Fig. 2

Waterfall plots illustrating miR dynamics per individual study subject for miR-21 (a) and miR-210 (b). To enable optimized depiction (i.e. decreasing miR values displayed as negative numbers), 2^−ΔΔCт values between 0 and 1 (implicating decrease) were transformed applying the formula: 1/− (2^−ΔΔCт). Note the significant increase of miR-21 in non-responders