | 16.7 | 0.64 |
Unknown | 6 | 25 | 3 | 25 | 3 | 25 | 1 |
Multiple | 4 | 16.7 | 2 | 16.7 | 2 | 16.7 | |
Child–Pugh A | 19 | 79.2 | 10 | 83.3 | 9 | 75 | 1 |
Child–Pugh B | 5 | 20.8 | 2 | 16.7 | 3 | 25 | |
AFP [ng/ml] | 5.25 | 1.6–35,754 (7) | 5.25 | 1.6–21.5 (4.65) | 5.45 | 2.0–35,754 (32.15) | 0.77 |
AFP ≥ 20 ng/ml | 4 | 16.7 | 1 | 8.3 | 3 | 25 | 0.59 |
Portal vein thrombosis | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Sum lesion diameter [cm] | 3 | 1.1–10.9 (3.23) | 2.9 | 1.7–10.3 (1.08) | 3.5 | 1.1–10.9 (4.75) | 0.49 |
Max. tumor diameter [cm] | 2.5 | 1.1–10.3 (1.63) | 2.7 | 1.7–10.3 (0.8) | 2.3 | 1.1–10.0 (5.67) | 0.31 |
Tumor number treated | |||||||
1 | 16 | 66.7 | 10 | 83.3 | 6 | 50 | 0.19 |
2 | 8 | 33.3 | 2 | 16.7 | 6 | 50 | |