Table 1 The clinical indices comparison for forty test patients with the unit of Gy (mean ± standard deviation). p1: significant difference between ground truth and predicted dose by shared encoder network. p2: significant difference between ground truth and predicted fluence generated dose. Results with P < 0.05 indicated statistical significance and were labeled with *

71.1 ± 0.6

71.2 ± 0.4

70.5 ± 1.1

0.24

0.00^*

73.4 ± 0.6

73.1 ± 0.4

73.6 ± 0.5

0.06

0.00^*

76.8 ± 0.8

76.1 ± 0.8

78.0 ± 1.3

0.00^*

0.00^*

63.8 ± 1.8

64.5 ± 1.6

63.9 ± 1.5

0.00^*

0.13

70.2 ± 1.1

70.1 ± 1.1

70.4 ± 1.1

0.38

0.00^*

76.8 ± 0.9

76.1 ± 0.8

78.0 ± 1.3

0.00^*

0.00^*

57.1 ± 1.7

57.6 ± 1.4

56.3 ± 1.6

0.00^*

0.00^*

63.7 ± 2.0

63.6 ± 1.7

63.6 ± 1.9

0.62

0.66

76.7 ± 1.2

75.9 ± 1.5

77.8 ± 1.7

0.00^*

0.00^*

67.6 ± 2.5

66.6 ± 2.2

66.4 ± 2.4

0.00^*

0.00^*

68.9 ± 2.6

68.7 ± 2.2

68.7 ± 2.5

0.40

0.78

70.9 ± 3.0

71.4 ± 2.7

71.9 ± 3.2

0.02^*

0.00^*

67.3 ± 2.8

66.5 ± 2.1

66.1 ± 2.6

0.00^*

0.00^*

68.6 ± 2.9

68.4 ± 2.3

68.2 ± 2.7

0.45

0.17

70.3 ± 3.3

70.9 ± 3.0

71.1 ± 3.3

0.01^*

0.02^*

35.5 ± 1.3

36.0 ± 1.6

35.9 ± 2.1

0.02^*

0.16

55.9 ± 5.5

55.1 ± 4.9

55.5 ± 4.9

0.03^*

0.17

35.8 ± 21.4

37.5 ± 22.4

37.0 ± 22.3

0.01^*

0.24

36.5 ± 21.4

38.0 ± 22.4

37.4 ± 21.7

0.03^*

0.09

43.8 ± 19.6

46.5 ± 19.2

45.5 ± 20.4

0.00^*

0.05

6.3 ± 2.9

6.7 ± 3.0

6.0 ± 2.6

0.24

0.40

6.4 ± 3.3

6.8 ± 3.5

6.2 ± 3.2

0.28

0.95

18.9 ± 6.9

19.4 ± 6.7

18.7 ± 6.7

0.03^*

0.32

19.5 ± 7.5

19.4 ± 6.6

18.7 ± 6.6

0.51

0.00^*

43.1 ± 6.2

42.7 ± 5.7

42.3 ± 6.0

0.02^*

0.00^*

42.2 ± 4.7

42.1 ± 4.2

41.6 ± 4.7

0.93

0.00^*

38.4 ± 4.4

38.7 ± 4.8

38.5 ± 5.0

0.29

0.96

38.5 ± 3.9

39.0 ± 4.0

38.6 ± 4.4

0.08

0.96

19.0 ± 4.0

20.2 ± 2.9

18.7 ± 4.0

0.01^*

0.00^*

43.0 ± 4.3

42.8 ± 3.9

42.5 ± 4.4

0.67

0.02^*

43.6 ± 8.7

43.7 ± 8.1

43.3 ± 8.7

0.97

0.05

42.9 ± 9.5

42.9 ± 8.9

42.2 ± 9.5

0.91

0.00^*