Table 2 Multivariate model of breast cancer-specific mortality and overall mortality in patients with breast conserving surgery

Radiotherapy

 < 0.001

 < 0.001

 Perform

Reference

Reference

 Refused

3.457 (2.977–4.014)

 < 0.001

2.879 (2.632–3.15)

 < 0.001

Age

 < 0.001

 < 0.001

  ≤ 50

Reference

Reference

  > 50

1.19 (1.092–1.296)

 < 0.001

1.806 (1.682–1.938)

 < 0.001

Income

 < 0.001

 < 0.001

  < 65,000

Reference

Reference

  ≥ 65,000

0.855 (0.796–0.918)

 < 0.001

0.864 (0.826–0.905)

 < 0.001

Marital

 < 0.001

 < 0.001

 Married

Reference

Reference

 Single

1.177 (1.068–1.298)

0.001

1.287 (1.201–1.379)

 < 0.001

 Divorced

1.389 (1.281–1.505)

 < 0.001

1.915 (1.822–2.013)

 < 0.001

Race

 < 0.001

 < 0.001

 White

Reference

Reference

 Black

1.274 (1.158–1.402)

 < 0.001

1.141 (1.064–1.223)

 < 0.001

 Others

0.78 (0.676–0.901)

0.001

0.728 (0.66–0.803)

 < 0.001

Grade

 < 0.001

 < 0.001

 Grade I + II

Reference

Reference

 Grade III + IV

2.542 (2.331–2.771)

 < 0.001

1.717 (1.622–1.818)

 < 0.001

Stage

 < 0.001

 < 0.001

 Stage I

Reference

Reference

 Stage II

3.172 (2.905–3.464)

 < 0.001

2.061 (1.958–2.169)

 < 0.001

 Stage III

9.868 (8.812–11.052)

 < 0.001

5.417 (4.981–5.891)

 < 0.001

Subtype

 < 0.001

 < 0.001

 HR + /HER-2 + 

Reference

Reference

 HR + /HER-2-

1.476 (1.284–1.697)

 < 0.001

1.127 (1.025–1.24)

0.013

 HR-/HER-2 + 

1.576 (1.294–1.919)

 < 0.001

1.301 (1.122–1.509)

 < 0.001

 HR-/HER-2-

2.87 (2.487–3.312)

 < 0.001

2.08 (1.877–2.304)

 < 0.001

Chemotherapy

0.008

 < 0.001

 No

Reference

Reference

 Yes

1.136 (1.034–1.247)

0.008

0.601 (0.565–0.639)

 < 0.001