Table 4 Previous reports of photon therapy or particle therapy for squamous cell carcinoma of the nasal cavity and paranasal sinus
Author | Year | Number of patients | Cases with IC | Cases with surgery | Radiotherapy modality | Median dose | T4b cases | Median follow-up (years) | OS (year) | PFS (year) | LC (year) |
|---|---|---|---|---|---|---|---|---|---|---|---|
Guan et al. [9] | 2014 | 59 | 7% | 39% | X-ray | 66 Gy/33 fr 70 Gy/35 fr | 24% | 3.3 | 69% (3) | 60% (3) | 63% (3) |
Duru Birgi et al. [10] | 2015 | 43 | 7% | 58% | X-ray | 55 Gy/20 fr (R) 60 Gy/30 fr (PO) | 14% | 2.7 | 80% (2) | 71% (2) | 81% (2) |
Park et al. [11] | 2016 | 73 | NR | 29% | X-ray | 72 Gy (R) 60 Gy (PO) | NR | NR | 88% (2) | NR | 69% (2) |
85% (5) | 60% (5) | ||||||||||
Pare et al. [12] | 2017 | 68 | 59% | 100% | X-ray | 64 Gy/32 fr | 9% | 5.7 | 68% (2) | 56% (2) | 63% (2) |
58% (5) | 53% (5) | 63% (5) | |||||||||
Slevin et al. [13] | 2021 | 56 | 21% | 73% | X-ray | 65 Gy/30 fr (R) 60 Gy/30 fr (PO) | NR | 3.8 | 63% (3) | 53% (3) | NR |
Abdelmeguid et al. [14] | 2021 | 123 | 100% | 39% | X-ray | NR | 37% | 2.7 | 52% (3) | NR | NR |
44% (5) | |||||||||||
Russo et al. [4] | 2016 | 54 | 2% | 69% | Proton | 72.8 GyE (including BID) | 63% | 6.8 | 67% (2) | 57% (2) | 80% (2) |
47% (5) | 48% (5) | 80% (5) | |||||||||
Toyomasu et al. [5] | 2018 | 59 | 0% | 0% | Proton Carbon | 65 GyE/26 fr | 27% | 5.5 | 56% (3) | 43% (3) | 54% (3) |
42% (5) | 35% (5) | 50% (5) | |||||||||
Current study | 2023 | 37 | 11% | 27% | Proton | 74 GyE/37 fr (R) 66 GyE/33 fr (PO) | 57% | 4.4 | 58% (4) | 43% (4) | 58% (4) |