Table 5 Late adverse events following ultracentral radiation therapy according to the CTCAE v 5.0
All patient (n = 78) | No prior in-field radiotherapy (n = 50) | Patients with thoracic re-irradiation (n = 28) | p-value | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Grade 2 | Grade 3 | Grade 4 | Grade 5 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | ||
Pneumonitis | 12 | 3 | – | – | 6 | 1 | – | – | 6 | 2 | – | – | 0.12 |
Esophagitis | – | 1 | – | – | – | – | – | – | – | 1 | – | – | 0.36 |
Airway toxicity | 1 | 2 | – | – | 1 | 2 | – | – | – | – | – | – | 0.7 |
Hemorrhage | – | – | – | 3* | – | – | – | 1* | – | – | – | 2* | 0.13 |