Table 1 Detailed patient and tumor characteristics
Characteristic | N (%) |
|---|---|
Sex | |
Male | 35 (45.9) |
Female | 43 (55.1) |
Age (years): median (range) | 70.6 (38.9–96.7) |
Risk factors | |
COPD | 37 (47.4) |
ECOG performance status: median (range) | 2 (0 to 3) |
FEV1: median % (range) | 66.5 (23–112) |
DLCO: median % (range) | 60.5 (26–103) |
Histology | |
Adenocarcinoma | 36 (46.2) |
SCC | 27 (34.6) |
Other | 14 (17.9) |
No biopsy | 1 (1.3) |
Ultra-central tumor location | |
Hilum | 29 (37.2) |
Mediastinum | 22 (28.2) |
Mediastinum + Hilum | 15 (19.2) |
Parenchyma + Hilum | 12 (15.4) |
Patient disease status prior to treatment | |
Primary | 33 (42.3) |
Metastatic | 16 (20.5) |
Recurrent | 29 (37.2) |
PTV Volume (cc): median (range) | 66.6 (9.3–1201.8) |
PET Maximum SUV prior to treatment: Median (range) | 8.9 (1.3–30.2) |
Follow-up time (months): median (range) | 13.1 (0.3–102.3) |
Prior chemotherapy | |
Yes | 44 (56.4) |
No | 34 (43.6) |
Thoracic re-irradiation treatment characteristics (n = 28) | |
Previous thoracic radiation | |
EBRT | 17 (60.8) |
SBRT | 7 (25.0) |
Both | 4 (14.2) |
Dose of previous thoracic radiation (Gy) | |
EBRT: median (range) | 66 (50.0–70.2) |
SBRT: Median (range) | 50 (19.5–70.0) |
Time Interval from previous radiation (months): Median (range) | 16.1 (3.6–100.9) |