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Table 1 Clinical characteristics of SARP patients

From: Analysis of clinical and physical dosimetric factors that determine the outcome of severe acute radiation pneumonitis in lung cancer patients

Clinical characteristic

Total (N = 66)

Deceased patients (n = 31)

Surviving patients (n = 35)

P value

Age (years)

    

Median (IQR)

64.50 (63.00–67.00)

66.00 (62.00–71.00)

64.00 (62.00–67.00)

0.175

Gender

   

0.263

Male

49.00 (74.24%)

25.00 (80.65%)

24.00 (68.57%)

Female

17.00 (25.76%)

6.00 (19.35%)

11.00 (31.43%)

ECOG PS

   

0.948

0–1

53.00 (80.30%)

25.00 (80.65%)

28.00 (80.00%)

2

13.00 (19.70%)

6.00 (19.35%)

7.00 (20.00%)

COPD

   

0.896

Yes

25.00 (37.88%)

12.00 (38.71%)

13.00 (37.14%)

No

41.00 (62.12%)

19.00 (61.29%)

22.00 (62.86%)

Smoking (pack-year)

   

0.828

< 20

35.00 (53.03%)

16.00 (51.61%)

19.00 (54.29%)

≥ 20

31.00 (46.97%)

15.00 (48.39%)

16.00 (45.71%)

Diabetes

   

0.855

Yes

8.00 (12.12%)

4.00 (12.90%)

4.00 (11.43%)

No

58.00 (87.88%)

27.00 (87.10%)

31.00 (88.57%)

Histology

    

SCC

38.00 (57.58%)

18.00 (58.06%)

20.00 (57.14%)

0.997

AC

13.00 (19.70%)

6.00 (19.35%)

7.00 (20.00%)

Other

15.00 (22.72%)

7.00 (22.58%)

8.00 (22.86%)

Ki-67

   

0.367

Median (IQR)

60.00 (40.00–60.00)

40.00 (0.00–60.00)

65.00 (40.00–80.00)

Lobe

    

Right middle

8.00 (12.12%)

2.00 (6.45%)

6.00 (17.14%)

0.342

Right upper

22.00 (33.33%)

10.00 (32.26%)

12.00 (34.29%)

0.862

Right lower

16.00 (24.24%)

9.00 (29.03%)

6.00 (17.14%)

0.250

Left upper

15.00 (22.72%)

7.00 (22.58%)

8.00 (22.86%)

0.979

Left lower

6.00 (9.09%)

3.00 (9.68%)

3.00 (8.57%)

1.000

AJCC 8 Stage

   

0.728

II

14.00 (21.21%)

6.00 (19.35%)

8.00 (22.86%)

III

52.00 (78.79%)

25.00 (80.65%)

27.00 (77.14%)

Prior lung cancer surgery

   

0.454

Yes

20.00 (30.30%)

8.00 (25.81%)

12.00 (34.29%)

No

46.000 (69.70%)

23.00 (74.19%)

23.00 (65.71%)

Chemotherapy

   

0.767

Concurrent chemotherapy

50.00 (75.76%)

24.00 (77.41%)

26.00 (74.29%)

Sequential chemotherapy

16.00 (24.24%)

7.00 (22.58%)

9.00 (25.71%)

RT dose received

   

0.127

40 or 58 Gy

24.00 (36.36%)

10.00 (32.26%)

14.00 (40.00%)

59–60 Gy

33.00 (50.00%)

19.00 (61.29%)

14.00 (40.00%)

61–65 Gy

9.00 (13.64%)

2.00 (6.45%)

7.00 (20.00%)