Fig. 3

Kaplan–Meier curves demonstrating time to systemic progression in relation to increasing and decreasing miR-21/-210 levels. Note the significantly shorter time to systemic progression in patients with increasing miR-21 levels (A). No significant difference in time to systemic progression between increasing and decreasing miR-210 levels was observed (B). NE – not evaluable because median time to systemic progression was not reached within the 40 months of study follow-up