Table 1 Clinical characteristics of 962 breast cancer patients in the TCGA-BRCA cohort
From: HLA-DQA1 expression is associated with prognosis and predictable with radiomics in breast cancer
Variables | Total (n = 962) | LHD-group (n = 470) | HHD-group (n = 492) | p |
|---|---|---|---|---|
HLA-DQA1 expression, (\({\overline{\text{X}}} \pm {\text{SD}}\))* | < 0.001 | |||
4.147 ± 1.220 | 3.146 ± 0.744 | 5.103 ± 0.713 | ||
Age, n (%) | 0.091 | |||
~ 59 | 521 (54) | 241 (51) | 280 (57) | |
60~ | 441 (46) | 229 (49) | 212 (43) | |
PR_status, n (%) | 0.189 | |||
Negative | 307 (32) | 140 (30) | 167 (34) | |
Positive | 655 (68) | 330 (70) | 325 (66) | |
HER2_status, n (%) | 0.033 | |||
Negative | 512 (53) | 233 (50) | 279 (57) | |
Equivocal/Indeterminate | 304 (32) | 167 (36) | 137 (28) | |
Positive | 146 (15) | 70 (15) | 76 (15) | |
ER_status, n (%) | 0.001 | |||
Negative | 216 (22) | 84 (18) | 132 (27) | |
Positive | 746 (78) | 386 (82) | 360 (73) | |
Radiotherapy, n (%) | 0.319 | |||
No | 456 (47) | 231 (49) | 225 (46) | |
Yes | 506 (53) | 239 (51) | 267 (54) | |
Chemotherapy, n (%) | 0.006 | |||
No | 426 (44) | 230 (49) | 196 (40) | |
Yes | 536 (56) | 240 (51) | 296 (60) | |
T_stage, n (%) | 0.124 | |||
T1 | 258 (27) | 126 (27) | 132 (27) | |
T2 | 547 (57) | 256 (54) | 291 (59) | |
T3/T4 | 157 (16) | 88 (19) | 69 (14) | |
N_stage, n (%) | 0.785 | |||
N0 | 447 (46) | 221 (47) | 226 (46) | |
N1/N2/N3/NX | 515 (54) | 249 (53) | 266 (54) | |
M_stage, n (%) | 0.482 | |||
M0 | 797 (83) | 394 (84) | 403 (82) | |
M1/MX | 165 (17) | 76 (16) | 89 (18) | |
Histological_type, n (%) | 0.006 | |||
ILC | 187 (19) | 77 (16) | 110 (22) | |
IDC | 682 (71) | 336 (71) | 346 (70) | |
Other | 93 (10) | 57 (12) | 36 (7) | |
OS, n (%) | 0.004 | |||
Alive | 829 (86) | 389 (83) | 440 (89) | |
Dead | 133 (14) | 81 (17) | 52 (11) | |
OS.time, Median(Q1, Q3) | ||||
29.4 (16.3, 59.4) | 29.4 (15.9, 55.8) | 29.7 (16.6, 64.0) | 0.404 | |