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Table 3 Grade 2 or higher late adverse events

From: Proton beam therapy in multimodal treatment for locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus

No

Age

Sex

Location

T-stage

Group

Dose (Gy, RBE)

Status

Survival (years)

Late adverse event

Grade

Onset from PBT (years)

1

68

M

Maxillary

3

B

70

Alive

4.8

Vision decreased (IpL)

3

2.2

2

67

M

Maxillary

4a

B

78

Alive

12.3

Vision decreased (IpL)

4

0.9

3

61

M

Ethmoid

4b

B

74

Alive

8.3

Retinopathy (IpL)

3

3.3

4

73

F

Maxillary

3

B

70

Alive

3.8

Retinopathy (IpL)

3

3.3

5

47

M

Nasal

4b

C

70

Alive

10.1

Retinopathy (IpL)

3

5.2

6

66

F

Maxillary

4a

C

74

Alive

7

Retinal vascular disorder (IpL)

3

4.2

7

64

F

Ethmoid

4b

C

76

Dead

1.7

Central nervous system necrosis

2

0.5

8

46

M

Ethmoid

4b

C

79.2

Dead

4.4

Central nervous system necrosis

3

1.5

9

53

F

Ethmoid

4b

C

79.2

Dead

3.6

Fracture

2

unknown

  1. RBE: relative biological effectiveness, PBT: proton beam therapy, IpL: ipsilateral side